MeSH term | MeSH ID | Detail |
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Acute Coronary Syndrome | D054058 | 11 associated lipids |
Airway Remodeling | D056151 | 3 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nishimaki S and Seki K | An imbalance between prostacyclin and thromboxane in relation to cerebral blood flow in neonates with maternal preeclampsia. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10482286 |
Nawarskas JJ et al. | Effect of aspirin on blood pressure in hypertensive patients taking enalapril or losartan. | 1999 | Am. J. Hypertens. | pmid:10480471 |
Zaitsu M et al. | Induction of cytosolic phospholipase A2 and prostaglandin H2 synthase-2 by lipopolysaccharide in human polymorphonuclear leukocytes. | 1999 | Eur. J. Haematol. | pmid:10480288 |
Fujimoto Y et al. | Sphingomyelin inhibits platelet 12-lipoxygenase activity. | 1999 | Eur. J. Pharmacol. | pmid:10478636 |
Li D et al. | The association of diet and thrombotic risk factors in healthy male vegetarians and meat-eaters. | 1999 | Eur J Clin Nutr | pmid:10477247 |
Gurbel PA et al. | Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477035 |
Feldman M and Cryer B | Aspirin absorption rates and platelet inhibition times with 325-mg buffered aspirin tablets (chewed or swallowed intact) and with buffered aspirin solution. | 1999 | Am. J. Cardiol. | pmid:10468077 |
Hino Y et al. | Changes in endothelium-derived vascular regulatory factors during dobutamine-stress-induced silent myocardial ischemia in patients with Kawasaki disease. | 1999 | Jpn. Circ. J. | pmid:10462014 |
Jiménez R et al. | Involvement of thromboxane A2 in the endothelium-dependent contractions induced by myricetin in rat isolated aorta. | 1999 | Br. J. Pharmacol. | pmid:10455307 |
Sheu JR et al. | The antiplatelet activity of PMC, a potent alpha-tocopherol analogue, is mediated through inhibition of cyclo-oxygenase. | 1999 | Br. J. Pharmacol. | pmid:10455267 |
Melton SM et al. | Mediator-dependent secondary injury after unilateral blunt thoracic trauma. | 1999 | Shock | pmid:10454828 |
Arakida Y et al. | Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10454505 |
Zhang S et al. | Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients. | 1999 | J Tradit Chin Med | pmid:10453582 |
Ogura S et al. | Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria. | 1999 | Shock | pmid:10446890 |
Licker M et al. | Chronic angiotensin converting inhibition does not influence renal hemodynamic and function during cardiac surgery. | 1999 | Can J Anaesth | pmid:10442956 |
Tsugawa K et al. | A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury. | 1999 | J. Gastroenterol. Hepatol. | pmid:10440208 |
Ricetti MM et al. | Effects of sodium selenite on in vitro interactions between platelets and endothelial cells. | 1999 | Int. J. Clin. Lab. Res. | pmid:10436266 |
van Kooten F et al. | Increased thromboxane biosynthesis is associated with poststroke dementia. | 1999 | Stroke | pmid:10436098 |
Kim HS et al. | Effects of tetrandrine and fangchinoline on human platelet aggregation and thromboxane B2 formation. | 1999 | J Ethnopharmacol | pmid:10433485 |
Mills JL et al. | Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. | 1999 | JAMA | pmid:10432033 |