MeSH term | MeSH ID | Detail |
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Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sheehan DV et al. | Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. | 1984 | J Clin Psychopharmacol | pmid:6142907 |
Barnett AH et al. | Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes. | 1984 | Lancet | pmid:6145027 |
Schenkelaars EJ and Bonta IL | Beta 2-adrenoceptor agonists reverse the leukotriene C4-induced release response of macrophages. | 1984 | Eur. J. Pharmacol. | pmid:6151905 |
Giani E et al. | Sex differences in platelet thromboxane and arterial prostacyclin production in control and n-6 fatty acid supplemented rats. | 1984 | Prostaglandins | pmid:6441187 |
Irvine RF et al. | One-dimensional thin-layer chromatographic separation of the lipids involved in arachidonic acid metabolism. | 1984 | J Pharmacol Methods | pmid:6443136 |
Rainsford KD et al. | Comparative effects of some non-steroidal anti-inflammatory drugs on the ultrastructural integrity and prostaglandin levels in the rat gastric mucosa: relationship to drug uptake. | 1984 | Scand. J. Gastroenterol. Suppl. | pmid:6443622 |
Patrignani P et al. | Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism. | 1984 | J. Pharmacol. Exp. Ther. | pmid:6537977 |
Teng CM et al. | Biphasic effect on platelet aggregation by phospholipase a purified from Vipera russellii snake venom. | 1984 | Biochim. Biophys. Acta | pmid:6426517 |
Vesterqvist O and Gréen K | Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions. | 1984 | Prostaglandins | pmid:6539491 |
Hsueh W et al. | Identification of C3b as the major serum protein that stimulates prostaglandin and thromboxane synthesis by macrophages. | 1984 | Prostaglandins | pmid:6240667 |
McCluskey ER et al. | In vivo inhibition of thromboxane synthetase in infarcted canine myocardium. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6539597 |
Chan PK and Gentry PA | Inhibition of bovine platelet function by T-2 toxin, HT-2 toxin, diacetoxyscirpenol and deoxynivalenol. | 1984 | Food Chem. Toxicol. | pmid:6540739 |
Moufarrij NA et al. | Thromboxane synthetase inhibition in acute focal cerebral ischemia in cats. | 1984 | J. Neurosurg. | pmid:6542131 |
Hock CE and Lefer AM | Beneficial effect of a thromboxane synthetase inhibitor in traumatic shock. | 1984 | Circ. Shock | pmid:6542462 |
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De Clerck F et al. | Platelet-vessel wall interactions in hemostasis: implication of 5-hydroxytryptamine. | 1984 | Agents Actions | pmid:6543415 |
Menys VC and Davies JA | Thromboxane-mediated activation of platelets and enhancement of platelet uptake onto collagen-coated glass or deendothelialized rabbit aorta. Comparative effects of a thromboxane antagonist (EPO45) and a thromboxane synthetase inhibitor (dazoxiben). | 1984 | Lab. Invest. | pmid:6546403 |
Brown CG and Poyser NL | Studies on the control of prostaglandin production by the hypothalamus in relation to LH release in the rat. | 1984 | J. Endocrinol. | pmid:6593408 |
Romero SD et al. | Measurement of prostaglandins in the cerebrospinal fluid in cat, dog, and man. | 1984 | J. Neurochem. | pmid:6593432 |
Croft KD et al. | Dietary modification of fatty acid and prostaglandin synthesis in the rat. Effect of variations in the level of dietary fat. | 1984 | Biochim. Biophys. Acta | pmid:6548159 |
Wada H et al. | Effect of TEI-4120 (3-benzoyl-N-beta-ethoxyisopropyl-2-methlindole) on carrageenan induced disseminated intravascular coagulation (DIC) in rats. | 1984 | J. Pharmacobio-dyn. | pmid:6548260 |
Johnston C et al. | Prostacyclin and thromboxane in non-insulin dependent diabetes: the chlorpropamide alcohol flush reaction revisited. | 1984 | Clin. Sci. | pmid:6548428 |
Nicod P et al. | Acute systemic and coronary hemodynamic and serologic responses to cigarette smoking in long-term smokers with atherosclerotic coronary artery disease. | 1984 | J. Am. Coll. Cardiol. | pmid:6548482 |
Okazaki K et al. | [Measurement of prostaglandins in human bile juice]. | 1984 | Nihon Shokakibyo Gakkai Zasshi | pmid:6549033 |
Garcia-Szabo RR et al. | Comparison of alpha- and gamma-thrombin on lung fluid balance in anesthetized sheep. | 1984 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6549181 |
Takeda H et al. | [Comparison of centrifugal pump (bio pump) with roller pump: clinical study]. | 1984 | Kyobu Geka | pmid:6549344 |
Welton AF et al. | Ro 22-3747: a new antiallergic agent for the treatment of immediate hypersensitivity diseases. | 1984 | J. Pharmacol. Exp. Ther. | pmid:6198511 |
Chen LS et al. | Plasma concentrations of 6-keto-prostaglandin F1 alpha, thromboxane B2 and platelet aggregation in patients with essential hypertension. | 1984 | Jpn Heart J | pmid:6549401 |
Ishihara Y et al. | [Cigarette smoking and lung metabolism--effect of cigarette smoking on blood levels of 6-keto PGF1 alpha, thromboxane B2 and lipoperoxide in healthy volunteers]. | 1984 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:6549510 |
Watanabe J et al. | Effect of vitamin E on platelet aggregation in diabetes mellitus. | 1984 | Thromb. Haemost. | pmid:6495252 |
Stahl RA et al. | Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. | 1984 | Am. J. Physiol. | pmid:6507633 |
Kääpä P et al. | Thromboxane B2 production by fetal and neonatal platelets: effect of idiopathic respiratory distress syndrome and birth asphyxia. | 1984 | Pediatr. Res. | pmid:6472947 |
Gross S and Worthington-White DA | The effects of PGF2 alpha, PGI2, and TxB2 on human CFU-C in healthy and leukemic patients. | 1984 | Am. J. Hematol. | pmid:6372442 |
Runkle B et al. | Cardiovascular changes in group B streptococcal sepsis in the piglet: response to indomethacin and relationship to prostacyclin and thromboxane A2. | 1984 | Pediatr. Res. | pmid:6384909 |
Ishii H et al. | The effect of plasma on platelet function in hypercholesterolemic rabbits and the changes in fatty acid composition of the plasma. | 1984 | Thromb. Res. | pmid:6234679 |
Stegmeier K et al. | The pharmacological profile of the thromboxane A2 antagonist BM 13.177. A new anti-platelet and anti-thrombotic drug. | 1984 | Thromb. Res. | pmid:6385334 |
Ritter JM | Prostanoid synthesis by aortic rings in human blood: selective increase of prostacyclin mediated by a serum factor. | 1984 | Br. J. Pharmacol. | pmid:6386089 |
Schneidkraut MJ et al. | Thromboxane and prostacyclin synthesis following whole body irradiation in rats. | 1984 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6386769 |
D'Angelo A et al. | Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. | 1984 | Eur. J. Clin. Invest. | pmid:6428908 |
Puustinen T et al. | Glucocorticoids do not decrease thromboxane and prostacyclin levels in human blood. | 1984 | Prostaglandins Leukot Med | pmid:6387721 |
Del Maschio A et al. | Inhibition of human platelet cyclo-oxygenase activity by sulfinpyrazone and three of its metabolites. | 1984 | Eur. J. Pharmacol. | pmid:6432556 |
Essien EM et al. | Blood changes and enhanced thromboxane and 6-keto prostaglandin F1 alpha production in experimental acute Plasmodium bergei infection in hamsters. | 1984 | Thromb. Haemost. | pmid:6388013 |
Mäkäräinen L and Ylikorkala O | Amniotic fluid 6-keto-prostaglandin F1 alpha and thromboxane B2 during labor. | 1984 | Am. J. Obstet. Gynecol. | pmid:6388335 |
Baughman RP et al. | Prostaglandins and thromboxanes in the bronchoalveolar lavage fluid: possible immunoregulation in sarcoidosis. | 1984 | Am. Rev. Respir. Dis. | pmid:6388445 |
DiSesa VJ et al. | Disadvantages of prostacyclin infusion during cardiopulmonary bypass: a double-blind study of 50 patients having coronary revascularization. | 1984 | Ann. Thorac. Surg. | pmid:6388516 |
Takeda H et al. | [Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation]. | 1984 | Kyobu Geka | pmid:6389949 |
Jackson EK et al. | Attenuation of noradrenergic neurotransmission by the thromboxane synthetase inhibitor, UK 38,485. | 1984 | Life Sci. | pmid:6330486 |
Uotila P et al. | Prostanoids and hemodynamics in man before and during cardiopulmonary bypass. | 1984 | Prostaglandins | pmid:6335260 |
Uehara Y et al. | [A solid phase direct radioimmunoassay for urinary thromboxane B2 and its clinical application]. | 1984 | Nihon Jinzo Gakkai Shi | pmid:6527429 |
Wang JP et al. | Antiplatelet effect of capsaicin. | 1984 | Thromb. Res. | pmid:6528310 |
Kawai C | New horizons in cardiology. | 1984 | Int. J. Cardiol. | pmid:6334040 |
Sedor JR et al. | Effects of sulindac and indomethacin on renal prostaglandin synthesis. | 1984 | Clin. Pharmacol. Ther. | pmid:6428794 |
Hänsch GM et al. | Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. | 1984 | J. Immunol. | pmid:6432907 |
McGoon MD and Vanhoutte PM | Aggregating platelets contract isolated canine pulmonary arteries by releasing 5-hydroxytryptamine. | 1984 | J. Clin. Invest. | pmid:6470141 |
Huang HC | Release of slow reacting substance from the guinea-pig lung by phospholipases A2 of Vipera russelli snake venom. | 1984 | Toxicon | pmid:6206608 |
Brunner D et al. | Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus. | 1984 | Clin Ther | pmid:6206948 |
Gragnoli G et al. | [Effects of ticlopidine on the plasma levels of beta-thromboglobulin and thromboxane B2 in types 1 and 2 diabetics]. | 1984 | Minerva Med. | pmid:6207465 |
Rachmilewitz D and Karmeli F | Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. | 1984 | Eur. J. Pharmacol. | pmid:6152213 |
De Caterina R et al. | Inhibition of platelet function by injectable isosorbide dinitrate. | 1984 | Am. J. Cardiol. | pmid:6428211 |
Stock JL and Coderre JA | Calcitonin enhances production of prostaglandins by stimulated human monocytes. | 1984 | Prostaglandins | pmid:6087420 |
Yui Y et al. | Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. | 1984 | Circulation | pmid:6434196 |
Lee EC et al. | Functional responses of tumor cells to phorbol esters: role for prostaglandins. | 1984 | Oncology | pmid:6587276 |
Jackson CA et al. | Near-normal glycaemic control does not correct abnormal platelet reactivity in diabetes mellitus. | 1984 | Clin. Sci. | pmid:6434224 |
Coker SJ and Parratt JR | The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds. | 1984 | J. Mol. Cell. Cardiol. | pmid:6366241 |
Alster P and Wennmalm A | Effect of nicotine on the formation of prostacyclin-like activity and thromboxane in rabbit aorta and platelets. | 1984 | Br. J. Pharmacol. | pmid:6367870 |
Dembinska-Kieć A et al. | Formation of leukotriene C4-like material by rat brain tissue. | 1984 | Eur. J. Pharmacol. | pmid:6426980 |
Stuart MJ et al. | Effects of hyperoxia and hypoxia on vascular prostacyclin formation in vitro. | 1984 | Pediatrics | pmid:6435087 |
Higashihara M et al. | Interaction of Solanum tuberosum agglutinin with human platelets. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6732807 |
Miyazaki H et al. | Microdetermination of prostaglandins and thromboxane B2 by capillary gas chromatography and negative ion chemical ionization mass spectrometry. | 1984 | J. Chromatogr. | pmid:6736155 |
Kelton JG et al. | A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation. | 1984 | Thromb. Res. | pmid:6740573 |
Ylikorkala O et al. | Peritoneal fluid prostaglandins in endometriosis, tubal disorders, and unexplained infertility. | 1984 | Obstet Gynecol | pmid:6232475 |
Schultze G et al. | Effect of cyclosporine on the generation of prostanoids by cultured peripheral lymphocytes. | 1984 | Transplant. Proc. | pmid:6592863 |
Worthington RE and Fuller GC | Dibutyryl cyclic guanosine monophosphate elevates bovine endothelial cell thromboxane production without affecting prostacyclin metabolism. | 1984 | Thromb. Res. | pmid:6322377 |
Morrison AR and Crowley JR | Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla. | 1984 | Arch. Biochem. Biophys. | pmid:6437329 |
Foegh ML et al. | Urine thromboxane as an immunologic monitor in kidney transplant patients. | 1984 | Transplant. Proc. | pmid:6390872 |
Foegh ML et al. | Monitoring of rat heart allograft rejection by urinary thromboxane. | 1984 | Transplant. Proc. | pmid:6390873 |
Willerson JT et al. | Conversion from chronic to acute coronary artery disease: speculation regarding mechanisms. | 1984 | Am. J. Cardiol. | pmid:6391133 |
Fareed J et al. | Molecular markers of contrast media-induced adverse reactions. | 1984 | Semin. Thromb. Hemost. | pmid:6393351 |
Takeda H et al. | [Alternations in coagulation and fibrinolysis associated with extracorporeal circulation--the role of vasoactive prostanoids]. | 1984 | Rinsho Kyobu Geka | pmid:6395300 |
Tada M et al. | Reduction of prostacyclin synthesis as a possible cause of transient flow reduction in a partially constricted canine coronary artery. | 1984 | J. Mol. Cell. Cardiol. | pmid:6398370 |
Stimler NP | Spasmogenic activity of C5adesArg anaphylatoxin on guinea pig lung parenchymal strips: sensitivity of the leukotriene-mediated component to cyclooxygenase inhibitors. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6440564 |
Ylikorkala O | Prostanoids in gynaecology. | 1984 | Ann. Clin. Res. | pmid:6398666 |
Vapaatalo H et al. | Prostanoids in blood pressure regulation and their role in the blood pressure lowering effects induced by changes in dietary fats. | 1984 | Ann. Clin. Res. | pmid:6398981 |
Wang JP et al. | XC 386: a new antiplatelet agent. | 1984 | Thromb. Res. | pmid:6438827 |
Driss F et al. | Inhibition of platelet aggregation and thromboxane synthesis after intake of small amount of icosapentaenoic acid. | 1984 | Thromb. Res. | pmid:6098051 |
Fuller RW et al. | Dexamethasone inhibits the production of thromboxane B2 and leukotriene B4 by human alveolar and peritoneal macrophages in culture. | 1984 | Clin. Sci. | pmid:6091982 |
Dahl ML and Uotila P | Salicylate does not interfere with aspirin in human blood in vivo. | 1984 | Prostaglandins Leukot Med | pmid:6585840 |
Dahl ML and Uotila P | Thromboxane formation during blood clotting is decreased by verapamil. | 1984 | Prostaglandins Leukot Med | pmid:6585842 |
Walenga RW et al. | Recovery of megakaryocyte thromboxane production in vitro after aspirin inhibition. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6712680 |
Turk J et al. | Arachidonic acid metabolism in isolated pancreatic islets. I. Identification and quantitation of lipoxygenase and cyclooxygenase products. | 1984 | Biochim. Biophys. Acta | pmid:6329307 |
Zipser RD and Smorlesi C | Regulation of urinary thromboxane B2 in man: influence of urinary flow rate and tubular transport. | 1984 | Prostaglandins | pmid:6718753 |
Gal D et al. | Effect of radiation on prostaglandin production by human bowel in vitro. | 1984 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:6588048 |
Kutti J et al. | The effect of acetylsalicylic acid in 3 different formulations on in vitro and in vivo platelet function tests. An experimental study on healthy male volunteers. | 1984 | Scand J Haematol | pmid:6719042 |
Oglesby TD and Gorman RR | The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. | 1984 | Biochim. Biophys. Acta | pmid:6424715 |
Holme S et al. | The effect of albumin bound polyunsaturated fatty acids on human platelets. | 1984 | Thromb. Haemost. | pmid:6719386 |
Eldor A et al. | The effect of oral administration of dipyrone on the capacity of blood platelets to synthesize thromboxane A2 in man. | 1984 | Eur. J. Clin. Pharmacol. | pmid:6723755 |
Cerletti C et al. | Plasma levels of salicylate and aspirin in healthy volunteers: relevance to drug interaction on platelet function. | 1984 | J. Lab. Clin. Med. | pmid:6726057 |
Anderson CB et al. | Renal thromboxane synthesis in excised kidney distal to renovascular lesions. | 1984 | JAMA | pmid:6726983 |
Grignani G et al. | Activation of platelet prostaglandin biosynthesis pathway during neoplastic cell-induced platelet aggregation. | 1984 | Thromb. Res. | pmid:6729776 |
Tremoli E et al. | Increased platelet sensitivity and thromboxane B2 formation in type-II hyperlipoproteinaemic patients. | 1984 | Eur. J. Clin. Invest. | pmid:6437830 |