Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hsu MF et al. | Blockade of cytosolic phospholipase A(2) and 5-lipoxygenase activation in neutrophils by a natural isoflavanquinone abruquinone A. | 2008 | Eur. J. Pharmacol. | pmid:18834875 |
| Kaneko I et al. | Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18190789 |
| Parsons JP et al. | Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. | 2008 | J Asthma | pmid:18569228 |
| Natarajan G et al. | Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. | 2008 | Am J Perinatol | pmid:18726836 |
| Santilli F et al. | Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. | 2008 | Blood | pmid:18541722 |
| Mitsopoulos P et al. | Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. | 2008 | Int J Pharm | pmid:18694812 |
| Yokoyama Y et al. | Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. | 2008 | Shock | pmid:17885643 |
| Meen O et al. | No case of COX-1-related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography. | 2008 | Scand. J. Clin. Lab. Invest. | pmid:17934975 |
| Zhao S et al. | Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. | 2008 | Placenta | pmid:17936899 |
| Heistein LC et al. | Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms. | 2008 | Pediatr Cardiol | pmid:17896127 |
| Lessa A et al. | The effect of pentoxifylline on the pulmonary response to high tidal volume ventilation in rats. | 2008 | Pulm Pharmacol Ther | pmid:17251044 |
| Aslam R et al. | Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18215184 |
| Toscano CD et al. | NMDA-induced seizure intensity is enhanced in COX-2 deficient mice. | 2008 | Neurotoxicology | pmid:18834901 |
| Lee CR et al. | Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. | 2008 | Clin. Pharmacol. Ther. | pmid:17495879 |
| Awad H et al. | Intracellular and extracellular expression of the major inducible 70kDa heat shock protein in experimental ischemia-reperfusion injury of the spinal cord. | 2008 | Exp. Neurol. | pmid:18511046 |
| Basselin M et al. | Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. | 2008 | Neurochem. Res. | pmid:18461450 |
| Dobaczewski M et al. | Targeting the urine and plasma determinants of thromboxane A2 metabolism in detection of aspirin effectiveness. | 2008 | Blood Coagul. Fibrinolysis | pmid:18600093 |
| Rossoni G et al. | Combined simvastatin-manidipine protect against ischemia-reperfusion injury in isolated hearts from normocholesterolemic rats. | 2008 | Eur. J. Pharmacol. | pmid:18442813 |
| Yan Q et al. | Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production. | 2008 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:18579648 |
| Gao L et al. | [Effects of supplementing qi and activating blood circulation method on platelet aggregation rate, adhesion rate and thromboxane B2 level in patients with stable angina pectoris and intolerable to aspirin]. | 2008 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:18543479 |
| Nocun M et al. | French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats. | 2008 | Biomed. Pharmacother. | pmid:17698319 |
| Park MK et al. | Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. | 2008 | Phytother Res | pmid:17724769 |
| Rao CV et al. | Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. | 2008 | Int. J. Oncol. | pmid:18813794 |
| Rajec J et al. | Biochemical evaluation of the antiplatelet effect of aspirin in patients at different levels of cardiovascular risk. | 2008 | Bratisl Lek Listy | pmid:18814431 |
| Helgason CM et al. | Platelet aggregation and recruitment with aspirin-clopidogrel therapy. | 2008 | Cerebrovasc. Dis. | pmid:18349532 |
| Momen A et al. | Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18326807 |
| Skoglund C et al. | C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. | 2008 | Immunol. Cell Biol. | pmid:18332893 |
| Menzies D et al. | Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. | 2008 | J. Allergy Clin. Immunol. | pmid:18313127 |
| Geske FJ et al. | AspirinWorks: a new immunologic diagnostic test for monitoring aspirin effect. | 2008 | Mol Diagn Ther | pmid:18288882 |
| Selg E et al. | Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18294831 |
| Basselin M et al. | Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain. | 2008 | Neurochem. Res. | pmid:18302021 |
| Signore C et al. | Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. | 2008 | Alcohol. Clin. Exp. Res. | pmid:18715278 |
| Roethig HJ et al. | A 12-month, randomized, controlled study to evaluate exposure and cardiovascular risk factors in adult smokers switching from conventional cigarettes to a second-generation electrically heated cigarette smoking system. | 2008 | J Clin Pharmacol | pmid:18319361 |
| Al-Salam Z et al. | The effect of dobutamine on platelet aggregatory function in newborn piglets with hypoxia and reoxygenation. | 2008 | Shock | pmid:18323735 |
| Park JW et al. | 15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization. | 2008 | Arch. Pharm. Res. | pmid:18277607 |
| Schwartz JI et al. | Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. | 2008 | J Clin Pharmacol | pmid:18434566 |
| Cui J et al. | Cyclooxygenase inhibition attenuates sympathetic responses to muscle stretch in humans. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18441194 |
| Hasan J et al. | Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18096423 |
| Karon BS et al. | Aspirin responsiveness in healthy volunteers measured with multiple assay platforms. | 2008 | Clin. Chem. | pmid:18420732 |
| Ruan KH et al. | An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector. | 2008 | FEBS J. | pmid:19021758 |
| Jiang H et al. | The midnight-noon ebb-flow point selection for 30 cases of acute ischemic cerebrovascular diseases. | 2008 | J Tradit Chin Med | pmid:19004202 |
| Otani Y et al. | Effects of the COX-2 inhibitor FK3311 on ischemia - reperfusion injury in the rat lung. | 2007 May-Jun | J Invest Surg | pmid:17613692 |
| Jiang J et al. | Endothelin-1 blockade prevents COX2 induction and TXA2 production in the fructose hypertensive rat. | 2007 Mar-Apr | Can. J. Physiol. Pharmacol. | pmid:17612651 |
| Csanyi G et al. | Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. | 2007 Jul-Aug | Pharmacol Rep | pmid:17901574 |
| Komers R et al. | Cyclo-oxygenase-2 inhibition attenuates the progression of nephropathy in uninephrectomized diabetic rats. | 2007 Jan-Feb | Clin. Exp. Pharmacol. Physiol. | pmid:17201733 |
| González-Correa JA et al. | Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes. | 2007 Aug-Sep | Vascul. Pharmacol. | pmid:17581795 |
| Coppinger JA et al. | Moderation of the platelet releasate response by aspirin. | 2007 | Blood | pmid:17303692 |
| Guthikonda S et al. | Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. | 2007 | J. Thromb. Haemost. | pmid:17319904 |
| Maksimova MIu et al. | [Hemorheology and homeostasis in the most acute stage of lacunar stroke]. | 2007 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:18427452 |
| Yousefipour Z et al. | Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17494862 |