Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yang CS and Zhang LZ | [Feto-placental microcirculation and pathologic changes of the chorionic villi in pregnancy-induced hypertension syndrome]. | 1988 | Zhonghua Yi Xue Za Zhi | pmid:3242757 |
Chen LB et al. | [Coagulation and prothrombotic state parameters: clinical analysis in early pregnancy]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24284247 |
Chen SY | [Correlation of platelet aggregation, platelet cAMP content and TXB2 synthesis in patients with diabetes mellitus]. | 1988 | Zhonghua Yi Xue Za Zhi | pmid:2853988 |
Huang Y and Liu YT | [Effects of anisodamine (654-2) on plasma levels of thromboxane B2, 6-keto-PGF1 alpha and platelet cAMP following cardiopulmonary bypass]. | 1988 | Zhonghua Yi Xue Za Zhi | pmid:2854751 |
Wang G | [Role of thromboxane A2 and prostacyclin in the pathophysiology of epidemic hemorrhagic fever]. | 1990 | Zhonghua Yi Xue Za Zhi | pmid:1977503 |
Liu J | [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. | 1983 | Zhonghua Yi Xue Za Zhi | pmid:6418338 |
Cai D et al. | [Changes in cytosolic free calcium and thromboxane B2 synthesis in platelets from diabetic subjects]. | 1995 | Zhonghua Yi Xue Za Zhi | pmid:7584570 |
Zhu YY | [Action of prostaglandin-like substances in rabbits with acute lung lesions]. | 1987 | Zhonghua Yi Xue Za Zhi | pmid:3123036 |
Shen J | [Effects of verapamil on prostacyclin, thromboxane and pancreatic blood flow of rats with experimental acute pancreatitis]. | 1991 | Zhonghua Yi Xue Za Zhi | pmid:1660773 |
Yao HX et al. | [The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia]. | 2010 | Zhonghua Yi Xue Za Zhi | pmid:20356540 |
P'eng FK et al. | Pulmonary edema and rapid transfusion: the comparison between rapid intravenous and intraarterial infusion in the severely hemorrhagic anesthesized pigs. | 1994 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:7954050 |
Liu W et al. | [Effects of selenium and vitamin E on arachidonic acid metabolism in experimental myocardial ischaemia]. | 1995 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:8556938 |
Wang BZ et al. | [Association of Rs10487667 genetic polymorphism of thromboxane synthase with myocardial infarction in Uigur population of Xinjiang]. | 2010 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:21215134 |
Chen G et al. | [The effect of the molecular triggers of hemostatic activity on thrombosis in early stage of electrical injuries]. | 1999 | Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi | pmid:11501103 |
Huang YS | [Clinical study on main visceral damage and multiple organ failure (MOF) following severe burns]. | 1993 | Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi | pmid:8402345 |
Huang YS | [Myocardial damage and its mechanism in burn patients]. | 1993 | Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi | pmid:8221314 |
Yang ZC | [Clinical study of the pathogeneses of multiple organ failure after burns]. | 1992 | Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi | pmid:1596797 |