MeSH term | MeSH ID | Detail |
---|---|---|
Acute Coronary Syndrome | D054058 | 11 associated lipids |
Airway Remodeling | D056151 | 3 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Schuette AH et al. | Effect of lung thromboxane generation on regional blood flow during sheep bypass. | 1982 | Am. J. Physiol. | pmid:7065206 |
Yamamoto S et al. | Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock. | 1997 | Am. J. Physiol. | pmid:9087598 |
Düsing R et al. | Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. | 1983 | Am. J. Physiol. | pmid:6337507 |
Olson KR et al. | Cardiovascular effects of homologous bradykinin in rainbow trout. | 1997 | Am. J. Physiol. | pmid:9140009 |
Strand JC et al. | Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. | 1981 | Am. J. Physiol. | pmid:6787931 |
Nishijima MK et al. | Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig. | 1988 | Am. J. Physiol. | pmid:3394818 |
Katusić ZS et al. | Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. | 1993 | Am. J. Physiol. | pmid:8456988 |
Simonson MS et al. | Identification and transmembrane signaling of leukotriene D4 receptors in human mesangial cells. | 1988 | Am. J. Physiol. | pmid:2849305 |
Olson NC et al. | Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs. | 1993 | Am. J. Physiol. | pmid:8460710 |
Chang SW and Ohara N | Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. | 1993 | Am. J. Physiol. | pmid:8460713 |
Widdicombe JH et al. | Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human. | 1989 | Am. J. Physiol. | pmid:2514604 |
Zipser RD and Martin K | Urinary excretion of arterial blood prostaglandins and thromboxanes in man. | 1982 | Am. J. Physiol. | pmid:6950668 |
Amsterdam EA et al. | Contractile actions of C5a on isolated porcine myocardium. | 1992 | Am. J. Physiol. | pmid:1357981 |
Dobner P and Engelmann B | Low-density lipoproteins supply phospholipid-bound arachidonic acid for platelet eicosanoid production. | 1998 | Am. J. Physiol. | pmid:9814996 |
Del Maschio A et al. | Platelet activation by polymorphonuclear leukocytes exposed to chemotactic agents. | 1990 | Am. J. Physiol. | pmid:2156456 |
Kruse-Elliott KT and Olson NC | CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. | 1993 | Am. J. Physiol. | pmid:8386479 |
Perlman MB et al. | Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect. | 1987 | Am. J. Physiol. | pmid:3030141 |
Schlondorff D and Satriano JA | Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. | 1985 | Am. J. Physiol. | pmid:2579584 |
Adler S et al. | Biphasic effect of oxygen radicals on prostaglandin production by rat mesangial cells. | 1987 | Am. J. Physiol. | pmid:3105332 |
Cudd TA and Wood CE | Thromboxane A2 receptor antagonism prevents hormonal and cardiovascular responses to mineral acid infusion. | 1994 | Am. J. Physiol. | pmid:7977850 |
Benigni A et al. | Renal metabolism and urinary excretion of thromboxane B2 in the rat. | 1989 | Am. J. Physiol. | pmid:2750927 |
Garfield RE et al. | Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. | 1980 | Am. J. Physiol. | pmid:7369350 |
Lampugnani MG and de Gaetano G | Effects of metabolized and unmetabolized arachidonate on rat platelet shape change. | 1984 | Am. J. Physiol. | pmid:6433724 |
Ahlquist DA et al. | Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. | 1983 | Am. J. Physiol. | pmid:6401937 |
Murray MJ et al. | Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. | 1995 | Am. J. Physiol. | pmid:8594921 |
Townsley MI et al. | Pulmonary embolism: analysis of endothelial pore sizes in canine lung. | 1988 | Am. J. Physiol. | pmid:3189571 |
Nukina S et al. | Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells. | 1994 | Am. J. Physiol. | pmid:8304463 |
Grimminger F et al. | Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension. | 1995 | Am. J. Physiol. | pmid:7611475 |
Reyes AA and Klahr S | Bladder contributes to eicosanoids excreted in urine. | 1990 | Am. J. Physiol. | pmid:2240235 |
Teitelbaum I et al. | Effect of cAMP on prostaglandin E2 production in cultured rat inner medullary collecting tubule cells. | 1986 | Am. J. Physiol. | pmid:3020997 |
Himmelstein SI and Klotman PE | The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats. | 1989 | Am. J. Physiol. | pmid:2527469 |
Geisel J et al. | Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2. | 1994 | Am. J. Physiol. | pmid:7943269 |
Chen L et al. | Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. | 1997 | Am. J. Physiol. | pmid:9362253 |
Martin SE et al. | Neuropeptide Y and coronary vasoconstriction: role of thromboxane A2. | 1992 | Am. J. Physiol. | pmid:1415751 |
Don BR et al. | Dietary protein intake modulates glomerular eicosanoid production in the rat. | 1989 | Am. J. Physiol. | pmid:2539749 |
Podjarny E et al. | Prostanoids in renal failure induced by converting enzyme inhibition in sodium-depleted rats. | 1988 | Am. J. Physiol. | pmid:3162354 |
Gyenes M and De Groot H | Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+. | 1993 | Am. J. Physiol. | pmid:8384798 |
Brown GP and Venuto RC | In vitro renal eicosanoid production during pregnancy in rabbits. | 1988 | Am. J. Physiol. | pmid:3287949 |
Perico N et al. | Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporin A. | 1986 | Am. J. Physiol. | pmid:3094383 |
Bradley LM et al. | Circulatory effects of PAF-acether in newborn piglets. | 1989 | Am. J. Physiol. | pmid:2912183 |
Prosdocimi M et al. | Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. | 1985 | Am. J. Physiol. | pmid:3838623 |
Coceani F et al. | Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. | 1983 | Am. J. Physiol. | pmid:6574712 |
Fletcher MP et al. | C5a-induced myocardial ischemia: role for CD18-dependent PMN localization and PMN-platelet interactions. | 1993 | Am. J. Physiol. | pmid:7902015 |
Toda N et al. | Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. | 1992 | Am. J. Physiol. | pmid:1558175 |
Kauser K and Rubanyi GM | Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae. | 1994 | Am. J. Physiol. | pmid:7810731 |
Lorenz RR and Vanhoutte PM | Prejunctional adrenergic inhibition by aggregating platelets in canine blood vessels. | 1985 | Am. J. Physiol. | pmid:4037113 |
Sirko S et al. | Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens. | 1989 | Am. J. Physiol. | pmid:2784289 |
Brown GP and Venuto RC | Eicosanoid production in rabbit vascular tissues and placentas. | 1990 | Am. J. Physiol. | pmid:2316640 |
Raj JU and Chen P | Role of eicosanoids in hypoxic vasoconstriction in isolated lamb lungs. | 1987 | Am. J. Physiol. | pmid:2820247 |
Dunham BM et al. | Role of prostaglandins in positive end-expiratory pressure-induced negative inotropism. | 1981 | Am. J. Physiol. | pmid:7034549 |