MeSH term | MeSH ID | Detail |
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Adenocarcinoma | D000230 | 166 associated lipids |
Acidosis | D000138 | 13 associated lipids |
Abortion, Habitual | D000026 | 5 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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di Minno G et al. | Effects of any epoxymethano stable analogue of prostaglandin endoperoxides (U-46619) on human platelets. | 1981 | Thromb. Haemost. | pmid:6266066 |
Handler JS | Vasopressin-prostaglandin interactions in the regulation of epithelial cell permeability to water. | 1981 | Kidney Int. | pmid:6267350 |
Best LC et al. | Strontium ions induce production of thromboxane B2 and secretion of 5-hydroxytryptamine in washed human platelets. | 1981 | Biochem. Pharmacol. | pmid:6268118 |
Nordøy A | Lipids and thrombogenesis. | 1981 | Ann. Clin. Res. | pmid:7018362 |
Moncada S and Vane JR | Prostacyclin and blood coagulation. | 1981 | Drugs | pmid:7018874 |
Ylikorkala O et al. | Increased prostacyclin and thromboxane production in man during cardiopulmonary bypass. | 1981 | J. Thorac. Cardiovasc. Surg. | pmid:7019583 |
Hales CA et al. | Role of thromboxane and prostacyclin in pulmonary vasomotor changes after endotoxin in dogs. | 1981 | J. Clin. Invest. | pmid:7021593 |
Hyman AL et al. | Prostaglandins and the lung. | 1981 | Med. Clin. North Am. | pmid:7024664 |
Baroody RA and Bito LZ | The impermeability of the basic cell membrane to thromboxane-B2' prostacyclin and 6-keto-PGF 1 alpha. | 1981 | Prostaglandins | pmid:7010455 |
Rosenfeld J et al. | Extractive alkylation of prostaglandins. | 1981 | Prostaglandins | pmid:7010456 |
Ylikorkala O et al. | Effect of cytostatics on prostaglandin F2 alpha prostacyclin, and thromboxane in patients with gynecologic malignancies. | 1981 | Obstet Gynecol | pmid:7024882 |
Tanaka M et al. | Increased prostacyclin synthesizing activity in human ripening uterine cervix. | 1981 | Prostaglandins | pmid:7010458 |
Siess W et al. | Stimulated platelet aggregation, thromboxane B2 formation and platelet sensitivity to prostacyclin - a critical evaluation. | 1981 | Thromb. Haemost. | pmid:7025338 |
Gonzalez-Crussi F et al. | Prostaglandins in histiocytosis-X. PG synthesis by histiocytosis-X cells. | 1981 | Am. J. Clin. Pathol. | pmid:6970520 |
Webb PJ et al. | Do prostacyclin and thromboxane play a role in endotoxic shock? | 1981 | Br J Surg | pmid:7025959 |
Araki H et al. | Mechanism of protection against arachidonate induced sudden death by glucocorticoid. | 1981 | Prostaglandins | pmid:7232764 |
Parks WM et al. | Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis. | 1981 | J. Pharmacol. Exp. Ther. | pmid:7026767 |
Roselló J et al. | Quantitative profiling of the metabolic cascade of arachidonic acid by capillary gas chromatography mass spectrometry. | 1981 | Biomed. Mass Spectrom. | pmid:7236862 |
Cook JA et al. | Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2. | 1981 | Circ. Shock | pmid:7237685 |
Chong BH et al. | Heparin-induced thrombocytopenia: effect of heparin platelet antibody on platelets. | 1981 | Br. J. Haematol. | pmid:7317283 |
Gordon D et al. | Selective inhibition of thromboxane biosynthesis in human blood mononuclear cells and the effects of mitogen-stimulated lymphocyte proliferation. | 1981 | Br. J. Pharmacol. | pmid:7317694 |
Satoh K et al. | Augmented malondialdehyde production by platelets from patients with cerebrovascular disorders. | 1981 | Jpn. Circ. J. | pmid:7321143 |
Matsumoto M et al. | Platelet aggregation induced by arachidonic acid and thromboxane generation in patients with hypertension or cerebrovascular disease. | 1981 | Prostaglandins Med | pmid:7323212 |
Smith MC and Dunn MJ | Impaired platelet thromboxane production in renal failure. | 1981 | Nephron | pmid:7329487 |
Lagarde M et al. | Inhibition of thrombin-induced platelet arachidonic acid release by 15-hydroperoxy-arachidonic acid. | 1981 | Biochem. Biophys. Res. Commun. | pmid:7259783 |
Livio M et al. | Differential effects of itanoxone--a new hypolipidemic and hypouricemic drug--on platelet and vascular prostaglandin generation in rats. | 1981 | Atherosclerosis | pmid:7259827 |
Sterin-Borda L et al. | Stimulating effect of thromboxane B2 on isolated rat atria. | 1981 | Experientia | pmid:7262286 |
Roberts LJ et al. | Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites. | 1981 | J. Biol. Chem. | pmid:7263660 |
Zijlstra FJ and Vincent JE | Contractile characteristics of the rat stomach strip and the rabbit aorta and mesenteric artery. | 1981 | J Pharmacol Methods | pmid:7265989 |
Gilani SH and Persaud TV | Embryopathic effects of thromboxane B2 in the chick. | 1981 | Prostaglandins Med | pmid:7267828 |
Anderson CB et al. | Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. | 1981 | Transplant. Proc. | pmid:7268892 |
Hirsh PD et al. | Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. | 1981 | N. Engl. J. Med. | pmid:6894016 |
Allan G and Levi R | Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro. | 1981 | J. Pharmacol. Exp. Ther. | pmid:6894166 |
Malemud CJ et al. | Prostaglandin biosynthesis by lapine articular chondrocytes in culture. | 1981 | Biochim. Biophys. Acta | pmid:6894251 |
Ohnishi H et al. | Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2. | 1981 | Prostaglandins Med | pmid:6894333 |
Coker SJ et al. | Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias. | 1981 | Nature | pmid:6894485 |
Sobel M et al. | Circulating platelet products in unstable angina pectoris. | 1981 | Circulation | pmid:6450001 |
Seitz M et al. | The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes. | 1981 | Agents Actions | pmid:7340450 |
Catalano PM et al. | Platelet recovery from aspirin inhibition in vivo; differing patterns under various assay conditions. | 1981 | Blood | pmid:7448419 |
Halushka PV et al. | Increased platelet arachidonic acid metabolism in diabetes mellitus. | 1981 | Diabetes | pmid:6795072 |
Taylor L et al. | Prostaglandin production and cellular aging. | 1981 | Mech. Ageing Dev. | pmid:6946268 |
Young MK et al. | Aging: effects on the prostaglandin production by skeletal muscle of male rhesus monkeys (Macaca mulatta). | 1981 | Mech. Ageing Dev. | pmid:6946269 |
Honn KV and Meyer J | Thromboxanes and prostacyclin: positive and negative modulators of tumor growth. | 1981 | Biochem. Biophys. Res. Commun. | pmid:6274330 |
Corby DG and O'Barr TP | Neonatal platelet function: a membrane-related phenomenon? | 1981 | Haemostasis | pmid:7250785 |
Wonders TR et al. | Reduced plasma thromboxane elevation during partial cardiopulmonary bypass in thrombocytopenic sheep. | 1981 | Trans Am Soc Artif Intern Organs | pmid:7331082 |
Mezzano D et al. | Evidence that platelet buoyant density, but not size, correlates with platelet age in man. | 1981 | Am. J. Hematol. | pmid:7270546 |
Brox JH et al. | The effect of cod liver oil and corn oil on platelets and vessel wall in man. | 1981 | Thromb. Haemost. | pmid:7031981 |
Hirsh PD et al. | Prostaglandins and ischemic heart disease. | 1981 | Am. J. Med. | pmid:7032286 |
Dunham BM et al. | Role of prostaglandins in positive end-expiratory pressure-induced negative inotropism. | 1981 | Am. J. Physiol. | pmid:7034549 |
Strano A et al. | Thromboxane formation by platelets and platelet sensitivity to prostacyclin in patients with acute myocardial infarction. | 1981 | Thromb. Haemost. | pmid:7036402 |