MeSH term | MeSH ID | Detail |
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Adenocarcinoma | D000230 | 166 associated lipids |
Acidosis | D000138 | 13 associated lipids |
Abortion, Habitual | D000026 | 5 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Schelzig H et al. | Role of recombinant hirudin in a pig-to-human lung transplantation model. | 2002 | Transplant. Proc. | pmid:12270449 |
Huang CG et al. | Effect of berberine on arachidonic acid metabolism in rabbit platelets and endothelial cells. | 2002 | Thromb. Res. | pmid:12297129 |
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Sheu JR et al. | Mechanisms involved in the antiplatelet activity of magnesium in human platelets. | 2002 | Br. J. Haematol. | pmid:12472585 |
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Bruno A et al. | Aspirin and urinary 11-dehydrothromboxane B(2) in African American stroke patients. | 2002 | Stroke | pmid:11779889 |
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Saareks V et al. | Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. | 2002 | Pharmacol. Toxicol. | pmid:12403056 |
Obase Y et al. | Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. | 2002 | Chest | pmid:11796443 |
Kirchheiner J et al. | Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. | 2002 | Clin. Pharmacol. Ther. | pmid:12152005 |
Wang L et al. | Enhancement of human platelet activation by the combination of low concentrations of collagen and rabbit anticardiolipin antibodies. | 2002 | Br. J. Haematol. | pmid:12199800 |
Park CH et al. | Investigations of new lead structures for the design of novel cyclooxygenase-2 inhibitors. | 2002 | Eur J Med Chem | pmid:12204472 |
Cipollone F et al. | Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy. | 2002 | Circulation | pmid:12135935 |
Association between ibuprofen, aspirin therapy found. | 2002 | J Am Dent Assoc | pmid:12136787 | |
Rinder HM et al. | Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. | 2002 | J Clin Pharmacol | pmid:12162470 |
Wong DA et al. | Discrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2). | 2002 | J. Exp. Med. | pmid:12163563 |
Kiemer AK et al. | Inhibition of cyclooxygenase-2 by natriuretic peptides. | 2002 | Endocrinology | pmid:11861506 |
Huang K et al. | Role of selenium in cytoprotection against cholesterol oxide-induced vascular damage in rats. | 2002 | Atherosclerosis | pmid:11947907 |
Hu X et al. | [The influence of nasal continual positive airway pressure on some vasoactive substances in patients with obstructive sleep apnea syndrome]. | 2002 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11953098 |
Burleigh ME et al. | Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. | 2002 | Circulation | pmid:11956125 |
Jankov RP et al. | Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism. | 2002 | Am. J. Respir. Crit. Care Med. | pmid:12119234 |
Giardiello FM et al. | Primary chemoprevention of familial adenomatous polyposis with sulindac. | 2002 | N. Engl. J. Med. | pmid:11932472 |
Signorello MG et al. | Effect of homocysteine on arachidonic acid release in human platelets. | 2002 | Eur. J. Clin. Invest. | pmid:11952814 |
Appleyard CB et al. | Temporal changes in colonic vascular architecture and inflammatory mediator levels in animal models of colitis. | 2002 | Dig. Dis. Sci. | pmid:12353846 |
Saldeen P et al. | Structural, functional and circulatory placental changes associated with impaired glucose metabolism. | 2002 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:12381475 |
Zhang H et al. | [Perioperative lung injury in ventricular septal defect with severe pulmonary hypertension, a clinical study of 31 cases]. | 2002 | Zhonghua Yi Xue Za Zhi | pmid:12425808 |
Jones CJ et al. | In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs. | 2002 | Am. J. Vet. Res. | pmid:12428662 |
Buluç M et al. | Effect of misoprostol and indomethacin on cyclooxygenase induction and eicosanoid production in carrageenan-induced air pouch inflammation in rats. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:12428691 |
Gray PA et al. | Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. | 2002 | Br. J. Pharmacol. | pmid:12429575 |
Valeri CR et al. | Circulation and hemostatic function of autologous fresh, liquid-preserved, and cryopreserved baboon platelets transfused to correct an aspirin-induced thrombocytopathy. | 2002 | Transfusion | pmid:12430680 |
Wilner KD et al. | Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:12211219 |
Molina V et al. | D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12213431 |
Koizumi T et al. | Inhibition of endogenous nitric oxide during endotoxemia in awake sheep - effects of Nomega-nitro-l-arginine on the distribution of pulmonary vascular resistance and prostanoid products. | 2002 | Exp. Lung Res. | pmid:12217213 |
Khan I et al. | Altered expression of Na(+)/H(+) exchanger isoforms 1 and 3 in clipped and unclipped kidneys of a 2-kidney-1-clip Goldblatt model of hypertension. | 2002 | Nephron | pmid:12218313 |
Yokoyama C et al. | Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. | 2002 | Circulation | pmid:12403673 |
Evgenov OV et al. | Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep. | 2002 | Eur. Respir. J. | pmid:12412689 |
Ferlito M et al. | Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production. | 2002 | J. Endotoxin Res. | pmid:12701623 |