Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Cholecystitis, Acute D041881 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Thromboxane b2?

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What functions are associated with Thromboxane b2?


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What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Ahlsten G et al. Aggregation of and thromboxane B2 synthesis in platelets from newborn infants of smoking and non-smoking mothers. 1985 Prostaglandins Leukot Med pmid:3863152
Rosenkranz B and Frölich JC Plasma concentrations and anti-platelet effects after low dose acetylsalicylic acid. 1985 Prostaglandins Leukot Med pmid:3864170
Tooke JE et al. Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man. 1982 Prostaglandins Leukot Med pmid:6757966
Hall ER et al. Monoclonal antibody against TXB2: its use in solid and liquid phase radioimmunoassays. 1987 Prostaglandins Leukot Med pmid:3423097
Hornych A et al. Radioimmunoassay measurement of thromboxane B2 in human plasma and urine. 1982 Prostaglandins Leukot Med pmid:6954551
Mest HJ et al. Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. 1982 Prostaglandins Leukot Med pmid:6955811
Karmali RA et al. Macrophage production of prostaglandins: effects of fetal calf serum and diazepam. Use of an improved method for extracting 6-keto-PGF1 alpha. 1982 Prostaglandins Leukot Med pmid:6955812
Mehta J et al. Severe intracoronary thromboxane release preceding acute coronary artery occlusion. 1982 Prostaglandins Leukot Med pmid:6955814
Jaweed MM et al. Changes in thromboxane B2 and 6-keto-PGF1 alpha after direct electrical stimulation of the denervated rat gastrocnemius1,2. 1982 Prostaglandins Leukot Med pmid:6956927
Taube C et al. Enhanced thromboxane production in the aorta of spontaneously hypertensive rats in vitro. 1982 Prostaglandins Leukot Med pmid:6960370
Kazama Y et al. Reevaluation of circulating prostacyclin and thromboxane in diabetes. 1987 Prostaglandins Leukot Med pmid:3550820
Vlasses PH et al. Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6308685
Zavagli G et al. Platelet aggregation and evaluation of the ratio thromboxane B2/6-keto-prostaglandin F1 alpha in the plasma of patients on long term cimetidine treatment. 1985 Prostaglandins Leukot Med pmid:2997804
Dahl ML et al. Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets. 1983 Prostaglandins Leukot Med pmid:6415666
Chanh PH et al. Taurine and icosanoids in the heart. 1987 Prostaglandins Leukot Med pmid:3310012
Ali M and Afzal M A potent inhibitor of thrombin stimulated platelet thromboxane formation from unprocessed tea. 1987 Prostaglandins Leukot Med pmid:3473509
Kudo K et al. Urinary excretion of TXB2 after angiotensin converting enzyme inhibition in hypertensive patients. 1986 Prostaglandins Leukot Med pmid:3006084
Flynn JT Mechanism of complement-mediated thromboxane production by the perfused rabbit liver: lack of effect of dantrolene sodium. 1987 Prostaglandins Leukot Med pmid:3475728
Al-Hassan JM et al. Prostaglandin associated mortality following intravenous injection of catfish epidermal secretions in rabbits. 1987 Prostaglandins Leukot Med pmid:3475731
Brandt R et al. Effect of propranolol, practolol and atenolol on human platelet thromboxane formation and plasma levels of prostaglandins 6-keto-F1 alpha and E2. 1984 Prostaglandins Leukot Med pmid:6597450
Chiba S et al. Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: a possible pathophysiological role of TXA2 in the aged kidney. 1984 Prostaglandins Leukot Med pmid:6597456
Srivastava KC and Awasthi KK A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. 1982 Prostaglandins Leukot Med pmid:6818563
Pönicke K et al. Stimulation of aggregation and thromboxane A2 formation of human platelets by hypoxia. 1987 Prostaglandins Leukot Med pmid:3478738
Henriksson P et al. Increased aortic thromboxane production in experimental atherosclerosis. 1987 Prostaglandins Leukot Med pmid:3478739
Wilson L and Lindsey R Effects of progesterone withdrawal on uterine prostaglandin levels in the ovariectomized pregnant rat. 1987 Prostaglandins Leukot Med pmid:3478741
Semrad SD and Moore JN Effects of multiple low doses of flunixin meglumine on repeated endotoxin challenge in the horse. 1987 Prostaglandins Leukot Med pmid:3303061
Dore-Duffy P Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. 1982 Prostaglandins Leukot Med pmid:6281810
Valentovic MA and Lubawy WC Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. 1985 Prostaglandins Leukot Med pmid:3903777
Dahl ML and Uotila P Salicylate does not interfere with aspirin in human blood in vivo. 1984 Prostaglandins Leukot Med pmid:6585840
Dahl ML and Uotila P Thromboxane formation during blood clotting is decreased by verapamil. 1984 Prostaglandins Leukot Med pmid:6585842
Hall ER et al. The reduction of potential TXB2 levels when serum is preincubated at room temperature. 1984 Prostaglandins Leukot Med pmid:6585846
Srivastava KC Isolation and effects of some ginger components of platelet aggregation and eicosanoid biosynthesis. 1986 Prostaglandins Leukot Med pmid:3103137
Codde JP et al. Validation of the direct radioimmunoassay of prostanoids in serum and kidney. 1984 Prostaglandins Leukot Med pmid:6587406
Shaala S et al. Local effect of thromboxane B2 on the contractility of the human non pregnant uterus. 1984 Prostaglandins Leukot Med pmid:6587408
Meydani M et al. Effects of dietary methionine, methylmercury, and atrazine on ex-vivo synthesis of prostaglandin E1 and thromboxane B2. 1984 Prostaglandins Leukot Med pmid:6588393
Kääpä P Immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in neonatal hyperbilirubinemia. 1985 Prostaglandins Leukot Med pmid:3856285
Zijlstra FJ and Vincent JE Leukotriene D4 and phospholipase A2 release thromboxane A2 of different origin in the guinea pig lung parenchymal strip. 1985 Prostaglandins Leukot Med pmid:3857642
Hutchison AA et al. Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates. 1985 Prostaglandins Leukot Med pmid:3859877
Gallon LS and Barcelli UO Measurement of prostaglandin E3 and other eicosanoids in biologic samples using high pressure liquid chromatography and radioimmunoassay. 1986 Prostaglandins pmid:3961201
Honstra G et al. Influence of dietary fish on eicosanoid metabolism in man. 1990 Prostaglandins pmid:2123355
Morley J et al. Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. 1979 Prostaglandins pmid:493559
de Deckere EA et al. Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. 1979 Prostaglandins pmid:504696
Spagnuolo C et al. Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. 1979 Prostaglandins pmid:523683
Lorenz R et al. A new method using simple solid phase extraction for the rapid gas-chromatographic mass-spectrometric determination of 11-dehydro-thromboxane B2 in urine. 1989 Prostaglandins pmid:2772221
Mitrovic D et al. The in vitro production of prostanoids by cultured bovine articular chondrocytes. 1982 Prostaglandins pmid:6801735
Anhut H et al. Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. 1978 Prostaglandins pmid:704912
Lihrmann I et al. Role of prostaglandins in calcium-induced corticosteroid secretion by isolated frog interrenal gland. 1986 Prostaglandins pmid:3464040
Nelson NA et al. Synthesis of thromboxane B2 metabolites. 1978 Prostaglandins pmid:704927
Marion J and Wolfe LS Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. 1978 Prostaglandins pmid:704928
Kitchen EA et al. Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. 1978 Prostaglandins pmid:704931
Sors H et al. Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. 1978 Prostaglandins pmid:704933
Turk J et al. Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. 1978 Prostaglandins pmid:704934
Daniel EE et al. Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. 1979 Prostaglandins pmid:379920
Kuzan FB et al. Role of spermatozoal platelet-activating factor in fertilization. 1990 Prostaglandins pmid:2155438
Kennedy MS et al. In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. 1980 Prostaglandins pmid:6967616
Russell FA and Deykin D The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. 1979 Prostaglandins pmid:523671
Dembinska-Kiec A et al. The effects of platelet-activating factor on flow rate and eicosanoid release in the isolated perfused rat gastric vascular bed. 1989 Prostaglandins pmid:2717778
Eskew ML et al. Effects of inadequate vitamin E and/or selenium nutrition on the release of arachidonic acid metabolites in rat alveolar macrophages. 1989 Prostaglandins pmid:2546191
Yang DS et al. Effects of 3,4-dihydroxyacetophenone on the biosynthesis of TXA2 and PGI2 in human placental villus and umbilical artery segments in vitro. 1989 Prostaglandins pmid:2510216
Bjøro K et al. Altered prostanoid formation in human umbilical vasculature in response to variations in oxygen tension. 1987 Prostaglandins pmid:3432554
Noort WA et al. Increase in urinary thromboxane excretion during pregnancy and labor. 1987 Prostaglandins pmid:3432555
Mehta P et al. Comparison of umbilical vein models for measurement of relative prostacyclin and thromboxane production. 1982 Prostaglandins pmid:6820165
Nolan RD et al. The pericardium as a source of prostacyclin in the dog, ox and rat. 1982 Prostaglandins pmid:6820168
Koyama I et al. Release of 6-keto-prostaglandin F1 alpha and thromboxane B2 from mouse peritoneal macrophages during their adhesion and spreading on a glass surface. 1982 Prostaglandins pmid:6896924
Stichtenoth DO et al. Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. 1995 Nov-Dec Prostaglandins pmid:8838242
Schaefer WR et al. Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat. 1996 Prostaglandins pmid:8875634
Eskew ML et al. Increased thromboxane A2 synthesis by rat lung neutrophils during selenium deficiency. 1993 Prostaglandins pmid:8248545
Bertazzo A et al. The carbochromene derivative AD6 reduces the TxB2/6-keto-PGF1 alpha ratio in cerebral cortex during hypoxia and recovery and leukotriene synthesis in brain tissue, in the rat. 1988 Prostaglandins pmid:2836887
Walenga RW et al. Time-dependent inhibition of platelet cyclooxygenase by indomethacin is slowly reversible. 1986 Prostaglandins pmid:3088675
Feddersen CO et al. Acetylcholine induces vasodilation and prostacyclin synthesis in rat lungs. 1986 Prostaglandins pmid:3088679
Nadasy GL et al. Pharmacological modulation of prostacyclin and thromboxane production of rat and cat venous tissue slices. 1992 Prostaglandins pmid:1438884
Myers SI et al. Increased intragallbladder pressure stimulates gallbladder eicosanoid release. 1994 Prostaglandins pmid:7972880
Muller M and Sorrell TC Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. 1995 Nov-Dec Prostaglandins pmid:8838240
MacDermot J et al. Synthesis of leukotriene B4, and prostanoids by human alveolar macrophages: analysis by gas chromatography/mass spectrometry. 1984 Prostaglandins pmid:6326199
Muccitelli RM et al. Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. 1983 Prostaglandins pmid:6689082
Calò L et al. Arachidonic acid metabolites in a nephroblastoma associated with paraneoplastic hypercalcemia. 1986 Prostaglandins pmid:3020618
McNamara DB et al. Prostaglandin endoperoxide metabolism by microsomes of whole kidneys from normal, congenital unilateral hydronephrotic and unilateral ureteral obstructed rats. 1982 Prostaglandins pmid:6962465
Westlund P et al. Identification of 11-dehydro-TXB2 as a suitable parameter for monitoring thromboxane production in the human. 1986 Prostaglandins pmid:3755250
Siler-Khodr TM and Forman J Effect of IGF-1 on placental prostanoid production. 1993 Prostaglandins pmid:8248549
Bryant RW and Hwang DH Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. 1983 Prostaglandins pmid:6419285
Stier CT et al. Enhanced thromboxane formation by blood but not whole platelets from spontaneously hypertensive rats. 1992 Prostaglandins pmid:1410518
Peskar BM et al. Effects of pure enantiomers of flurbiprofen in comparison to racemic flurbiprofen on eicosanoid release from various rat organs ex vivo. 1991 Prostaglandins pmid:1801061
Torres-Duarte A and Amezcua JL Thromboxane and prostacyclin generation by human umbilical veins after thrombin. 1991 Prostaglandins pmid:1801064
Myers SI and Hernandez R Role of oxygen-derived free radicals on rat splanchnic eicosanoid production during acute hemorrhage. 1992 Prostaglandins pmid:1641500
Hsu P et al. Effects of ischemia/reperfusion on brain tissue prostanoids and leukotrienes in newborn pigs. 1991 Prostaglandins pmid:1666191
Shohami E and Feuerstein G T-2 toxemia and brain prostaglandins. 1986 Prostaglandins pmid:3457405
Foegh ML et al. Coronary artery thrombosis and elevated urine immunoreactive thromboxane B2. 1986 Prostaglandins pmid:3823490
Hotter G et al. Prostaglandin E2 and thromboxane B2 levels in rats subjected to pancreas transplantation. 1990 Prostaglandins pmid:2309043
Fylling AC et al. Kinetic and structural evidence for the identification of 11-hydroxythromboxane B2 dehydrogenase as cytosolic aldehyde dehydrogenase. 1995 Nov-Dec Prostaglandins pmid:8838239
Homo-Delarche F et al. In vitro inhibition of prostaglandin production by azathioprine and 6-mercaptopurine. 1988 Prostaglandins pmid:3247467
de la Hunt MN et al. Modification of upper gastrointestinal prostaglandin synthesis by dietary fatty acids. 1988 Prostaglandins pmid:3247473
Tulenko TN The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. 1981 Prostaglandins pmid:6794096
Spurney RF et al. Physiologic role for enhanced renal thromboxane production in murine lupus nephritis. 1991 Prostaglandins pmid:1771236
Morello A et al. A chemiluminescent immunoassay for urinary thromboxane B2. 1991 Prostaglandins pmid:1771240
Schafer W et al. Urinary excretion of 6-keto-PGF1 alpha TxB2 and PGE2 in a rat animal model for preeclampsia-like syndrome. 1993 Prostaglandins pmid:8210446
Kunkel SL et al. Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors. 1982 Prostaglandins pmid:6300969
Harada Y et al. Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry. 1982 Prostaglandins pmid:6889754
Scherhag R et al. Dietary administration of eicosapentaenoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in the rat. 1982 Prostaglandins pmid:6285420
Satoh H et al. Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. 1981 Prostaglandins pmid:7197382
Freed MS et al. Essential fatty acid deficiency inhibits early but not late leukocyte infiltration in rabbit myocardial infarcts. 1989 Prostaglandins pmid:2546188