Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pestel S et al. | Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. | 2003 | Biochem. Pharmacol. | pmid:12906929 |
| De La Cruz P et al. | Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12595963 |
| Uchida M et al. | Changes in cerebral microcirculation during and after abdominal aortic cross-clamping in rabbits: the role of thromboxane A2 receptor. | 2003 | Anesth. Analg. | pmid:12598238 |
| Zaitsu M et al. | Thromboxane synthesis is increased by upregulation of cytosolic phospholipase A2 and cyclooxygenase-2 in peripheral polymorphonuclear leukocytes during bacterial infection in childhood. | 2003 | Am. J. Hematol. | pmid:12555215 |
| Kirchheiner J et al. | Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans. | 2003 | Br J Clin Pharmacol | pmid:12534640 |
| von Aulock S et al. | Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivo. | 2003 | J. Immunol. Methods | pmid:12799039 |
| Cabrera DM et al. | A thromboxane A(2) system in the Atlantic stingray, Dasyatis sabina. | 2003 | Gen. Comp. Endocrinol. | pmid:12568793 |
| Nemr R et al. | Effects of nicotine on thromboxane/prostacyclin balance in myocardial ischemia. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591002 |
| Yregård L et al. | Influence of local anaesthetics on inflammatory activity postburn. | 2003 | Burns | pmid:12781610 |
| Ersöz G et al. | Effect of sodium selenite treatment on platelet aggregation of streptozotocin-induced diabetic rats. | 2003 | Thromb. Res. | pmid:14698654 |
| Wu X et al. | Zileuton, a 5-lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma. | 2003 | Am. J. Hematol. | pmid:12949886 |
| Bosetti F et al. | Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. | 2003 | J. Neurochem. | pmid:12694395 |
| Tanaka Y et al. | Effects of exercise on platelet and aortic functions in aged rats. | 2003 | Acta Physiol. Scand. | pmid:14510779 |
| Chen L et al. | Cyclooxygenase inhibitor blocks rebound response after NO inhalation in an endotoxin model. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12485821 |
| Wolfram R et al. | Daily prickly pear consumption improves platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12878452 |
| Yu CC and Lai YL | Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. | 2003 | Life Sci. | pmid:12927588 |
| Zhuang HP et al. | [Effect of aspirin combined with perindopril on prostacyclin, thromboxone A2, and norepinephrine in the blood of arteriosclerosis rabbit models and the cardiac function]. | 2003 | Hunan Yi Ke Da Xue Xue Bao | pmid:12934393 |
| Castellani S et al. | Thromboxane inhibition improves renal perfusion and excretory function in severe congestive heart failure. | 2003 | J. Am. Coll. Cardiol. | pmid:12849673 |
| Pettus BJ et al. | Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. | 2003 | J. Biol. Chem. | pmid:12855693 |
| Shimada N et al. | Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients. | 2003 | Ren Fail | pmid:12911161 |
| Patrono C | Aspirin resistance: definition, mechanisms and clinical read-outs. | 2003 | J. Thromb. Haemost. | pmid:12911581 |
| Villalobos MA et al. | Effects of camonagrel, a selective inhibitor of platelet thromboxane synthase, on the platelet-subendothelium interaction. | 2003 | Pharmacology | pmid:12886030 |
| Miceli M et al. | Effect of low doses of ethanol on platelet function in long-life abstainers and moderate-wine drinkers. | 2003 | Life Sci. | pmid:12865095 |
| Kankuri E et al. | Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. | 2003 | Thromb. Res. | pmid:14592552 |
| Heller AR et al. | Clusterin protects the lung from leukocyte-induced injury. | 2003 | Shock | pmid:12865662 |
| Zhang C et al. | Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. | 2003 | J. Hypertens. | pmid:14597858 |
| Wang ZF et al. | The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids. | 2003 | HBPD INT | pmid:14599960 |
| Eder K et al. | Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells. | 2003 | J. Nutr. | pmid:14652352 |
| Li JS et al. | [Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia]. | 2003 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:14552688 |
| Lombard JH et al. | High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12456391 |
| Al-Waili NS and Boni NS | Natural honey lowers plasma prostaglandin concentrations in normal individuals. | 2003 | J Med Food | pmid:12935324 |
| Jones AE et al. | Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12639842 |
| Davì G et al. | Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. | 2003 | Circulation | pmid:12810609 |
| Bellou A et al. | Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock. | 2003 | Shock | pmid:12558148 |
| De La Cruz JP et al. | Differences in the effects of extended-release aspirin and plain-formulated aspirin on prostanoids and nitric oxide in healthy volunteers. | 2003 | Fundam Clin Pharmacol | pmid:12803576 |
| Guyton K et al. | Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli. | 2003 | Shock | pmid:12813370 |
| Montuschi P et al. | Exhaled leukotrienes and prostaglandins in COPD. | 2003 | Thorax | pmid:12832671 |
| Fujimoto Y et al. | Effects of endocrine disruptors on arachidonic acid metabolism in rabbit platelets. | 2003 | Toxicol. Appl. Pharmacol. | pmid:12781627 |
| Stephenson AH et al. | Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12609822 |
| Beck-Speier I et al. | Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518563 |
| Cipollone F et al. | Modulation of aspirin-insensitive eicosanoid biosynthesis by 6-methylprednisolone in unstable angina. | 2003 | Circulation | pmid:12515743 |
| Halushka MK et al. | Genetic variation in cyclooxygenase 1: effects on response to aspirin. | 2003 | Clin. Pharmacol. Ther. | pmid:12545150 |
| Huang RJ et al. | [Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764908 |
| Li ZG et al. | [Progress on study of experimental physico-chemical indexes related with ischemic stroke]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764922 |
| Lei D et al. | Antioxidative and antiplatelet effects of aqueous inflorescence Piper betle extract. | 2003 | J. Agric. Food Chem. | pmid:12643677 |
| Park WH et al. | The antiplatelet activity of Geiji-Bokryung-Hwan, Korean traditional formulation, is mediated through inhibition of phospholipase C and inhibition of TxB(2) synthetase activity. | 2003 | Int. Immunopharmacol. | pmid:12810354 |
| Hou X et al. | Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity. | 2003 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12626359 |
| Tsuruta LR et al. | Characterization of 11-dehydro-thromboxane B2 recombinant antibody obtained by phage display technology. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12628223 |
| Meune C et al. | Aspirin alters arterial function in patients with chronic heart failure treated with ACE inhibitors: a dose-mediated deleterious effect. | 2003 | Eur. J. Heart Fail. | pmid:12798824 |
| Nagase T et al. | A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12505870 |