Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Coronary Syndrome D054058 11 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Kidney Injury D058186 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Thromboxane b2?

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Greer IA et al. Inhibition of thromboxane and prostacyclin production in whole blood by adrenoceptor antagonists. 1985 Prostaglandins Leukot Med pmid:2865745
Mikhailidis DP et al. The effect of non-specific beta-blockade on metabolic and haemostatic variables during hypoglycaemia. 1985 Diabetes Res. pmid:2866057
Mehta J et al. Increase in human platelet alpha 2-adrenergic receptor affinity for agonist in unstable angina. 1985 J. Lab. Clin. Med. pmid:2866219
Greer IA et al. A comparative study of the effects of adrenoceptor antagonists on platelet aggregation and thromboxane generation. 1985 Thromb. Haemost. pmid:2867620
Habenicht AJ et al. Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase. 1985 J. Clin. Invest. pmid:3921570
Gragnoli G et al. Effects of somatostatin on the behaviour of thromboxane B2 and beta-thromboglobulin in type I diabetes. 1985 Acta Endocrinol. pmid:2408435
Yardumian DA et al. Platelet hyperaggregability occurring during prolonged continuous intravenous infusions of prostacyclin analogue ZK 36374. 1985 Br. J. Haematol. pmid:2408653
Patrassi GM et al. Contact phase of coagulation in diabetes mellitus after aspirin administration. 1985 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:2410343
Safai-Kutti S et al. Plasma concentrations of platelet-specific proteins and serum thromboxane B2 production in response to treatment with dipyridamole. A pilot study of 27 post-myocardial infarction patients. 1985 Eur. Heart J. pmid:2412820
Demling RH et al. Early lung dysfunction after major burns: role of edema and vasoactive mediators. 1985 J Trauma pmid:2413227
Patscheke H Thromboxane synthase inhibition potentiates washed platelet activation by endogenous and exogenous arachidonic acid. 1985 Biochem. Pharmacol. pmid:3922373
Schlondorff D and Satriano JA Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. 1985 Am. J. Physiol. pmid:2579584
Lord A et al. Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. 1985 Prostaglandins pmid:3923570
Shorr RI et al. In vitro effects of acetaminophen and its analogues on human platelet aggregation and thromboxane B2 synthesis. 1985 Thromb. Res. pmid:3923647
Francos GC et al. Dialysis-induced hypoxemia: membrane dependent and membrane independent causes. 1985 Am. J. Kidney Dis. pmid:3919574
Ouwendijk RJ et al. Production of leukotrienes and prostaglandins by human ascites cells. 1985 Eur. J. Clin. Invest. pmid:3007158
Jakubowski JA et al. Cumulative antiplatelet effect of low-dose enteric coated aspirin. 1985 Br. J. Haematol. pmid:3927970
Mehta J et al. Influence of selective thromboxane synthetase blocker CGS-13080 on thromboxane and prostacyclin biosynthesis in whole blood: evidence for synthesis of prostacyclin by leukocytes from platelet-derived endoperoxides. 1985 J. Lab. Clin. Med. pmid:3928780
Brown CG and Poyser NL Further studies on prostaglandin and thromboxane production by the rat uterus during the oestrous cycle. 1985 J. Reprod. Fertil. pmid:3857345
Sawada M et al. Enzyme-immunoassay of thromboxane B2 at the picogram level. 1985 Prostaglandins pmid:3929333
De Caterina R et al. Low-dose aspirin in patients recovering from myocardial infarction. Evidence for a selective inhibition of thromboxane-related platelet function. 1985 Eur. Heart J. pmid:3930246
Beatty CH et al. Metabolism of arachidonic acid by macaque platelets. Implications for studies on atherosclerosis. 1985 Atherosclerosis pmid:3924062
Gorczynska E et al. [Effect of various stimulators on cyclooxygenase activity, platelet aggregation and TxB2 synthesis after using a platelet inhibitor (Aspro Clear) in vivo and in vitro]. 1985 Wiad. Lek. pmid:3933184
Berman B et al. Interferon enhancement of HLA-DR antigen expression on epidermal Langerhans cells. 1985 J. Invest. Dermatol. pmid:2578172
Honda M et al. Effects of purified hog pancreatic kallikrein on the kinin-prostaglandin system and renin-angiotensin-aldosterone system. 1985 Nephron pmid:2993934
Shayevitz JR et al. Inhalation anesthetics augment oxidant-induced pulmonary vasoconstriction: evidence for a membrane effect. 1985 Anesthesiology pmid:3933385
Mehta P et al. Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. 1985 Am J Pediatr Hematol Oncol pmid:2994511
Patrono C et al. Clinical pharmacology of platelet cyclooxygenase inhibition. 1985 Circulation pmid:3933848
Baud L et al. Lipoxygenase products mediate the attachment of rat macrophages to glomeruli in vitro. 1985 Kidney Int. pmid:3927056
Gee MH et al. Eicosanoids, leukocytes and lung injury. 1985 Prog. Clin. Biol. Res. pmid:3934681
Benigni A et al. Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated? 1985 Am. J. Nephrol. pmid:2996352
Leslie JB and Watkins WD Eicosanoids in the central nervous system. 1985 J. Neurosurg. pmid:2997413
Darius H et al. Beneficial effects of a new potent and specific thromboxane receptor antagonist (SQ-29,548) in vitro and in vivo. 1985 J. Pharmacol. Exp. Ther. pmid:2997428
Zavagli G et al. Platelet aggregation and evaluation of the ratio thromboxane B2/6-keto-prostaglandin F1 alpha in the plasma of patients on long term cimetidine treatment. 1985 Prostaglandins Leukot Med pmid:2997804
Sinzinger H Double blind study of the influence of co-dergocrine on platelet parameters in healthy volunteers. 1985 Eur. J. Clin. Pharmacol. pmid:2998802
Wenger H et al. Pulmonary dysfunction secondary to soft-tissue endotoxin. 1985 Arch Surg pmid:3883949
Schambelan M et al. Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus. 1985 J. Clin. Invest. pmid:3156147
Schafer AI and Adelman B Plasmin inhibition of platelet function and of arachidonic acid metabolism. 1985 J. Clin. Invest. pmid:3156149
Sirois P et al. Role of cyclooxygenase products in the lung action of leukotrienes A4, B4, C4, D4 and E4. 1985 Pharmacology pmid:2997811
Klotman PE et al. Captopril enhances aminoglycoside nephrotoxicity in potassium-depleted rats. 1985 Kidney Int. pmid:2422431
Túri S et al. [Changes in serum prostaglandin metabolites in Schönlein-Henoch purpura]. 1985 Orv Hetil pmid:3897944
Farias LR et al. Effect of prostaglandin blockers on ascites fluid in pancreatitis. 1985 Surgery pmid:3898455
Kubo K and Kobayashi T Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep. 1985 Am. Rev. Respir. Dis. pmid:3898941
Barst RJ and Stalcup SA Endothelial function in clinical pulmonary hypertension. 1985 Chest pmid:3899537
Pediconi M et al. Effects of acute and chronic ethanol administration on thromboxane and prostacyclin levels and release in rat brain cortex. 1985 Prostaglandins pmid:3901122
Neri Serneri GG et al. Abnormal cardiocoronary thromboxane A2 production in patients with unstable angina. 1985 Am. Heart J. pmid:3984828
Vesterqvist O et al. In vivo production of thromboxane in acute human myocardial infarction: a preliminary study. 1985 Thromb. Res. pmid:3992528
Wirthumer-Hoche C and Sinzinger H [Protein binding of thromboxane--one of the sources of error in thromboxane determination]. 1985 Wien. Klin. Wochenschr. pmid:3993037
Croft KD et al. Onset of changes in phospholipid fatty acid composition and prostaglandin synthesis following dietary manipulation with n-6 and n-3 fatty acids in the rat. 1985 Biochim. Biophys. Acta pmid:3995069
Eldor A et al. Platelet interaction with subendothelial extracellular matrix: platelet-fibrinogen interactions are essential for platelet aggregation but not for the matrix-induced release reaction. 1985 Blood pmid:3995180
O'Byrne PM et al. Leukotriene B4 induces airway hyperresponsiveness in dogs. 1985 J. Appl. Physiol. pmid:3001017
Mayfield RK et al. Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients. 1985 Diabetes pmid:3930325
Tanaka M and Shibata Y The different response of guinea pig peritoneal macrophages to various stimulators. 1985 Gen. Pharmacol. pmid:3930344
Preud'homme Y et al. Metabolism of arachidonic acid in rabbit iris and retina. 1985 Invest. Ophthalmol. Vis. Sci. pmid:3930417
Zahavi J and Zahavi M Enhanced platelet release reaction, shortened platelet survival time and increased platelet aggregation and plasma thromboxane B2 in chronic obstructive arterial disease. 1985 Thromb. Haemost. pmid:3158092
Roy L et al. Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease. 1985 Am. Heart J. pmid:3158183
Pedrinelli R et al. The influence of selective and nonselective prostaglandin inhibition on renin. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159197
Ezra D et al. Effects of platelet-activating factor on coronary hemodynamics and coronary venous plasma levels of TXB2, 6-keto-PGF1 alpha, and leukotriene C4 immunoreactivity in the intact domestic pig heart. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159202
Gensini GF et al. Effects of dipyridamole infusion on local platelet aggregation and local formation of thromboxane A2 in patients with pulmonary hypertension. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159209
Reines HD et al. Dazoxiben in human sepsis and adult respiratory distress syndrome. 1985 Clin. Pharmacol. Ther. pmid:3979000
Wilcox CS et al. Intrarenal prostaglandin release: effects of arachidonic acid and hyperchloremia. 1985 Kidney Int. pmid:3930824
Greco NJ et al. Action of platelet-activating factor on type 1 diabetic human platelets. 1985 J. Lab. Clin. Med. pmid:3981054
Patterson GA et al. Effects of imidazole and indomethacin on fluid balance in isolated sheep lungs. 1985 J. Appl. Physiol. pmid:3884582
Kelley VE et al. A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice. 1985 J. Immunol. pmid:3918111
Krieger BP et al. Mechanisms of interaction between oxygen and granulocytes in hyperoxic lung injury. 1985 J. Appl. Physiol. pmid:3838744
Valentovic MA and Lubawy WC Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. 1985 Prostaglandins Leukot Med pmid:3903777
Bergqvist D et al. The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis. 1985 Thromb. Res. pmid:3838828
Stuart MJ et al. Prostanoids in hemolytic uremic syndrome. 1985 J. Pediatr. pmid:3839015
Nigam S et al. The concentrations of 6-keto-PGF1 alpha and TXB2 in plasma samples from patients with benign and malignant tumours of the breast. 1985 Prostaglandins pmid:3839084
Hamilton TA et al. gamma-Interferon enhances the secretion of arachidonic acid metabolites from murine peritoneal macrophages stimulated with phorbol diesters. 1985 J. Immunol. pmid:3919102
Petroni A et al. Differential effects of various vasoactive drugs on basal and stimulated levels of TXB2 and 6-keto-PGF1 alpha in rat brain. 1985 Prostaglandins pmid:3839085
Zipser RD Effects of selective inhibition of thromboxane synthesis on renal function in humans. 1985 Am. J. Physiol. pmid:3839111
Fink MP et al. Low-dose dopamine preserves renal blood flow in endotoxin shocked dogs treated with ibuprofen. 1985 J. Surg. Res. pmid:3839278
Bornman MS et al. Elevated thromboxane B2 levels during erection. 1985 S. Afr. Med. J. pmid:3839322
Galli C et al. Modification of brain vascular eicosanoids after pharmacological treatment and ischemia in the rat: drugs and brain vascular eicosanoids. 1985 Cephalalgia pmid:3839438
Kimura Y et al. Effects of stilbene derivatives on arachidonate metabolism in leukocytes. 1985 Biochim. Biophys. Acta pmid:3931689
DiMinno G et al. Increased binding of fibrinogen to platelets in diabetes: the role of prostaglandins and thromboxane. 1985 Blood pmid:2981130
Hillbom M et al. Platelet thromboxane formation and bleeding time is influenced by ethanol withdrawal but not by cigarette smoking. 1985 Thromb. Haemost. pmid:4049313
Gairola C and Tai HH Selective inhibition of leukotriene B4 biosynthesis in rat pulmonary alveolar macrophages by dietary selenium deficiency. 1985 Biochem. Biophys. Res. Commun. pmid:2998361
Aviram M et al. Plasma lipoproteins affect platelet malondialdehyde and thromboxane B2 production. 1985 Biochem Med pmid:4052061
Simmet T et al. Modulation of eicosanoid release from anaphylactic guinea-pig heart with 5-benzoyl-a-methyl-2-thiophene acetic acid (tiaprofenic acid). 1985 Arch Int Pharmacodyn Ther pmid:3841634
Rinaldo JE and Dauber JH Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia. 1985 Circ. Shock pmid:4053294
Shingu T [Prostaglandin metabolism in ischemic brain edema]. 1985 Nihon Geka Hokan pmid:3841635
Leffler CW and Busija DW Prostanoids in cortical subarachnoid cerebrospinal fluid and pial arterial diameter in newborn pigs. 1985 Circ. Res. pmid:4053302
Tobian L et al. Prostaglandin alterations in barely hypertensive Dahl S rats. 1985 Trans. Assoc. Am. Physicians pmid:3842205
Ment LR et al. Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension. 1985 J. Neurosurg. pmid:4056903
Di Minno G et al. Platelet dysfunction in uremia. Multifaceted defect partially corrected by dialysis. 1985 Am. J. Med. pmid:3933340
Numano F et al. Coronary spasm, prostaglandin and HLA factors. 1985 Jpn. Circ. J. pmid:3855470
Katoh K et al. [Serial changes in plasma thromboxane and complement in ARDS--effect of the thromboxane synthetase inhibitor]. 1985 Masui pmid:4057547
Purkerson ML et al. Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:3855542
Jackson EK Effects of thromboxane synthase inhibition on vascular responsiveness in the in vivo rat mesentery. 1985 J. Clin. Invest. pmid:4077980
Dahl ML and Uotila P Sodium salicylate does not prevent the inhibitory effect of indomethacin on thromboxane formation in human blood ex vivo. 1985 Prostaglandins Leukot Med pmid:3856282
De Caterina R et al. Equal antiplatelet effects of aspirin 50 or 324 mg/day in patients after acute myocardial infarction. 1985 Thromb. Haemost. pmid:4082090
Kääpä P Immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in neonatal hyperbilirubinemia. 1985 Prostaglandins Leukot Med pmid:3856285
Mallarkey G and Smith GM A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats. 1985 Br. J. Pharmacol. pmid:3156648
Zijlstra FJ and Vincent JE Leukotriene D4 and phospholipase A2 release thromboxane A2 of different origin in the guinea pig lung parenchymal strip. 1985 Prostaglandins Leukot Med pmid:3857642
Salmon JA et al. Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase. 1985 Prostaglandins pmid:2988019
Hutchison AA et al. Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates. 1985 Prostaglandins Leukot Med pmid:3859877
Murphy RC et al. Surgical delay and arachidonic acid metabolites: evidence for an inflammatory mechanism: an experimental study in rats. 1985 Br J Plast Surg pmid:3921087
Sterk PJ et al. Limited maximal airway narrowing in nonasthmatic subjects. Role of neural control and prostaglandin release. 1985 Am. Rev. Respir. Dis. pmid:2864892