Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hayashi N et al. | Effect of intravenous omega-6 and omega-3 fat emulsions on nitrogen retention and protein kinetics in burned rats. | 1999 | Nutrition | pmid:9990578 |
Bode AP et al. | Activation and adherence of lyophilized human platelets on canine vessel strips in the Baumgartner perfusion chamber. | 1999 | J. Lab. Clin. Med. | pmid:9989772 |
Montuschi P et al. | Anaphylaxis increases 8-iso-prostaglandin F2alpha release from guinea-pig lung in vitro. | 1999 | Eur. J. Pharmacol. | pmid:9988124 |
Gust R et al. | Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:9927374 |
Fredenrich A et al. | Effects of low density and high density lipoproteins isolated from non-insulin dependent diabetic patients on prostaglandin secretion by mouse macrophage cell line P388D1. | 1999 | Atherosclerosis | pmid:9920525 |
MacKay RJ et al. | Effect of a conjugate of polymyxin B-dextran 70 in horses with experimentally induced endotoxemia. | 1999 | Am. J. Vet. Res. | pmid:9918150 |
Huang YS et al. | Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns. | 1998 | Burns | pmid:9915670 |
Holt S et al. | Acute cholestasis-induced renal failure: effects of antioxidants and ligands for the thromboxane A2 receptor. | 1999 | Kidney Int. | pmid:9893136 |
Davì G et al. | In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. | 1999 | Circulation | pmid:9892587 |
González E et al. | Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888203 |
Hoffmann MW et al. | [Long term effects of 50 mg acetylsalicylic acid alone and in combination with dipyridamole on platelet function after coronary bypass surgery]. | 1998 | Z Kardiol | pmid:9885179 |
Shen ZQ et al. | Effects of copper-aspirin complex on platelet aggregation and thrombosis in rabbits and mice. | 1998 | J. Pharm. Pharmacol. | pmid:9877314 |
Guimarães PC et al. | Variations in white blood count, thromboxane B2 levels and hematocrit in chronic venous hypertension. | 1998 May-Jun | Sao Paulo Med J | pmid:9876450 |
Takeuchi K et al. | Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition. 3. Synthesis and biological activities of oxazolecarboxamide-substituted omega-phenyl-omega-(3-pyridyl)alkenoic acid derivatives and related compounds. | 1998 | J. Med. Chem. | pmid:9876106 |
McAdam BF et al. | Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874808 |
Hwang GS et al. | Effects of Brazilin on the phospholipase A2 activity and changes of intracellular free calcium concentration in rat platelets. | 1998 | Arch. Pharm. Res. | pmid:9868555 |
Li HP et al. | [The relationship between the activity of phospholipase A2 and acute hypoxic pulmonary arterial pressure]. | 1997 | Sheng Li Xue Bao | pmid:9863193 |
Hu DH et al. | [Effects of hypoxia and anisodamine on products of TXA2 and PGI2 in cultured intra-pulmonary arteriolar smooth muscle cells]. | 1997 | Sheng Li Xue Bao | pmid:9863190 |
Wu JX et al. | [Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863132 |
Zhang XY and Qian XM | [Clinical study of sudden deafness treated with method of integrated traditional Chinese and Western medicine]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863112 |