MeSH term | MeSH ID | Detail |
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Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nádasy GL et al. | Role of endothelium, oxygen and ionic milieu in the prostacyclin and thromboxane production of rat aortic tissue slices. | 1991 | Acta Physiol Hung | pmid:1763652 |
Khan HH et al. | Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. | 2000 | Acta Pharmacol. Sin. | pmid:11501061 |
Wang W et al. | Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. | 2000 | Acta Pharmacol. Sin. | pmid:11501172 |
Wang YY et al. | Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. | 2004 | Acta Pharmacol. Sin. | pmid:15066215 |
Wang LL et al. | Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. | 2000 | Acta Pharmacol. Sin. | pmid:11360670 |
Peng LL et al. | Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. | 2016 | Acta Pharmacol. Sin. | pmid:27641736 |
Säynävälammi P | Effects of captopril on the urinary excretion of prostanoids and kallikrein in spontaneously hypertensive rats. | 1986 | Acta Pharmacol Toxicol (Copenh) | pmid:3541494 |
Vinge E and Björkman S | Compared effects of the two antiinflammatory drugs indoprofen and lonazolac on thromboxane generation and on platelet aggregation, related to plasma concentrations after single oral doses. | 1986 | Acta Pharmacol Toxicol (Copenh) | pmid:3799197 |
Vinge E et al. | Single intravenous and oral doses of fenflumizole: pharmacokinetics and effects on prostanoid formation. | 1985 | Acta Pharmacol Toxicol (Copenh) | pmid:3840639 |
Karhumäki E | Effect of leukocyte and other tissue dialysates on NBT reduction and prostaglandin production in mice. | 1987 | Acta Pathol Microbiol Immunol Scand C | pmid:2831694 |
Sood BG et al. | PGE2/TXB2 imbalance in neonatal hypoxemic respiratory failure. | 2007 | Acta Paediatr. | pmid:17376184 |
Leonhardt A et al. | Reference intervals and developmental changes in urinary prostanoid excretion in healthy newborns, infants and children. | 1992 | Acta Paediatr. | pmid:1511190 |
Safai-Kutti S et al. | Impaired in vivo platelet reactivity in infantile autism. | 1985 | Acta Paediatr Scand | pmid:2931944 |
Hamasaki Y et al. | Studies on the effect of long-term use of low dose aspirin in Kawasaki disease. | 1988 | Acta Paediatr Jpn | pmid:3148261 |
Whittle BJ | Prostaglandin synthetase inhibitors. Drugs which affect arachidonic acid metabolism. | 1979 | Acta Obstet Gynecol Scand Suppl | pmid:111464 |
Ylikorkala O and Viinikka L | Prostaglandins and endometriosis. | 1983 | Acta Obstet Gynecol Scand Suppl | pmid:6344540 |
Ylikorkala O | Prostacyclin and thromboxane during human pregnancy. | 1983 | Acta Obstet Gynecol Scand Suppl | pmid:6344543 |
Koskimies AI et al. | Peritoneal fluid 6-keto-prostaglandin F1 alpha, thromboxane B2 in endometriosis and unexplained infertility. | 1984 | Acta Obstet Gynecol Scand Suppl | pmid:6594012 |
Hayashi M et al. | The levels of five markers of hemostasis and endothelial status at different stages of normotensive pregnancy. | 2002 | Acta Obstet Gynecol Scand | pmid:11966476 |
Saldeen P et al. | Lack of association between Doppler velocimetry and synthesis of prostacyclin and thromboxane in umbilical cord vessels from growth retarded fetuses. | 1995 | Acta Obstet Gynecol Scand | pmid:7900504 |