Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Coronary Syndrome D054058 11 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Kidney Injury D058186 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Salmon JA Analysis of arachidonic acid metabolites by radioimmunoassay and physicochemical methods. 1980 Mater Med Pol pmid:7019588
Frame MH et al. Inhibition of acid secretion from the rat-isolated gastric mucosa by arachidonic acid and identification of major metabolites. 1980 Adv Prostaglandin Thromboxane Res pmid:6990724
Subbiah MT and Dietemeyer D Altered synthesis of prostaglandins in platelet and aorta from spontaneously diabetic Wistar rats. 1980 Biochem Med pmid:6893150
Ali M and McDonald JW Synthesis of thromboxane B2 and 6-keto-prostaglandin F1 alpha by bovine gastric mucosal and muscle microsomes. 1980 Prostaglandins pmid:6893365
Ohuchi K et al. Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. 1980 Prostaglandins Med pmid:6893750
Chiabrando C et al. Quantitative determination of 6-keto-PGF1 alpha released by rat aorta: comparison of mass fragmentography and high resolution gas chromatography with electron capture detection. 1980 Prostaglandins pmid:6894036
Morris HG and Sherman NA Prostaglandin-like substances in urine of asthmatic patients. 1980 Adv Prostaglandin Thromboxane Res pmid:7377024
Schoene NW et al. Effects of diets varying in fat and P/S ratio on arachidonic acid metabolism in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:7377026
Smith EF et al. Influence of thromboxane inhibition on the severity of myocardial ischemia in cats. 1980 Can. J. Physiol. Pharmacol. pmid:7378931
Ellwood DA et al. Specific changes in the in vitro production of prostanoids by the ovine cervix at parturition. 1980 Prostaglandins pmid:7384553
Lagarde M et al. Nicergoline, an anti-aggregating agent which inhibits release of arachidonic acid from human platelet phospholipids. 1980 Prostaglandins pmid:7384555
Patrono C et al. Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. 1980 Adv Prostaglandin Thromboxane Res pmid:7386257
Langs DA et al. Thromboxane molecules are not hairpin conformers. 1980 Adv Prostaglandin Thromboxane Res pmid:7386281
Lefer AM et al. Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2. 1980 Proc. Natl. Acad. Sci. U.S.A. pmid:6929517
Moretti RL and Lin CY Coronary vasoconstrictor extracted from blood plasma stimulates platelet lipoxidase activity. 1980 Prostaglandins pmid:6770419
Maggi FM et al. Prostaglandin synthetase activity in vascular tissue of male and female rats. 1980 Prostaglandins pmid:6770422
Feinstein MB et al. Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6770602
Ylikorkala O and Viinikka L Thromboxane A2 in pregnancy and puerperium. 1980 Br Med J pmid:7448530
Bone EA et al. The effects of strontium and calcium ions on 5-hydroxytryptamine secretion and thromboxane B2 biosynthesis in washed human platelets. 1980 Biochem. Soc. Trans. pmid:7450206
Mitchell MD Prostaglandins at parturition and in the neonatal infant. 1980 Biochem. Soc. Trans. pmid:7450282