Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Düsing R et al. | Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. | 1983 | Am. J. Physiol. | pmid:6337507 |
Nordøy A et al. | Platelets and coagulation in patients with familial hypercholesterolemia (type IIa). | 1983 | Acta Med Scand | pmid:6188328 |
Kangasaho M et al. | Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6303086 |
Horellou MH et al. | Familial and constitutional bleeding disorder due to platelet cyclo-oxygenase deficiency. | 1983 | Am. J. Hematol. | pmid:6404162 |
Di Minno G et al. | Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: inhibition by a monoclonal antibody to the glycoprotein IIb-IIIa complex. | 1983 | Blood | pmid:6216929 |
Marcella JJ et al. | Exercise-induced myocardial ischemia in patients with coronary artery disease: lack of evidence for platelet activation or fibrin formation in peripheral venous blood. | 1983 | J. Am. Coll. Cardiol. | pmid:6339591 |
Brox JH et al. | Effects of cod liver oil on platelets and coagulation in familial hypercholesterolemia (type IIa). | 1983 | Acta Med Scand | pmid:6340424 |
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Hartung HP et al. | Stimulation of prostaglandin E and thromboxane synthesis in macrophages by purified C3b. | 1983 | J. Immunol. | pmid:6343486 |
Deckmyn H et al. | Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. | 1983 | Thromb. Res. | pmid:6344317 |
Ylikorkala O and Viinikka L | Prostaglandins and endometriosis. | 1983 | Acta Obstet Gynecol Scand Suppl | pmid:6344540 |
Ahlquist DA et al. | Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. | 1983 | Am. J. Physiol. | pmid:6401937 |
Kawaguchi H | Thromboxane synthesis in hypercholesterolemic platelets--on the mechanism of increased thromboxane synthesis. | 1983 | Hokkaido Igaku Zasshi | pmid:6618425 |
Jakubowski JA et al. | Arachidonic acid metabolism by platelets of differing size. | 1983 | Br. J. Haematol. | pmid:6402003 |
Dubin NH et al. | Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration. | 1983 | Biol. Reprod. | pmid:6626652 |
Nuotto E et al. | Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man. | 1983 | Eur. J. Clin. Pharmacol. | pmid:6628518 |
Hornstra G et al. | Dietary-fat-induced changes in the formation of prostanoids of the 2 and 3 series in relation to arterial thrombosis (rat) and atherosclerosis (rabbit). | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221593 |
Tremoli E et al. | North Karelian study: changes in dietary fat reduce thromboxane B2 formation by platelets only in male subjects--preliminary report. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221594 |
Basso N et al. | Gastric mucosal prostaglandin generation in rats with stress ulcer. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221618 |
Foegh M et al. | Prostacyclin and thromboxane release from human peritoneal macrophages. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221630 |
Westwick J et al. | Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221642 |
Sakamoto T | [Studies on platelet function in toxemia of pregnancy]. | 1983 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6223964 |
Winchester JF et al. | Early indicators of renal allograft rejection. | 1983 | Kidney Int. Suppl. | pmid:6224041 |
Dahl ML et al. | Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets. | 1983 | Prostaglandins Leukot Med | pmid:6415666 |
Han P et al. | Verapamil and collagen-induced platelet reactions--evidence for a role for intracellular calcium in platelet activation. | 1983 | Thromb. Haemost. | pmid:6415847 |
Barnhart MI et al. | DDAVP: does the drug have a direct effect on the vessel wall? | 1983 | Thromb. Res. | pmid:6415852 |
Wallis RB | Mechanisms of action of sulphinpyrazone. | 1983 | Thromb. Res. Suppl. | pmid:6415857 |
Wilson TW | Responses to furosemide in normotensive and hypertensive subjects. | 1983 | Clin. Pharmacol. Ther. | pmid:6688772 |
Gurtner GH et al. | Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6688802 |
van Rijk GL et al. | Long-term myocardial preservation: thromboxane production and coronary resistance. | 1983 | J. Surg. Res. | pmid:6688844 |
Miller JB et al. | Alterations in plasma and tissue prostaglandin levels in rabbits during luteal regression. | 1983 | Biol. Reprod. | pmid:6688954 |
Davì G et al. | The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects. | 1983 | Thromb. Haemost. | pmid:6417815 |
Muccitelli RM et al. | Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. | 1983 | Prostaglandins | pmid:6689082 |
Dale J et al. | The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. | 1983 | Thromb. Haemost. | pmid:6689091 |
Liu J | [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. | 1983 | Zhonghua Yi Xue Za Zhi | pmid:6418338 |
Aehringhaus U et al. | Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. | 1983 | Br. J. Pharmacol. | pmid:6689134 |
McDonald JW and Ali M | Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. | 1983 | Prostaglandins Leukot Med | pmid:6419234 |
Hartung HP et al. | Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. | 1983 | J. Immunol. | pmid:6600482 |
Zipser RD et al. | Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. | 1983 | Gastroenterology | pmid:6572162 |
Schenkelaars EJ and Bonta IL | Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages. | 1983 | Eur. J. Pharmacol. | pmid:6572592 |
Rocklin RE et al. | Augmentation of prostaglandin and thromboxane production in vitro by monocytes exposed to histamine-induced suppressor factor (HSF). | 1983 | Cell. Immunol. | pmid:6573232 |
Hoult JR and Robinson C | Selective inhibition of thromboxane B2 accumulation and metabolism in perfused guinea-pig lung. | 1983 | Br. J. Pharmacol. | pmid:6824820 |
Hirsh PD et al. | Effects of provocation on transcardiac thromboxane in patients with coronary artery disease. | 1983 | Am. J. Cardiol. | pmid:6829431 |
Walinsky P et al. | Beneficial effects of ibuprofen in pacing-induced myocardial ischemia. | 1983 | Am. J. Cardiol. | pmid:6829434 |
Roy L et al. | Increased plasma concentrations of prostacyclin metabolite 6-keto-PGF1 alpha in essential hypertension. Influence of therapy with labetalol. | 1983 | Am. J. Cardiol. | pmid:6823861 |
Poyser NL and Brydon LJ | Prostaglandin release from the guinea-pig uterus superfused in vitro. Effect of stage of estrous cycle, progesterone, estradiol, oxytocin and A23187. | 1983 | Prostaglandins | pmid:6408712 |
Laitinen O et al. | Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis. | 1983 | Clin. Rheumatol. | pmid:6589104 |
Ouwendijk RJ et al. | Raised plasma levels of thromboxane B2 in systemic mastocytosis. | 1983 | Eur. J. Clin. Invest. | pmid:6409646 |
Snapper JR et al. | Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. | 1983 | J. Clin. Invest. | pmid:6409930 |
Asbóth G et al. | Conversion of arachidonic acid to prostanoids in the avian uterus. | 1983 | Biochim. Biophys. Acta | pmid:6402032 |