MeSH term | MeSH ID | Detail |
---|---|---|
Acute Coronary Syndrome | D054058 | 11 associated lipids |
Airway Remodeling | D056151 | 3 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Halushka PV et al. | Insulin and arachidonic acid metabolism in diabetes mellitus. | 1985 | Metab. Clin. Exp. | pmid:3934501 |
Kimura Y et al. | Effects of stilbenes on arachidonate metabolism in leukocytes. | 1985 | Biochim. Biophys. Acta | pmid:3922423 |
Packham MA et al. | Duration of the effect of aspirin on the synthesis of thromboxane by density subpopulations of rabbit platelets stimulated with thrombin. | 1985 | Blood | pmid:3926022 |
Cattaneo M et al. | Human platelet aggregation and release reaction induced by platelet activating factor (PAF-acether)--effects of acetylsalicylic acid and external ionized calcium. | 1985 | Thromb. Haemost. | pmid:3927505 |
Aitokallio-Tallberg A et al. | Prostacyclin and thromboxane in breast cancer: relationship between steroid receptor status and medroxyprogesterone acetate. | 1985 | Br. J. Cancer | pmid:2986666 |
Callahan KS et al. | Enhancement of the antiaggregatory activity of prostacyclin by propranolol in human platelets. | 1985 | Circulation | pmid:2986877 |
Schmitz JM et al. | Vascular prostaglandin and thromboxane production in a canine model of myocardial ischemia. | 1985 | Circ. Res. | pmid:3926340 |
Apprill P et al. | Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors. | 1985 | Circulation | pmid:2988822 |
Friedrich T et al. | Follow-up of prostaglandin plasma levels after acute myocardial infarction. | 1985 | Am. Heart J. | pmid:3880994 |
Wilson TW and Tan LK | Low plasma renin activity in diabetes. Relation to urine prostaglandin excretion. | 1985 | Diabetes | pmid:3881302 |
Longenecker GL et al. | Kinetics of ibuprofen effect on platelet and endothelial prostanoid release. | 1985 | Clin. Pharmacol. Ther. | pmid:3882308 |
de Lorgeril M et al. | Acute influence of cigarette smoke in platelets, catecholamines and neurophysins in the normal conditions of daily life. | 1985 | Eur. Heart J. | pmid:2937635 |
Lelcuk S et al. | Prostacyclin and thromboxane A2 moderate postischemic renal failure. | 1985 | Surgery | pmid:3895535 |
Paajanen H and Kormano M | Prostacyclin (PGI2) and thromboxane (TXA2) levels during intravenous contrast medium administration in CT. | 1985 | Eur J Radiol | pmid:3896802 |
Yui Y et al. | A new stable prostacyclin analogue OP41483 (15-cyclopentyl-omega-pentanor-5(E)-carbacyclin). | 1985 | Jpn. Circ. J. | pmid:3897597 |
Codde JP and Beilin LJ | Dietary fish oil prevents dexamethasone induced hypertension in the rat. | 1985 | Clin. Sci. | pmid:3905217 |
Martin JL et al. | Effect of high dose aspirin on coronary hemodynamics during pacing-induced myocardial ischemia. | 1985 | J. Am. Coll. Cardiol. | pmid:3968305 |
De Caterina R et al. | Inhibition of platelet aggregation and thromboxane B2 production during aspirin treatment: dependence on the dose of the aggregating agent. | 1985 | Thromb. Res. | pmid:3975876 |
Cook JA et al. | Exchange transfusions in rats with a perfluorated blood substitute: effect on thromboxane B2 levels during endotoxemia. | 1985 | Circ. Shock | pmid:3978769 |
Schrör K et al. | [Inhibition of platelet aggregation and thromboxane formation by the calcium antagonist nisoldipine following a single oral dose of 10 mg. A double-blind study in healthy probands]. | 1985 | Klin. Wochenschr. | pmid:3838352 |
Bult H et al. | Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid. | 1985 | Br. J. Pharmacol. | pmid:3838489 |
Tada M et al. | Augmented thromboxane A2 generation and efficacy of its blockade in acute myocardial infarction. | 1985 | Int. J. Cardiol. | pmid:4040500 |
Wargovich T et al. | Reduction in blood flow in normal and narrowed coronary arteries of dogs by leukotriene C4. | 1985 | J. Am. Coll. Cardiol. | pmid:4045029 |
Elliott GR et al. | Arachidonic acid, an in vivo inhibitor of carrageenin induced granulomas in the rat. | 1985 | Eur. J. Pharmacol. | pmid:2988985 |
Feuerstein G et al. | Effects of nafazatrom on cardiovascular, sympathetic, and endocrine responses to hemorrhagic shock in conscious rats. | 1985 | Circ. Shock | pmid:3841032 |
Cerletti C et al. | Aspirin kinetics and inhibition of platelet thromboxane generation-relevance for a solution of the "aspirin dilemma". | 1985 | Thromb. Haemost. | pmid:4049312 |
Dejana E et al. | Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy. | 1985 | Proc. Soc. Exp. Biol. Med. | pmid:3841210 |
Fiedler VB et al. | The effects of nafazatrom in an acute occlusion-reperfusion model of canine myocardial injury. | 1985 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:3841382 |
Palmer RM and Salmon JA | Comparison of the effects of some compounds on human neutrophil degranulation and leukotriene B4 and thromboxane B2 synthesis. | 1985 | Biochem. Pharmacol. | pmid:2986647 |
Fisher M et al. | Selective thromboxane inhibition: a new approach to antiplatelet therapy. | 1984 Sep-Oct | Stroke | pmid:6474531 |
Uderman HD et al. | Thromboxane synthetase inhibitor UK38,485 lowers blood pressure in the adult spontaneously hypertensive rat. | 1984 Sep-Oct | J. Cardiovasc. Pharmacol. | pmid:6209508 |
Sturm M et al. | The measurement of plasma thromboxane B2 and the effect of smoking. | 1984 Nov-Dec | Clin. Exp. Pharmacol. Physiol. | pmid:6536421 |
Menitove JE et al. | Use of prostacyclin to inhibit activation of platelets during preparation of platelet concentrates. | 1984 Nov-Dec | Transfusion | pmid:6390814 |
Tanabe M et al. | Inhibition of coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion by 2-phenylaminoadenosine (CV-1808) in anesthetized dogs. | 1984 May-Jun | J. Cardiovasc. Pharmacol. | pmid:6202970 |
Laustiola K et al. | Exercise-induced increase in plasma arachidonic acid and thromboxane B2 in healthy men: effect of beta-adrenergic blockade. | 1984 May-Jun | J. Cardiovasc. Pharmacol. | pmid:6202971 |
Egg D | Concentrations of prostaglandins D2, E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 in synovial fluid from patients with inflammatory joint disorders and osteoarthritis. | 1984 Mar-Apr | Z Rheumatol | pmid:6730731 |
De Caterina R et al. | Thromboxane-B2 generation during ex-vivo platelet aggregation. | 1984 Jul-Sep | J. Nucl. Med. Allied Sci. | pmid:6530623 |
Buchanan MR and Hirsh J | Effect of aspirin and salicylate on platelet-vessel wall interactions in rabbits. | 1984 Jul-Aug | Arteriosclerosis | pmid:6380468 |
Paajanen H et al. | Modification of platelet aggregation and thromboxane synthesis by intravascular contrast media. | 1984 Jul-Aug | Invest Radiol | pmid:6434489 |
MacNab MW et al. | The effects of a new thromboxane synthetase inhibitor, CGS-13080, in man. | 1984 Feb-Mar | J Clin Pharmacol | pmid:6371062 |
Marks JG et al. | Contact urticaria and airway obstruction from carbonless copy paper. | 1984 Aug 24-31 | JAMA | pmid:6235381 |
Sheehan DV et al. | Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. | 1984 | J Clin Psychopharmacol | pmid:6142907 |
Barnett AH et al. | Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes. | 1984 | Lancet | pmid:6145027 |
Schenkelaars EJ and Bonta IL | Beta 2-adrenoceptor agonists reverse the leukotriene C4-induced release response of macrophages. | 1984 | Eur. J. Pharmacol. | pmid:6151905 |
Giani E et al. | Sex differences in platelet thromboxane and arterial prostacyclin production in control and n-6 fatty acid supplemented rats. | 1984 | Prostaglandins | pmid:6441187 |
Patrignani P et al. | Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism. | 1984 | J. Pharmacol. Exp. Ther. | pmid:6537977 |
Vesterqvist O and Gréen K | Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions. | 1984 | Prostaglandins | pmid:6539491 |
McCluskey ER et al. | In vivo inhibition of thromboxane synthetase in infarcted canine myocardium. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6539597 |
Chan PK and Gentry PA | Inhibition of bovine platelet function by T-2 toxin, HT-2 toxin, diacetoxyscirpenol and deoxynivalenol. | 1984 | Food Chem. Toxicol. | pmid:6540739 |
Moufarrij NA et al. | Thromboxane synthetase inhibition in acute focal cerebral ischemia in cats. | 1984 | J. Neurosurg. | pmid:6542131 |
Hock CE and Lefer AM | Beneficial effect of a thromboxane synthetase inhibitor in traumatic shock. | 1984 | Circ. Shock | pmid:6542462 |
Ito T et al. | Selective thromboxane synthetase inhibitor and ischemic heart disease. | 1984 | Biomed. Biochim. Acta | pmid:6542777 |
Brown CG and Poyser NL | Studies on the control of prostaglandin production by the hypothalamus in relation to LH release in the rat. | 1984 | J. Endocrinol. | pmid:6593408 |
Okazaki K et al. | [Measurement of prostaglandins in human bile juice]. | 1984 | Nihon Shokakibyo Gakkai Zasshi | pmid:6549033 |
Garcia-Szabo RR et al. | Comparison of alpha- and gamma-thrombin on lung fluid balance in anesthetized sheep. | 1984 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6549181 |
Takeda H et al. | [Comparison of centrifugal pump (bio pump) with roller pump: clinical study]. | 1984 | Kyobu Geka | pmid:6549344 |
Chen LS et al. | Plasma concentrations of 6-keto-prostaglandin F1 alpha, thromboxane B2 and platelet aggregation in patients with essential hypertension. | 1984 | Jpn Heart J | pmid:6549401 |
Ishihara Y et al. | [Cigarette smoking and lung metabolism--effect of cigarette smoking on blood levels of 6-keto PGF1 alpha, thromboxane B2 and lipoperoxide in healthy volunteers]. | 1984 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:6549510 |
Watanabe J et al. | Effect of vitamin E on platelet aggregation in diabetes mellitus. | 1984 | Thromb. Haemost. | pmid:6495252 |
Stahl RA et al. | Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. | 1984 | Am. J. Physiol. | pmid:6507633 |
Kääpä P et al. | Thromboxane B2 production by fetal and neonatal platelets: effect of idiopathic respiratory distress syndrome and birth asphyxia. | 1984 | Pediatr. Res. | pmid:6472947 |
Gross S and Worthington-White DA | The effects of PGF2 alpha, PGI2, and TxB2 on human CFU-C in healthy and leukemic patients. | 1984 | Am. J. Hematol. | pmid:6372442 |
D'Angelo A et al. | Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. | 1984 | Eur. J. Clin. Invest. | pmid:6428908 |
Essien EM et al. | Blood changes and enhanced thromboxane and 6-keto prostaglandin F1 alpha production in experimental acute Plasmodium bergei infection in hamsters. | 1984 | Thromb. Haemost. | pmid:6388013 |
Mäkäräinen L and Ylikorkala O | Amniotic fluid 6-keto-prostaglandin F1 alpha and thromboxane B2 during labor. | 1984 | Am. J. Obstet. Gynecol. | pmid:6388335 |
Baughman RP et al. | Prostaglandins and thromboxanes in the bronchoalveolar lavage fluid: possible immunoregulation in sarcoidosis. | 1984 | Am. Rev. Respir. Dis. | pmid:6388445 |
DiSesa VJ et al. | Disadvantages of prostacyclin infusion during cardiopulmonary bypass: a double-blind study of 50 patients having coronary revascularization. | 1984 | Ann. Thorac. Surg. | pmid:6388516 |
Takeda H et al. | [Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation]. | 1984 | Kyobu Geka | pmid:6389949 |
Jackson EK et al. | Attenuation of noradrenergic neurotransmission by the thromboxane synthetase inhibitor, UK 38,485. | 1984 | Life Sci. | pmid:6330486 |
Kawai C | New horizons in cardiology. | 1984 | Int. J. Cardiol. | pmid:6334040 |
McGoon MD and Vanhoutte PM | Aggregating platelets contract isolated canine pulmonary arteries by releasing 5-hydroxytryptamine. | 1984 | J. Clin. Invest. | pmid:6470141 |
Huang HC | Release of slow reacting substance from the guinea-pig lung by phospholipases A2 of Vipera russelli snake venom. | 1984 | Toxicon | pmid:6206608 |
Brunner D et al. | Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus. | 1984 | Clin Ther | pmid:6206948 |
Gragnoli G et al. | [Effects of ticlopidine on the plasma levels of beta-thromboglobulin and thromboxane B2 in types 1 and 2 diabetics]. | 1984 | Minerva Med. | pmid:6207465 |
Rachmilewitz D and Karmeli F | Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. | 1984 | Eur. J. Pharmacol. | pmid:6152213 |
Stock JL and Coderre JA | Calcitonin enhances production of prostaglandins by stimulated human monocytes. | 1984 | Prostaglandins | pmid:6087420 |
Yui Y et al. | Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. | 1984 | Circulation | pmid:6434196 |
Jackson CA et al. | Near-normal glycaemic control does not correct abnormal platelet reactivity in diabetes mellitus. | 1984 | Clin. Sci. | pmid:6434224 |
Coker SJ and Parratt JR | The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds. | 1984 | J. Mol. Cell. Cardiol. | pmid:6366241 |
Stuart MJ et al. | Effects of hyperoxia and hypoxia on vascular prostacyclin formation in vitro. | 1984 | Pediatrics | pmid:6435087 |
Higashihara M et al. | Interaction of Solanum tuberosum agglutinin with human platelets. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6732807 |
Miyazaki H et al. | Microdetermination of prostaglandins and thromboxane B2 by capillary gas chromatography and negative ion chemical ionization mass spectrometry. | 1984 | J. Chromatogr. | pmid:6736155 |
Kelton JG et al. | A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation. | 1984 | Thromb. Res. | pmid:6740573 |
Ylikorkala O et al. | Peritoneal fluid prostaglandins in endometriosis, tubal disorders, and unexplained infertility. | 1984 | Obstet Gynecol | pmid:6232475 |
Morrison AR and Crowley JR | Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla. | 1984 | Arch. Biochem. Biophys. | pmid:6437329 |
Foegh ML et al. | Monitoring of rat heart allograft rejection by urinary thromboxane. | 1984 | Transplant. Proc. | pmid:6390873 |
Willerson JT et al. | Conversion from chronic to acute coronary artery disease: speculation regarding mechanisms. | 1984 | Am. J. Cardiol. | pmid:6391133 |
Fareed J et al. | Molecular markers of contrast media-induced adverse reactions. | 1984 | Semin. Thromb. Hemost. | pmid:6393351 |
Takeda H et al. | [Alternations in coagulation and fibrinolysis associated with extracorporeal circulation--the role of vasoactive prostanoids]. | 1984 | Rinsho Kyobu Geka | pmid:6395300 |
Tada M et al. | Reduction of prostacyclin synthesis as a possible cause of transient flow reduction in a partially constricted canine coronary artery. | 1984 | J. Mol. Cell. Cardiol. | pmid:6398370 |
Ylikorkala O | Prostanoids in gynaecology. | 1984 | Ann. Clin. Res. | pmid:6398666 |
Vapaatalo H et al. | Prostanoids in blood pressure regulation and their role in the blood pressure lowering effects induced by changes in dietary fats. | 1984 | Ann. Clin. Res. | pmid:6398981 |
Wang JP et al. | XC 386: a new antiplatelet agent. | 1984 | Thromb. Res. | pmid:6438827 |
Fuller RW et al. | Dexamethasone inhibits the production of thromboxane B2 and leukotriene B4 by human alveolar and peritoneal macrophages in culture. | 1984 | Clin. Sci. | pmid:6091982 |
Gal D et al. | Effect of radiation on prostaglandin production by human bowel in vitro. | 1984 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:6588048 |
Oglesby TD and Gorman RR | The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. | 1984 | Biochim. Biophys. Acta | pmid:6424715 |
Eldor A et al. | The effect of oral administration of dipyrone on the capacity of blood platelets to synthesize thromboxane A2 in man. | 1984 | Eur. J. Clin. Pharmacol. | pmid:6723755 |
Cerletti C et al. | Plasma levels of salicylate and aspirin in healthy volunteers: relevance to drug interaction on platelet function. | 1984 | J. Lab. Clin. Med. | pmid:6726057 |
Anderson CB et al. | Renal thromboxane synthesis in excised kidney distal to renovascular lesions. | 1984 | JAMA | pmid:6726983 |
Grignani G et al. | Activation of platelet prostaglandin biosynthesis pathway during neoplastic cell-induced platelet aggregation. | 1984 | Thromb. Res. | pmid:6729776 |