Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
Asthma D001249 52 associated lipids
Kidney Diseases D007674 29 associated lipids
Femoral Fractures D005264 7 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Barnett AH et al. Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes. 1984 Lancet pmid:6145027
Schenkelaars EJ and Bonta IL Beta 2-adrenoceptor agonists reverse the leukotriene C4-induced release response of macrophages. 1984 Eur. J. Pharmacol. pmid:6151905
Kopolovic R et al. Effects of ibuprofen on a porcine model of acute respiratory failure. 1984 J. Surg. Res. pmid:6708494
Schenkein HA and Rutherford B C3-mediated release of prostaglandin from human monocytes. Behaviour in short-term culture. 1984 Immunology pmid:6690398
Hamasaki Y et al. Platelet-activating factor raises airway and vascular pressures and induces edema in lungs perfused with platelet-free solution. 1984 Am. Rev. Respir. Dis. pmid:6547031
Gallenkämper W et al. Cardioprotective actions of pentoxifylline in an animal model of acute myocardial ischaemia. 1984 Br. J. Pharmacol. pmid:6547067
Coker SJ and Parratt JR The effects of timolol on arrhythmias and prostanoid release during canine myocardial ischaemia and reperfusion. 1984 Br. J. Pharmacol. pmid:6547068
Navran SS et al. Human platelet activation by bacterial phospholipase C is mediated by phosphatidylinositol hydrolysis but not generation of phosphatidic acid: inhibition by a selective inhibitor of phospholipase C. 1984 Thromb. Res. pmid:6372157
Furman BL et al. Failure of drugs that selectively inhibit thromboxane synthesis to modify endotoxin shock in conscious rats. 1984 Br. J. Pharmacol. pmid:6375795
Merola AJ et al. Prostaglandin response in the exercise conditioned rat. 1984 Prostaglandins Leukot Med pmid:6377328
D'Angelo A et al. Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. 1984 Eur. J. Clin. Invest. pmid:6428908
Schenkein HA and Rutherford RB Effects of serum on C3b-stimulated release of prostaglandins and thromboxane B2 from human monocytes. 1984 Immunopharmacology pmid:6511367
Fung WP et al. Effect of ethanol on gastric secretion of thromboxane B2. 1984 Med. J. Malaysia pmid:6513851
Hänsch GM et al. Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. 1984 J. Immunol. pmid:6432907
Rachmilewitz D and Karmeli F Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. 1984 Eur. J. Pharmacol. pmid:6152213
Stock JL and Coderre JA Calcitonin enhances production of prostaglandins by stimulated human monocytes. 1984 Prostaglandins pmid:6087420
Yui Y et al. Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. 1984 Circulation pmid:6434196
Vesterqvist O et al. Development of a GC-MS method for quantitation of 2,3-dinor-TxB2 and determinations of the daily urinary excretion rates in healthy humans. 1984 Thromb. Res. pmid:6695361
Davì G et al. Platelet function changes in acute myocardial infarction. 1984 Adv. Exp. Med. Biol. pmid:6695571
Mehta J et al. Thromboxane release in coronary artery disease: spontaneous versus pacing-induced angina. 1984 Am. Heart J. pmid:6695662
Klotz TA et al. Urinary excretion of thromboxane B2 in patients with venous thromboembolic disease. 1984 Chest pmid:6697787
Dembinska-Kieć A et al. Formation of leukotriene C4-like material by rat brain tissue. 1984 Eur. J. Pharmacol. pmid:6426980
Stuart MJ et al. Effects of hyperoxia and hypoxia on vascular prostacyclin formation in vitro. 1984 Pediatrics pmid:6435087
Vergani CG et al. Bile lipid composition and haemostatic variables in a case of high density lipoprotein deficiency (Tangier disease). 1984 Eur. J. Clin. Invest. pmid:6421598
Morrison AR and Crowley JR Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla. 1984 Arch. Biochem. Biophys. pmid:6437329
Oglesby TD and Gorman RR The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. 1984 Biochim. Biophys. Acta pmid:6424715
Marks JG et al. Contact urticaria and airway obstruction from carbonless copy paper. 1984 Aug 24-31 JAMA pmid:6235381
MacNab MW et al. The effects of a new thromboxane synthetase inhibitor, CGS-13080, in man. 1984 Feb-Mar J Clin Pharmacol pmid:6371062
Buchanan MR and Hirsh J Effect of aspirin and salicylate on platelet-vessel wall interactions in rabbits. 1984 Jul-Aug Arteriosclerosis pmid:6380468
Paajanen H et al. Modification of platelet aggregation and thromboxane synthesis by intravascular contrast media. 1984 Jul-Aug Invest Radiol pmid:6434489
De Caterina R et al. Thromboxane-B2 generation during ex-vivo platelet aggregation. 1984 Jul-Sep J. Nucl. Med. Allied Sci. pmid:6530623
Egg D Concentrations of prostaglandins D2, E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 in synovial fluid from patients with inflammatory joint disorders and osteoarthritis. 1984 Mar-Apr Z Rheumatol pmid:6730731
Tanabe M et al. Inhibition of coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion by 2-phenylaminoadenosine (CV-1808) in anesthetized dogs. 1984 May-Jun J. Cardiovasc. Pharmacol. pmid:6202970
Laustiola K et al. Exercise-induced increase in plasma arachidonic acid and thromboxane B2 in healthy men: effect of beta-adrenergic blockade. 1984 May-Jun J. Cardiovasc. Pharmacol. pmid:6202971
Sturm M et al. The measurement of plasma thromboxane B2 and the effect of smoking. 1984 Nov-Dec Clin. Exp. Pharmacol. Physiol. pmid:6536421
Menitove JE et al. Use of prostacyclin to inhibit activation of platelets during preparation of platelet concentrates. 1984 Nov-Dec Transfusion pmid:6390814
Fisher M et al. Selective thromboxane inhibition: a new approach to antiplatelet therapy. 1984 Sep-Oct Stroke pmid:6474531
Uderman HD et al. Thromboxane synthetase inhibitor UK38,485 lowers blood pressure in the adult spontaneously hypertensive rat. 1984 Sep-Oct J. Cardiovasc. Pharmacol. pmid:6209508
Ahlsten G et al. Aggregation of and thromboxane B2 synthesis in platelets from newborn infants of smoking and non-smoking mothers. 1985 Prostaglandins Leukot Med pmid:3863152
Mehta J et al. Increase in human platelet alpha 2-adrenergic receptor affinity for agonist in unstable angina. 1985 J. Lab. Clin. Med. pmid:2866219
Greer IA et al. A comparative study of the effects of adrenoceptor antagonists on platelet aggregation and thromboxane generation. 1985 Thromb. Haemost. pmid:2867620
Yardumian DA et al. Platelet hyperaggregability occurring during prolonged continuous intravenous infusions of prostacyclin analogue ZK 36374. 1985 Br. J. Haematol. pmid:2408653
Patrassi GM et al. Contact phase of coagulation in diabetes mellitus after aspirin administration. 1985 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:2410343
Safai-Kutti S et al. Plasma concentrations of platelet-specific proteins and serum thromboxane B2 production in response to treatment with dipyridamole. A pilot study of 27 post-myocardial infarction patients. 1985 Eur. Heart J. pmid:2412820
Demling RH et al. Early lung dysfunction after major burns: role of edema and vasoactive mediators. 1985 J Trauma pmid:2413227
Myśliwiec M et al. Plasma thromboxane B2 in haemodialysed patients. 1985 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:2414174
Schlondorff D and Satriano JA Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. 1985 Am. J. Physiol. pmid:2579584
Kobayashi H et al. Effects of 6-keto-prostaglandin E1 on ascitic hepatoma-130 in vivo comparison with chemotherapeutic agents. 1985 Prostaglandins pmid:3920729
Ylitalo P et al. Inhibition of prostaglandin synthesis by indomethacin interacts with the antihypertensive effect of atenolol. 1985 Clin. Pharmacol. Ther. pmid:3899459
De Caterina R et al. Low-dose aspirin in patients recovering from myocardial infarction. Evidence for a selective inhibition of thromboxane-related platelet function. 1985 Eur. Heart J. pmid:3930246
Gorczynska E et al. [Effect of various stimulators on cyclooxygenase activity, platelet aggregation and TxB2 synthesis after using a platelet inhibitor (Aspro Clear) in vivo and in vitro]. 1985 Wiad. Lek. pmid:3933184
Berman B et al. Interferon enhancement of HLA-DR antigen expression on epidermal Langerhans cells. 1985 J. Invest. Dermatol. pmid:2578172
Shayevitz JR et al. Inhalation anesthetics augment oxidant-induced pulmonary vasoconstriction: evidence for a membrane effect. 1985 Anesthesiology pmid:3933385
Mehta P et al. Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. 1985 Am J Pediatr Hematol Oncol pmid:2994511
Patrono C et al. Clinical pharmacology of platelet cyclooxygenase inhibition. 1985 Circulation pmid:3933848
VanRollins M et al. Metabolism of 7,10,13,16-docosatetraenoic acid to dihomo-thromboxane, 14-hydroxy-7,10,12-nonadecatrienoic acid and hydroxy fatty acids by human platelets. 1985 Biochim. Biophys. Acta pmid:3918572
Gee MH et al. Eicosanoids, leukocytes and lung injury. 1985 Prog. Clin. Biol. Res. pmid:3934681
Benigni A et al. Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated? 1985 Am. J. Nephrol. pmid:2996352
Leslie JB and Watkins WD Eicosanoids in the central nervous system. 1985 J. Neurosurg. pmid:2997413
Darius H et al. Beneficial effects of a new potent and specific thromboxane receptor antagonist (SQ-29,548) in vitro and in vivo. 1985 J. Pharmacol. Exp. Ther. pmid:2997428
Zavagli G et al. Platelet aggregation and evaluation of the ratio thromboxane B2/6-keto-prostaglandin F1 alpha in the plasma of patients on long term cimetidine treatment. 1985 Prostaglandins Leukot Med pmid:2997804
Sinzinger H Double blind study of the influence of co-dergocrine on platelet parameters in healthy volunteers. 1985 Eur. J. Clin. Pharmacol. pmid:2998802
Schambelan M et al. Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus. 1985 J. Clin. Invest. pmid:3156147
Klotman PE et al. Captopril enhances aminoglycoside nephrotoxicity in potassium-depleted rats. 1985 Kidney Int. pmid:2422431
Pediconi M et al. Effects of acute and chronic ethanol administration on thromboxane and prostacyclin levels and release in rat brain cortex. 1985 Prostaglandins pmid:3901122
Neri Serneri GG et al. Abnormal cardiocoronary thromboxane A2 production in patients with unstable angina. 1985 Am. Heart J. pmid:3984828
Vesterqvist O et al. In vivo production of thromboxane in acute human myocardial infarction: a preliminary study. 1985 Thromb. Res. pmid:3992528
Wirthumer-Hoche C and Sinzinger H [Protein binding of thromboxane--one of the sources of error in thromboxane determination]. 1985 Wien. Klin. Wochenschr. pmid:3993037
Croft KD et al. Onset of changes in phospholipid fatty acid composition and prostaglandin synthesis following dietary manipulation with n-6 and n-3 fatty acids in the rat. 1985 Biochim. Biophys. Acta pmid:3995069
Eldor A et al. Platelet interaction with subendothelial extracellular matrix: platelet-fibrinogen interactions are essential for platelet aggregation but not for the matrix-induced release reaction. 1985 Blood pmid:3995180
Preud'homme Y et al. Metabolism of arachidonic acid in rabbit iris and retina. 1985 Invest. Ophthalmol. Vis. Sci. pmid:3930417
Zahavi J and Zahavi M Enhanced platelet release reaction, shortened platelet survival time and increased platelet aggregation and plasma thromboxane B2 in chronic obstructive arterial disease. 1985 Thromb. Haemost. pmid:3158092
Roy L et al. Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease. 1985 Am. Heart J. pmid:3158183
Pedrinelli R et al. The influence of selective and nonselective prostaglandin inhibition on renin. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159197
Ezra D et al. Effects of platelet-activating factor on coronary hemodynamics and coronary venous plasma levels of TXB2, 6-keto-PGF1 alpha, and leukotriene C4 immunoreactivity in the intact domestic pig heart. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159202
Gensini GF et al. Effects of dipyridamole infusion on local platelet aggregation and local formation of thromboxane A2 in patients with pulmonary hypertension. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159209
De Caterina R et al. Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159210
Rajtar G et al. Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors. 1985 Biochem. Pharmacol. pmid:3918536
Valentovic MA and Lubawy WC Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. 1985 Prostaglandins Leukot Med pmid:3903777
Nigam S et al. The concentrations of 6-keto-PGF1 alpha and TXB2 in plasma samples from patients with benign and malignant tumours of the breast. 1985 Prostaglandins pmid:3839084
Petroni A et al. Differential effects of various vasoactive drugs on basal and stimulated levels of TXB2 and 6-keto-PGF1 alpha in rat brain. 1985 Prostaglandins pmid:3839085
Zipser RD Effects of selective inhibition of thromboxane synthesis on renal function in humans. 1985 Am. J. Physiol. pmid:3839111
Weisman SM et al. Platelet-activating factor is a potent stimulus for renal prostaglandin synthesis: possible significance in unilateral ureteral obstruction. 1985 J. Pharmacol. Exp. Ther. pmid:3862805
Fink MP et al. Low-dose dopamine preserves renal blood flow in endotoxin shocked dogs treated with ibuprofen. 1985 J. Surg. Res. pmid:3839278
Bornman MS et al. Elevated thromboxane B2 levels during erection. 1985 S. Afr. Med. J. pmid:3839322
Steinhauer HB et al. Stimulation of peritoneal synthesis of vasoactive prostaglandins during peritonitis in patients on continuous ambulatory peritoneal dialysis. 1985 Eur. J. Clin. Invest. pmid:3921379
DiMinno G et al. Increased binding of fibrinogen to platelets in diabetes: the role of prostaglandins and thromboxane. 1985 Blood pmid:2981130
Gairola C and Tai HH Selective inhibition of leukotriene B4 biosynthesis in rat pulmonary alveolar macrophages by dietary selenium deficiency. 1985 Biochem. Biophys. Res. Commun. pmid:2998361
Rinaldo JE and Dauber JH Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia. 1985 Circ. Shock pmid:4053294
Leffler CW and Busija DW Prostanoids in cortical subarachnoid cerebrospinal fluid and pial arterial diameter in newborn pigs. 1985 Circ. Res. pmid:4053302
Ment LR et al. Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension. 1985 J. Neurosurg. pmid:4056903
Katoh K et al. [Serial changes in plasma thromboxane and complement in ARDS--effect of the thromboxane synthetase inhibitor]. 1985 Masui pmid:4057547
Purkerson ML et al. Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:3855542
Jackson EK Effects of thromboxane synthase inhibition on vascular responsiveness in the in vivo rat mesentery. 1985 J. Clin. Invest. pmid:4077980
Dempsey RJ et al. Polyamine and prostaglandin markers in focal cerebral ischemia. 1985 Neurosurgery pmid:3864030
Dahl ML and Uotila P Sodium salicylate does not prevent the inhibitory effect of indomethacin on thromboxane formation in human blood ex vivo. 1985 Prostaglandins Leukot Med pmid:3856282
Kääpä P Immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in neonatal hyperbilirubinemia. 1985 Prostaglandins Leukot Med pmid:3856285
Zijlstra FJ and Vincent JE Leukotriene D4 and phospholipase A2 release thromboxane A2 of different origin in the guinea pig lung parenchymal strip. 1985 Prostaglandins Leukot Med pmid:3857642
Salmon JA et al. Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase. 1985 Prostaglandins pmid:2988019
Hutchison AA et al. Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates. 1985 Prostaglandins Leukot Med pmid:3859877