Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Spagnuolo PJ et al. | Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. | 1980 | J. Clin. Invest. | pmid:6772674 |
Best LC et al. | The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro. | 1980 | Thromb. Haemost. | pmid:6773171 |
Olund A et al. | Prostaglandins and thromboxanes in amniotic fluid during rivanol-induced abortion and labour. | 1980 | Prostaglandins | pmid:6775353 |
Stuart MJ et al. | The influence of albumin and calcium on human platelet arachidonic acid metabolism. | 1980 | Blood | pmid:6766753 |
Challis JR and Patrick JE | The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. | 1980 | Semin. Perinatol. | pmid:6992278 |
Ahnfelt-Rønne I et al. | Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. | 1980 | Agents Actions | pmid:6992544 |
Gullner HG et al. | Correction of increased prostacyclin synthesis in Bartter's syndrome by indomethacin treatment. | 1980 | Prostaglandins Med | pmid:6994153 |
Crutchley DJ et al. | Enhanced thromboxane B2 release from challenged guinea pig lung after oxygen exposure. | 1980 | Am. Rev. Respir. Dis. | pmid:6155814 |
Cella G et al. | In vivo platelet release reaction in patients with heart valve prosthesis. | 1980 | Haemostasis | pmid:6157609 |
Best LC et al. | Lanthanum stimulates the accumulation of cyclic AMP and inhibits secretion and thromboxane B2 formation in human platelets. | 1980 | Biochim. Biophys. Acta | pmid:6251913 |
Heggers JP et al. | Evaluation of burn blister fluid. | 1980 | Plast. Reconstr. Surg. | pmid:6770396 |
Galli C et al. | Effects of 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy carboxyl methoxy coumarin (AD6) on aggregation, arachidonic acid metabolism and thromboxane B2 formation in human platelets. | 1980 | Pharmacol Res Commun | pmid:7393988 |
Oka M and Manku MS | Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets. | 1980 | Prostaglandins Med | pmid:7394062 |
Karmali RA et al. | Intrarenal growth of the Walker 256 tumour and renal vein concentrations of PGE2, PGF 2 alpha, and TXB2: effects of diazepam. | 1980 | Prostaglandins Med | pmid:7394064 |
Bailey JM | Essential fatty acid requirements and metabolism of cells in tissue culture. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386288 |
Cook JA et al. | Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. | 1980 | J. Clin. Invest. | pmid:7350199 |
Stuart MJ et al. | Effect of cholesterol on production of thromboxane b2 by platelets in vitro. | 1980 | N. Engl. J. Med. | pmid:7350406 |
Maclouf J et al. | Interactions of prostaglandin H2 and thromboxane A2 with human serum albumin. | 1980 | Eur. J. Biochem. | pmid:7408901 |
Vanderhoek JY et al. | 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. | 1980 | J. Biol. Chem. | pmid:6771259 |
Ali M et al. | Inhibition of human platelet cyclooxygenase by alpha-tocopherol. | 1980 | Prostaglandins Med | pmid:6771778 |