Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hansen TN and Brockbank KG | Increased platelet aggregation due to chilling to 20 degrees C is not related to increased sensitivity to agonists. | 1997 | Transfusion | pmid:9225932 |
Suchkova V | Prostanoid and anti-thrombin III levels in premature infants. | 1997 | Adv. Exp. Med. Biol. | pmid:9547655 |
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Kobayashi T et al. | Changes in platelet calcium concentration by thromboxane A2 stimulation in patients with nephrotic syndrome of childhood. | 1997 | Nephron | pmid:9375825 |
Chavali SR et al. | Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. | 1997 | Int. Arch. Allergy Immunol. | pmid:9338609 |
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Supanz S et al. | Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat. | 1997 | Arzneimittelforschung | pmid:9342416 |
Tulppala M et al. | Low-dose aspirin in prevention of miscarriage in women with unexplained or autoimmune related recurrent miscarriage: effect on prostacyclin and thromboxane A2 production. | 1997 | Hum. Reprod. | pmid:9262298 |
Nanji AA et al. | Alterations in thromboxane synthase and thromboxane A2 receptors in experimental alcoholic liver disease. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9262373 |
De La Cruz JP et al. | Effects of S-adenosyl-L-methionine on platelet thromboxane and vascular prostacyclin. | 1997 | Biochem. Pharmacol. | pmid:9264331 |
Siler-Khodr TM et al. | The effect of dexamethasone on CRH and prostanoid production from human term placenta. | 1997 | Prostaglandins | pmid:9373879 |
Serebruany VL et al. | Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor? | 1997 | Mol. Aspects Med. | pmid:9266521 |
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Gresele P et al. | Platelet activation markers in patients with peripheral arterial disease--a prospective comparison of different platelet function tests. | 1997 | Thromb. Haemost. | pmid:9423790 |
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Szebeni J et al. | Complement activation and thromboxane secretion by liposome-encapsulated hemoglobin in rats in vivo: inhibition by soluble complement receptor type 1. | 1997 | Artif Cells Blood Substit Immobil Biotechnol | pmid:9242930 |
He CF et al. | Postural vasoregulation and mediators of reperfusion injury in venous ulceration. | 1997 | J. Vasc. Surg. | pmid:9129619 |
González E et al. | Influence of nitric oxide synthase and kinin antagonists on metabolic parameters in chronic streptozotocin-induced diabetes mellitus. | 1997 | Prostaglandins | pmid:9247972 |
Brinkmann A et al. | The impact of prostanoids on pulmonary gas exchange during abdominal surgery with mesenteric traction. | 1997 | Anesth. Analg. | pmid:9249099 |
Baskett A et al. | Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. | 1997 | Am. J. Vet. Res. | pmid:9361895 |
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John H and Schlegel W | Reversed-phase high-performance liquid chromatographic method for the determination of the 11-hydroxythromboxane B2 anomers equilibrium. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9367188 |
Capponi A et al. | Indomethacin modifies the fetal hemodynamic response induced by percutaneous umbilical blood sampling. | 1997 | Am. J. Obstet. Gynecol. | pmid:9369815 |
Fujita M et al. | Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs. | 1997 | Jpn. J. Pharmacol. | pmid:9469640 |
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Cervar M et al. | Drug actions in preeclampsia: aspirin, but not magnesium chloride or dihydralazine, differentially inhibits cultured human trophoblast release of thromboxane and prostacyclin without affecting angiotensin II, endothelin-1, or leukotriene B4 secretion. | 1997 | Am. J. Obstet. Gynecol. | pmid:9024091 |
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Abate A et al. | Inhibition of mediator release from anaphylactic guinea pig hearts by the novel phospholipase A2 inhibitor 3-(4-octadecylbenzoyl) acrylic acid. | 1997 | Inflamm. Res. | pmid:9297549 |
Slepko N et al. | Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture. | 1997 | J. Neurosci. Res. | pmid:9260740 |
Davì G et al. | Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease. | 1997 | Circulation | pmid:9236419 |
Yanagisawa H et al. | Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys. | 1997 | Kidney Blood Press. Res. | pmid:9453451 |
Johnson RD et al. | Aspirin induces increased expression of both prostaglandin H synthase-1 and prostaglandin H synthase-2 in cultured human placental trophoblast. | 1997 | Am. J. Obstet. Gynecol. | pmid:9240586 |
Fujinishi A et al. | Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease. | 1997 | Angiology | pmid:9194537 |
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