MeSH term | MeSH ID | Detail |
---|---|---|
Cholecystitis, Acute | D041881 | 1 associated lipids |
Gastric Dilatation | D013271 | 1 associated lipids |
Stomach Volvulus | D013277 | 1 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ahlsten G et al. | Aggregation of and thromboxane B2 synthesis in platelets from newborn infants of smoking and non-smoking mothers. | 1985 | Prostaglandins Leukot Med | pmid:3863152 |
Rosenkranz B and Frölich JC | Plasma concentrations and anti-platelet effects after low dose acetylsalicylic acid. | 1985 | Prostaglandins Leukot Med | pmid:3864170 |
Myśliwiec M et al. | Plasma thromboxane B2 in haemodialysed patients. | 1985 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2414174 |
Luzzatto G et al. | PF 4 versus beta TG as evidence for platelet activation in myeloproliferative disorders. | 1985 | Scand J Haematol | pmid:2414843 |
Papanicolaou N et al. | Selective inhibition of renal thromboxane biosynthesis increased sodium excretion rate in normal and saline-loaded rats. | 1985 | Clin. Sci. | pmid:3880524 |
Hänsch GM et al. | Induction of prostanoid synthesis in human platelets by the late complement components C5b-9 and channel forming antibiotic nystatin: inhibition of the reacylation of liberated arachidonic acid. | 1985 | J. Immunol. | pmid:2409145 |
Yajima M et al. | Plasma thromboxane B2, 6-keto PGF1 alpha and cyclic nucleotides levels as related to treadmill exercise test in patients with ischemic heart disease. | 1985 | Jpn. Circ. J. | pmid:2982050 |
Fiedler VB et al. | Leukotrienes on porcine hemodynamics and prostanoid release. | 1985 | Int. J. Cardiol. | pmid:2993176 |
Brown EM and Swartz SL | Production of prostaglandins by dispersed cells and fragments from bovine parathyroid glands. | 1985 | Prostaglandins | pmid:3883430 |
Hugli TE and Marceau F | Effects of the C5a anaphylatoxin and its relationship to cyclo-oxygenase metabolites in rabbit vascular strips. | 1985 | Br. J. Pharmacol. | pmid:3921089 |
Boraschi D et al. | Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons. | 1985 | J. Immunol. | pmid:3923110 |
Ment LR et al. | Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants. | 1985 | J. Pediatr. | pmid:3906073 |
Slotman GJ et al. | Thromboxane, prostacyclin, and the hemodynamic effects of graded bacteremic shock. | 1985 | Circ. Shock | pmid:3915237 |
Walsh SW | Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. | 1985 | Am. J. Obstet. Gynecol. | pmid:3923838 |
Bowers GJ et al. | Prostanoid production by lipopolysaccharide-stimulated Kupffer cells. | 1985 | J. Surg. Res. | pmid:3887037 |
Kiyomiya K and Oh-ishi S | Involvement of arachidonic acid metabolites in acute inflammation: detection of 6-keto-PGF1 alpha, thromboxane B2 and PGD2 in rat pleurisy induced by phorbol myristate acetate. | 1985 | Jpn. J. Pharmacol. | pmid:3936958 |
Stenmark KR et al. | Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. | 1985 | Am. J. Physiol. | pmid:3923843 |
Quilley J and McGiff JC | Arachidonic acid metabolism and urinary excretion of prostaglandins and thromboxane in rats with experimental diabetes mellitus. | 1985 | J. Pharmacol. Exp. Ther. | pmid:3925127 |
Yamaguchi M and Mori N | 6-Keto prostaglandin F1 alpha, thromboxane B2, and 13,14-dihydro-15-keto prostaglandin F concentrations of normotensive and preeclamptic patients during pregnancy, delivery, and the postpartum period. | 1985 | Am. J. Obstet. Gynecol. | pmid:3838119 |
O'Keefe EH et al. | Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro. | 1985 | Prostaglandins | pmid:3925501 |
Glance DG et al. | Prostaglandin production and stimulation by angiotensin II in the isolated perfused human placental cotyledon. | 1985 | Am. J. Obstet. Gynecol. | pmid:3855602 |
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Gee MH et al. | Eicosanoids, leukocytes and lung injury. | 1985 | Prog. Clin. Biol. Res. | pmid:3934681 |
Shono F et al. | A solid-phase enzyme immunoassay of thromboxane B2. | 1985 | J. Biochem. | pmid:3935648 |
Wang JP et al. | Antiplatelet effect of hsien-ho-t'sao (Agrimonia pilosa). | 1985 | Am. J. Chin. Med. | pmid:3927704 |
Greer IA et al. | Platelet activation in allergic asthma. | 1985 | Thromb. Haemost. | pmid:2931855 |
Safai-Kutti S et al. | Impaired in vivo platelet reactivity in infantile autism. | 1985 | Acta Paediatr Scand | pmid:2931944 |
Mikhailidis DP et al. | Heparin-induced platelet aggregation in anorexia nervosa and in severe peripheral vascular disease. | 1985 | Eur. J. Clin. Invest. | pmid:3938401 |
Meese CO et al. | Measurement of thromboxane B2 in human urine by isotope dilution and negative ion chemical ionization mass spectrometry. | 1985 | Biomed. Mass Spectrom. | pmid:2932184 |
Boss AH et al. | Effect of incremental doses of aspirin on bleeding time, platelet aggregation and thromboxane production in patients with cerebrovascular disease. | 1985 | Eur. J. Clin. Invest. | pmid:3938412 |
Ambler J et al. | CGS 12970: a novel, long acting thromboxane synthetase inhibitor. | 1985 | Br. J. Pharmacol. | pmid:2932197 |
Gresele P et al. | Thromboxane A2 and prostacyclin do not modulate the systemic hemodynamic response to cold in humans. | 1985 | J. Lab. Clin. Med. | pmid:2932514 |
Hashimoto Y et al. | Time-dependent inhibition of the cyclooxygenase pathway by 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3927909 |
Mueller HS et al. | Systemic and transcardiac platelet activity in acute myocardial infarction in man: resistance to prostacyclin. | 1985 | Circulation | pmid:2933181 |
Hakim RM and Schafer AI | Hemodialysis-associated platelet activation and thrombocytopenia. | 1985 | Am. J. Med. | pmid:3885730 |
Howes EL et al. | Lipopolysaccharide tolerance inhibits eye inflammation. I. Reduced immune complex or lipopolysaccharide effects. | 1985 | Arch. Ophthalmol. | pmid:3156578 |
Jouppila P et al. | Ritodrine infusion during late pregnancy: effects on fetal and placental blood flow, prostacyclin, and thromboxane. | 1985 | Am. J. Obstet. Gynecol. | pmid:3885740 |
Davì G et al. | Inhibition of platelet function by ticlopidine in arteriosclerosis obliterans of the lower limbs. | 1985 | Thromb. Res. | pmid:2933846 |
Bloom A et al. | Hemolytic-uremic syndrome: demonstration of abnormalities of platelet reactivity and insensitivity to prostaglandin I2. | 1985 | Clin. Nephrol. | pmid:3886228 |
Meyrick B et al. | Endothelial prostacyclin production is a late event in granulocyte migration into bovine pulmonary artery intimal explants. | 1985 | Blood | pmid:3904871 |
Janka HU | Platelet and endothelial function tests during metformin treatment in diabetes mellitus (short communication). | 1985 | Horm. Metab. Res. Suppl. | pmid:2934311 |
Hayashi C | [Thromboxane B2 in surgery]. | 1985 | Nihon Geka Gakkai Zasshi | pmid:2935731 |
Steinhauer HB et al. | Thromboxane B2 and beta 2-microglobulin as early indicators of renal allograft rejection. | 1985 | Proc Eur Dial Transplant Assoc Eur Ren Assoc | pmid:3887370 |
Lenhard V et al. | Transfusion-induced enhancement of prostaglandin and thromboxane release in prospective kidney graft recipients. | 1985 | Proc Eur Dial Transplant Assoc Eur Ren Assoc | pmid:3887386 |
Naesh O et al. | Platelet function in surgical stress. | 1985 | Thromb. Haemost. | pmid:2935969 |
Takahata K et al. | [Effect of PSK on prostaglandin metabolism (I)]. | 1985 | Gan To Kagaku Ryoho | pmid:3888117 |
McGowan HM et al. | The effect of dietary alteration of prostaglandin synthesis on blood pressure and the reversal of hypertension in the one-kidney, one-clip rat. | 1985 | Prostaglandins | pmid:3859891 |
Pedersen AK and FitzGerald GA | Cyclooxygenase inhibition, platelet function, and metabolite formation during chronic sulfinpyrazone dosing. | 1985 | Clin. Pharmacol. Ther. | pmid:3917387 |
von Schacky C et al. | Long-term effects of dietary marine omega-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans. | 1985 | J. Clin. Invest. | pmid:2997286 |
Barst RJ et al. | Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child. | 1985 | Am. Rev. Respir. Dis. | pmid:3917630 |
Stuart MJ and Dusse J | In vitro comparison of the efficacy of cyclooxygenase inhibitors on the adult versus neonatal platelet. | 1985 | Biol. Neonate | pmid:4005330 |
Amado JA et al. | Influence of acetylsalicylic acid on bleeding time and serum thromboxane B2 in diabetes mellitus type I. | 1985 | Diabete Metab | pmid:4007228 |
Moncada S and Whittle BJ | Biological actions of prostacyclin and its pharmacological use in platelet studies. | 1985 | Adv. Exp. Med. Biol. | pmid:3010671 |
De Servi S et al. | [Myocardial ischemia during exertion. Correlations between blood levels of thromboxane B2 and changes in coronary flow and resistance]. | 1985 | G Ital Cardiol | pmid:4007353 |
Halenda SP et al. | Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187. | 1985 | J. Biol. Chem. | pmid:3930496 |
De Caterina R et al. | Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:3159210 |
Trimarco B et al. | Indomethacin blunts the late phase of nitroglycerin-induced coronary vasodilatation in dogs. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:3159220 |
Shikano M et al. | Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:3159226 |
Prosdocimi M et al. | Prostacyclin and thromboxane levels during cardiac ischemia in dogs. | 1985 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:3159235 |
Stine RA et al. | Failure of percutaneous transluminal coronary angioplasty to stimulate platelet and prostaglandin activity. | 1985 | Cathet Cardiovasc Diagn | pmid:3160477 |
Liu MC et al. | Studies of platelet hyperactivity in patients with ischemic cerebrovascular diseases. III. Platelet hyperactivation in the chronic phase of cerebral thromboembolism. | 1985 | Taiwan Yi Xue Hui Za Zhi | pmid:3160819 |
Hechtman DH and Jageneau A | Inhibition of cold-induced vasoconstriction with ketanserin. | 1985 | Microvasc. Res. | pmid:3160915 |
Yamaguchi A et al. | Effect of cetiedil on platelet aggregation and thromboxane synthesis. | 1985 | Thromb. Res. | pmid:2986312 |
Utsunomiya T et al. | [Circulating negative inotropic substance produced by the lung, affected by prostaglandin and thromboxane]. | 1985 | Nihon Geka Gakkai Zasshi | pmid:3160927 |
Wang CB and Chang AM | [Plasma thromboxane B2 changes in severe icteric hepatitis treated by traditional Chinese medicine--dispelling the pathogenic heat from blood, promoting blood circulation and administrating large doses of radix Paeoniae--a report of 6 cases]. | 1985 | Zhong Xi Yi Jie He Za Zhi | pmid:3161645 |
Mendieta CF et al. | Biosynthesis of prostaglandins in gingiva of patients with chronic periodontitis. | 1985 | J. Periodontol. | pmid:3919173 |
Galli C et al. | Modification of brain vascular eicosanoids after pharmacological treatment and ischemia in the rat: drugs and brain vascular eicosanoids. | 1985 | Cephalalgia | pmid:3839438 |
Casey LC et al. | The role of thromboxane in primate endotoxin shock. | 1985 | J. Surg. Res. | pmid:3839548 |
Jindal SK et al. | Regulation of increase in anastomotic blood flow following pulmonary arterial occlusion. | 1985 | J. Appl. Physiol. | pmid:3839787 |
Narita H et al. | Insufficient mobilization of calcium by early breakdown of phosphatidylinositol 4,5-bisphosphate for aggregation of human platelets by collagen. | 1985 | J. Biochem. | pmid:3001036 |
Garrett RC and Thomas HM | Relation of prostanoids to strength of hypoxic vasoconstriction in dogs with lobar atelectasis. | 1985 | J. Appl. Physiol. | pmid:3839788 |
Horiuchi Y et al. | [Studies on changes in histamine levels in the blood of infants and children. Part 7. The time studies of histamine, lipoxygenase metabolites, thromboxe B2 and cyclic AMP release from human platelets and leucocytes on treadmill exercise in asthmatic children]. | 1985 | Arerugi | pmid:3002304 |
Giani E et al. | Heated fat, vitamin E and vascular eicosanoids. | 1985 | Lipids | pmid:3839887 |
Giani E et al. | Platelets from aged rats aggregate more, but are more sensitive to prostacyclin. | 1985 | Prostaglandins Leukot Med | pmid:3003760 |
Ikkala E et al. | Haemostatic parameters in Cushing's syndrome. | 1985 | Acta Med Scand | pmid:4025006 |
Sylvester JT et al. | Prostaglandins and estradiol-induced attenuation of hypoxic pulmonary vasoconstriction. | 1985 | Chest | pmid:3840073 |
Seitz M and Hunstein W | Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosus. | 1985 | Ann. Rheum. Dis. | pmid:4026405 |
Nomura S | [Plasma levels of thromboxane B2 and 6-keto PGF1 alpha in patients with variant angina]. | 1985 | Nippon Naika Gakkai Zasshi | pmid:3840191 |
Freund HR et al. | Muscle prostaglandin production in the rat. Effect of abdominal sepsis and different amino acid formulations. | 1985 | Arch Surg | pmid:4026556 |
Haurand M and Ullrich V | Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme. | 1985 | J. Biol. Chem. | pmid:2999104 |
Prosdocimi M et al. | Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery. | 1985 | Thromb. Res. | pmid:3840290 |
Lelcuk S et al. | Thromboxane A2 moderates permeability after limb ischemia. | 1985 | Ann. Surg. | pmid:3840349 |
Morris HG et al. | Effects of salsalate (nonacetylated salicylate) and aspirin on serum prostaglandins in humans. | 1985 | Ther Drug Monit | pmid:3866409 |
Wilson L and Huang LS | Contributions of the fetoplacental unit to augmented uterine prostaglandin levels periparturition in the rat. | 1985 | Biol. Reprod. | pmid:3840391 |
Chang J et al. | Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages. | 1985 | Eur. J. Pharmacol. | pmid:3920057 |
DiMinno G et al. | Increased binding of fibrinogen to platelets in diabetes: the role of prostaglandins and thromboxane. | 1985 | Blood | pmid:2981130 |
Shohami E and Gross J | An ex vivo method for evaluating prostaglandin synthetase activity in cortical slices of mouse brain. | 1985 | J. Neurochem. | pmid:3923156 |
De Caterina R et al. | Equal antiplatelet effects of aspirin 50 or 324 mg/day in patients after acute myocardial infarction. | 1985 | Thromb. Haemost. | pmid:4082090 |
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Semrad SD et al. | Flunixin meglumine given in small doses: pharmacokinetics and prostaglandin inhibition in healthy horses. | 1985 | Am. J. Vet. Res. | pmid:4083579 |
Ding YA et al. | Potentiation of adrenaline-induced platelet aggregation by angiotensin II. | 1985 | Thromb. Haemost. | pmid:4089801 |
Gay SW and Kosher RA | Prostaglandin synthesis during the course of limb cartilage differentiation in vitro. | 1985 | J Embryol Exp Morphol | pmid:3867724 |
Lawson JA et al. | Measurement of urinary 2,3-dinor-thromboxane B2 and thromboxane B2 using bonded-phase phenylboronic acid columns and capillary gas chromatography--negative-ion chemical ionization mass spectrometry. | 1985 | Anal. Biochem. | pmid:4091270 |
Reines HD et al. | Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock. | 1985 | Surg Gynecol Obstet | pmid:3983796 |
Alessandrini P et al. | Physiologic variables affecting thromboxane B2 production in human whole blood. | 1985 | Thromb. Res. | pmid:3983893 |
Fukushima M et al. | [Role of thromboxane A2 in pulmonary air embolism in conscious sheep]. | 1985 | Kokyu To Junkan | pmid:4023449 |
Conti P et al. | Effect of supernatants from PHA-stimulated and non-stimulated lymphocyte cultures on thromboxane B2 release by polymorphonuclear leukocytes in vitro. | 1985 | Agents Actions | pmid:4003201 |
Carter AJ and Hanley SP | The effect of platelet number and haematocrit on whole blood thromboxane synthesis. | 1985 | Thromb. Haemost. | pmid:4024033 |
Singer P et al. | Blood pressure- and lipid-lowering effect of mackerel and herring diet in patients with mild essential hypertension. | 1985 | Atherosclerosis | pmid:3000395 |