MeSH term | MeSH ID | Detail |
---|---|---|
Cholecystitis, Acute | D041881 | 1 associated lipids |
Gastric Dilatation | D013271 | 1 associated lipids |
Stomach Volvulus | D013277 | 1 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ahlsten G et al. | Aggregation of and thromboxane B2 synthesis in platelets from newborn infants of smoking and non-smoking mothers. | 1985 | Prostaglandins Leukot Med | pmid:3863152 |
Rosenkranz B and Frölich JC | Plasma concentrations and anti-platelet effects after low dose acetylsalicylic acid. | 1985 | Prostaglandins Leukot Med | pmid:3864170 |
Tooke JE et al. | Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man. | 1982 | Prostaglandins Leukot Med | pmid:6757966 |
Hall ER et al. | Monoclonal antibody against TXB2: its use in solid and liquid phase radioimmunoassays. | 1987 | Prostaglandins Leukot Med | pmid:3423097 |
Hornych A et al. | Radioimmunoassay measurement of thromboxane B2 in human plasma and urine. | 1982 | Prostaglandins Leukot Med | pmid:6954551 |
Mest HJ et al. | Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. | 1982 | Prostaglandins Leukot Med | pmid:6955811 |
Karmali RA et al. | Macrophage production of prostaglandins: effects of fetal calf serum and diazepam. Use of an improved method for extracting 6-keto-PGF1 alpha. | 1982 | Prostaglandins Leukot Med | pmid:6955812 |
Mehta J et al. | Severe intracoronary thromboxane release preceding acute coronary artery occlusion. | 1982 | Prostaglandins Leukot Med | pmid:6955814 |
Jaweed MM et al. | Changes in thromboxane B2 and 6-keto-PGF1 alpha after direct electrical stimulation of the denervated rat gastrocnemius1,2. | 1982 | Prostaglandins Leukot Med | pmid:6956927 |
Taube C et al. | Enhanced thromboxane production in the aorta of spontaneously hypertensive rats in vitro. | 1982 | Prostaglandins Leukot Med | pmid:6960370 |
Kazama Y et al. | Reevaluation of circulating prostacyclin and thromboxane in diabetes. | 1987 | Prostaglandins Leukot Med | pmid:3550820 |
Vlasses PH et al. | Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. | 1983 | Prostaglandins Leukot Med | pmid:6308685 |
Zavagli G et al. | Platelet aggregation and evaluation of the ratio thromboxane B2/6-keto-prostaglandin F1 alpha in the plasma of patients on long term cimetidine treatment. | 1985 | Prostaglandins Leukot Med | pmid:2997804 |
Dahl ML et al. | Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets. | 1983 | Prostaglandins Leukot Med | pmid:6415666 |
Chanh PH et al. | Taurine and icosanoids in the heart. | 1987 | Prostaglandins Leukot Med | pmid:3310012 |
Ali M and Afzal M | A potent inhibitor of thrombin stimulated platelet thromboxane formation from unprocessed tea. | 1987 | Prostaglandins Leukot Med | pmid:3473509 |
Kudo K et al. | Urinary excretion of TXB2 after angiotensin converting enzyme inhibition in hypertensive patients. | 1986 | Prostaglandins Leukot Med | pmid:3006084 |
Flynn JT | Mechanism of complement-mediated thromboxane production by the perfused rabbit liver: lack of effect of dantrolene sodium. | 1987 | Prostaglandins Leukot Med | pmid:3475728 |
Al-Hassan JM et al. | Prostaglandin associated mortality following intravenous injection of catfish epidermal secretions in rabbits. | 1987 | Prostaglandins Leukot Med | pmid:3475731 |
Brandt R et al. | Effect of propranolol, practolol and atenolol on human platelet thromboxane formation and plasma levels of prostaglandins 6-keto-F1 alpha and E2. | 1984 | Prostaglandins Leukot Med | pmid:6597450 |
Chiba S et al. | Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: a possible pathophysiological role of TXA2 in the aged kidney. | 1984 | Prostaglandins Leukot Med | pmid:6597456 |
Srivastava KC and Awasthi KK | A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. | 1982 | Prostaglandins Leukot Med | pmid:6818563 |
Pönicke K et al. | Stimulation of aggregation and thromboxane A2 formation of human platelets by hypoxia. | 1987 | Prostaglandins Leukot Med | pmid:3478738 |
Henriksson P et al. | Increased aortic thromboxane production in experimental atherosclerosis. | 1987 | Prostaglandins Leukot Med | pmid:3478739 |
Wilson L and Lindsey R | Effects of progesterone withdrawal on uterine prostaglandin levels in the ovariectomized pregnant rat. | 1987 | Prostaglandins Leukot Med | pmid:3478741 |
Semrad SD and Moore JN | Effects of multiple low doses of flunixin meglumine on repeated endotoxin challenge in the horse. | 1987 | Prostaglandins Leukot Med | pmid:3303061 |
Dore-Duffy P | Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. | 1982 | Prostaglandins Leukot Med | pmid:6281810 |
Valentovic MA and Lubawy WC | Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. | 1985 | Prostaglandins Leukot Med | pmid:3903777 |
Dahl ML and Uotila P | Salicylate does not interfere with aspirin in human blood in vivo. | 1984 | Prostaglandins Leukot Med | pmid:6585840 |
Dahl ML and Uotila P | Thromboxane formation during blood clotting is decreased by verapamil. | 1984 | Prostaglandins Leukot Med | pmid:6585842 |
Hall ER et al. | The reduction of potential TXB2 levels when serum is preincubated at room temperature. | 1984 | Prostaglandins Leukot Med | pmid:6585846 |
Srivastava KC | Isolation and effects of some ginger components of platelet aggregation and eicosanoid biosynthesis. | 1986 | Prostaglandins Leukot Med | pmid:3103137 |
Codde JP et al. | Validation of the direct radioimmunoassay of prostanoids in serum and kidney. | 1984 | Prostaglandins Leukot Med | pmid:6587406 |
Shaala S et al. | Local effect of thromboxane B2 on the contractility of the human non pregnant uterus. | 1984 | Prostaglandins Leukot Med | pmid:6587408 |
Meydani M et al. | Effects of dietary methionine, methylmercury, and atrazine on ex-vivo synthesis of prostaglandin E1 and thromboxane B2. | 1984 | Prostaglandins Leukot Med | pmid:6588393 |
Kääpä P | Immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in neonatal hyperbilirubinemia. | 1985 | Prostaglandins Leukot Med | pmid:3856285 |
Zijlstra FJ and Vincent JE | Leukotriene D4 and phospholipase A2 release thromboxane A2 of different origin in the guinea pig lung parenchymal strip. | 1985 | Prostaglandins Leukot Med | pmid:3857642 |
Hutchison AA et al. | Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates. | 1985 | Prostaglandins Leukot Med | pmid:3859877 |
Gallon LS and Barcelli UO | Measurement of prostaglandin E3 and other eicosanoids in biologic samples using high pressure liquid chromatography and radioimmunoassay. | 1986 | Prostaglandins | pmid:3961201 |
Honstra G et al. | Influence of dietary fish on eicosanoid metabolism in man. | 1990 | Prostaglandins | pmid:2123355 |
Morley J et al. | Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. | 1979 | Prostaglandins | pmid:493559 |
de Deckere EA et al. | Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. | 1979 | Prostaglandins | pmid:504696 |
Spagnuolo C et al. | Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. | 1979 | Prostaglandins | pmid:523683 |
Lorenz R et al. | A new method using simple solid phase extraction for the rapid gas-chromatographic mass-spectrometric determination of 11-dehydro-thromboxane B2 in urine. | 1989 | Prostaglandins | pmid:2772221 |
Mitrovic D et al. | The in vitro production of prostanoids by cultured bovine articular chondrocytes. | 1982 | Prostaglandins | pmid:6801735 |
Anhut H et al. | Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. | 1978 | Prostaglandins | pmid:704912 |
Lihrmann I et al. | Role of prostaglandins in calcium-induced corticosteroid secretion by isolated frog interrenal gland. | 1986 | Prostaglandins | pmid:3464040 |
Nelson NA et al. | Synthesis of thromboxane B2 metabolites. | 1978 | Prostaglandins | pmid:704927 |
Marion J and Wolfe LS | Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. | 1978 | Prostaglandins | pmid:704928 |
Kitchen EA et al. | Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. | 1978 | Prostaglandins | pmid:704931 |
Sors H et al. | Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. | 1978 | Prostaglandins | pmid:704933 |
Turk J et al. | Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. | 1978 | Prostaglandins | pmid:704934 |
Daniel EE et al. | Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. | 1979 | Prostaglandins | pmid:379920 |
Kuzan FB et al. | Role of spermatozoal platelet-activating factor in fertilization. | 1990 | Prostaglandins | pmid:2155438 |
Kennedy MS et al. | In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. | 1980 | Prostaglandins | pmid:6967616 |
Russell FA and Deykin D | The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. | 1979 | Prostaglandins | pmid:523671 |
Dembinska-Kiec A et al. | The effects of platelet-activating factor on flow rate and eicosanoid release in the isolated perfused rat gastric vascular bed. | 1989 | Prostaglandins | pmid:2717778 |
Eskew ML et al. | Effects of inadequate vitamin E and/or selenium nutrition on the release of arachidonic acid metabolites in rat alveolar macrophages. | 1989 | Prostaglandins | pmid:2546191 |
Yang DS et al. | Effects of 3,4-dihydroxyacetophenone on the biosynthesis of TXA2 and PGI2 in human placental villus and umbilical artery segments in vitro. | 1989 | Prostaglandins | pmid:2510216 |
Bjøro K et al. | Altered prostanoid formation in human umbilical vasculature in response to variations in oxygen tension. | 1987 | Prostaglandins | pmid:3432554 |
Noort WA et al. | Increase in urinary thromboxane excretion during pregnancy and labor. | 1987 | Prostaglandins | pmid:3432555 |
Mehta P et al. | Comparison of umbilical vein models for measurement of relative prostacyclin and thromboxane production. | 1982 | Prostaglandins | pmid:6820165 |
Nolan RD et al. | The pericardium as a source of prostacyclin in the dog, ox and rat. | 1982 | Prostaglandins | pmid:6820168 |
Koyama I et al. | Release of 6-keto-prostaglandin F1 alpha and thromboxane B2 from mouse peritoneal macrophages during their adhesion and spreading on a glass surface. | 1982 | Prostaglandins | pmid:6896924 |
Stichtenoth DO et al. | Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. | 1995 Nov-Dec | Prostaglandins | pmid:8838242 |
Schaefer WR et al. | Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat. | 1996 | Prostaglandins | pmid:8875634 |
Eskew ML et al. | Increased thromboxane A2 synthesis by rat lung neutrophils during selenium deficiency. | 1993 | Prostaglandins | pmid:8248545 |
Bertazzo A et al. | The carbochromene derivative AD6 reduces the TxB2/6-keto-PGF1 alpha ratio in cerebral cortex during hypoxia and recovery and leukotriene synthesis in brain tissue, in the rat. | 1988 | Prostaglandins | pmid:2836887 |
Walenga RW et al. | Time-dependent inhibition of platelet cyclooxygenase by indomethacin is slowly reversible. | 1986 | Prostaglandins | pmid:3088675 |
Feddersen CO et al. | Acetylcholine induces vasodilation and prostacyclin synthesis in rat lungs. | 1986 | Prostaglandins | pmid:3088679 |
Nadasy GL et al. | Pharmacological modulation of prostacyclin and thromboxane production of rat and cat venous tissue slices. | 1992 | Prostaglandins | pmid:1438884 |
Myers SI et al. | Increased intragallbladder pressure stimulates gallbladder eicosanoid release. | 1994 | Prostaglandins | pmid:7972880 |
Muller M and Sorrell TC | Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. | 1995 Nov-Dec | Prostaglandins | pmid:8838240 |
MacDermot J et al. | Synthesis of leukotriene B4, and prostanoids by human alveolar macrophages: analysis by gas chromatography/mass spectrometry. | 1984 | Prostaglandins | pmid:6326199 |
Muccitelli RM et al. | Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. | 1983 | Prostaglandins | pmid:6689082 |
Calò L et al. | Arachidonic acid metabolites in a nephroblastoma associated with paraneoplastic hypercalcemia. | 1986 | Prostaglandins | pmid:3020618 |
McNamara DB et al. | Prostaglandin endoperoxide metabolism by microsomes of whole kidneys from normal, congenital unilateral hydronephrotic and unilateral ureteral obstructed rats. | 1982 | Prostaglandins | pmid:6962465 |
Westlund P et al. | Identification of 11-dehydro-TXB2 as a suitable parameter for monitoring thromboxane production in the human. | 1986 | Prostaglandins | pmid:3755250 |
Siler-Khodr TM and Forman J | Effect of IGF-1 on placental prostanoid production. | 1993 | Prostaglandins | pmid:8248549 |
Bryant RW and Hwang DH | Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. | 1983 | Prostaglandins | pmid:6419285 |
Stier CT et al. | Enhanced thromboxane formation by blood but not whole platelets from spontaneously hypertensive rats. | 1992 | Prostaglandins | pmid:1410518 |
Peskar BM et al. | Effects of pure enantiomers of flurbiprofen in comparison to racemic flurbiprofen on eicosanoid release from various rat organs ex vivo. | 1991 | Prostaglandins | pmid:1801061 |
Torres-Duarte A and Amezcua JL | Thromboxane and prostacyclin generation by human umbilical veins after thrombin. | 1991 | Prostaglandins | pmid:1801064 |
Myers SI and Hernandez R | Role of oxygen-derived free radicals on rat splanchnic eicosanoid production during acute hemorrhage. | 1992 | Prostaglandins | pmid:1641500 |
Hsu P et al. | Effects of ischemia/reperfusion on brain tissue prostanoids and leukotrienes in newborn pigs. | 1991 | Prostaglandins | pmid:1666191 |
Shohami E and Feuerstein G | T-2 toxemia and brain prostaglandins. | 1986 | Prostaglandins | pmid:3457405 |
Foegh ML et al. | Coronary artery thrombosis and elevated urine immunoreactive thromboxane B2. | 1986 | Prostaglandins | pmid:3823490 |
Hotter G et al. | Prostaglandin E2 and thromboxane B2 levels in rats subjected to pancreas transplantation. | 1990 | Prostaglandins | pmid:2309043 |
Fylling AC et al. | Kinetic and structural evidence for the identification of 11-hydroxythromboxane B2 dehydrogenase as cytosolic aldehyde dehydrogenase. | 1995 Nov-Dec | Prostaglandins | pmid:8838239 |
Homo-Delarche F et al. | In vitro inhibition of prostaglandin production by azathioprine and 6-mercaptopurine. | 1988 | Prostaglandins | pmid:3247467 |
de la Hunt MN et al. | Modification of upper gastrointestinal prostaglandin synthesis by dietary fatty acids. | 1988 | Prostaglandins | pmid:3247473 |
Tulenko TN | The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. | 1981 | Prostaglandins | pmid:6794096 |
Spurney RF et al. | Physiologic role for enhanced renal thromboxane production in murine lupus nephritis. | 1991 | Prostaglandins | pmid:1771236 |
Morello A et al. | A chemiluminescent immunoassay for urinary thromboxane B2. | 1991 | Prostaglandins | pmid:1771240 |
Schafer W et al. | Urinary excretion of 6-keto-PGF1 alpha TxB2 and PGE2 in a rat animal model for preeclampsia-like syndrome. | 1993 | Prostaglandins | pmid:8210446 |
Kunkel SL et al. | Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors. | 1982 | Prostaglandins | pmid:6300969 |
Harada Y et al. | Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry. | 1982 | Prostaglandins | pmid:6889754 |
Scherhag R et al. | Dietary administration of eicosapentaenoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in the rat. | 1982 | Prostaglandins | pmid:6285420 |
Satoh H et al. | Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. | 1981 | Prostaglandins | pmid:7197382 |
Freed MS et al. | Essential fatty acid deficiency inhibits early but not late leukocyte infiltration in rabbit myocardial infarcts. | 1989 | Prostaglandins | pmid:2546188 |