MeSH term | MeSH ID | Detail |
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Adenocarcinoma | D000230 | 166 associated lipids |
Acidosis | D000138 | 13 associated lipids |
Abortion, Habitual | D000026 | 5 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bockman RS | Prostaglandin production by human blood monocytes and mouse peritoneal macrophages: synthesis dependent on in vitro culture conditions. | 1981 | Prostaglandins | pmid:6782622 |
Rittenhouse-Simmons S | Differential activation of platelet phospholipases by thrombin and ionophore A23187. | 1981 | J. Biol. Chem. | pmid:6783655 |
Galli C et al. | Differential effects of dietary fatty acids on the accumulation of arachidonic acid and its metabolic conversion through the cyclooxygenase and lipoxygenase in platelets and vascular tissue. | 1981 | Lipids | pmid:6783805 |
Rao GH et al. | Effect of Amrinone, a cardiotonic drug, on hemodynamics and platelet function. | 1981 | Prostaglandins Med | pmid:6784136 |
Strand JC et al. | Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. | 1981 | Am. J. Physiol. | pmid:6787931 |
Stuart MJ et al. | Abnormal platelet function and arachidonate metabolism in chronic idiopathic thrombocytopenic purpura. | 1981 | Blood | pmid:6788109 |
Shaw JO et al. | Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor). | 1981 | Biochim. Biophys. Acta | pmid:7213765 |
Kass MA et al. | Prostaglandin and thromboxane synthesis by microsomes of inflamed rabbit ciliary body--iris. | 1981 | Invest. Ophthalmol. Vis. Sci. | pmid:7216665 |
Sakio H et al. | [Release of thromboxane A2 during hemorrhagic shock (author's transl)]. | 1981 | Masui | pmid:7218508 |
Kawaguchi H et al. | Thromboxane B2 biosynthesis and phospholipids hydrolysis in platelets from hypercholesterolemic rabbits. | 1981 | Lipids | pmid:7219079 |
Handin RI and Alexander RW | Humoral heartache -- do platelets have a role? | 1981 | N. Engl. J. Med. | pmid:7010170 |
Robertson RM et al. | Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. | 1981 | N. Engl. J. Med. | pmid:7010173 |
Hladovec J | Prostaglandins and endothelial stability. | 1981 | Arzneimittelforschung | pmid:7011332 |
Sananès N et al. | A role for prostaglandins in decidualization of the rat uterus. | 1981 | J. Endocrinol. | pmid:7012263 |
Kadowitz PJ et al. | Pulmonary vascular responses to prostaglandins. | 1981 | Fed. Proc. | pmid:7014258 |
Coker SJ et al. | Aspirin inhibits the early myocardial release of thromboxane B2 and ventricular ectopic activity following acute coronary artery occlusion in dogs. | 1981 | Br. J. Pharmacol. | pmid:7284679 |
Fasce L et al. | [Effects of glucocorticoids on the gastrointestinal tract of normal rats and rats deficient in endogenous prostaglandins]. | 1981 | Boll. Soc. Ital. Biol. Sper. | pmid:7295403 |
Tada M et al. | Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris. | 1981 | Circulation | pmid:7296786 |
McManus LM et al. | Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon. | 1981 | Lab. Invest. | pmid:7300244 |
Uyama O et al. | Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular disease. | 1981 | Prostaglandins Med | pmid:7302001 |
Smith JB and Jubiz W | OKY-1581: a selective inhibitor of thromboxane synthesis in vivo and in vitro. | 1981 | Prostaglandins | pmid:7302264 |
Rifkin BR and Tai HH | Elevated thromboxane B2 levels in periodontal disease. | 1981 | J. Periodont. Res. | pmid:6453981 |
Mehta J and Mehta P | Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed. | 1981 | Acta Med. Scand. Suppl. | pmid:6948499 |
Rubenstein MD et al. | Platelet activation in clinical coronary artery disease and spasm. | 1981 | Am. Heart J. | pmid:6455912 |
Walker ID et al. | A double blind study of prostacyclin in cardiopulmonary bypass surgery. | 1981 | Br. J. Haematol. | pmid:6457624 |
Bray MA et al. | Prostaglandin generation by separated human blood mononuclear cell fractions. | 1981 | Int. J. Immunopharmacol. | pmid:6949878 |
Capitanio A et al. | Platelet abnormalities in renal transplantation. | 1981 | Proc Eur Dial Transplant Assoc | pmid:6460244 |
Bombardieri S et al. | The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs. | 1981 | Br. J. Pharmacol. | pmid:6895043 |
Harms BA et al. | Prostaglandin release and altered microvascular integrity after burn injury. | 1981 | J. Surg. Res. | pmid:6895238 |
Ylikorkala O et al. | Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies. | 1981 | Am. J. Obstet. Gynecol. | pmid:6895277 |
Ishihara Y et al. | [Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)]. | 1981 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:6895531 |
Kinney EL and Demers LM | Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon. | 1981 | Prostaglandins Med | pmid:6895673 |
Barnett AH et al. | Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes. | 1981 | Clin. Endocrinol. (Oxf) | pmid:6895721 |
Greenwald JE et al. | Argentation thin layer chromatography of arachidonic acid metabolites isolated from human platelets. | 1981 | Prostaglandins | pmid:7208953 |
Terragno A et al. | High performance liquid chromatography and UV detection for the separation and quantitation of prostaglandins. | 1981 | Prostaglandins | pmid:6894197 |
Beck N and Shaw JO | Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. | 1981 | Am. J. Physiol. | pmid:7468800 |
Halushka PV et al. | Increased platelet arachidonic acid metabolism in diabetes mellitus. | 1981 | Diabetes | pmid:6795072 |
Taylor L et al. | Prostaglandin production and cellular aging. | 1981 | Mech. Ageing Dev. | pmid:6946268 |
Young MK et al. | Aging: effects on the prostaglandin production by skeletal muscle of male rhesus monkeys (Macaca mulatta). | 1981 | Mech. Ageing Dev. | pmid:6946269 |
Hwang DH et al. | In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets. | 1981 | Lipids | pmid:6792442 |
Tulenko TN | The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. | 1981 | Prostaglandins | pmid:6794096 |
Williamson EM et al. | Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester. | 1981 | Biochem. Pharmacol. | pmid:6794576 |
Ylikorkala O et al. | Prostacyclin and thromboxane in diabetes. | 1981 | Br Med J (Clin Res Ed) | pmid:6794795 |
Lee SH et al. | Prostacyclin and thromboxane A2 in thrombotic thrombocytopenic purpura. | 1981 | Br Med J (Clin Res Ed) | pmid:6797537 |
Agradi E et al. | Dietary linoleic acid, accumulation of arachidonic acid in tissue lipids and production of TXB2 and PGI2 in the cardiovascular system. | 1981 | Prog. Lipid Res. | pmid:7043483 |
Feuerstein N and Ramwell PW | OKY-1581, a potential selective thromboxane synthetase inhibitor. | 1981 | Eur. J. Pharmacol. | pmid:7195815 |
Satoh H et al. | Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. | 1981 | Prostaglandins | pmid:7197382 |
Steinhauer HB and Hertting G | Lowering of the convulsive threshold by non-steroidal anti-inflammatory drugs. | 1981 | Eur. J. Pharmacol. | pmid:7202518 |
Robson MC and Heggers JP | Evaluation of hand frostbite blister fluid as a clue to pathogenesis. | 1981 | J Hand Surg Am | pmid:7204918 |
Subbiah MT et al. | Effect of specific estrogens on prostaglandin synthesis in aorta and thrombocytes of female pigeons. | 1981 | Proc. Soc. Exp. Biol. Med. | pmid:7208490 |