Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Steib CJ et al. | Intraperitoneal LPS amplifies portal hypertension in rat liver fibrosis. | 2010 | Lab. Invest. | pmid:20212458 |
| Dragani A et al. | The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy. | 2010 | Blood | pmid:19887674 |
| Kienzler JL et al. | Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers. | 2010 | J Clin Pharmacol | pmid:19841157 |
| Würtz M et al. | The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease. | 2010 | Heart | pmid:19910291 |
| Koeberle A et al. | The molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. | 2010 | J. Pharmacol. Exp. Ther. | pmid:19934399 |
| Armstrong PC et al. | Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy. | 2010 | J. Thromb. Haemost. | pmid:19995405 |
| Nørregaard R et al. | Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20147610 |
| Oldenhof J et al. | Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2. | 2010 | Curr Med Res Opin | pmid:20429831 |
| Dharmasaroja PA and Sae-Lim S | Effects of different doses, enteric-coated preparation of aspirin, and sex on urinary 11-dehydrothromboxane B2 in healthy volunteers. | 2010 | Blood Coagul. Fibrinolysis | pmid:20689403 |
| Milara J et al. | Cigarette smoke exposure up-regulates endothelin receptor B in human pulmonary artery endothelial cells: molecular and functional consequences. | 2010 | Br. J. Pharmacol. | pmid:20698855 |
| Anauate MC et al. | Effect of isolated fractions of Harpagophytum procumbens D.C. (devil's claw) on COX-1, COX-2 activity and nitric oxide production on whole-blood assay. | 2010 | Phytother Res | pmid:20812280 |
| Yassine HN et al. | Clinical determinants of aspirin resistance in diabetes. | 2010 | Diabetes Res. Clin. Pract. | pmid:20719400 |
| Würtz M et al. | Patients with previous definite stent thrombosis have a reduced antiplatelet effect of aspirin and a larger fraction of immature platelets. | 2010 | JACC Cardiovasc Interv | pmid:20723855 |
| Kim SY et al. | Platelet anti-aggregation activities of compounds from Cinnamomum cassia. | 2010 | J Med Food | pmid:20828311 |
| Bao YM et al. | [Effect of precondition with GBE50 and Salviae miltionrrhizae on cycloxygenase-2 and its downstream effectors contents in ischemia/reperfusion myocardium]. | 2010 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:21066890 |
| De la Cruz JP et al. | Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood. | 2010 | Anesth. Analg. | pmid:21048099 |
| Wang BZ et al. | [Association of the Pro1770Leu polymorphism in CYP5A1 gene with myocardial infarction in Uigur population of Xinjiang]. | 2010 | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | pmid:20931532 |
| Wang BZ et al. | [Association of Rs10487667 genetic polymorphism of thromboxane synthase with myocardial infarction in Uigur population of Xinjiang]. | 2010 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:21215134 |
| Ge Y et al. | [Effect of ulinastatin on thromboxane Bâ‚‚ and deep vein thrombosis in elderly patients after hip joint replacement]. | 2010 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:21200097 |
| Santilli F et al. | Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus. | 2010 | J. Thromb. Haemost. | pmid:20088941 |