MeSH term | MeSH ID | Detail |
---|---|---|
Acute Coronary Syndrome | D054058 | 11 associated lipids |
Airway Remodeling | D056151 | 3 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Clark IA and Hunt NH | Increased production of arachidonate metabolites by peritoneal cells of mice infected with Plasmodium vinckei vinckei. | 1986 | Aust J Exp Biol Med Sci | pmid:3579736 |
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Gallon LS and Barcelli UO | Measurement of prostaglandin E3 and other eicosanoids in biologic samples using high pressure liquid chromatography and radioimmunoassay. | 1986 | Prostaglandins | pmid:3961201 |
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RodrÃguez-Puyol D et al. | Lack of a direct regulatory effect of atrial natriuretic factor on prostaglandins and renin release by isolated rat glomeruli. | 1986 | Biochem. Biophys. Res. Commun. | pmid:2943276 |
Miller JL et al. | Characterization of a platelet membrane protein of low molecular weight associated with platelet activation following binding by monoclonal antibody AG-1. | 1986 | Blood | pmid:2943333 |
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Ogino M et al. | Plasma thromboxane and prostacyclin: comparison during normal pregnancy and pregnancy complicated by hypertension. | 1986 | Endocrinol. Jpn. | pmid:3530728 |
Pekonen F et al. | Platelet function and coagulation in normal and preeclamptic pregnancy. | 1986 | Thromb. Res. | pmid:2944245 |
Rich S | Primary pulmonary hypertension: recent advances. | 1986 | Herz | pmid:3530928 |
Beitz J et al. | Influence of a cod liver oil diet in healthy and insulin-dependent diabetic volunteers on fatty acid pattern, inhibition of prostacyclin formation by low density lipoprotein (LDL) and platelet thromboxane. | 1986 | Klin. Wochenschr. | pmid:3531705 |
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Srivastava R et al. | Prostanoid mediated effects of centchroman, a non-steroidal oral contraceptive. | 1986 | Agents Actions | pmid:3532722 |
Tomoda H | Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046). | 1986 | Am. Heart J. | pmid:3532743 |
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Goldberg RN et al. | Effects of a leukotriene antagonist on the early hemodynamic manifestations of group B streptococcal sepsis in piglets. | 1986 | Pediatr. Res. | pmid:3534778 |
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Demling RH et al. | Comparison of the postburn hyperdynamic state and changes in lung function (effect of wound bacterial content). | 1986 | Surgery | pmid:3535145 |
Demling RH et al. | The pulmonary and systemic response to recurrent endotoxemia in the adult sheep. | 1986 | Surgery | pmid:3535147 |
Lihrmann I et al. | Role of prostaglandins in calcium-induced corticosteroid secretion by isolated frog interrenal gland. | 1986 | Prostaglandins | pmid:3464040 |
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Maurin N | Routine measurement of thromboxane B2 and the prostacyclin metabolite 6-keto-prostaglandin F1 alpha in plasma. | 1986 | Arzneimittelforschung | pmid:3778554 |
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Peters SP et al. | Mediator release from human lung under conditions of reduced oxygen tension. | 1986 | J. Pharmacol. Exp. Ther. | pmid:2425080 |
Hubbell JA and McIntire LV | Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon. | 1986 | Biomaterials | pmid:3778995 |
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Honda A et al. | Appearance of the arachidonic acid metabolic pathway in human promyelocytic leukemia (HL-60) cells during monocytic differentiation: enhancement of thromboxane synthesis by 1 alpha,25-dihydroxyvitamin D-3. | 1986 | Biochim. Biophys. Acta | pmid:3089289 |
Noonan TC et al. | Mechanism of peptidoleukotriene-induced increases in pulmonary transvascular fluid filtration. | 1986 | J. Appl. Physiol. | pmid:3781998 |
Zhu L et al. | [Effects of sodium beta-3,4-dihydroxyphenyl lactate and beta-phenyl lactic acid on prostacycline and thromboxane A2 contents in the plasma of rabbits after coronary artery occlusion]. | 1986 | Zhongguo Yao Li Xue Bao | pmid:2955643 |
Sigel MM et al. | Phylogenetic studies on lymphokines. Fish lymphocytes respond to human IL-1 and epithelial cells produce an IL-1 like factor. | 1986 | Vet. Immunol. Immunopathol. | pmid:3490047 |
Konturek SJ et al. | Double blind controlled study on the effect of sucralfate on gastric prostaglandin formation and microbleeding in normal and aspirin treated man. | 1986 | Gut | pmid:3492413 |
Flower RJ et al. | A comparison of the acute inflammatory response in adrenalectomised and sham-operated rats. | 1986 | Br. J. Pharmacol. | pmid:3006856 |
Ishibashi M et al. | The diethylhydrogensilyl-cyclic diethylsilylene derivative in the gas chromatography-mass spectrometry of thromboxane B2. | 1986 | Chem. Pharm. Bull. | pmid:3791525 |
Fagan SC et al. | Prostanoid concentrations in human CSF following acute ischaemic brain infarction. | 1986 | Clin. Exp. Pharmacol. Physiol. | pmid:3791712 |
Murdoch WJ | Accumulation of thromboxane B2 within periovulatory ovine follicles: relationship to adhesion of platelets to endothelium. | 1986 | Prostaglandins | pmid:3797693 |
Vinge E and Björkman S | Compared effects of the two antiinflammatory drugs indoprofen and lonazolac on thromboxane generation and on platelet aggregation, related to plasma concentrations after single oral doses. | 1986 | Acta Pharmacol Toxicol (Copenh) | pmid:3799197 |
Bellucci S et al. | Thrombocytopenia with thrombocytopathy possibly related to abnormalities of intracellular Ca++ fluxes and followed by the development of leukaemia. | 1986 | Scand J Haematol | pmid:3085207 |
Kirschenbaum MA | Prostanoids and renal failure. A hypothetical role for prostanoids in progressive renal disease. | 1986 | Contrib Nephrol | pmid:3802815 |
Poll C et al. | Activation of protein kinase C inhibits sodium fluoride-induced elevation of human platelet cytosolic free calcium and thromboxane B2 generation. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3085668 |
Müller G et al. | [Thromboxane analyses in patients with chronic inflammatory bowel diseases]. | 1986 | Dtsch Z Verdau Stoffwechselkr | pmid:3803281 |
Lawson JA et al. | Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. | 1986 | Anal. Biochem. | pmid:3087234 |
Cerletti C et al. | Biochemical selectivity of oral versus intravenous aspirin in rats. Inhibition by oral aspirin of cyclooxygenase activity in platelets and presystemic but not systemic vessels. | 1986 | J. Clin. Invest. | pmid:3088044 |
Walenga RW et al. | Time-dependent inhibition of platelet cyclooxygenase by indomethacin is slowly reversible. | 1986 | Prostaglandins | pmid:3088675 |
Feddersen CO et al. | Acetylcholine induces vasodilation and prostacyclin synthesis in rat lungs. | 1986 | Prostaglandins | pmid:3088679 |
Altman R and Scazziota A | Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake. | 1986 | Thromb. Res. | pmid:3088757 |
Lee CC et al. | Effects of ibuprofen on a pig Pseudomonas ARDS model. | 1986 | J. Surg. Res. | pmid:3090371 |
Peers SH and Hoult JR | Inhibition by ethanol and mepacrine of phospholipase-dependent prostaglandin release from the isolated perfused rat lung. | 1986 | Eur. J. Pharmacol. | pmid:3081357 |
Yui Y et al. | Selective thromboxane A2 synthetase inhibition in vasospastic angina pectoris. | 1986 | J. Am. Coll. Cardiol. | pmid:3941213 |
Kelley VE et al. | Increased renal thromboxane production in murine lupus nephritis. | 1986 | J. Clin. Invest. | pmid:3455932 |
Eynard AR et al. | Aspirin inhibits platelet 12-hydroxy-eicosatetraenoic acid formation. | 1986 | J. Lab. Clin. Med. | pmid:3941295 |
Kobinia GS et al. | Effect of experimental cardiopulmonary bypass on systemic and transcardiac thromboxane B2 levels. | 1986 | J. Thorac. Cardiovasc. Surg. | pmid:3754915 |
Sandler H et al. | Studies on the role of thromboxane in thrombin-induced pulmonary insufficiency in the rat. | 1986 | Thromb. Res. | pmid:3754987 |
Klotman PE et al. | Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. | 1986 | Am. J. Physiol. | pmid:3456211 |
Efimov VV and LadnyÄ AI | [Status of the prostacyclin and thromboxane system, lipid metabolism and lipid peroxidation processes in patients with coronary atherosclerosis]. | 1986 | Vrach Delo | pmid:3754994 |
Matsumura H et al. | [Antagonism of collagen-induced ECG changes in rats by a thromboxane synthetase inhibitor, CV-4151]. | 1986 | Nippon Yakurigaku Zasshi | pmid:3755113 |
Miller MJ et al. | Compartmental prostaglandin release by angiotensin II and arginine-vasopressin in rabbit isolated perfused kidneys. | 1986 | Eur. J. Pharmacol. | pmid:3456305 |
Fukushima M and Kobayashi T | Effects of thromboxane synthase inhibition on air emboli lung injury in sheep. | 1986 | J. Appl. Physiol. | pmid:3755131 |
Fleming WH et al. | Serum concentrations of prostacyclin and thromboxane in children before, during, and after cardiopulmonary bypass. | 1986 | J. Thorac. Cardiovasc. Surg. | pmid:3755198 |
Calò L et al. | Arachidonic acid metabolites in a nephroblastoma associated with paraneoplastic hypercalcemia. | 1986 | Prostaglandins | pmid:3020618 |
Westlund P et al. | Identification of 11-dehydro-TXB2 as a suitable parameter for monitoring thromboxane production in the human. | 1986 | Prostaglandins | pmid:3755250 |
Pattison A et al. | The in vitro effect of amrinone on thromboxane B2 synthesis in human whole blood. | 1986 | Thromb. Res. | pmid:3755259 |
Tarayre JP et al. | Exudative, cellular and humoral reactions to platelet-activating factor (PAF-acether) in the pleural cavity of rats. | 1986 | Eur. J. Pharmacol. | pmid:3755401 |
Granström E | Methodology in prostaglandin and thromboxane assay. | 1986 | Prog. Lipid Res. | pmid:3321087 |
Neri Serneri GG et al. | Enhanced peripheral vasoconstrictor response and increased thromboxane A2 synthesis after the cold pressor test in patients with angina at rest. | 1986 | Circulation | pmid:3948351 |
Dupont J et al. | Eicosanoid synthesis in Alagille syndrome. | 1986 | N. Engl. J. Med. | pmid:3951499 |
Yanni JM and Smith WL | Intravenous SRS-induced increases in tracheal mucous gel layer thickness: evidence for thromboxane involvement. | 1986 | Prostaglandins | pmid:3952339 |
Madden MC et al. | Effect of hypoxia on prostacyclin production in cultured pulmonary artery endothelium. | 1986 | Prostaglandins | pmid:3094092 |
Manny J et al. | Pulmonary and systemic consequences of localized acid aspiration. | 1986 | Surg Gynecol Obstet | pmid:3952619 |
Fischer S et al. | The prostacyclin/thromboxane balance is favourably shifted in Greenland Eskimos. | 1986 | Prostaglandins | pmid:3025932 |
O'Connor KM et al. | Effect of thromboxane synthetase inhibition on vulnerability to ventricular arrhythmia following coronary occlusion. | 1986 | Am. Heart J. | pmid:3953390 |
Del Principe D et al. | Vitamin E consumption by human blood platelets activated by latex particles. | 1986 | Am. J. Hematol. | pmid:3953557 |
Shohami E and Feuerstein G | T-2 toxemia and brain prostaglandins. | 1986 | Prostaglandins | pmid:3457405 |
Sinzinger H et al. | Platelet half-life, plasma thromboxane B2 and circulating endothelial-cells in peripheral vascular disease. | 1986 | Angiology | pmid:3954150 |
Noonan TC and Malik AB | Pulmonary vascular response to leukotriene D4 in unanesthetized sheep: role of thromboxane. | 1986 | J. Appl. Physiol. | pmid:3957828 |
Korth R et al. | Unsaturated platelet-activating factor: influence on aggregation, serotonin release and thromboxane synthesis of human thrombocytes. | 1986 | Thromb. Res. | pmid:3961742 |
Kumlin M and Granström E | Radioimmunoassay for 11-dehydro-TXB2: a method for monitoring thromboxane production in vivo. | 1986 | Prostaglandins | pmid:3823488 |
di Minno G et al. | The binding of fibrinogen to platelets in diabetes mellitus. | 1986 | Wien. Klin. Wochenschr. | pmid:3010580 |
Foegh ML et al. | Coronary artery thrombosis and elevated urine immunoreactive thromboxane B2. | 1986 | Prostaglandins | pmid:3823490 |
Kiviniemi H and Rämo OJ | The behaviour of prostanoids during the course of acute experimental pancreatitis in rats. | 1986 | Res Exp Med (Berl) | pmid:3823620 |
Cizmeci G | In vivo effects of defibrotide on platelet c-AMP and blood prostanoid levels. | 1986 | Haemostasis | pmid:3011617 |
Burghuber OC et al. | Inhibition of acetylcholine-induced bronchoconstriction in asthmatics by nifedipine. | 1986 | Respiration | pmid:3823637 |
Rouse IL et al. | Nutrient intake, blood pressure, serum and urinary prostaglandins and serum thromboxane B2 in a controlled trial with a lacto-ovo-vegetarian diet. | 1986 | J. Hypertens. | pmid:3011891 |
Prosdocimi M et al. | Action of AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonylmet hox y coumarin) on human platelets in vitro. | 1986 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:3012375 |
Riess H et al. | Thromboxane receptor blockade versus cyclooxigenase inhibition: antiplatelet effects in patients. | 1986 | Thromb. Res. | pmid:3012819 |
Steinhauer HB and Schollmeyer P | Prostaglandin-mediated loss of proteins during peritonitis in continuous ambulatory peritoneal dialysis. | 1986 | Kidney Int. | pmid:3457982 |
Altman R et al. | Synergistic actions of PAF-acether and sodium arachidonate in human platelet aggregation. 1. Studies in normal human platelet rich plasma. | 1986 | Thromb. Res. | pmid:3014677 |
Simon MF et al. | Selective inhibition of human platelet phospholipase A2 by buffering cytoplasmic calcium with the fluorescent indicator quin 2. Evidence for different calcium sensitivities of phospholipases A2 and C. | 1986 | Biochim. Biophys. Acta | pmid:3080024 |
Purchase M et al. | Physiological concentrations of epinephrine potentiate thromboxane A2 release from platelets in the isolated rat heart. | 1986 | Circ. Res. | pmid:3080260 |
Sokolov EI et al. | [Disorders in the status of the vessel-thrombocyte and plasma links of the hemostatic system in the pathogenesis of disseminated intravascular coagulation in ischemic heart disease]. | 1986 | Kardiologiia | pmid:3784270 |
Friesinger GC and Robertson RM | Vasospastic angina: a continuing search for mechanism(s). | 1986 | J. Am. Coll. Cardiol. | pmid:3510238 |
Goldblum SE et al. | Streptococcus pneumoniae-induced alterations in levels of circulating thromboxane and prostacyclin: dissociation from granulocytopenia, thrombocytopenia, and pulmonary leukostasis. | 1986 | J. Infect. Dis. | pmid:3510262 |
Hamilton J et al. | Platelet interaction with a pancreatic ascites tumor. | 1986 | Am. J. Pathol. | pmid:3510553 |
DiBenedetto FE and Bito LZ | Transport of prostaglandins and other eicosanoids by the choroid plexus: its characterization and physiological significance. | 1986 | J. Neurochem. | pmid:3517230 |
Bucchi F et al. | Effects of 1 gram oral or intravenous aspirin on urinary excretion of thromboxane B2 and 6-keto-PGF1 alpha in healthy subjects. | 1986 | Prostaglandins | pmid:3103169 |
Kintner DB et al. | Cerebral vascular resistance following platelet and leukocyte removal from perfusate. | 1986 | J. Cereb. Blood Flow Metab. | pmid:3944216 |
Patrono C et al. | Estimated rate of thromboxane secretion into the circulation of normal humans. | 1986 | J. Clin. Invest. | pmid:3944270 |
Emms H and Lewis GP | The roles of prostaglandin endoperoxides, thromboxane A2 and adenosine diphosphate in collagen-induced aggregation in man and the rat. | 1986 | Br. J. Pharmacol. | pmid:3082399 |
Butler KD et al. | The effects of modulation of prostanoid metabolism on the thoracic platelet accumulation induced by intravenous administration of collagen in the guinea-pig. | 1986 | Thromb. Haemost. | pmid:3105104 |