Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Buchanan MR et al. Aspirin inhibits platelet function independent of the acetylation of cyclo-oxygenase. 1982 Thromb. Res. pmid:7071811
Tremoli E et al. Metformin reduces platelet hypersensitivity in hypercholesterolemic rabbits. 1982 Atherosclerosis pmid:7073794
Tanabe M et al. Coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion in anaesthetised dogs. 1982 Cardiovasc. Res. pmid:7074670
Peterson MB et al. Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion. 1982 Am. J. Physiol. pmid:7051860
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
Numano F et al. Effects of thromboxane A2 injection on the rabbit coronary artery. II. The production of infarcts in cholesterol-fed animals. 1982 Exp. Mol. Pathol. pmid:6956517
Grundfest CC et al. Acrolein: a potent modulator of lung macrophage arachidonic acid metabolism. 1982 Biochim. Biophys. Acta pmid:6814492
Aharony D et al. Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid. 1982 Biochim. Biophys. Acta pmid:6814496
Utsunomiya T et al. Modification of inflammatory response to aspiration with ibuprofen. 1982 Am. J. Physiol. pmid:6756172
Tooke JE et al. Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man. 1982 Prostaglandins Leukot Med pmid:6757966
Herman CA et al. Prostaglandins of the one, two, and three series affect blood pressure in the american bullfrog, Rana catesbeiana. 1982 Gen. Comp. Endocrinol. pmid:6761235
Davì G et al. Thromboxane B2 formation and platelet sensitivity to prostacyclin in insulin-dependent and insulin-independent diabetics. 1982 Thromb. Res. pmid:6761893
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
Hornych A et al. Radioimmunoassay measurement of thromboxane B2 in human plasma and urine. 1982 Prostaglandins Leukot Med pmid:6954551
Mest HJ et al. Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. 1982 Prostaglandins Leukot Med pmid:6955811
Karmali RA et al. Macrophage production of prostaglandins: effects of fetal calf serum and diazepam. Use of an improved method for extracting 6-keto-PGF1 alpha. 1982 Prostaglandins Leukot Med pmid:6955812
Mehta J et al. Severe intracoronary thromboxane release preceding acute coronary artery occlusion. 1982 Prostaglandins Leukot Med pmid:6955814
Jaweed MM et al. Changes in thromboxane B2 and 6-keto-PGF1 alpha after direct electrical stimulation of the denervated rat gastrocnemius1,2. 1982 Prostaglandins Leukot Med pmid:6956927
Taube C et al. Enhanced thromboxane production in the aorta of spontaneously hypertensive rats in vitro. 1982 Prostaglandins Leukot Med pmid:6960370
Castaldi PA et al. Evidence for a platelet membrane defect in the myeloproliferative syndromes. 1982 Thromb. Res. pmid:6960545
de Boer AC et al. Platelet release and thromboxane synthesis in symptomatic coronary artery disease. 1982 Circulation pmid:6212161
Mari D et al. Coagulation and platelet activation after retinal vein occlusions. 1982 Haemostasis pmid:6215293
de Clerck F et al. Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist. 1982 Agents Actions pmid:6215842
Mehta J and Mehta P Effects of propranolol therapy on platelet release and prostaglandin generation in patients with coronary heart disease. 1982 Circulation pmid:6216027
Mehta P et al. Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma. 1982 Prostaglandins Leukot Med pmid:6217465
Havill AM et al. alpha-Naphthylthiourea produces dose-dependent lung vascular injury in sheep. 1982 Am. J. Physiol. pmid:6812437
Preston FE et al. Low-dose aspirin inhibits platelet and venous cyclo-oxygenase in man. 1982 Thromb. Res. pmid:6815823
Burch RM and Halushka PV Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. 1982 Am. J. Physiol. pmid:6816073
Steel LK and Catravas GN Radiation-induced changes in production of prostaglandins F2 alpha, E, and thromboxane B2 in guinea pig parenchymal lung tissues. 1982 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:6818175
Srivastava KC and Awasthi KK A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. 1982 Prostaglandins Leukot Med pmid:6818563
Kelley VE et al. Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus. 1982 Clin. Immunol. Immunopathol. pmid:6819912
Jackson CA et al. Relationship between platelet aggregation, thromboxane synthesis and albumin concentration in nephrotic syndrome. 1982 Br. J. Haematol. pmid:6810912
Robinson C et al. Thromboxane B2 uptake and metabolism in isolated perfused lung. Identification and comparison with prostaglandin F2 alpha. 1982 Biochim. Biophys. Acta pmid:6751406
Schafer AI et al. Platelet lipoxygenase-dependent oxygen burst. Evidence for differential activation of lipoxygenase in intact and disrupted human platelets. 1982 Biochim. Biophys. Acta pmid:6812645
Uyama O et al. Plasma concentrations of 6-keto-prostaglandin F1 alpha in patients with hypertension, cerebrovascular disease or Takayasu's arteritis. 1982 Jan 1-15 Thromb. Res. pmid:6121391
Sakai K et al. Roles of endogenous prostacyclin and thromboxane A2 in the ischemic canine heart. 1982 Jan-Feb J. Cardiovasc. Pharmacol. pmid:6176788
Giannessi D et al. Methodological assessment and applications of a radioimmunoassay for thromboxane (TxB2) to measurement of TxB2 release by platelets. 1982 Jan-Mar J. Nucl. Med. Allied Sci. pmid:7108634
Shohami E et al. The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain. 1982 Jul-Aug Stroke pmid:6896589
Mest HJ et al. [Effect of stress on blood level of prostaglandins in students during exams]. 1982 May-Jun Farmakol Toksikol pmid:7095121
Drake TS et al. Peritoneal fluid prostanoids in unexplained infertility. 1983 Am. J. Obstet. Gynecol. pmid:6614085
Stenson WF and Lobos E Inhibition of platelet thromboxane synthetase by sulfasalazine. 1983 Biochem. Pharmacol. pmid:6135423
Chang J et al. Effects of thiazinamium chloride, promethazine and chlorpromazine on thromboxane B2 synthesis, phagocytosis and respiratory burst by rat alveolar macrophages. 1983 Biochem. Pharmacol. pmid:6138040
McManus LM et al. Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. 1983 Immunopharmacology pmid:6832960
Martin JL et al. Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. 1983 J. Am. Coll. Cardiol. pmid:6833660
Ferraris VA and Swanson E Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. 1983 Surg Gynecol Obstet pmid:6836459
Kangasaho M et al. Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6303086
Samuelsson B From studies of biochemical mechanism to novel biological mediators: prostaglandin endoperoxides, thromboxanes, and leukotrienes. Nobel Lecture, 8 December 1982. 1983 Biosci. Rep. pmid:6315101
Lismonde M et al. [The presence of 6-oxo-PGF1alpha and thromboxane B2 in peritoneal exudates released by iota-carrageenan in the rat]. 1983 Arch. Int. Physiol. Biochim. pmid:6198994
Gorman RR et al. Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate. 1983 Prostaglandins pmid:6316421
Bloch MH et al. Prostaglandin production by the pregnant and non-pregnant rabbit uterus. 1983 Prostaglandins pmid:6415760
Mest HJ et al. The influence of linseed oil diet on fatty acid pattern in phospholipids and thromboxane formation in platelets in man. 1983 Klin. Wochenschr. pmid:6341702
Hartung HP et al. Stimulation of prostaglandin E and thromboxane synthesis in macrophages by purified C3b. 1983 J. Immunol. pmid:6343486
Deckmyn H et al. Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. 1983 Thromb. Res. pmid:6344317
Ylikorkala O and Viinikka L Prostaglandins and endometriosis. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344540
Ylikorkala O Prostacyclin and thromboxane during human pregnancy. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344543
Qvist R and Larkins RG Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects. 1983 Diabetes pmid:6345241
Newman JH et al. Effects of 100% oxygen on lung vascular function in awake sheep. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6345493
Eldor A et al. Effects of dipyrone on prostaglandin production by human platelets and cultured bovine aortic endothelial cells. 1983 Thromb. Haemost. pmid:6346571
Sheng WY et al. Kinetic comparison and regulation of the cascade of microsomal enzymes involved in renal arachidonate and endoperoxide metabolism. 1983 J. Biol. Chem. pmid:6401732
Buchanan MR et al. The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. 1983 Thromb. Res. pmid:6221436
Yamamoto S et al. Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221523
Weerasekera DA et al. Chemiluminescence immunoassay of thromboxane B2. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221524
Ito T et al. Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221531
FitzGerald GA et al. Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221534
van der Giessen WJ et al. Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221546
Nuotto E et al. Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man. 1983 Eur. J. Clin. Pharmacol. pmid:6628518
Bach MK et al. In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221551
Grose JH et al. Imbalanced prostacyclin and thromboxane A2 production in essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221555
Hornych A et al. Thromboxane B2 in borderline and essential hypertension. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221556
Kiff PS et al. Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. 1983 Br J Clin Pharmacol pmid:6681708
Abiko Y et al. The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans. 1983 FEBS Lett. pmid:6403385
Gordon PR et al. Platelet arachidonate metabolism and platelet function in zinc-deficient rats. 1983 J. Nutr. pmid:6403678
Okegawa T et al. Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. 1983 J. Pharmacol. Exp. Ther. pmid:6403696
Wallis RB Mechanisms of action of sulphinpyrazone. 1983 Thromb. Res. Suppl. pmid:6415857
Di Minno G et al. Monitoring the entry of new platelets into the circulation after ingestion of aspirin. 1983 Blood pmid:6404326
Miller JB et al. Alterations in plasma and tissue prostaglandin levels in rabbits during luteal regression. 1983 Biol. Reprod. pmid:6688954
Davì G et al. The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects. 1983 Thromb. Haemost. pmid:6417815
Muccitelli RM et al. Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. 1983 Prostaglandins pmid:6689082
Gerozissis K and Dray F In-vitro prostanoid production by the rat vas deferens. 1983 J. Reprod. Fertil. pmid:6572721
Dale J et al. The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. 1983 Thromb. Haemost. pmid:6689091
Schleimer RP et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. 1983 J. Clin. Invest. pmid:6134755
Liu J [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. 1983 Zhonghua Yi Xue Za Zhi pmid:6418338
Aehringhaus U et al. Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. 1983 Br. J. Pharmacol. pmid:6689134
Kurata M [Relation between mouse peritoneal macrophage functions and prostaglandins]. 1983 Rinsho Byori pmid:6689184
Maguire ED and Wallis RB In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. 1983 Thromb. Res. pmid:6689221
McDonald JW and Ali M Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. 1983 Prostaglandins Leukot Med pmid:6419234
Zijlstra FJ and Vincent JE Comparison of the determination of thromboxane A2 by bioassay on the rabbit mesenteric artery and in the form of TxB2 by radioimmunoassay. 1983 J Pharmacol Methods pmid:6632924
Bryant RW and Hwang DH Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. 1983 Prostaglandins pmid:6419285
Wilson L Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. 1983 Prostaglandins pmid:6635211
Sanders TA and Hochland MC A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. 1983 Br. J. Nutr. pmid:6639916
Chong KP et al. Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. 1983 Prostaglandins pmid:6419286
Hartung HP et al. Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. 1983 J. Immunol. pmid:6600482
Sautebin L et al. Preferential utilization of endogenous arachidonate by cyclo-oxygenase in incubations of human platelets. 1983 FEBS Lett. pmid:6407867
Zipser RD et al. Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. 1983 Gastroenterology pmid:6572162
Schenkelaars EJ and Bonta IL Effect of leukotriene C4 on the release of secretory products by elicited populations of rat peritoneal macrophages. 1983 Eur. J. Pharmacol. pmid:6572592
Rocklin RE et al. Augmentation of prostaglandin and thromboxane production in vitro by monocytes exposed to histamine-induced suppressor factor (HSF). 1983 Cell. Immunol. pmid:6573232
Ouwendijk RJ et al. Raised plasma thromboxane B2 levels in alcoholic liver disease. 1983 Prostaglandins Leukot Med pmid:6573682
Hornych A et al. Thromboxane B2 in borderline and essential hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6573683
Flynn JT et al. Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. 1983 Prostaglandins Leukot Med pmid:6573688
Gimenez T et al. Fetal-maternal secretion of prostaglandins in the cow. 1983 Prostaglandins pmid:6576447