MeSH term | MeSH ID | Detail |
---|---|---|
Cholecystitis, Acute | D041881 | 1 associated lipids |
Gastric Dilatation | D013271 | 1 associated lipids |
Stomach Volvulus | D013277 | 1 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Singh D et al. | Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets. | 1981 | Am. J. Hematol. | pmid:6274189 |
Rao GH et al. | Effect of Amrinone, a cardiotonic drug, on hemodynamics and platelet function. | 1981 | Prostaglandins Med | pmid:6784136 |
Strand JC et al. | Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. | 1981 | Am. J. Physiol. | pmid:6787931 |
Stuart MJ et al. | Abnormal platelet function and arachidonate metabolism in chronic idiopathic thrombocytopenic purpura. | 1981 | Blood | pmid:6788109 |
Handin RI and Alexander RW | Humoral heartache -- do platelets have a role? | 1981 | N. Engl. J. Med. | pmid:7010170 |
Robertson RM et al. | Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. | 1981 | N. Engl. J. Med. | pmid:7010173 |
Hladovec J | Prostaglandins and endothelial stability. | 1981 | Arzneimittelforschung | pmid:7011332 |
Sananès N et al. | A role for prostaglandins in decidualization of the rat uterus. | 1981 | J. Endocrinol. | pmid:7012263 |
Kadowitz PJ et al. | Pulmonary vascular responses to prostaglandins. | 1981 | Fed. Proc. | pmid:7014258 |
Ingerman-Wojenski C et al. | Bovine endothelial cells in culture produce thromboxane as well as prostacyclin. | 1981 | J. Clin. Invest. | pmid:7014633 |
Takasu N et al. | Augmentation of prostacyclin and depression of PGE2, PGF2 alpha and thromboxane A2 by TSH in cultured porcine thyroid cells: an important role of prostacyclin in maintaining thyroid cell function. | 1981 | FEBS Lett. | pmid:7016591 |
Utsunomiya T et al. | Treatment of pulmonary embolism with positive end-expiratory pressure and prostaglandin E1. | 1981 | Surg Gynecol Obstet | pmid:7017981 |
Dembélé-Duchesne MJ et al. | Some new prospects in the mechanism of control of arachidonate metabolism in human placenta and amnion. | 1981 | Prostaglandins | pmid:6801732 |
Fasce L et al. | [Effects of glucocorticoids on the gastrointestinal tract of normal rats and rats deficient in endogenous prostaglandins]. | 1981 | Boll. Soc. Ital. Biol. Sper. | pmid:7295403 |
Tada M et al. | Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris. | 1981 | Circulation | pmid:7296786 |
McManus LM et al. | Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon. | 1981 | Lab. Invest. | pmid:7300244 |
Uyama O et al. | Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular disease. | 1981 | Prostaglandins Med | pmid:7302001 |
Smith JB and Jubiz W | OKY-1581: a selective inhibitor of thromboxane synthesis in vivo and in vitro. | 1981 | Prostaglandins | pmid:7302264 |
Spector SL et al. | Clinical response and serum prostaglandin levels in aspirin idiosyncrasy. Effect of aspirin and a new nonsteroidal anti-inflammatory agent. | 1981 | Chest | pmid:7307588 |
Meyers KM et al. | Evaluation of the platelet storage pool deficiency in the feline counterpart of the Chediak-Higashi syndrome. | 1981 | Am. J. Hematol. | pmid:7315839 |
Rifkin BR and Tai HH | Elevated thromboxane B2 levels in periodontal disease. | 1981 | J. Periodont. Res. | pmid:6453981 |
Mehta J and Mehta P | Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed. | 1981 | Acta Med. Scand. Suppl. | pmid:6948499 |
Chong BH et al. | Heparin-induced thrombocytopenia: effect of heparin platelet antibody on platelets. | 1981 | Br. J. Haematol. | pmid:7317283 |
Rubenstein MD et al. | Platelet activation in clinical coronary artery disease and spasm. | 1981 | Am. Heart J. | pmid:6455912 |
Gordon D et al. | Selective inhibition of thromboxane biosynthesis in human blood mononuclear cells and the effects of mitogen-stimulated lymphocyte proliferation. | 1981 | Br. J. Pharmacol. | pmid:7317694 |
Walker ID et al. | A double blind study of prostacyclin in cardiopulmonary bypass surgery. | 1981 | Br. J. Haematol. | pmid:6457624 |
Bray MA et al. | Prostaglandin generation by separated human blood mononuclear cell fractions. | 1981 | Int. J. Immunopharmacol. | pmid:6949878 |
Capitanio A et al. | Platelet abnormalities in renal transplantation. | 1981 | Proc Eur Dial Transplant Assoc | pmid:6460244 |
Kinney EL and Demers LM | Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon. | 1981 | Prostaglandins Med | pmid:6895673 |
Barnett AH et al. | Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes. | 1981 | Clin. Endocrinol. (Oxf) | pmid:6895721 |
Catalano PM et al. | Platelet recovery from aspirin inhibition in vivo; differing patterns under various assay conditions. | 1981 | Blood | pmid:7448419 |
Grimm LJ et al. | Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation. | 1981 | Thromb. Res. | pmid:6801806 |
Taylor L et al. | Prostaglandin production and cellular aging. | 1981 | Mech. Ageing Dev. | pmid:6946268 |
Worthington RE and Nakeff A | Thromboxane synthesis in megakaryocytes isolated by centrifugal elutriation. | 1981 | Blood | pmid:6786393 |
Corby DG and O'Barr TP | Neonatal platelet function: a membrane-related phenomenon? | 1981 | Haemostasis | pmid:7250785 |
Hwang DH et al. | In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets. | 1981 | Lipids | pmid:6792442 |
Tulenko TN | The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. | 1981 | Prostaglandins | pmid:6794096 |
Williamson EM et al. | Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester. | 1981 | Biochem. Pharmacol. | pmid:6794576 |
Ylikorkala O et al. | Prostacyclin and thromboxane in diabetes. | 1981 | Br Med J (Clin Res Ed) | pmid:6794795 |
Lee SH et al. | Prostacyclin and thromboxane A2 in thrombotic thrombocytopenic purpura. | 1981 | Br Med J (Clin Res Ed) | pmid:6797537 |
Igarashi K et al. | Effect of polyamines on prostaglandin synthesis in various cell-free systems. | 1981 | Biochem. Biophys. Res. Commun. | pmid:6800368 |
Morris HG et al. | Variables associated with radioimmunoassay of prostaglandins in plasma. | 1981 | Prostaglandins | pmid:6803306 |
Landgraf-Leurs MM et al. | Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats. | 1981 | Prostaglandins | pmid:6798637 |
Feuerstein N and Ramwell PW | OKY-1581, a potential selective thromboxane synthetase inhibitor. | 1981 | Eur. J. Pharmacol. | pmid:7195815 |
Satoh H et al. | Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. | 1981 | Prostaglandins | pmid:7197382 |
Steinhauer HB and Hertting G | Lowering of the convulsive threshold by non-steroidal anti-inflammatory drugs. | 1981 | Eur. J. Pharmacol. | pmid:7202518 |
Robson MC and Heggers JP | Evaluation of hand frostbite blister fluid as a clue to pathogenesis. | 1981 | J Hand Surg Am | pmid:7204918 |
Subbiah MT et al. | Effect of specific estrogens on prostaglandin synthesis in aorta and thrombocytes of female pigeons. | 1981 | Proc. Soc. Exp. Biol. Med. | pmid:7208490 |
Brox JH et al. | The effect of cod liver oil and corn oil on platelets and vessel wall in man. | 1981 | Thromb. Haemost. | pmid:7031981 |
Hirsh PD et al. | Prostaglandins and ischemic heart disease. | 1981 | Am. J. Med. | pmid:7032286 |