MeSH term | MeSH ID | Detail |
---|---|---|
Erythromelalgia | D004916 | 1 associated lipids |
Oligomenorrhea | D009839 | 1 associated lipids |
Intracranial Hemorrhage, Hypertensive | D020299 | 1 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Rao GH et al. | Effect of Amrinone, a cardiotonic drug, on hemodynamics and platelet function. | 1981 | Prostaglandins Med | pmid:6784136 |
Strand JC et al. | Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. | 1981 | Am. J. Physiol. | pmid:6787931 |
Stuart MJ et al. | Abnormal platelet function and arachidonate metabolism in chronic idiopathic thrombocytopenic purpura. | 1981 | Blood | pmid:6788109 |
Okamatsu S et al. | Effect of calcium channel blockers on arachidonate-induced sudden death in rabbits. | 1981 | Proc. Soc. Exp. Biol. Med. | pmid:6261265 |
Handin RI and Alexander RW | Humoral heartache -- do platelets have a role? | 1981 | N. Engl. J. Med. | pmid:7010170 |
Robertson RM et al. | Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. | 1981 | N. Engl. J. Med. | pmid:7010173 |
Hladovec J | Prostaglandins and endothelial stability. | 1981 | Arzneimittelforschung | pmid:7011332 |
Sananès N et al. | A role for prostaglandins in decidualization of the rat uterus. | 1981 | J. Endocrinol. | pmid:7012263 |
Kadowitz PJ et al. | Pulmonary vascular responses to prostaglandins. | 1981 | Fed. Proc. | pmid:7014258 |
Ingerman-Wojenski C et al. | Bovine endothelial cells in culture produce thromboxane as well as prostacyclin. | 1981 | J. Clin. Invest. | pmid:7014633 |
Tyler HM et al. | Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase. | 1981 | Lancet | pmid:6110861 |
Vermylen J et al. | Thromboxane synthetase inhibition as antithrombotic strategy. | 1981 | Lancet | pmid:6112447 |
Feuerstein N et al. | 3-deazaadenosine, a transmethylase inhibitor, suppresses the effect of lipopolysaccharide on release of prostacyclin and thromboxane. | 1981 | J. Pharm. Pharmacol. | pmid:6115021 |
Fasce L et al. | [Effects of glucocorticoids on the gastrointestinal tract of normal rats and rats deficient in endogenous prostaglandins]. | 1981 | Boll. Soc. Ital. Biol. Sper. | pmid:7295403 |
Tada M et al. | Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris. | 1981 | Circulation | pmid:7296786 |
Foegh ML et al. | Urine i-TXB2 in renal allograft rejection. | 1981 | Lancet | pmid:6115199 |
McManus LM et al. | Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon. | 1981 | Lab. Invest. | pmid:7300244 |
Utsunomiya T et al. | Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). | 1981 | Ann. Surg. | pmid:6117260 |
Uyama O et al. | Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular disease. | 1981 | Prostaglandins Med | pmid:7302001 |
Mahoney DA et al. | Urinary thromboxane B2 on allograft rejection. | 1981 | Lancet | pmid:6118500 |
Smith JB and Jubiz W | OKY-1581: a selective inhibitor of thromboxane synthesis in vivo and in vitro. | 1981 | Prostaglandins | pmid:7302264 |
Allen JB et al. | Irradiation decreases vascular prostacyclin formation with no concomitant effect on platelet thromboxane production. | 1981 | Lancet | pmid:6118629 |
Rifkin BR and Tai HH | Elevated thromboxane B2 levels in periodontal disease. | 1981 | J. Periodont. Res. | pmid:6453981 |
Mehta J and Mehta P | Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed. | 1981 | Acta Med. Scand. Suppl. | pmid:6948499 |
Stenson WF et al. | Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. | 1981 | Prostaglandins | pmid:6803301 |
Rubenstein MD et al. | Platelet activation in clinical coronary artery disease and spasm. | 1981 | Am. Heart J. | pmid:6455912 |
Walker ID et al. | A double blind study of prostacyclin in cardiopulmonary bypass surgery. | 1981 | Br. J. Haematol. | pmid:6457624 |
Bray MA et al. | Prostaglandin generation by separated human blood mononuclear cell fractions. | 1981 | Int. J. Immunopharmacol. | pmid:6949878 |
Capitanio A et al. | Platelet abnormalities in renal transplantation. | 1981 | Proc Eur Dial Transplant Assoc | pmid:6460244 |
Kelly KL and Laychock SG | Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. | 1981 | Prostaglandins | pmid:6803305 |
Ylikorkala O and Viinikka L | Prostacyclin, thromboxane, and prostaglandin F2 alpha in maternal plasma during breast-feeding. | 1981 | Am. J. Obstet. Gynecol. | pmid:7011034 |
Kinney EL and Demers LM | Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon. | 1981 | Prostaglandins Med | pmid:6895673 |
Barnett AH et al. | Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes. | 1981 | Clin. Endocrinol. (Oxf) | pmid:6895721 |
Greenwald JE et al. | Argentation thin layer chromatography of arachidonic acid metabolites isolated from human platelets. | 1981 | Prostaglandins | pmid:7208953 |
Morrison AR et al. | Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue. | 1981 | Prostaglandins | pmid:6894498 |
She HS et al. | Metabolism of prostaglandin endoperoxide by microsomes from cat lung. | 1981 | Prostaglandins | pmid:6894797 |
Hwang DH et al. | In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets. | 1981 | Lipids | pmid:6792442 |
Shaw JO | Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. | 1981 | Prostaglandins | pmid:6789402 |
Tulenko TN | The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. | 1981 | Prostaglandins | pmid:6794096 |
Ingerman-Wojenski C et al. | Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. | 1981 | Prostaglandins | pmid:6789404 |
Williamson EM et al. | Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester. | 1981 | Biochem. Pharmacol. | pmid:6794576 |
Ylikorkala O et al. | Prostacyclin and thromboxane in diabetes. | 1981 | Br Med J (Clin Res Ed) | pmid:6794795 |
Lee SH et al. | Prostacyclin and thromboxane A2 in thrombotic thrombocytopenic purpura. | 1981 | Br Med J (Clin Res Ed) | pmid:6797537 |
Morris HG et al. | Variables associated with radioimmunoassay of prostaglandins in plasma. | 1981 | Prostaglandins | pmid:6803306 |
Feuerstein N and Ramwell PW | OKY-1581, a potential selective thromboxane synthetase inhibitor. | 1981 | Eur. J. Pharmacol. | pmid:7195815 |
Satoh H et al. | Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. | 1981 | Prostaglandins | pmid:7197382 |
Steinhauer HB and Hertting G | Lowering of the convulsive threshold by non-steroidal anti-inflammatory drugs. | 1981 | Eur. J. Pharmacol. | pmid:7202518 |
Robson MC and Heggers JP | Evaluation of hand frostbite blister fluid as a clue to pathogenesis. | 1981 | J Hand Surg Am | pmid:7204918 |
Wilhelm TE et al. | Selective inhibitors of platelet lipoxygenase: 4,7,10,13-eicosatetraynoic acid and 5,8,11,14-henicosatetraynoic acid. | 1981 | Prostaglandins | pmid:6784191 |
Subbiah MT et al. | Effect of specific estrogens on prostaglandin synthesis in aorta and thrombocytes of female pigeons. | 1981 | Proc. Soc. Exp. Biol. Med. | pmid:7208490 |