MeSH term | MeSH ID | Detail |
---|---|---|
Cholecystitis, Acute | D041881 | 1 associated lipids |
Gastric Dilatation | D013271 | 1 associated lipids |
Stomach Volvulus | D013277 | 1 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Papanicolaou N et al. | Selective inhibition of renal thromboxane biosynthesis increased sodium excretion rate in normal and saline-loaded rats. | 1985 | Clin. Sci. | pmid:3880524 |
Bakhle YS et al. | Differential release of eicosanoids by bradykinin, arachidonic acid and calcium ionophore A23187 in guinea-pig isolated perfused lung. | 1985 | Br. J. Pharmacol. | pmid:2996675 |
Bakhle YS and Grantham CJ | Selective effect of pulmonary oedema on prostaglandin E2 pharmacokinetics in rat lung. | 1985 | Biochem. Pharmacol. | pmid:3935117 |
Brown EM and Swartz SL | Production of prostaglandins by dispersed cells and fragments from bovine parathyroid glands. | 1985 | Prostaglandins | pmid:3883430 |
Ding YA et al. | Angiotensin II effects on platelet function. | 1985 | J Hypertens Suppl | pmid:2856711 |
Hugli TE and Marceau F | Effects of the C5a anaphylatoxin and its relationship to cyclo-oxygenase metabolites in rabbit vascular strips. | 1985 | Br. J. Pharmacol. | pmid:3921089 |
Boraschi D et al. | Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons. | 1985 | J. Immunol. | pmid:3923110 |
Ment LR et al. | Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants. | 1985 | J. Pediatr. | pmid:3906073 |
Slotman GJ et al. | Thromboxane, prostacyclin, and the hemodynamic effects of graded bacteremic shock. | 1985 | Circ. Shock | pmid:3915237 |
De Caterina R et al. | Nitrates and endothelial prostacyclin production: studies in vitro. | 1985 | Circulation | pmid:3917245 |
Walenga RW et al. | Megakaryocyte thromboxane production induced by platelet stimuli during in vitro culture. | 1985 | Exp. Hematol. | pmid:3918879 |
Walsh SW | Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. | 1985 | Am. J. Obstet. Gynecol. | pmid:3923838 |
Nitz RE and Martorana PA | The activity of molsidomine in experimental models of ischemic cardiac disease. | 1985 | Am. Heart J. | pmid:3919549 |
Bowers GJ et al. | Prostanoid production by lipopolysaccharide-stimulated Kupffer cells. | 1985 | J. Surg. Res. | pmid:3887037 |
Kiyomiya K and Oh-ishi S | Involvement of arachidonic acid metabolites in acute inflammation: detection of 6-keto-PGF1 alpha, thromboxane B2 and PGD2 in rat pleurisy induced by phorbol myristate acetate. | 1985 | Jpn. J. Pharmacol. | pmid:3936958 |
Bottoms GD et al. | Endotoxin-induced eicosanoid production by equine vascular endothelial cells and neutrophils. | 1985 | Circ. Shock | pmid:3919961 |
Stenmark KR et al. | Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. | 1985 | Am. J. Physiol. | pmid:3923843 |
McKechnie K et al. | Metabolic and cardiovascular effects of endotoxin infusion in conscious unrestrained rats: effects of methylprednisolone and BW755C. | 1985 | Circ. Shock | pmid:3919962 |
Panse M et al. | An improved malondialdehyde assay for estimation of thromboxane synthase activity in washed human blood platelets. | 1985 | Prostaglandins | pmid:3937179 |
Toivanen J et al. | Differential inhibition of platelet thromboxane and lung prostacyclin production by sulphinpyrazone, acetylsalicylic acid and indomethacin by human tissues in vitro. | 1985 | Thromb. Res. | pmid:3920778 |
Yamaguchi M and Mori N | 6-Keto prostaglandin F1 alpha, thromboxane B2, and 13,14-dihydro-15-keto prostaglandin F concentrations of normotensive and preeclamptic patients during pregnancy, delivery, and the postpartum period. | 1985 | Am. J. Obstet. Gynecol. | pmid:3838119 |
Patrono C et al. | Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus. | 1985 | J. Clin. Invest. | pmid:3900132 |
O'Keefe EH et al. | Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro. | 1985 | Prostaglandins | pmid:3925501 |
Schmitz JM et al. | Vascular prostaglandin and thromboxane production in a canine model of myocardial ischemia. | 1985 | Circ. Res. | pmid:3926340 |
Numano F et al. | Prostacyclin and variant angina. | 1985 | Ann. N. Y. Acad. Sci. | pmid:3865605 |
Strano A et al. | [Formation of platelet thromboxane in a patient with type I glycogenosis]. | 1985 | Recenti Prog Med | pmid:3868788 |
Jensen W et al. | Hemodynamic measurements in a sheep model with a hollow fiber artificial kidney containing modified cellulose. | 1985 | Life Support Syst | pmid:3870598 |
Kopp KJ et al. | Template bleeding time and thromboxane generation in the horse: effects of three non-steroidal anti-inflammatory drugs. | 1985 | Equine Vet. J. | pmid:3878280 |
Conti P et al. | Enhanced thromboxane synthesis and vacuolization in human polymorphonuclear leucocytes induced by human lymphokine containing supernatants. | 1985 | Clin. Rheumatol. | pmid:3879473 |
Mahiout A et al. | Ex vivo model for pre-clinical evaluation of dialyzers containing new membranes. | 1985 | Life Support Syst | pmid:3879954 |
Wang JP et al. | Antiplatelet effect of hsien-ho-t'sao (Agrimonia pilosa). | 1985 | Am. J. Chin. Med. | pmid:3927704 |
Gresele P et al. | Thromboxane A2 and prostacyclin do not modulate the systemic hemodynamic response to cold in humans. | 1985 | J. Lab. Clin. Med. | pmid:2932514 |
Mueller HS et al. | Systemic and transcardiac platelet activity in acute myocardial infarction in man: resistance to prostacyclin. | 1985 | Circulation | pmid:2933181 |
Shephard EG et al. | Lung function and plasma levels of thromboxane B2, 6-ketoprostaglandin F1 alpha and beta-thromboglobulin in antigen-induced asthma before and after indomethacin pretreatment. | 1985 | Br J Clin Pharmacol | pmid:2581599 |
Jouppila P et al. | Ritodrine infusion during late pregnancy: effects on fetal and placental blood flow, prostacyclin, and thromboxane. | 1985 | Am. J. Obstet. Gynecol. | pmid:3885740 |
Davì G et al. | Inhibition of platelet function by ticlopidine in arteriosclerosis obliterans of the lower limbs. | 1985 | Thromb. Res. | pmid:2933846 |
Bloom A et al. | Hemolytic-uremic syndrome: demonstration of abnormalities of platelet reactivity and insensitivity to prostaglandin I2. | 1985 | Clin. Nephrol. | pmid:3886228 |
Meyrick B et al. | Endothelial prostacyclin production is a late event in granulocyte migration into bovine pulmonary artery intimal explants. | 1985 | Blood | pmid:3904871 |
Janka HU | Platelet and endothelial function tests during metformin treatment in diabetes mellitus (short communication). | 1985 | Horm. Metab. Res. Suppl. | pmid:2934311 |
Hayashi C | [Thromboxane B2 in surgery]. | 1985 | Nihon Geka Gakkai Zasshi | pmid:2935731 |
Steinhauer HB et al. | Thromboxane B2 and beta 2-microglobulin as early indicators of renal allograft rejection. | 1985 | Proc Eur Dial Transplant Assoc Eur Ren Assoc | pmid:3887370 |
Lenhard V et al. | Transfusion-induced enhancement of prostaglandin and thromboxane release in prospective kidney graft recipients. | 1985 | Proc Eur Dial Transplant Assoc Eur Ren Assoc | pmid:3887386 |
Naesh O et al. | Platelet function in surgical stress. | 1985 | Thromb. Haemost. | pmid:2935969 |
Takahata K et al. | [Effect of PSK on prostaglandin metabolism (I)]. | 1985 | Gan To Kagaku Ryoho | pmid:3888117 |
Miyazaki H et al. | Microdetermination of prostaglandins and thromboxane B2 by gas chromatography/high-resolution selected-ion monitoring. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2936139 |
Hutchison AA et al. | Effect of endotoxemia on hypoxic pulmonary vasoconstriction in unanesthetized sheep. | 1985 | J. Appl. Physiol. | pmid:3888946 |
Kobayashi N et al. | Effect of changes in prostaglandin synthesis by platelets and vessel wall on the formation of arterial thrombosis in rabbits. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2936159 |
Ogawa K et al. | Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension. | 1985 | Klin. Wochenschr. | pmid:3889484 |
Nishikawa K et al. | (E)-7-Phenyl-7-(3-pyridyl)-6-heptenoic acid (CV-4151): a potent, specific thromboxane A2 synthetase inhibitor. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2936160 |
Vapaatalo H | Prostaglandins and coronary circulation. | 1985 | Acta Med. Scand. Suppl. | pmid:3890471 |
Takagi S and Den K | Prostacyclin and thromboxane A2 in preeclamptic umbilical circulation. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2936183 |
Ylikorkala O and Mäkilä UM | Prostacyclin and thromboxane in gynecology and obstetrics. | 1985 | Am. J. Obstet. Gynecol. | pmid:3890549 |
McGowan HM et al. | The effect of dietary alteration of prostaglandin synthesis on blood pressure and the reversal of hypertension in the one-kidney, one-clip rat. | 1985 | Prostaglandins | pmid:3859891 |
Greer IA et al. | Immunoreactive prostacyclin and thromboxane metabolites in normal pregnancy and the puerperium. | 1985 | Br J Obstet Gynaecol | pmid:3890936 |
Pedersen AK and FitzGerald GA | Cyclooxygenase inhibition, platelet function, and metabolite formation during chronic sulfinpyrazone dosing. | 1985 | Clin. Pharmacol. Ther. | pmid:3917387 |
von Schacky C et al. | Long-term effects of dietary marine omega-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans. | 1985 | J. Clin. Invest. | pmid:2997286 |
Barst RJ et al. | Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child. | 1985 | Am. Rev. Respir. Dis. | pmid:3917630 |
Stuart MJ and Dusse J | In vitro comparison of the efficacy of cyclooxygenase inhibitors on the adult versus neonatal platelet. | 1985 | Biol. Neonate | pmid:4005330 |
Amado JA et al. | Influence of acetylsalicylic acid on bleeding time and serum thromboxane B2 in diabetes mellitus type I. | 1985 | Diabete Metab | pmid:4007228 |
De Servi S et al. | [Myocardial ischemia during exertion. Correlations between blood levels of thromboxane B2 and changes in coronary flow and resistance]. | 1985 | G Ital Cardiol | pmid:4007353 |
McGinley S et al. | The effect of inhibiting brain thromboxane biosynthesis on pentylenetetrazole-induced seizure threshold. | 1985 | J. Neurosci. Res. | pmid:4009745 |
Mehta P et al. | Decreased platelet aggregation but increased thromboxane A2 generation in polycythemia vera. | 1985 | Arch. Intern. Med. | pmid:4015270 |
Kelton JG et al. | A platelet function defect in preeclampsia. | 1985 | Obstet Gynecol | pmid:3966011 |
Halenda SP et al. | Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187. | 1985 | J. Biol. Chem. | pmid:3930496 |
Mundie TG et al. | Byssinosis: Release of prostaglandins, thromboxane, and 5-hydroxytryptamine in bronchopulmonary lavage fluid after inhalation of cotton dust extracts. | 1985 | Am. J. Pathol. | pmid:3966532 |
Utsunomiya T et al. | [Circulating negative inotropic substance produced by the lung, affected by prostaglandin and thromboxane]. | 1985 | Nihon Geka Gakkai Zasshi | pmid:3160927 |
Wang CB and Chang AM | [Plasma thromboxane B2 changes in severe icteric hepatitis treated by traditional Chinese medicine--dispelling the pathogenic heat from blood, promoting blood circulation and administrating large doses of radix Paeoniae--a report of 6 cases]. | 1985 | Zhong Xi Yi Jie He Za Zhi | pmid:3161645 |
Mendieta CF et al. | Biosynthesis of prostaglandins in gingiva of patients with chronic periodontitis. | 1985 | J. Periodontol. | pmid:3919173 |
Giani E et al. | Platelets from aged rats aggregate more, but are more sensitive to prostacyclin. | 1985 | Prostaglandins Leukot Med | pmid:3003760 |
Ikkala E et al. | Haemostatic parameters in Cushing's syndrome. | 1985 | Acta Med Scand | pmid:4025006 |
Sylvester JT et al. | Prostaglandins and estradiol-induced attenuation of hypoxic pulmonary vasoconstriction. | 1985 | Chest | pmid:3840073 |
Seitz M and Hunstein W | Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosus. | 1985 | Ann. Rheum. Dis. | pmid:4026405 |
Nomura S | [Plasma levels of thromboxane B2 and 6-keto PGF1 alpha in patients with variant angina]. | 1985 | Nippon Naika Gakkai Zasshi | pmid:3840191 |
Freund HR et al. | Muscle prostaglandin production in the rat. Effect of abdominal sepsis and different amino acid formulations. | 1985 | Arch Surg | pmid:4026556 |
Haurand M and Ullrich V | Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme. | 1985 | J. Biol. Chem. | pmid:2999104 |
Prosdocimi M et al. | Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery. | 1985 | Thromb. Res. | pmid:3840290 |
Lelcuk S et al. | Thromboxane A2 moderates permeability after limb ischemia. | 1985 | Ann. Surg. | pmid:3840349 |
Morris HG et al. | Effects of salsalate (nonacetylated salicylate) and aspirin on serum prostaglandins in humans. | 1985 | Ther Drug Monit | pmid:3866409 |
Wilson L and Huang LS | Contributions of the fetoplacental unit to augmented uterine prostaglandin levels periparturition in the rat. | 1985 | Biol. Reprod. | pmid:3840391 |
Levine RF et al. | Megakaryocyte interaction with subendothelial extracellular matrix is associated with adhesion, platelet-like shape change, and thromboxane A2 production. | 1985 | Blood | pmid:4027379 |
Templeton CB et al. | Effects of repeated endotoxin injections on prostanoids, hemodynamics, endothelial cells, and survival in ponies. | 1985 | Circ. Shock | pmid:3840414 |
Roberts DG et al. | Sulindac is not renal sparing in man. | 1985 | Clin. Pharmacol. Ther. | pmid:4028619 |
Fink MP et al. | Plasma levels of 6-keto PGF1 alpha but not TxB2 increase in rats with peritonitis due to cecal ligation. | 1985 | Circ. Shock | pmid:3840415 |
Codde JP et al. | Study of diet and drug interactions on prostanoid metabolism. | 1985 | Prostaglandins | pmid:4034991 |
Wise WC et al. | Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock. | 1985 | Circ. Shock | pmid:3840416 |
Brace LD and Fareed J | An objective assessment of the interaction of heparin and its fractions with human platelets. | 1985 | Semin. Thromb. Hemost. | pmid:4035366 |
Demling RH et al. | Role of subcutaneous tissue endotoxin in the production of prostanoid-induced lung injury: comparison with intravenous endotoxin response. | 1985 | Circ. Shock | pmid:3840417 |
Takeda H et al. | [Early changes of vasoactive prostanoids in patients with mitral valve replacement]. | 1985 | Nihon Kyobu Geka Gakkai Zasshi | pmid:3840511 |
Shohami E and Gross J | An ex vivo method for evaluating prostaglandin synthetase activity in cortical slices of mouse brain. | 1985 | J. Neurochem. | pmid:3923156 |
Palmer RM and Salmon JA | Comparison of the effects of some compounds on human neutrophil degranulation and leukotriene B4 and thromboxane B2 synthesis. | 1985 | Biochem. Pharmacol. | pmid:2986647 |
Lynch TJ et al. | Carbon tetrachloride-induced eicosanoid synthesis and enzyme release from rat peritoneal leucocytes. | 1985 | Biochem. Pharmacol. | pmid:2986650 |
Armstrong RA et al. | Effect of the thromboxane receptor antagonist EP 092 on endotoxin shock in the sheep. | 1985 | Prostaglandins | pmid:2989977 |
Gay SW and Kosher RA | Prostaglandin synthesis during the course of limb cartilage differentiation in vitro. | 1985 | J Embryol Exp Morphol | pmid:3867724 |
Elliott GR et al. | Changes in resident rat peritoneal macrophage eicosanoid release, induced by altering the buffer K+/Na+ ratio, are Ca2+ dependent. | 1985 | Biochim. Biophys. Acta | pmid:3933563 |
Reines HD et al. | Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock. | 1985 | Surg Gynecol Obstet | pmid:3983796 |
Alessandrini P et al. | Physiologic variables affecting thromboxane B2 production in human whole blood. | 1985 | Thromb. Res. | pmid:3983893 |
Fukushima M et al. | [Role of thromboxane A2 in pulmonary air embolism in conscious sheep]. | 1985 | Kokyu To Junkan | pmid:4023449 |
Conti P et al. | Effect of supernatants from PHA-stimulated and non-stimulated lymphocyte cultures on thromboxane B2 release by polymorphonuclear leukocytes in vitro. | 1985 | Agents Actions | pmid:4003201 |
Carter AJ and Hanley SP | The effect of platelet number and haematocrit on whole blood thromboxane synthesis. | 1985 | Thromb. Haemost. | pmid:4024033 |
Kawaguchi A et al. | Increase in urinary thromboxane B2 in rats caused by cyclosporine. | 1985 | Transplantation | pmid:4024243 |