MeSH term | MeSH ID | Detail |
---|---|---|
Gastric Dilatation | D013271 | 1 associated lipids |
Latex Hypersensitivity | D020315 | 1 associated lipids |
Stomach Volvulus | D013277 | 1 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hyman AL et al. | Prostaglandins and the lung. | 1981 | Med. Clin. North Am. | pmid:7024664 |
Ylikorkala O et al. | Effect of cytostatics on prostaglandin F2 alpha prostacyclin, and thromboxane in patients with gynecologic malignancies. | 1981 | Obstet Gynecol | pmid:7024882 |
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Utsunomiya T et al. | Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). | 1981 | Ann. Surg. | pmid:6117260 |
Mahoney DA et al. | Urinary thromboxane B2 on allograft rejection. | 1981 | Lancet | pmid:6118500 |
Allen JB et al. | Irradiation decreases vascular prostacyclin formation with no concomitant effect on platelet thromboxane production. | 1981 | Lancet | pmid:6118629 |
Stenson WF et al. | Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. | 1981 | Prostaglandins | pmid:6803301 |
Kelly KL and Laychock SG | Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. | 1981 | Prostaglandins | pmid:6803305 |
Sterin-Borda L et al. | Stimulating effect of thromboxane B2 on isolated rat atria. | 1981 | Experientia | pmid:7262286 |
Roberts LJ et al. | Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites. | 1981 | J. Biol. Chem. | pmid:7263660 |
Zijlstra FJ and Vincent JE | Contractile characteristics of the rat stomach strip and the rabbit aorta and mesenteric artery. | 1981 | J Pharmacol Methods | pmid:7265989 |
Gilani SH and Persaud TV | Embryopathic effects of thromboxane B2 in the chick. | 1981 | Prostaglandins Med | pmid:7267828 |
Anderson CB et al. | Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. | 1981 | Transplant. Proc. | pmid:7268892 |
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Malemud CJ et al. | Prostaglandin biosynthesis by lapine articular chondrocytes in culture. | 1981 | Biochim. Biophys. Acta | pmid:6894251 |
Ohnishi H et al. | Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2. | 1981 | Prostaglandins Med | pmid:6894333 |
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She HS et al. | Metabolism of prostaglandin endoperoxide by microsomes from cat lung. | 1981 | Prostaglandins | pmid:6894797 |
Russell NH et al. | Platelet adenine nucleotides and arachidonic acid metabolism in the myeloproliferative disorders. | 1981 | Thromb. Res. | pmid:6794179 |
Ingerman-Wojenski C et al. | Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. | 1981 | Prostaglandins | pmid:6789404 |
Boyd JA and Eling TE | Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. | 1980 Jul 1-15 | Thromb. Res. | pmid:7003800 |
Patrono C et al. | Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. | 1980 Feb 1-15 | Thromb. Res. | pmid:7368167 |
Koh H et al. | A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. | 1980 Feb 1-15 | Thromb. Res. | pmid:7368170 |
Kosaki G et al. | The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. | 1980 Dec 1-15 | Thromb. Res. | pmid:6785893 |
Spagnuolo PJ et al. | Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. | 1980 | J. Clin. Invest. | pmid:6772674 |
Best LC et al. | The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro. | 1980 | Thromb. Haemost. | pmid:6773171 |
Olund A et al. | Prostaglandins and thromboxanes in amniotic fluid during rivanol-induced abortion and labour. | 1980 | Prostaglandins | pmid:6775353 |
Bisordi JE et al. | Interaction of vasopressin and prostaglandins in the toad urinary bladder. | 1980 | J. Clin. Invest. | pmid:6777397 |
Burch RM and Halushka PV | Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. | 1980 | J. Clin. Invest. | pmid:6777398 |
Galli C et al. | Dietary essential fatty acids, tissue fatty acids and prostaglandin synthesis. | 1980 | Prog Food Nutr Sci | pmid:6779348 |
Best LC et al. | Studies on the role of calcium in the control of thromboxane B2 production. | 1980 | Artery | pmid:6783015 |
Challis JR and Patrick JE | The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. | 1980 | Semin. Perinatol. | pmid:6992278 |
Ahnfelt-Rønne I et al. | Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. | 1980 | Agents Actions | pmid:6992544 |
Gullner HG et al. | Correction of increased prostacyclin synthesis in Bartter's syndrome by indomethacin treatment. | 1980 | Prostaglandins Med | pmid:6994153 |
Patrono C et al. | Radioimmunoassay measurement of stable metabolites of platelet arachidonic acid: a convenient method for the in vitro and ex vivo evaluation of cyclo-oxygenase inhibitors. | 1980 | Agents Actions Suppl. | pmid:6787852 |
Brodie MJ et al. | Is prostacyclin in the major pro-inflammatory prostanoid in joint fluid? | 1980 | Life Sci. | pmid:6999274 |
Silver MJ et al. | A model system for studying initial events in atherosclerosis. | 1980 | Artery | pmid:7000044 |
Fitzpatrick TM et al. | Tromboxane B2 inhibits the pulmonary inactivation of prostaglandin E2 in the dog. | 1980 | Br. J. Pharmacol. | pmid:7000216 |
Poyser NL and Scott FM | Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle. | 1980 | J. Reprod. Fertil. | pmid:7001011 |
Lands WE et al. | Recent concepts on platelet function and dietary lipids in coronary thrombosis, vasospasm and angina. | 1980 | Herz | pmid:7007191 |
Subbiah MT et al. | Enhancement of thrombocyte aggregation and thromboxane B2 synthesis by diethylstilbestrol. | 1980 | Pharmacology | pmid:7220591 |
Ali AE et al. | Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cells. | 1980 | Prostaglandins | pmid:7008090 |
Ohtsu E and Matsuzawa T | Metabolic alterations in the endogenous formation of 6 keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in the brain-stem of stroke-resistant spontaneously hypertensive rats. | 1980 | J. Nutr. Sci. Vitaminol. | pmid:7229740 |
Vargaftig BB et al. | Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella. | 1980 | Eur. J. Pharmacol. | pmid:7009169 |
Giri SN and Krishna GA | Development of a dual isotopes techniques and two-stage column chromatography to characterize the prostaglandin F2alpha, E2 and Thromboxane B2 formed by the guinea pig lung. | 1980 | J Pharmacol Methods | pmid:7009992 |
Heggers JP et al. | Evaluation of burn blister fluid. | 1980 | Plast. Reconstr. Surg. | pmid:6770396 |
Mathé AA et al. | Increased content of immunoreactive prostaglandin E in cerebrospinal fluid of patients with schizophrenia. | 1980 | Lancet | pmid:6101355 |
Mestel F et al. | Severe bleeding associated with defective thromboxane synthetase. | 1980 | Lancet | pmid:6101498 |
Pareti FI et al. | Platelets and the vessel wall: how much aspirin? | 1980 | Lancet | pmid:6101829 |
Sanger GJ and Bennett A | Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6103666 |
Harris RH et al. | Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6768234 |
Zahavi J et al. | Enhanced in-vivo platelet release reaction, increased thromboxane synthesis, and decreased prostacyclin release after tourniquet ischaemia. | 1980 | Lancet | pmid:6106784 |
Jécsai G and Bagdány S | Quantitative determination of thromboxane synthesis in blood samples by video-densitometry. | 1980 | Acta Biochim. Biophys. Acad. Sci. Hung. | pmid:7282294 |
Hwang DH | Aggregation and inhibition of rat platelets, and the formation of endoperoxide metabolites. | 1980 | Prostaglandins Med | pmid:7413850 |
Cerskus AL et al. | Thromboxane B2 and 6-keto-prostaglandin F1 alpha synthesis during infusion of collagen and arachidonic acid in rabbits: inhibition by aspirin and sulfinpyrazone. | 1980 | Thromb. Res. | pmid:7414555 |
Tada M et al. | Significance of thromboxane A2 in myocardial ischemia in patients with coronary artery disease. | 1980 | Adv Myocardiol | pmid:7423053 |
Matsumoto M et al. | Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. | 1980 | Thromb. Haemost. | pmid:7423441 |
Davies GC et al. | Elevated plasma fibrinopeptide A and thromboxane B2 levels during cardiopulmonary bypass. | 1980 | Circulation | pmid:6965618 |
Kennedy MS et al. | In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. | 1980 | Prostaglandins | pmid:6967616 |
Galli C et al. | Modulation of prostaglandin production in tissues by dietary essential fatty acids. | 1980 | Acta Med. Scand. Suppl. | pmid:6935943 |
Wong PY et al. | The role of calmodulin in prostaglandin metabolism. | 1980 | Ann. N. Y. Acad. Sci. | pmid:6940495 |
Lefer AM and Crossley K | Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. | 1980 | Adv Shock Res | pmid:7304314 |
Galli C et al. | Effects of 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy carboxyl methoxy coumarin (AD6) on aggregation, arachidonic acid metabolism and thromboxane B2 formation in human platelets. | 1980 | Pharmacol Res Commun | pmid:7393988 |
Oka M and Manku MS | Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets. | 1980 | Prostaglandins Med | pmid:7394062 |
Karmali RA et al. | Intrarenal growth of the Walker 256 tumour and renal vein concentrations of PGE2, PGF 2 alpha, and TXB2: effects of diazepam. | 1980 | Prostaglandins Med | pmid:7394064 |
Cooper JD et al. | Prostaglandin production associated with the pulmonary vascular response to complement activation. | 1980 | Surgery | pmid:7394704 |
Dupont J et al. | Effects of dietary essential fatty acid concentration upon prostanoid synthesis in rats. | 1980 | J. Nutr. | pmid:7400858 |
Rao GH et al. | Influence of epinephrine on the aggregation response of aspirin-treated platelets. | 1980 | Prostaglandins Med | pmid:7403340 |
Schrör K et al. | Preservation of ischemic myocardium by pinane thromboxane A2. | 1980 | Am. J. Physiol. | pmid:7356037 |
Hassid A and Dunn MJ | Microsomal prostaglandin biosynthesis of human kidney. | 1980 | J. Biol. Chem. | pmid:7358683 |
Kadowitz PJ and Hyman AL | Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. | 1980 | J. Pharmacol. Exp. Ther. | pmid:7365689 |
Schlondorff D and Folkert VW | Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369028 |
Van Praag D and Farber SJ | Prostaglandin biosynthesis in normal and ureteral obstructed rabbit kidney; formation of a novel metabolite. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369029 |
Lindgren JA et al. | Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6247886 |
Kot PA et al. | Modification of the cardiovascular actions of prostaglandins by thromboxane B2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369035 |
Friedman LS et al. | Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369063 |
Garfield RE et al. | Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. | 1980 | Am. J. Physiol. | pmid:7369350 |
Lewy RI | Effect of elevated plasma-free fatty acids on thromboxane release in patients with coronary artery disease. | 1980 | Haemostasis | pmid:7372200 |
Powell WS | Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. | 1980 | Prostaglandins | pmid:6258197 |
Cook JA et al. | Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. | 1980 | J. Clin. Invest. | pmid:7350199 |
Stuart MJ et al. | Effect of cholesterol on production of thromboxane b2 by platelets in vitro. | 1980 | N. Engl. J. Med. | pmid:7350406 |
Kent L et al. | Differential response of articular chondrocyte populations to thromboxane B2 and analogs of prostaglandin cyclic endoperoxides. | 1980 | Prostaglandins | pmid:7384546 |
Wise WC et al. | Ibuprofen improves survival from endotoxic shock in the rat. | 1980 | J. Pharmacol. Exp. Ther. | pmid:7452480 |
Subbiah MT et al. | Studies of aggregation and thromboxane B2 synthesis in avian thrombocytes: comparison between atherosclerosis-susceptible and resistant breeds. | 1980 | Thromb. Haemost. | pmid:7455983 |
Pace-Asciak CR and Edwards NS | Tetranor thromboxane B2 is the principal urinary catabolite formed after i.v. infusion of thromboxane B2 in the rat. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7458943 |
Viinikka L and Ylikorkala O | Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay. | 1980 | Prostaglandins | pmid:7465865 |
Lagarde M et al. | Increase of platelet thromboxane A2 formation and of its plasmatic half-life in diabetes mellitus. | 1980 | Thromb. Res. | pmid:7466751 |
Lewy RI et al. | Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature. | 1980 | Circulation | pmid:7371128 |
McManus LM et al. | Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit. | 1980 | J. Immunol. | pmid:7430618 |
Meyers KM et al. | An evaluation of the arachidonate pathway of platelets from companion and food-producing animals, mink, and man. | 1980 | Thromb. Res. | pmid:7209869 |