MeSH term | MeSH ID | Detail |
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Acute Coronary Syndrome | D054058 | 11 associated lipids |
Airway Remodeling | D056151 | 3 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mäkilä UM et al. | Relation between umbilical prostacyclin production and blood-flow in the fetus. | 1983 | Lancet | pmid:6132081 |
Thorngren M et al. | Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid. | 1983 | Lancet | pmid:6133107 |
Drake TS et al. | Peritoneal fluid prostanoids in unexplained infertility. | 1983 | Am. J. Obstet. Gynecol. | pmid:6614085 |
Stenson WF and Lobos E | Inhibition of platelet thromboxane synthetase by sulfasalazine. | 1983 | Biochem. Pharmacol. | pmid:6135423 |
Chang J et al. | Effects of thiazinamium chloride, promethazine and chlorpromazine on thromboxane B2 synthesis, phagocytosis and respiratory burst by rat alveolar macrophages. | 1983 | Biochem. Pharmacol. | pmid:6138040 |
Deckmyn H et al. | Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. | 1983 | Biochem. Pharmacol. | pmid:6578796 |
Saldeen P et al. | Increased synthesis of thromboxane B2 and 6-keto-PGF1 alpha in hand veins from patients with deep venous thrombosis. | 1983 | Thromb. Res. | pmid:6658723 |
Goetzl EJ et al. | Enhancement of human neutrophil adherence by synthetic leukotriene constituents of the slow-reacting substance of anaphylaxis. | 1983 | Immunology | pmid:6193056 |
McManus LM et al. | Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. | 1983 | Immunopharmacology | pmid:6832960 |
Martin JL et al. | Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. | 1983 | J. Am. Coll. Cardiol. | pmid:6833660 |
Ferraris VA and Swanson E | Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. | 1983 | Surg Gynecol Obstet | pmid:6836459 |
Margotat A et al. | A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. | 1983 | J Pharmacol Methods | pmid:6843139 |
Rotmensch HH et al. | Plasma platelet products and exercise-induced myocardial ischemia. | 1983 | J. Lab. Clin. Med. | pmid:6854135 |
Hamelin SS and Chan AC | Modulation of platelet thromboxane and malonaldehyde by dietary vitamin E and linoleate. | 1983 | Lipids | pmid:6855486 |
De Clerck F et al. | Platelet activation by endogenous 5-hydroxytryptamine and histamine released by mast cell degranulation with compound 48/80 in the rat. | 1983 | Agents Actions | pmid:6858790 |
Preston FE | Aspirin, prostaglandins, and peripheral gangrene. | 1983 | Am. J. Med. | pmid:6859070 |
Palmer RM and Salmon JA | Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187. | 1983 | Immunology | pmid:6309653 |
Winter M et al. | Synthesis of thromboxane B2 in uraemia and the effects of dialysis. | 1983 | Thromb. Res. | pmid:6868024 |
Menys VC and Davies JA | Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. | 1983 | Clin. Sci. | pmid:6190604 |
Hartung HP and Toyka KV | Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. | 1983 | Eur. J. Pharmacol. | pmid:6191998 |
Tanganelli I et al. | [Thromboxane, beta-thromboglobulin and the degree of blood sugar control in type 1 diabetes mellitus]. | 1983 | Boll. Soc. Ital. Biol. Sper. | pmid:6194801 |
Capodicasa G et al. | Platelet thromboxane formation and BTG levels after intensive charcoal HP in uremics or regular hemodialytic treatment (RHT). | 1983 | Int J Artif Organs | pmid:6195116 |
Ditter H et al. | Effects of prostacyclin during cardiopulmonary bypass in men on plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2, 6-keto-prostaglandin F1 alpha and heparin. | 1983 | Thromb. Res. | pmid:6197766 |
Lismonde M et al. | [The presence of 6-oxo-PGF1alpha and thromboxane B2 in peritoneal exudates released by iota-carrageenan in the rat]. | 1983 | Arch. Int. Physiol. Biochim. | pmid:6198994 |
Tolman EL and Fuller BL | Inhibition of thromboxane synthesis in guinea pig lung and human platelets by clotrimazole and other imidazole antifungals. | 1983 | Biochem. Pharmacol. | pmid:6316985 |
Wientroub S et al. | Changes in tissue concentration of prostaglandins during endochondral bone differentiation. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6582850 |
Salmon JA et al. | The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation. | 1983 | J. Pharm. Pharmacol. | pmid:6141244 |
Stimler NP and O'Flaherty JT | Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. | 1983 | Am. J. Pathol. | pmid:6624879 |
Stratta P et al. | Warning: platelet factor 4, beta-thromboglobulin and thromboxane in donor's plasma units. | 1983 | Thromb. Haemost. | pmid:6189235 |
McDaniel HG et al. | Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction. | 1983 | Am. J. Cardiol. | pmid:6416046 |
de Kergommeaux BD et al. | Effects of ASA on thromboxane and prostacyclin synthesis by rabbit aorta and pulmonary artery. | 1983 | Prostaglandins Leukot Med | pmid:6410417 |
Boughton-Smith NK et al. | Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa. | 1983 | Gut | pmid:6416934 |
Ylikorkala O | Prostacyclin and thromboxane during human pregnancy. | 1983 | Acta Obstet Gynecol Scand Suppl | pmid:6344543 |
Qvist R and Larkins RG | Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects. | 1983 | Diabetes | pmid:6345241 |
Newman JH et al. | Effects of 100% oxygen on lung vascular function in awake sheep. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6345493 |
Eldor A et al. | Effects of dipyrone on prostaglandin production by human platelets and cultured bovine aortic endothelial cells. | 1983 | Thromb. Haemost. | pmid:6346571 |
Menys VC and Davies JA | Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. | 1983 | Thromb. Haemost. | pmid:6346575 |
Reeves WC et al. | The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. | 1983 | Prostaglandins Leukot Med | pmid:6348800 |
Aznavoorian SA et al. | Prostacyclin inhibits 5-hydroxytryptamine release but stimulates thromboxane synthesis during cardiopulmonary bypass. | 1983 | Prostaglandins | pmid:6348886 |
Buchanan MR et al. | The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. | 1983 | Thromb. Res. | pmid:6221436 |
Kaar ML et al. | Prostacyclin and thromboxane in diabetic children. | 1983 | Prostaglandins Leukot Med | pmid:6351104 |
Yamamoto S et al. | Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221523 |
Fischer S et al. | The influence of selective thromboxane synthetase inhibition with a novel imidazole derivative, UK-38,485, on prostanoid formation in man. | 1983 | Circulation | pmid:6352080 |
Weerasekera DA et al. | Chemiluminescence immunoassay of thromboxane B2. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221524 |
Davi' G et al. | Platelet activation after adrenergic stimulation in hypertensive patients: effects of acebutolol. | 1983 | Eur. Heart J. | pmid:6352266 |
Ito T et al. | Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221531 |
FitzGerald GA et al. | Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221534 |
FitzGerald GA et al. | Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. | 1983 | J. Clin. Invest. | pmid:6355181 |
Jouve R et al. | [Plasma thromboxane B2 and capacity of the aorta to produce prostacyclin in arteriopathies of the lower extremities]. | 1983 | J Mal Vasc | pmid:6355348 |
Mehta J et al. | Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581. | 1983 | Prostaglandins Leukot Med | pmid:6356153 |
Henriksen RA and Brotherton AF | Evidence that activation of platelets and endothelium by thrombin involves distinct sites of interaction. Studies with the dysthrombin, Thrombin Quick I. | 1983 | J. Biol. Chem. | pmid:6358210 |
Kaliman J et al. | [Venous prostacycline synthesis and plasma thromboxane B2 after low-dose aspirin]. | 1983 | Wien. Klin. Wochenschr. | pmid:6359724 |
Kiff PS et al. | Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. | 1983 | Br J Clin Pharmacol | pmid:6681708 |
Hutton I et al. | Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease. | 1983 | Br J Clin Pharmacol | pmid:6681709 |
Feddersen CO et al. | Leukotriene E4 causes pulmonary vasoconstriction, not inhibited by meclofenamate. | 1983 | Prostaglandins | pmid:6098932 |
Zijlstra FJ et al. | Thrombotic thrombocytopenic purpura and plasma thromboxane B2 levels. | 1983 | Thromb. Res. | pmid:6684333 |
Lianos EA et al. | Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics. | 1983 | J. Clin. Invest. | pmid:6685136 |
Wynalda MA et al. | Sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate (U-63557A), a new, selective thromboxane synthase inhibitor: intravenous and oral pharmacokinetics in dogs and correlations with ex situ thromboxane B2 production. | 1983 | Prostaglandins | pmid:6685888 |
McDonald JW et al. | Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep. | 1983 | Circ. Res. | pmid:6687354 |
Randall MJ and Wilding RI | Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01). | 1983 | Br J Clin Pharmacol | pmid:6687429 |
Bruckner G et al. | Dietary trilinoelaidate: effects on hematological parameters, serum eicosanoids and tissue fatty acid composition in rats. | 1983 | J. Nutr. | pmid:6687476 |
Bessin P et al. | Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs. | 1983 | Eur. J. Pharmacol. | pmid:6687572 |
Ingerman-Wojenski CM et al. | Early morphological changes in the endothelium of a peripheral artery of rabbits fed an atherogenic diet. | 1983 | Exp. Mol. Pathol. | pmid:6687574 |
Schumacher WA and Lucchesi BR | Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6418881 |
Morita I et al. | Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. | 1983 | J. Biol. Chem. | pmid:6309794 |
Hartung HP and Toyka KV | Tuftsin stimulates the release of oxygen radicals and thromboxane from macrophages. | 1983 | Immunol. Lett. | pmid:6687720 |
Westwick J et al. | Platelet activation during steady state sickle cell disease. | 1983 | J Med | pmid:6224876 |
Kurata M | [Relation between mouse peritoneal macrophage functions and prostaglandins]. | 1983 | Rinsho Byori | pmid:6689184 |
Maguire ED and Wallis RB | In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. | 1983 | Thromb. Res. | pmid:6689221 |
Zijlstra FJ and Vincent JE | Comparison of the determination of thromboxane A2 by bioassay on the rabbit mesenteric artery and in the form of TxB2 by radioimmunoassay. | 1983 | J Pharmacol Methods | pmid:6632924 |
Bryant RW and Hwang DH | Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. | 1983 | Prostaglandins | pmid:6419285 |
Wilson L | Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. | 1983 | Prostaglandins | pmid:6635211 |
Sanders TA and Hochland MC | A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. | 1983 | Br. J. Nutr. | pmid:6639916 |
Mehta JL | Prostaglandins: regulatory role in cardiovascular system and implications in ischemic heart disease. | 1983 | Int. J. Cardiol. | pmid:6642760 |
Mathieson MA et al. | Ischemia of the limb stimulates thromboxane production and myocardial depression. | 1983 | Surg Gynecol Obstet | pmid:6648769 |
Barrett PA and Butler KD | Shortening of platelet survival by induced hypercholesterolaemia in rabbits and its prolongation by anagrelide. | 1983 | Thromb. Haemost. | pmid:6648889 |
Robinson C and Hoult JR | Thromboxane A2 analogues inhibit the metabolism of thromboxane B2 in perfused guinea-pig lung. | 1983 | Biochim. Biophys. Acta | pmid:6652102 |
Higgs GA et al. | The source of thromboxane and prostaglandins in experimental inflammation. | 1983 | Br. J. Pharmacol. | pmid:6652359 |
Anton RF et al. | In vivo regional levels of PGE and thromboxane in mouse brain: effect of decapitation, focused microwave fixation, and indomethacin. | 1983 | Prostaglandins | pmid:6658001 |
Mahoney D et al. | Influence of dietary polyunsaturated fatty acids on renal & aortic prostaglandin synthesis in 1 kidney 1 clip Goldblatt hypertensive rats. | 1983 | Prostaglandins | pmid:6658002 |
Martin JF et al. | The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration. | 1983 | Thromb. Res. | pmid:6658722 |
Cohen RA et al. | 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries. | 1983 | Am. J. Physiol. | pmid:6660308 |
Socini A et al. | Fish oil administration as a supplement to a corn oil containing diet affects arterial prostacyclin production more than platelet thromboxane formation in the rat. | 1983 | Prostaglandins | pmid:6310702 |
Karmali RA et al. | Prostaglandins in breast cancer: relationship to disease stage and hormone status. | 1983 | Br. J. Cancer | pmid:6416285 |
Gethmann U et al. | Effect of catecholestrogens on prostaglandin release by rat pituitaries superfused in vitro. | 1983 | Arch. Gynecol. | pmid:6320749 |
Ouwendijk RJ et al. | Raised plasma thromboxane B2 levels in alcoholic liver disease. | 1983 | Prostaglandins Leukot Med | pmid:6573682 |
Hornych A et al. | Thromboxane B2 in borderline and essential hypertensive patients. | 1983 | Prostaglandins Leukot Med | pmid:6573683 |
Flynn JT et al. | Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. | 1983 | Prostaglandins Leukot Med | pmid:6573688 |
Patel K and Bakhle YS | Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. | 1983 | Prostaglandins Leukot Med | pmid:6573689 |
Davì G et al. | Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. | 1983 | Prostaglandins Leukot Med | pmid:6573692 |
Lieb J et al. | Elevated levels of prostaglandin E2 and thromboxane B2 in depression. | 1983 | Prostaglandins Leukot Med | pmid:6574523 |
Coceani F et al. | Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. | 1983 | Am. J. Physiol. | pmid:6574712 |
Viinikka L et al. | Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects. | 1983 | Prostaglandins Leukot Med | pmid:6576385 |
Fukumoto S and Tanaka K | Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. | 1983 | Prostaglandins Leukot Med | pmid:6576388 |
Kinney EL et al. | Mechanism of action of amrinone: role of thromboxane synthetase inhibition. | 1983 | Prostaglandins Leukot Med | pmid:6576389 |
Hawkey CJ et al. | Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease. | 1983 | Gut | pmid:6578172 |
Zijlstra FJ et al. | Separation of the two components of the contractile activity of leukotriene C4 on the guinea pig lung parenchymal strip. | 1983 | Prostaglandins Leukot Med | pmid:6578519 |
Mahoney DP et al. | Radioimmunoassay of prostaglandins and thromboxane B2 in extracted and unextracted urine and serum using an iodinated ligand. | 1983 | Prostaglandins Leukot Med | pmid:6579570 |
Güllner HG et al. | Renal thromboxane excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin treatment. | 1983 | Prostaglandins Leukot Med | pmid:6580653 |
Carr BR et al. | Prostaglandin secretion by the neocortex and fetal zones of the human fetal adrenal gland. | 1983 | J. Clin. Endocrinol. Metab. | pmid:6313732 |