Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Capodanno D and Angiolillo DJ | Platelet monitoring for PCI: which test is the one to choose? | 2009 | Hamostaseologie | pmid:19882078 |
| Gao XR et al. | Efficacy of different doses of aspirin in decreasing blood levels of inflammatory markers in patients with cardiovascular metabolic syndrome. | 2009 | J. Pharm. Pharmacol. | pmid:19903376 |
| Zuo Y et al. | Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up. | 2009 | J. Neurol. Sci. | pmid:19801153 |
| Frelinger AL et al. | Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. | 2009 | Circulation | pmid:19996015 |
| Kambara T et al. | Propofol suppresses prostaglandin E(2) production in human peripheral monocytes. | 2009 | Immunopharmacol Immunotoxicol | pmid:19951072 |
| Hu Y et al. | Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. | 2009 | Immunopharmacol Immunotoxicol | pmid:19874221 |
| Li M et al. | Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. | 2009 | J. Vasc. Res. | pmid:19571576 |
| McClelland S et al. | Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse. | 2009 | Atherosclerosis | pmid:18514659 |
| Xu Y et al. | Urocortin promotes the development of vasculitis in a rat model of thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19572944 |
| Zhao L et al. | Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. | 2009 | Br. J. Pharmacol. | pmid:19220291 |
| Shah KB et al. | The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. | 2009 | Hypertension | pmid:19597033 |
| Ulbrich SE et al. | Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. | 2009 | Reproduction | pmid:19470711 |
| Zeng HH et al. | [Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia]. | 2009 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21186611 |
| Santilli F et al. | Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". | 2009 | J. Am. Coll. Cardiol. | pmid:19232899 |
| Lev EI | Aspirin resistance transient laboratory finding or important clinical entity? | 2009 | J. Am. Coll. Cardiol. | pmid:19232900 |
| Bernoud-Hubac N et al. | Low concentrations of reactive gamma-ketoaldehydes prime thromboxane-dependent human platelet aggregation via p38-MAPK activation. | 2009 | Biochim. Biophys. Acta | pmid:19233311 |
| Giraudel JM et al. | Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19161453 |
| Jespersen B et al. | Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo. | 2009 | Nephrol. Dial. Transplant. | pmid:19193738 |
| Chen SS et al. | Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. | 2009 | Diabet. Med. | pmid:19236624 |
| Basselin M et al. | Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. | 2009 | Neuropsychopharmacology | pmid:19145225 |
| Shen H et al. | Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). | 2009 | Am. J. Cardiol. | pmid:19660620 |
| Leoncini G et al. | In retinal vein occlusion platelet response to thrombin is increased. | 2009 | Thromb. Res. | pmid:19660790 |
| Canales A et al. | Platelet aggregation, eicosanoid production and thrombogenic ratio in individuals at high cardiovascular risk consuming meat enriched in walnut paste. A crossover, placebo-controlled study. | 2009 | Br. J. Nutr. | pmid:19068151 |
| Duda MK et al. | Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction. | 2009 | Cardiovasc. Res. | pmid:19015135 |
| Hynninen VV et al. | Voriconazole increases while itraconazole decreases plasma meloxicam concentrations. | 2009 | Antimicrob. Agents Chemother. | pmid:19015346 |
| Kerola M et al. | Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19152549 |
| O'Donnell ME et al. | The effects of cilostazol on exercise-induced ischaemia-reperfusion injury in patients with peripheral arterial disease. | 2009 | Eur J Vasc Endovasc Surg | pmid:19112032 |
| Bailey SR et al. | Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. | 2009 | Vet. Immunol. Immunopathol. | pmid:19091426 |
| Dołegowska B et al. | Platelets arachidonic acid metabolism in patients with essential hypertension. | 2009 | Platelets | pmid:19440924 |
| Ahmad M et al. | Prolonged opportunity for neuroprotection in experimental stroke with selective blockade of cyclooxygenase-2 activity. | 2009 | Brain Res. | pmid:19446533 |
| Mayer K et al. | Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19136374 |
| Schuijt MP et al. | The interaction of ibuprofen and diclofenac with aspirin in healthy volunteers. | 2009 | Br. J. Pharmacol. | pmid:19466986 |
| Eriksson AC et al. | Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study. | 2009 | J Transl Med | pmid:19508722 |
| Csányi G et al. | Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. | 2008 May-Jun | Pharmacol Rep | pmid:18622059 |
| Larson MK et al. | Effects of omega-3 acid ethyl esters and aspirin, alone and in combination, on platelet function in healthy subjects. | 2008 | Thromb. Haemost. | pmid:18841286 |
| Patrignani P et al. | Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study. | 2008 | Pharmacogenet. Genomics | pmid:18551041 |
| Cheuk BL and Cheng SW | Can local secretion of prostaglandin E2, thromboxane B2, and interleukin-6 play a role in ruptured abdominal aortic aneurysm? | 2008 | World J Surg | pmid:17992560 |
| Francois H et al. | A role for the thromboxane receptor in L-NAME hypertension. | 2008 | Am. J. Physiol. Renal Physiol. | pmid:18684890 |
| Guthikonda S et al. | Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy. | 2008 | Thromb. Haemost. | pmid:18612542 |
| Kaehler S et al. | S-ibuprofen effectively inhibits thromboxane B2 levels and platelet function in an experimental model of lipopolysaccharide-stimulated and non-stimulated whole blood. | 2008 | Pharmacology | pmid:18043009 |
| Elander N et al. | Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18485889 |
| Abdelwhab S and Elshinnawy S | Pulmonary hypertension in chronic renal failure patients. | 2008 | Am. J. Nephrol. | pmid:18635926 |
| Graff J et al. | Significant effects of tipranavir on platelet aggregation and thromboxane B2 formation in vitro and in vivo. | 2008 | J. Antimicrob. Chemother. | pmid:18156609 |
| Delgado-Lista J et al. | Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. | 2008 | Am. J. Clin. Nutr. | pmid:18258620 |
| Tanen DA et al. | Comparison of oral aspirin versus topical applied methyl salicylate for platelet inhibition. | 2008 | Ann Pharmacother | pmid:18698012 |
| Hinz B et al. | Impact of naproxen sodium at over-the-counter doses on cyclooxygenase isoforms in human volunteers. | 2008 | Int J Clin Pharmacol Ther | pmid:18397691 |
| Bruce EC et al. | Platelet thromboxane A2 secretion in patients with major depression responsive to electroconvulsive therapy. | 2008 | Psychosom Med | pmid:18378867 |
| Wooten JG et al. | Cyclooxygenase expression and prostanoid production in pyloric and duodenal mucosae in dogs after administration of nonsteroidal anti-inflammatory drugs. | 2008 | Am. J. Vet. Res. | pmid:18380576 |
| Eikelboom JW et al. | Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. | 2008 | Circulation | pmid:18838564 |
| Banting A et al. | Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. | 2008 | Vet. Rec. | pmid:18953074 |