MeSH term | MeSH ID | Detail |
---|---|---|
Acute Coronary Syndrome | D054058 | 11 associated lipids |
Airway Remodeling | D056151 | 3 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jiang XW et al. | Effects of low-dose Beraprost sodium, a stable prostaglandin I2 analogue, on reperfusion injury to rabbit lungs. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9817723 |
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Hellyer PW et al. | The effects of hyperoxia on the biosynthesis of cyclooxygenase products and haemodynamic response to nitric oxide synthase inhibition with L-NAME in endotoxaemic pigs. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9811434 |
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Obase Y et al. | Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma. | 1998 | Chest | pmid:9792572 |
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Smith CJ et al. | Pharmacological analysis of cyclooxygenase-1 in inflammation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9789085 |
Thomson M et al. | Prostanoid synthesis in whole blood cells from fish of the Arabian Gulf. | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9787758 |
John H et al. | Development and review of radioimmunoassay of 12-S-hydroxyheptadecatrienoic acid. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9785378 |
Lindström T et al. | The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. | 1998 | J Trauma | pmid:9783614 |
Chen MF et al. | Vitamin E supplementation attenuates myointimal proliferation of the abdominal aorta after balloon injury in diet-induced hypercholesterolemic rabbits. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9777654 |
Chavali SR et al. | Increased production of TNF-alpha and decreased levels of dienoic eicosanoids, IL-6 and IL-10 in mice fed menhaden oil and juniper oil diets in response to an intraperitoneal lethal dose of LPS. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774171 |
Power I et al. | Effects of ketorolac and dextran-70 alone and in combination on haemostasis. | 1998 | Acta Anaesthesiol Scand | pmid:9773144 |
Brinkmann A et al. | Vasopressor hormone response following mesenteric traction during major abdominal surgery. | 1998 | Acta Anaesthesiol Scand | pmid:9773140 |
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van Dijk AP et al. | Transdermal nicotine inhibits interleukin 2 synthesis by mononuclear cells derived from healthy volunteers. | 1998 | Eur. J. Clin. Invest. | pmid:9767362 |
Oosaki R et al. | Correlation among urinary eosinophil protein X, leukotriene E4, and 11-dehydrothromboxane B2 in patients with spontaneous asthmatic attack. | 1998 | Clin. Exp. Allergy | pmid:9761018 |
Gajdos M et al. | Effective long-term inhibition of thromboxane production but not of serotonin release in patients with coronary heart disease by 30 mg/d acetylsalicylic acid dosage. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758203 |
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Gonchar MV et al. | Lack of direct connection between arachidonic acid release and prostanoid synthesis upon differentiation of U937 cell. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9731221 |
Roberts LJ et al. | Metabolism of thromboxane B2 in the monkey. | 1978 | J. Biol. Chem. | pmid:97291 |
Jain SK et al. | Relationship of blood thromboxane-B2 (TxB2) with lipid peroxides and effect of vitamin E and placebo supplementation on TxB2 and lipid peroxide levels in type 1 diabetic patients. | 1998 | Diabetes Care | pmid:9727900 |
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Fagugli RM et al. | Reduction of renal functional reserve in kidney transplant recipients: a possible role of arachidonic acid metabolism alterations. | 1998 | Clin. Nephrol. | pmid:9696430 |
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Lebel B et al. | Inhibition of mediator release from dispersed nasal polyp cells by cyclosporin A. | 1998 | Int. Arch. Allergy Immunol. | pmid:9693278 |
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Tewes KS et al. | Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification. | 1998 | Anal. Biochem. | pmid:9683522 |
De La Cruz JP et al. | Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. | 1998 | Eur. J. Pharmacol. | pmid:9683018 |
Onizuka M et al. | Suppression of prostanoid formation and regulation of peripheral circulation after surgery using thrombin inhibitor (MD805). | 1998 | Surg. Today | pmid:9681611 |
Cheng Z et al. | Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. | 1998 | Inflammation | pmid:9675607 |
Miyamoto A et al. | The role of thromboxane A2 in regulating porcine basilar arterial tone. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9673964 |
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Kunitoh H et al. | A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients. | 1998 | J Asthma | pmid:9669829 |
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Nagao T et al. | Effect of lipo-prostaglandin E1 on crescentic-type anti-glomerular basement membrane nephritis in rats. | 1998 | Eur. J. Pharmacol. | pmid:9650829 |
Assaley J et al. | Effects of magnesium sulfate infusion upon clotting parameters in patients with pre-eclampsia. | 1998 | J Perinat Med | pmid:9650132 |
Mainwaring RD et al. | Complement activation and cytokine generation after modified Fontan procedure. | 1998 | Ann. Thorac. Surg. | pmid:9647087 |
Whiteford M et al. | Effect of liposome-encapsulated hemoglobin on the development of endotoxin-induced shock in the rat. | 1998 | Shock | pmid:9645495 |
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Bereczki C et al. | Increased platelet thromboxane release in focal segmental glomerulosclerosis. | 1998 | Nephrol. Dial. Transplant. | pmid:9641208 |
Tu Y et al. | Effect of intra-arachnoid space perfusion on thromboxane A and prostacycline in experimental spinal cord injury. | 1997 | J. Tongji Med. Univ. | pmid:9639784 |
Lees P et al. | Pharmacodynamics and pharmacokinetics of tolfenamic acid in ruminating calves: evaluation in models of acute inflammation. | 1998 | Vet. J. | pmid:9638074 |
Cadroy Y et al. | Arachidonic acid enhances the tissue factor expression of mononuclear cells by the cyclo-oxygenase-1 pathway: beneficial effect of n-3 fatty acids. | 1998 | J. Immunol. | pmid:9637532 |
Franconi F et al. | Further insights into the anti-aggregating activity of NMDA in human platelets. | 1998 | Br. J. Pharmacol. | pmid:9630340 |
Ozyazgan I et al. | Eicosanoids and inflammatory cells in frostbitten tissue: prostacyclin, thromboxane, polymorphonuclear leukocytes, and mast cells. | 1998 | Plast. Reconstr. Surg. | pmid:9623831 |
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Bassiouny HS et al. | Low flow enhances platelet activation after acute experimental arterial injury. | 1998 | J. Vasc. Surg. | pmid:9620144 |