Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Theriot JA et al. | Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. | 2000 | J. Lab. Clin. Med. | pmid:10850649 |
Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
Tran HS et al. | The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. | 2000 | Shock | pmid:10847636 |
Rioja I et al. | An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. | 2000 | Eur. J. Pharmacol. | pmid:10844115 |
Cracowski JL et al. | Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. | 2000 | Eur. J. Pharmacol. | pmid:10844110 |
Sakamoto K et al. | An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm. | 1999 | Eur. Respir. J. | pmid:10836338 |
Numminen H et al. | The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. | 2000 | Stroke | pmid:10835443 |
Semenov AV et al. | [Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension]. | 2000 | Ter. Arkh. | pmid:10833791 |
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Nosál' R et al. | Chloroquine: a multipotent inhibitor of human platelets in vitro. | 2000 | Thromb. Res. | pmid:10828481 |
Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. | 2000 | Thromb. Haemost. | pmid:10823277 |
Romano M et al. | Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. | 2000 | J. Investig. Med. | pmid:10822898 |
Turpeinen AM et al. | Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. | 2000 | Eur J Clin Nutr | pmid:10822290 |
Tanus-Santos JE et al. | Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. | 2000 | Eur. J. Pharmacol. | pmid:10822051 |
Jacobi KE et al. | Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. | 2000 | J Clin Anesth | pmid:10818321 |
Gardan B et al. | Vasoconstrictor effects of iso-prostaglandin F2alpha type-III (8-iso-prostaglandin F2alpha) on human saphenous veins. | 2000 | J. Cardiovasc. Pharmacol. | pmid:10813374 |
Wakitani K et al. | JTE-522 selectively inhibits cyclooxygenase-2-derived prostaglandin production in inflammatory tissues. | 2000 | Inflamm. Res. | pmid:10807499 |
Zhao S et al. | Glioma prostaglandin levels correlate with brain edema. | 1998 | J. Tongji Med. Univ. | pmid:10806839 |
Jacobs C et al. | 1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase. | 2000 | J. Med. Chem. | pmid:10794700 |
Agnoli GC et al. | Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780876 |
Heller A et al. | The complement regulators C1 inhibitor and soluble complement receptor 1 attenuate acute lung injury in rabbits. | 2000 | Shock | pmid:10774617 |
Prieto MA et al. | Influence of triflusal on platelet activation after coronary artery bypass graft. | 2000 | Blood Coagul. Fibrinolysis | pmid:10759013 |
Liao CH et al. | Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets. | 2000 | J. Pharm. Pharmacol. | pmid:10757426 |
Bailey SR et al. | Actions and interactions of ADP, 5- HT, histamine and PAF on equine platelets. | 2000 | Res. Vet. Sci. | pmid:10756136 |
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Schweizer A et al. | Aprotinin does not impair renal haemodynamics and function after cardiac surgery. | 2000 | Br J Anaesth | pmid:10740541 |
Homoncik M et al. | Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. | 2000 | Thromb. Haemost. | pmid:10739392 |
Jacobi K et al. | Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. | 2000 | Vox Sang. | pmid:10729809 |