| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acute Coronary Syndrome | D054058 | 11 associated lipids |
| Airway Remodeling | D056151 | 3 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee HI et al. | Response to Suarez-Kurtz's comments on strongly increased exposure of meloxicam in CYP2C9*3/*3 individuals. | 2014 | Pharmacogenet. Genomics | pmid:25003538 |
| Lattanzio S et al. | Circulating dickkopf-1 in diabetes mellitus: association with platelet activation and effects of improved metabolic control and low-dose aspirin. | 2014 | J Am Heart Assoc | pmid:25037197 |
| Santilli F et al. | Circulating myeloid-related protein-8/14 is related to thromboxane-dependent platelet activation in patients with acute coronary syndrome, with and without ongoing low-dose aspirin treatment. | 2014 | J Am Heart Assoc | pmid:25037196 |
| John F et al. | Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin. | 2013 May-Jun | Indian Heart J | pmid:23809385 |
| Dudley A et al. | Cyclooxygenase expression and platelet function in healthy dogs receiving low-dose aspirin. | 2013 Jan-Feb | J. Vet. Intern. Med. | pmid:23278865 |
| Maenthaisong R et al. | Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755755 |
| Postula M et al. | Association of plasma concentrations of salicylic acid and high on ASA platelet reactivity in type 2 diabetes patients. | 2013 | Cardiol J | pmid:23558875 |
| Honma S et al. | Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. | 2013 | Eur. J. Pharmacol. | pmid:23747596 |
| Lee JJ et al. | Antithrombotic and antiplatelet activities of Soshiho-tang extract. | 2013 | BMC Complement Altern Med | pmid:23773779 |
| Kim YJ | Rhamnetin attenuates melanogenesis by suppressing oxidative stress and pro-inflammatory mediators. | 2013 | Biol. Pharm. Bull. | pmid:23739488 |
| Gremmel T et al. | Differential impact of inflammation on six laboratory assays measuring residual arachidonic acid-inducible platelet reactivity during dual antiplatelet therapy. | 2013 | J. Atheroscler. Thromb. | pmid:23739624 |
| Nakamura A et al. | Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension. | 2013 | Circ. J. | pmid:23676973 |
| Wu G et al. | Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. | 2013 | Chem. Pharm. Bull. | pmid:23207681 |
| Vazzana N et al. | Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype. | 2013 | J Am Heart Assoc | pmid:23557750 |
| Shi JJ and Huang LF | [Effects of transcutaneous electrical acupoint stimulation of "Zusanli" (ST 36) on gastric mucosal injury in exercise stress-induced gastric ulcer rats]. | 2013 | Zhen Ci Yan Jiu | pmid:24006661 |
| Steib CJ et al. | Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension. | 2013 | Life Sci. | pmid:24007798 |
| DeFilippis AP et al. | Thromboxane A(2) generation, in the absence of platelet COX-1 activity, in patients with and without atherothrombotic myocardial infarction. | 2013 | Circ. J. | pmid:23985963 |
| Siennicka A et al. | Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? | 2013 | J. Physiol. Pharmacol. | pmid:23959729 |
| Kleinbongard P et al. | Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris. | 2013 | Am. J. Physiol. Heart Circ. Physiol. | pmid:23934849 |
| Chen LB et al. | [Coagulation and prothrombotic state parameters: clinical analysis in early pregnancy]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24284247 |
| Santilli F et al. | Effects of high-amount-high-intensity exercise on in vivo platelet activation: modulation by lipid peroxidation and AGE/RAGE axis. | 2013 | Thromb. Haemost. | pmid:24030807 |
| Dave M and Amin AR | Yin-Yang regulation of prostaglandins and nitric oxide by PGD2 in human arthritis: reversal by celecoxib. | 2013 | Immunol. Lett. | pmid:23603366 |
| Kapłon-Cieślicka A et al. | Predictors of high platelet reactivity during aspirin treatment in patients with type 2 diabetes. | 2013 | Kardiol Pol | pmid:24065375 |
| Jastrzębska M et al. | Factors influencing multiplate whole blood impedance platelet aggregometry measurements, during aspirin treatment in acute ischemic stroke: a pilot study. | 2013 | Blood Coagul. Fibrinolysis | pmid:24071649 |
| Lv GY et al. | Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. | 2013 | J Ethnopharmacol | pmid:24080032 |
| Li H et al. | Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2. | 2013 | PLoS ONE | pmid:24098505 |
| Hau CS et al. | Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. | 2013 | J. Dermatol. Sci. | pmid:23688403 |
| Drew RC et al. | Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans. | 2013 | J. Appl. Physiol. | pmid:23970529 |
| An J et al. | Blocking of thromboxane Aâ‚‚ receptor attenuates airway mucus hyperproduction induced by cigarette smoke. | 2013 | Eur. J. Pharmacol. | pmid:23399768 |
| Leclerc P et al. | Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:24045148 |
| Bai L et al. | [Effects of electro-acupuncture at Zusanli point on gastric and intestinal blood flow in rats with acute necrotizing pancreatitis]. | 2013 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:24490517 |
| Aukema HM et al. | Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome. | 2013 | Br. J. Nutr. | pmid:23151363 |
| Yamamoto M et al. | Effects of continuous ingestion of hesperidin and glucosyl hesperidin on vascular gene expression in spontaneously hypertensive rats. | 2013 | J. Nutr. Sci. Vitaminol. | pmid:24418882 |
| Sun Y et al. | Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats. | 2013 | J Ethnopharmacol | pmid:24041459 |
| d'Emmanuele di Villa Bianca R et al. | Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24019484 |
| Kong X et al. | High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats. | 2013 | J. Vasc. Surg. | pmid:23069071 |
| Brose SA and Golovko MY | Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24113545 |
| Sayers BC et al. | Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23642096 |
| Zulyniak MA et al. | Fish oil supplementation alters circulating eicosanoid concentrations in young healthy men. | 2013 | Metab. Clin. Exp. | pmid:23522836 |
| Reyes JJ et al. | Antiplatelet effect of new lipophilic hydroxytyrosol alkyl ether derivatives in human blood. | 2013 | Eur J Nutr | pmid:22584413 |
| Vasudevan C et al. | The effect of parenteral lipid emulsions on pulmonary hemodynamics and eicosanoid metabolites in preterm infants: a pilot study. | 2013 | Nutr Clin Pract | pmid:24177284 |
| Matsunobu T et al. | Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. | 2013 | J. Lipid Res. | pmid:24009185 |
| Sadilkova L et al. | The effect of selected pre-analytical phase variables on plasma thromboxane Aâ‚‚ measurements in humans. | 2013 | Int J Lab Hematol | pmid:22908995 |
| Brentnall C et al. | Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves. | 2013 | J. Vet. Pharmacol. Ther. | pmid:22913421 |
| Yi X et al. | Platelet response to aspirin in Chinese stroke patients is independent of genetic polymorphisms of COX-1 C50T and COX-2 G765C. | 2013 | J. Atheroscler. Thromb. | pmid:22972377 |
| Barillà F et al. | Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention. | 2013 | Platelets | pmid:22646157 |
| Broekema FI et al. | In vivo hemostatic efficacy of polyurethane foam compared to collagen and gelatin. | 2013 | Clin Oral Investig | pmid:22855267 |
| McMahon GS et al. | Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial. | 2013 | Thromb. Haemost. | pmid:23494053 |
| Dharmasaroja PA et al. | Aspirin nonresponders in patients with ischaemic stroke. | 2013 | Blood Coagul. Fibrinolysis | pmid:23429255 |
| Shiraishi M et al. | Cholesterol enrichment of rabbit platelets enhances the Ca(2+) entry pathway induced by platelet-derived secondary feedback agonists. | 2013 | Life Sci. | pmid:23499558 |
| Larsen SB et al. | Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease. | 2013 | Thromb. Haemost. | pmid:23407706 |
| Lino-dos-Santos-Franco A et al. | Formaldehyde inhalation reduces respiratory mechanics in a rat model with allergic lung inflammation by altering the nitric oxide/cyclooxygenase-derived products relationship. | 2013 | Food Chem. Toxicol. | pmid:23871789 |
| Fox T et al. | Dysregulated heme oxygenase-ferritin system in pterygium pathogenesis. | 2013 | Cornea | pmid:23792437 |
| Borst O et al. | Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation. | 2013 | Cell. Physiol. Biochem. | pmid:23817201 |
| Zhang J et al. | Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats. | 2013 | J Ethnopharmacol | pmid:23685195 |
| Wei XJ et al. | Effects of carboxymethylpachymaran on signal molecules in chicken immunocytes. | 2013 | Int. J. Biol. Macromol. | pmid:23664932 |
| Kang JW et al. | Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans. | 2013 | Phytother Res | pmid:23296979 |
| Snider AJ et al. | Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis. | 2013 | PLoS ONE | pmid:23301082 |
| Xue YT et al. | Effect of anger on endothelial-derived vasoactive factors in spontaneously hypertensive rats. | 2013 | Heart Lung Circ | pmid:23261325 |
| Gao H et al. | Effects of Yerba Mate tea (Ilex paraguariensis) on vascular endothelial function and liver lipoprotein receptor gene expression in hyperlipidemic rats. | 2013 | Fitoterapia | pmid:23266732 |
| Carroll RC et al. | A comparison of VerifyNowR with PlateletMappingR--detected aspirin resistance and correlation with urinary thromboxane. | 2013 | Anesth. Analg. | pmid:23302970 |
| Towhid ST et al. | Stimulation of platelet death by vancomycin. | 2013 | Cell. Physiol. Biochem. | pmid:23363637 |
| Ren R et al. | Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown alga Laminaria japonica in human subjects. | 2013 | Br. J. Nutr. | pmid:23374164 |
| Gautier-Veyret E et al. | Intermittent hypoxia-activated cyclooxygenase pathway: role in atherosclerosis. | 2013 | Eur. Respir. J. | pmid:23060635 |
| Kovarik JJ et al. | Eicosanoid modulation by the short-chain fatty acid n-butyrate in human monocytes. | 2013 | Immunology | pmid:23398566 |
| Xue J et al. | Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats. | 2013 | Chin J Integr Med | pmid:23001461 |
| Reese EA et al. | Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder. | 2012 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22841517 |
| Olson MT et al. | Effect of assay specificity on the association of urine 11-dehydro thromboxane B2 determination with cardiovascular risk. | 2012 | J. Thromb. Haemost. | pmid:23072449 |
| Jarvis GE et al. | A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1). | 2012 | J. Thromb. Haemost. | pmid:22103309 |
| Alizzi AM et al. | Reduction of post-surgical pericardial adhesions using a pig model. | 2012 | Heart Lung Circ | pmid:22078313 |
| Hui C et al. | Changes in coagulation and hemodynamics during pregnancy: a prospective longitudinal study of 58 cases. | 2012 | Arch. Gynecol. Obstet. | pmid:22083312 |
| Hu YY et al. | Six alkaloids inhibit secretion of IL-1α, TXB(2), ET-1 and E-selectin in LPS-induced endothelial cells. | 2012 | Immunol. Invest. | pmid:22087636 |
| Shoeb M and Ramana KV | Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. | 2012 | Free Radic. Biol. Med. | pmid:22067901 |
| Tong Z et al. | Influence of ShuJinHuoXue tablets on ischemia reperfusion injury of animals' skeletal muscle. | 2012 | Molecules | pmid:22801363 |
| Larsen SB et al. | Increased platelet aggregation and serum thromboxane levels in aspirin-treated patients with prior myocardial infarction. | 2012 | Thromb. Haemost. | pmid:22534977 |
| Li C et al. | Reversal of the anti-platelet effects of aspirin and clopidogrel. | 2012 | J. Thromb. Haemost. | pmid:22268852 |
| RodrÃguez-Vilarrupla A et al. | PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats. | 2012 | J. Hepatol. | pmid:22245887 |
| Mullins KB et al. | Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. | 2012 | Vet Anaesth Analg | pmid:22248445 |
| Bednar F et al. | Evaluation of aspirin's effect on platelet function early after coronary artery bypass grafting. | 2012 | J. Cardiothorac. Vasc. Anesth. | pmid:22281116 |
| Cathcart CJ et al. | Lack of inhibitory effect of acetylsalicylic acid and meloxicam on whole blood platelet aggregation in cats. | 2012 | J Vet Emerg Crit Care (San Antonio) | pmid:22316324 |
| Mo J et al. | Expression of interleukin-18 in a rat model of deep vein thrombosis. | 2012 | J Cardiovasc Surg (Torino) | pmid:22318348 |
| Hartanto MD et al. | Urinary 11-dehydro-thromboxane Bâ‚‚ and 2,3-dinor-6-keto-prostaglandin-Fâ‚α in healthy post-menopausal and pre-menopausal women receiving aspirin 100 mg. | 2012 | J. Thromb. Thrombolysis | pmid:22311294 |
| Smith JP et al. | Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome. | 2012 | Hypertension | pmid:22311905 |
| Brivio I et al. | The pulmonary pharmacology of [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide] (2NTX-99), an anti-atherotrombotic compound with therapeutic potential in pathological conditions that target lung vasculature. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:22342851 |
| Lemkes BA et al. | The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus. | 2012 | J. Thromb. Haemost. | pmid:22252020 |
| Matsuzawa S et al. | Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury. | 2012 | Arzneimittelforschung | pmid:22945770 |
| Rocca B et al. | The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes. | 2012 | J. Thromb. Haemost. | pmid:22471290 |
| Lee JJ et al. | Morusinol extracted from Morus alba inhibits arterial thrombosis and modulates platelet activation for the treatment of cardiovascular disease. | 2012 | J. Atheroscler. Thromb. | pmid:22472211 |
| Bruegel M et al. | Sepsis-associated changes of the arachidonic acid metabolism and their diagnostic potential in septic patients. | 2012 | Crit. Care Med. | pmid:22511130 |
| Totani L et al. | Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse. | 2012 | Thromb. Haemost. | pmid:22436970 |
| Ajamieh H et al. | Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. | 2012 | J. Gastroenterol. Hepatol. | pmid:22432744 |
| Shatoor AS et al. | Effect of Hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino Wistar rats. | 2012 | Thromb. Res. | pmid:22261477 |
| Brentnall C et al. | Potency and selectivity of carprofen enantiomers for inhibition of bovine cyclooxygenase in whole blood assays. | 2012 | Res. Vet. Sci. | pmid:22703724 |
| Peters SM et al. | In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration. | 2012 | Vet. Immunol. Immunopathol. | pmid:22648045 |
| Zhou MT et al. | Continuous regional arterial infusion with fluorouracil and octreotide attenuates severe acute pancreatitis in a canine model. | 2012 | PLoS ONE | pmid:22655040 |
| Saadawi S et al. | Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from Mitrella kentii on prostaglandin Eâ‚‚ and Thromboxane Bâ‚‚ production and platelet activating factor receptor binding. | 2012 | Molecules | pmid:22538486 |
| Sadilkova L et al. | The purification step is not crucial in EIA measurements of thromboxane B2 and 11-dehydrothromboxane B2 in human plasma. | 2012 | Clin. Lab. | pmid:22372363 |
| Salama MM et al. | Resistance to low-dose aspirin therapy among patients with acute coronary syndrome in relation to associated risk factors. | 2012 | J Clin Pharm Ther | pmid:23121257 |
| Yokoyama H et al. | Theoretical investigation of aspirin dosage regimen to exhibit optimal antiplatelet effects and decrease risk of upper gastrointestinal lesions. | 2012 | Biol. Pharm. Bull. | pmid:23047244 |
| Liou JT et al. | Levobupivacaine differentially suppresses platelet aggregation by modulating calcium release in a dose-dependent manner. | 2012 | Acta Anaesthesiol Taiwan | pmid:23026170 |