MeSH term | MeSH ID | Detail |
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Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhao Y et al. | [The effect of desloratadine on the TXB2 and leukotrienes levels in the nasal lavage fluid of allergic rhinitis animal model]. | 2005 | Lin Chuang Er Bi Yan Hou Ke Za Zhi | pmid:16075993 |
Yoshino T et al. | Pharmacological profile of celecoxib, a specific cyclooxygenase-2 inhibitor. | 2005 | Arzneimittelforschung | pmid:16080279 |
Mancini F et al. | Time since menopause does not affect plasma viscosity, plasma thromboxane levels and Doppler findings. | 2005 | Gynecol. Endocrinol. | pmid:16019357 |
Mancini F et al. | Effects of hormone replacement therapy on plasma viscosity and Doppler variations in postmenopausal non-smokers and heavy smokers. | 2005 | Gynecol. Endocrinol. | pmid:16019365 |
Michibayashi T | Platelet aggregation and vasoconstriction related to platelet cyclooxygenase and 12-lipoxygenase pathways. | 2005 | J. Atheroscler. Thromb. | pmid:16020916 |
Svenstrup Poulsen T et al. | A critical appraisal of the phenomenon of aspirin resistance. | 2005 | Cardiology | pmid:16020925 |
Walsh DS et al. | Characterization of circulating monocytes expressing HLA-DR or CD71 and related soluble factors for 2 weeks after severe, non-thermal injury. | 2005 | J. Surg. Res. | pmid:16045935 |
Rodrigue ME et al. | Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats. | 2005 | Can. J. Physiol. Pharmacol. | pmid:16049546 |
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Sullivan JC et al. | Sexual dimorphism in renal production of prostanoids in spontaneously hypertensive rats. | 2005 | Hypertension | pmid:15699443 |
Coppola A et al. | Reduced in vivo oxidative stress following 5-methyltetrahydrofolate supplementation in patients with early-onset thrombosis and 677TT methylenetetrahydrofolate reductase genotype. | 2005 | Br. J. Haematol. | pmid:16173969 |
Blume C et al. | Different effect of cyclosporine A and mycophenolate mofetil on passive Heymann nephritis in the rat. | 2005 | Nephron Exp. Nephrol. | pmid:15855806 |
Giraudel JM et al. | Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in cats. | 2005 | Am. J. Vet. Res. | pmid:15900953 |
Song YM et al. | Effects of scorpion venom bioactive polypolypeptides on platelet aggregation and thrombosis and plasma 6-keto-PG F1alpha and TXB2 in rabbits and rats. | 2005 | Toxicon | pmid:15975616 |
Hsiao G et al. | Protective mechanisms of inosine in platelet activation and cerebral ischemic damage. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15976325 |
Montuschi P et al. | Effects of cyclo-oxygenase inhibition on exhaled eicosanoids in patients with COPD. | 2005 | Thorax | pmid:16192367 |
Barbara J et al. | Prevention of latex sensitization in guinea pigs by a bacterial and viral filter used in anaesthesia. | 2005 | Br J Anaesth | pmid:15980041 |
Hsiao G et al. | alpha-Naphthoflavone, a potent antiplatelet flavonoid, is mediated through inhibition of phospholipase C activity and stimulation of cyclic GMP formation. | 2005 | J. Agric. Food Chem. | pmid:15969494 |
Munsterhjelm E et al. | Characterization of inhibition of platelet function by paracetamol and its interaction with diclofenac in vitro. | 2005 | Acta Anaesthesiol Scand | pmid:15954969 |
Vangroenweghe F et al. | Effect of carprofen treatment following experimentally induced Escherichia coli mastitis in primiparous cows. | 2005 | J. Dairy Sci. | pmid:15956299 |
Wakamoto S et al. | Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro. | 2005 | Artif Cells Blood Substit Immobil Biotechnol | pmid:15960075 |
Al Kadi H et al. | A prospective, longitudinal study of the renin-angiotensin system, prostacyclin and thromboxane in the first trimester of normal human pregnancy: association with birthweight. | 2005 | Hum. Reprod. | pmid:16006463 |
Beretta C et al. | COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. | 2005 | Pharmacol. Res. | pmid:15939622 |
Klein Gunnewiek JM et al. | The influence of acetylsalicylic acid intake by healthy volunteers on duplicate PFA-100 measurements. | 2005 | Blood Coagul. Fibrinolysis | pmid:15970717 |
Jin YR et al. | An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets. | 2005 | Basic Clin. Pharmacol. Toxicol. | pmid:16128910 |
Haubelt H et al. | Can platelet function tests predict the clinical efficacy of aspirin? | 2005 | Semin. Thromb. Hemost. | pmid:16149017 |
Ueda T and Hashimoto T | [Thromboxane A2 (TXA2), thromboxane B2 (TXB2)]. | 2005 | Nippon Rinsho | pmid:16149442 |
Francois H et al. | Prostacyclin protects against elevated blood pressure and cardiac fibrosis. | 2005 | Cell Metab. | pmid:16154102 |
Jermany J et al. | Lumiracoxib does not affect the ex vivo antiplatelet aggregation activity of low-dose aspirin in healthy subjects. | 2005 | J Clin Pharmacol | pmid:16172182 |
Persico N et al. | Transdermal HRT and Doppler findings in normotensive and hypertensive postmenopausal patients. | 2005 | Ultrasound Obstet Gynecol | pmid:16184506 |
Perini JA et al. | Influence of CYP2C9 genotypes on the pharmacokinetics and pharmacodynamics of piroxicam. | 2005 | Clin. Pharmacol. Ther. | pmid:16198655 |
Davì G et al. | Helicobacter pylori infection causes persistent platelet activation in vivo through enhanced lipid peroxidation. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15472127 |
Maree AO et al. | Platelet response to low-dose enteric-coated aspirin in patients with stable cardiovascular disease. | 2005 | J. Am. Coll. Cardiol. | pmid:16198840 |
Kataoka M et al. | A long-acting prostacyclin agonist with thromboxane inhibitory activity for pulmonary hypertension. | 2005 | Am. J. Respir. Crit. Care Med. | pmid:16192456 |
Munsterhjelm E et al. | Dose-dependent inhibition of platelet function by acetaminophen in healthy volunteers. | 2005 | Anesthesiology | pmid:16192763 |
Léger CL et al. | A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes. | 2005 | Eur J Clin Nutr | pmid:15798774 |
Stichtenoth DO et al. | Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. | 2005 | Kidney Int. | pmid:16221219 |
Saloheimo P et al. | Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage. | 2005 | Thromb. Res. | pmid:15733969 |
Trebino CE et al. | Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. | 2005 | J. Biol. Chem. | pmid:15722356 |
Fimognari FL et al. | Nocturnal rise of urinary thromboxane B 2 in patients with coronary artery disease. | 2005 | Thromb. Haemost. | pmid:15735822 |
Mayer AM et al. | Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. | 2005 | BMC Pharmacol. | pmid:15762999 |
Kalaitzis C et al. | Effects of renal denervation of the contralateral kidney on blood pressure and sodium and eicosanoid excretion in the chronic phase of two-kidney, one-clip renovascular hypertension in rats. | 2005 | Scand. J. Urol. Nephrol. | pmid:15764265 |
GarcÃa-Saura MF et al. | Effects of chronic quercetin treatment in experimental renovascular hypertension. | 2005 | Mol. Cell. Biochem. | pmid:15792364 |
Awad AS et al. | Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. | 2005 | Am. J. Hypertens. | pmid:15831366 |
De Candia E et al. | Abnormal pH-sensing of platelet Na+/H+ exchanger in patients with cardiac syndrome X. | 2005 | Int. J. Cardiol. | pmid:15837078 |
Capone ML et al. | Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects. | 2005 | J. Am. Coll. Cardiol. | pmid:15837265 |
Oliveira RL et al. | Postmenopausal hormone replacement therapy increases plasmatic thromboxane beta 2. | 2005 | Int. J. Cardiol. | pmid:15771927 |
Cryer B et al. | Double-blind, randomized, parallel, placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-treated healthy adult volunteers. | 2005 | Clin Ther | pmid:15811481 |
Lappegård KT et al. | Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production. | 2005 | Ann. Thorac. Surg. | pmid:15734405 |
Gerasimovska-Kitanovska B et al. | Decreased nitric oxide in women with essential hypertension in prehypertensive phase. | 2005 | Croat. Med. J. | pmid:16342341 |