Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Tai HH and Yuan B | Development of radioimmunoassay for thromboxane B2. | 1978 | Anal. Biochem. | pmid:567443 |
Murota S and Morita I | Effect of prostaglandin I2 and related compounds on vascular permeability response in granuloma tissues. | 1978 | Prostaglandins | pmid:635221 |
Powell WS and Solomon S | Biosynthesis of prostaglandins and thromboxane B2 by fetal lung homogenates. | 1978 | Prostaglandins | pmid:635224 |
Tai HH et al. | Transformation of arachidonate into 6-oxoprostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 by sheep lung microsomal fraction. | 1978 | Biochem. J. | pmid:637853 |
Murota SI et al. | Transformation of arachidonic acid into thromboxane B2 by the homogenates of activated macrophages. | 1978 | Biochim. Biophys. Acta | pmid:638172 |
Mallen DN et al. | Structural verification of 15-oxo-13,14-dihydrothromboxane B2. | 1978 | Biomed. Mass Spectrom. | pmid:678616 |
Morita I et al. | Characterization of thromboxane B2 and 6-ketoprostaglandin F alpha by combined gas chromatography and chemical-ionization mass spectrometry. | 1978 | J. Chromatogr. | pmid:681479 |
Nelson NA et al. | Synthesis of thromboxane B2 metabolites. | 1978 | Prostaglandins | pmid:704927 |
Marion J and Wolfe LS | Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. | 1978 | Prostaglandins | pmid:704928 |
Kitchen EA et al. | Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. | 1978 | Prostaglandins | pmid:704931 |
Sors H et al. | Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. | 1978 | Prostaglandins | pmid:704933 |
Turk J et al. | Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. | 1978 | Prostaglandins | pmid:704934 |
Raz A and Aharony D | Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. | 1978 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:705027 |
Chang WC et al. | Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma. | 1978 | Biochem. Pharmacol. | pmid:619892 |
Goetzl EJ and Gorman RR | Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT). | 1978 | J. Immunol. | pmid:621391 |
Mitchell MD et al. | Thromboxane B2 and human parturition: concentrations in the plasma and production in vitro. | 1978 | J. Endocrinol. | pmid:712300 |
Malik KU | Prostaglandin-mediated inhibition of the vasoconstrictor responses of the isolated perfused art splenic vasculature to adrenergic stimuli. | 1978 | Circ. Res. | pmid:27321 |
Hamberg M et al. | A method for measurement of platelet regeneration in man. | 1978 | Prostaglandins Med | pmid:104315 |
Lagarde M et al. | Impairment of platelet thromboxane A2 generation and of the platelet release reaction in two patients with congenital deficiency of platelet cyclo-oxygenase. | 1978 | Br. J. Haematol. | pmid:205238 |
Crawford A et al. | Rat osteogenic sarcoma cells: comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1alpha and thromboxane B2 on cyclic AMP production and adenylate cyclase activity. | 1978 | Biochem. Biophys. Res. Commun. | pmid:212039 |