Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Pneumonia, Viral D011024 3 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Menorrhagia D008595 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Diseases in Twins D004200 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Santillan-Doherty P et al. Plasma thromboxane B2 concentrations and pulmonary vascular resistance during lung reperfusion. 1997 Jul-Aug J Invest Surg pmid:9284000
Teraoka S et al. Multicenter trial of the therapeutic effect of a newly developed antiplatelet agent, satigrel, on biopsy-proven chronic rejection after kidney transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9122990
Ishine N et al. Hemodynamic analysis of post-reperfusion syndrome and the effect of preventing this syndrome using thromboxane A2 synthetase inhibitor (OKY-046) in swine liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123045
Suehiro T et al. Value of caval effluent in predicting early graft function after orthotopic liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123086
Yagi T et al. Hepatropic soluble vitamin E derivative EPC-K1 prevents warm ischemia/reperfusion injury of non-heart-beating donor liver transplantation in pigs. 1997 Feb-Mar Transplant. Proc. pmid:9123352
Yamamoto S et al. Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock. 1997 Am. J. Physiol. pmid:9087598
Kume S [Evaluation and problems on platelet function tests]. 1997 Nippon Rinsho pmid:9097565
Schorer AE Discordant effects on eicosanoids and fibrin degradation products in two murine models of antiphospholipid antibody. 1997 Thromb. Res. pmid:9062953
Teng CM et al. ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb. 1997 Thromb. Haemost. pmid:9066010
Tanabe K et al. Erythrocyte magnesium and prostaglandin dynamics in chronic sleep deprivation. 1997 Clin Cardiol pmid:9068914
Yu J and Hu WS [Effects of neferine on platelet aggregation in rabbits]. 1997 Yao Xue Xue Bao pmid:11243209
Held HD et al. Phosphodiesterase inhibitors prevent endothelin-1-induced vasoconstriction, bronchoconstriction, and thromboxane release in perfused rat lung. 1997 Biochem. Biophys. Res. Commun. pmid:9070212
Hellyer PW et al. Effect of NG-nitro-L-arginine-methyl-ester on cardiopulmonary function and biosynthesis of cyclooxygenase products during porcine endotoxemia. 1997 Crit. Care Med. pmid:9201060
Oelkers R et al. Disposition and effects of flurbiprofen enantiomers in human serum and blister fluid. 1997 Br J Clin Pharmacol pmid:9131946
Olson KR et al. Cardiovascular effects of homologous bradykinin in rainbow trout. 1997 Am. J. Physiol. pmid:9140009
Nanji AA et al. Thromboxane inhibitors attenuate pathological changes in alcoholic liver disease in the rat. 1997 Gastroenterology pmid:8978360
Berg J et al. Isoenzyme-specific cyclooxygenase inhibitors: a whole cell assay system using the human erythroleukemic cell line HEL and the human monocytic cell line Mono Mac 6. 1997 J Pharmacol Toxicol Methods pmid:9279772
Tanaka M et al. Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats. 1997 Biol. Neonate pmid:9303217
Davi G et al. In vivo formation of 8-Epi-prostaglandin F2 alpha is increased in hypercholesterolemia. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9409316
Bishop-Bailey D et al. Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat aorta in organ culture. 1997 Br. J. Pharmacol. pmid:9146896
Shinohara M et al. [Responses to surgical stress in blood coagulation and fibrinolysis, platelet counts and thromboxane B2 after esophageal cancer operation]. 1997 Rinsho Byori pmid:9121003
Cheng Z et al. Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats. 1997 Vet. Rec. pmid:9123796
Yasui K et al. Involvement of thromboxane A2 in antigen-induced nasal blockage in guinea pigs. 1997 Int. Arch. Allergy Immunol. pmid:9104797
Ringdahl BE et al. Effect of nicotine on arachidonic acid metabolites and epithelial parameters in rat oral mucosa. 1997 J. Oral Pathol. Med. pmid:9021551
Yamamura S et al. Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging. 1997 Cancer pmid:9010098
Nygaard OP et al. The inflammatory properties of contained and noncontained lumbar disc herniation. 1997 Spine pmid:9383853
Calzada C et al. Low concentrations of lipid hydroperoxides prime human platelet aggregation specifically via cyclo-oxygenase activation. 1997 Biochem. J. pmid:9230133
Oosaki R et al. Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. 1997 Allergy pmid:9188934
Zingarelli B et al. The inhibitory effects of mercaptoalkylguanidines on cyclo-oxygenase activity. 1997 Br. J. Pharmacol. pmid:9031736
Watanabe A et al. Effect of TYB-2285 on lung anaphylaxis in actively sensitized rats. 1997 Gen. Pharmacol. pmid:9013209
Lewis DA et al. Production of endothelium-derived factors from sodded expanded polytetrafluoroethylene grafts. 1997 J. Vasc. Surg. pmid:9013924
Liu CZ and Huang TF Crovidisin, a collagen-binding protein isolated from snake venom of Crotalus viridis, prevents platelet-collagen interaction. 1997 Arch. Biochem. Biophys. pmid:9016825
Yeh SL et al. Effects of n-3 and n-6 fatty acids on plasma eicosanoids and liver antioxidant enzymes in rats receiving total parenteral nutrition. 1997 Nutrition pmid:9058445
Feng J et al. Effects of tetramethylpyrazine on the release of PGI2 and TXA2 in the hypoxic isolated rat heart. 1997 Mol. Cell. Biochem. pmid:9059992
Wettstein M and Häussinger D Cytoprotection by the osmolytes betaine and taurine in ischemia-reoxygenation injury in the perfused rat liver. 1997 Hepatology pmid:9397998
Hansen TN and Brockbank KG Increased platelet aggregation due to chilling to 20 degrees C is not related to increased sensitivity to agonists. 1997 Transfusion pmid:9225932
Suchkova V Prostanoid and anti-thrombin III levels in premature infants. 1997 Adv. Exp. Med. Biol. pmid:9547655
Moutquin JM et al. Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study. 1997 Am. J. Obstet. Gynecol. pmid:9423755
Rautanen M et al. Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs. 1997 Crit. Care Med. pmid:9233750
Henrion D et al. Alteration of flow-induced dilatation in mesenteric resistance arteries of L-NAME treated rats and its partial association with induction of cyclo-oxygenase-2. 1997 Br. J. Pharmacol. pmid:9146891
Lahoz C et al. Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure. 1997 Eur. J. Clin. Invest. pmid:9352251
Kobayashi T et al. Changes in platelet calcium concentration by thromboxane A2 stimulation in patients with nephrotic syndrome of childhood. 1997 Nephron pmid:9375825
Chavali SR et al. Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. 1997 Int. Arch. Allergy Immunol. pmid:9338609
Neupert W et al. Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases. 1997 Br. J. Pharmacol. pmid:9351505
Zahavi M and Zahavi J Concomitant in vitro platelet hypofunction and increased thromboxane B2 (TXB2) generation and enhanced in vivo platelet activation. A distinct syndrome in thrombosis? 1997 Eur. J. Haematol. pmid:9338626
Supanz S et al. Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat. 1997 Arzneimittelforschung pmid:9342416
Tulppala M et al. Low-dose aspirin in prevention of miscarriage in women with unexplained or autoimmune related recurrent miscarriage: effect on prostacyclin and thromboxane A2 production. 1997 Hum. Reprod. pmid:9262298
Nanji AA et al. Alterations in thromboxane synthase and thromboxane A2 receptors in experimental alcoholic liver disease. 1997 J. Pharmacol. Exp. Ther. pmid:9262373
De La Cruz JP et al. Effects of S-adenosyl-L-methionine on platelet thromboxane and vascular prostacyclin. 1997 Biochem. Pharmacol. pmid:9264331
Siler-Khodr TM et al. The effect of dexamethasone on CRH and prostanoid production from human term placenta. 1997 Prostaglandins pmid:9373879
Serebruany VL et al. Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor? 1997 Mol. Aspects Med. pmid:9266521
Li S and Tian H [Oral low-dose magnesium gluconate preventing pregnancy induced hypertension]. 1997 Zhonghua Fu Chan Ke Za Zhi pmid:9642379
Gresele P et al. Platelet activation markers in patients with peripheral arterial disease--a prospective comparison of different platelet function tests. 1997 Thromb. Haemost. pmid:9423790
Berlin I et al. [Comparison between effects of morning and evening administration of effervescent calcium carbasalate (equivalent of 160 mg aspirin) on the gastroduodenal mucosa in healthy volunteers]. 1997 Pathol. Biol. pmid:9309270
Famaey JP In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. 1997 Inflamm. Res. pmid:9427063
Szebeni J et al. Complement activation and thromboxane secretion by liposome-encapsulated hemoglobin in rats in vivo: inhibition by soluble complement receptor type 1. 1997 Artif Cells Blood Substit Immobil Biotechnol pmid:9242930
He CF et al. Postural vasoregulation and mediators of reperfusion injury in venous ulceration. 1997 J. Vasc. Surg. pmid:9129619
González E et al. Influence of nitric oxide synthase and kinin antagonists on metabolic parameters in chronic streptozotocin-induced diabetes mellitus. 1997 Prostaglandins pmid:9247972
Brinkmann A et al. The impact of prostanoids on pulmonary gas exchange during abdominal surgery with mesenteric traction. 1997 Anesth. Analg. pmid:9249099
Baskett A et al. Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. 1997 Am. J. Vet. Res. pmid:9361895
Shen ZQ et al. Inhibitory effects of copper-aspirin complex on platelet aggregation. 1997 Zhongguo Yao Li Xue Bao pmid:10072923
Barton MH et al. Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin. 1997 Am. J. Vet. Res. pmid:9361896
Moser L et al. ACE inhibitor effects on platelet function in stages I-II hypertension. 1997 J. Cardiovasc. Pharmacol. pmid:9335405
Zeng S and Guo ZG Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine. 1997 Zhongguo Yao Li Xue Bao pmid:10072970
Chen L et al. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. 1997 Am. J. Physiol. pmid:9362253
Li W et al. [Influence of qi-gong on plasma TXB2 and 6-keto-PGF1 alpha in two TCM types of essential hypertension]. 1997 Hunan Yi Ke Da Xue Xue Bao pmid:10072988
Bar J et al. The regulation of platelet aggregation in vitro by interleukin-1beta and tumor necrosis factor-alpha: changes in pregnancy and in pre-eclampsia. 1997 Thromb. Haemost. pmid:9364994
Hashimoto Y et al. Characteristics of protein kinase C-independent exocytosis in human platelets. 1997 Thromb. Res. pmid:9336873
Yi Z et al. [Changes and evaluation of indexes on treating ganyanghuafengzheng with cerebral infarction by tianlongxifeng granulae]. 1997 Hunan Yi Ke Da Xue Xue Bao pmid:10073023
Walker JS et al. Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis: support for the concept of "responders" and "nonresponders". 1997 Arthritis Rheum. pmid:9365082
Low-dose aspirin in polycythaemia vera: a pilot study. Gruppo Italiano Studio Policitemia (GISP). 1997 Br. J. Haematol. pmid:9163613
Klosterhalfen B et al. The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia. 1997 Shock pmid:9165671
John H and Schlegel W Reversed-phase high-performance liquid chromatographic method for the determination of the 11-hydroxythromboxane B2 anomers equilibrium. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9367188
Capponi A et al. Indomethacin modifies the fetal hemodynamic response induced by percutaneous umbilical blood sampling. 1997 Am. J. Obstet. Gynecol. pmid:9369815
Fujita M et al. Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs. 1997 Jpn. J. Pharmacol. pmid:9469640
Savla U et al. Cyclic stretch of airway epithelium inhibits prostanoid synthesis. 1997 Am. J. Physiol. pmid:9374729
Cervar M et al. Drug actions in preeclampsia: aspirin, but not magnesium chloride or dihydralazine, differentially inhibits cultured human trophoblast release of thromboxane and prostacyclin without affecting angiotensin II, endothelin-1, or leukotriene B4 secretion. 1997 Am. J. Obstet. Gynecol. pmid:9024091
van Kooten F et al. Platelet activation and lipid peroxidation in patients with acute ischemic stroke. 1997 Stroke pmid:9259748
Sun ZT et al. [Clinical and experimental study on treating bronchial asthma with xingbei granule]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9863090
Zhang XY and Qian XM [Clinical study of sudden deafness treated with method of integrated traditional Chinese and Western medicine]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9863112
Wu JX et al. [Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9863132
Hu DH et al. [Effects of hypoxia and anisodamine on products of TXA2 and PGI2 in cultured intra-pulmonary arteriolar smooth muscle cells]. 1997 Sheng Li Xue Bao pmid:9863190
Li HP et al. [The relationship between the activity of phospholipase A2 and acute hypoxic pulmonary arterial pressure]. 1997 Sheng Li Xue Bao pmid:9863193
Farker K et al. Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women. 1997 Prostaglandins pmid:9373880
Matrougui K et al. Impaired nitric oxide- and prostaglandin-mediated responses to flow in resistance arteries of hypertensive rats. 1997 Hypertension pmid:9336397
Oosaki R et al. Urinary excretion of leukotriene E4 and 11-dehydrothromboxane B2 in patients with spontaneous asthma attacks. 1997 Int. Arch. Allergy Immunol. pmid:9414142
Davì G et al. Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group. 1997 Am. J. Respir. Crit. Care Med. pmid:9412557
Teng CM et al. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. 1997 J. Pharm. Pharmacol. pmid:9255715
Abate A et al. Inhibition of mediator release from anaphylactic guinea pig hearts by the novel phospholipase A2 inhibitor 3-(4-octadecylbenzoyl) acrylic acid. 1997 Inflamm. Res. pmid:9297549
Slepko N et al. Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture. 1997 J. Neurosci. Res. pmid:9260740
Davì G et al. Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease. 1997 Circulation pmid:9236419
Yanagisawa H et al. Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys. 1997 Kidney Blood Press. Res. pmid:9453451
Johnson RD et al. Aspirin induces increased expression of both prostaglandin H synthase-1 and prostaglandin H synthase-2 in cultured human placental trophoblast. 1997 Am. J. Obstet. Gynecol. pmid:9240586
Fujinishi A et al. Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease. 1997 Angiology pmid:9194537
Freese R and Mutanen M Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. 1997 Am. J. Clin. Nutr. pmid:9280178
Riendeau D et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. 1997 Br. J. Pharmacol. pmid:9146894
Cook ME et al. Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. 1997 J. Rheumatol. pmid:9195523
Hato T et al. Outside-in signaling from integrin alpha IIb beta 3 into platelets in the absence of agonist-induced signaling. 1997 Int. J. Hematol. pmid:9195778
Hishinuma T et al. Microdetermination of the thromboxane B3 gas chromatography-selected-ion monitoring using [18O]thromboxane B3 as an internal standard. 1997 Prostaglandins pmid:9261859
Riendeau D et al. Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. 1997 Can. J. Physiol. Pharmacol. pmid:9365818