MeSH term | MeSH ID | Detail |
---|---|---|
Cholecystitis, Acute | D041881 | 1 associated lipids |
Gastric Dilatation | D013271 | 1 associated lipids |
Stomach Volvulus | D013277 | 1 associated lipids |
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Smith SR et al. | Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril. | 1993 | J. Am. Soc. Nephrol. | pmid:8305640 |
Nukina S et al. | Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells. | 1994 | Am. J. Physiol. | pmid:8304463 |
van Kooten F et al. | Evidence for episodic platelet activation in acute ischemic stroke. | 1994 | Stroke | pmid:8303731 |
Hofmann D et al. | Evidence for sustained platelet activation in patients with early postinfarction angina. | 1993 | Thromb. Res. | pmid:8303651 |
Salerno F et al. | Effects of imidazole-salicylate on renal function and the diuretic action of furosemide in cirrhotic patients with ascites. | 1993 | J. Hepatol. | pmid:8301062 |
Furuzono T et al. | A novel biomaterial: poly(dimethylsiloxane)-polyamide multiblock copolymer I. Synthesis and evaluation of blood compatibility. | 1993 | J Biomater Sci Polym Ed | pmid:8297834 |
Rabinovici R et al. | Interleukin-2-induced lung injury. The role of complement. | 1994 | Circ. Res. | pmid:8293571 |
Semrad SD et al. | Pharmacokinetics and effects of repeated administration of phenylbutazone in neonatal calves. | 1993 | Am. J. Vet. Res. | pmid:8291771 |
Semrad SD et al. | Effects of concurrent administration of phenylbutazone and flunixin meglumine on pharmacokinetic variables and in vitro generation of thromboxane B2 in mares. | 1993 | Am. J. Vet. Res. | pmid:8291770 |
Iioka H et al. | Studies on placental inhibition of platelet aggregation: a comparison of human syncytiotrophoblast brush border and basal plasma membranes. | 1993 Sep-Oct | Placenta | pmid:8290492 |
Textor SC et al. | Systemic and renal effects of nifedipine in cyclosporine-associated hypertension. | 1994 | Hypertension | pmid:8282363 |
Szczapa J et al. | [Effect of intraventricular hemorrhage in newborns on levels of certain prostanoids in blood plasma]. | 1993 | Ginekol. Pol. | pmid:8282238 |
Li Q et al. | Suppression of S-antigen-induced experimental autoimmune uveoretinitis in Lewis rats by oral administration with CGS-13080, a thromboxane synthetase inhibitor. | 1993 | Exp. Eye Res. | pmid:8282047 |
Mück AO et al. | The effect of 17 beta-estradiol and endothelin 1 on prostacyclin and thromboxane production in human endothelial cell cultures. | 1993 | Clin Exp Obstet Gynecol | pmid:8281701 |
Johnson BF et al. | Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids. | 1993 | Transplantation | pmid:8279018 |
Smith SR et al. | Chronic thromboxane synthase inhibition with CGS 12970 in human cyclosporine nephrotoxicity. | 1993 | Transplantation | pmid:8279014 |
Zhou W et al. | Lipid mediator production in acute and chronic pancreatitis in the rat. | 1994 | J. Surg. Res. | pmid:8277767 |
Heasman PA et al. | Flurbiprofen in the prevention and treatment of experimental gingivitis. | 1993 | J. Clin. Periodontol. | pmid:8276984 |
Uematsu T et al. | Changes in plasma and urinary 11-dehydrothromboxane B2 in healthy subjects produced by oral CS-518, a novel thromboxane synthase inhibitor. | 1993 | Eur. J. Clin. Pharmacol. | pmid:8276056 |
Lee M et al. | Dose effects of aspirin on gastric prostaglandins and stomach mucosal injury. | 1994 | Ann. Intern. Med. | pmid:8273981 |
Yavin E et al. | Gangliosides stimulate synthesis of prostaglandin E2 and prostacyclin in fetal rat brain hemispheres after episodes of global intrauterine ischemia. | 1993 | J. Neurosci. Res. | pmid:8271317 |
Wang S | [The effect of captopril on hemodynamics in patients of chronic obstructive pulmonary disease with pulmonary hypertension]. | 1993 | Zhonghua Nei Ke Za Zhi | pmid:8269786 |
Jin L et al. | [The effect of low dose aspirin on the platelet function in patients with acute myocardial infarction]. | 1993 | Zhonghua Nei Ke Za Zhi | pmid:8269785 |
King JN | The use of intradermal carrageenan in calves to estimate the dose of oxindanac, a nonsteroidal anti-inflammatory drug. | 1993 | Can. J. Vet. Res. | pmid:8269358 |
Fukuoka T et al. | Platelet-activating factor as a vasodepressive mediator of liver ischemia. | 1993 | Transplant. Proc. | pmid:8266523 |
Nakazawa I et al. | Some features in prostaglandin synthesis of the cancer cells which metastasized into liver from intestinal cancer lesions. | 1993 | Tohoku J. Exp. Med. | pmid:8266326 |
Yang B et al. | Dietary fish oil supplementation attenuates myocardial dysfunction and injury caused by global ischemia and reperfusion in isolated rat hearts. | 1993 | J. Nutr. | pmid:8263599 |
Chen G et al. | Prostacyclin, thromboxane and antioxidant levels in pregnancy-induced hypertension. | 1993 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:8262302 |
Zhang BL et al. | Effects of naftidrofuryl on isolated perfused kidneys of spontaneously hypertensive rats. | 1993 | Clin. Exp. Pharmacol. Physiol. | pmid:8261661 |
Falcon CR et al. | The in vitro production of thromboxane B2 by platelets of diabetic patients is normal at physiological concentrations of ionized calcium. | 1993 | Thromb. Haemost. | pmid:8259535 |
De Caterina R et al. | n-3 fatty acids reduce proteinuria in patients with chronic glomerular disease. | 1993 | Kidney Int. | pmid:8258959 |
Balteskard L et al. | Thromboxane production in the blood of women increases after menopause whereas tumor necrosis factor is reduced in women compared with men. | 1993 | Atherosclerosis | pmid:8257457 |
Reshetnikov O | Chronic gastritis, prostaglandins and Helicobacter pylori. | 1993 | Z Gastroenterol | pmid:8256482 |
Berger JI et al. | Effect of amrinone during group B Streptococcus-induced pulmonary hypertension in piglets. | 1993 | Pediatr. Pulmonol. | pmid:8255635 |
Williams B and Schrier RW | Glucose-induced protein kinase C activity regulates arachidonic acid release and eicosanoid production by cultured glomerular mesangial cells. | 1993 | J. Clin. Invest. | pmid:8254044 |
Fink MP et al. | A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model. | 1993 | Crit. Care Med. | pmid:8252886 |
Djurup R et al. | Rapid, direct enzyme immunoassay of 11-keto-thromboxane B2 in urine, validated by immunoaffinity/gas chromatography-mass spectrometry. | 1993 | Clin. Chem. | pmid:8252718 |
Jin YQ and Li XQ | [Pathophysiological basis of 3 subtypes in ganfeng neidong syndrome]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8251718 |
Huang TF et al. | Antiplatelet protease, kistomin, selectively cleaves human platelet glycoprotein Ib. | 1993 | Biochim. Biophys. Acta | pmid:8251530 |
Du ZY and Huang YH | Effects of tetrandrine on production of leukotriene B4 and thromboxane B2 in rabbit blood. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8249626 |
Matsuo Y et al. | Effect of a novel thromboxane A2 receptor antagonist, S-1452, on postischemic brain injury in rats. | 1993 | Stroke | pmid:8248988 |
Siler-Khodr TM and Forman J | Effect of IGF-1 on placental prostanoid production. | 1993 | Prostaglandins | pmid:8248549 |
Eskew ML et al. | Increased thromboxane A2 synthesis by rat lung neutrophils during selenium deficiency. | 1993 | Prostaglandins | pmid:8248545 |
Arruzazabala ML et al. | Effect of policosanol on cerebral ischemia in Mongolian gerbils: role of prostacyclin and thromboxane A2. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248276 |
Bell JG et al. | Dietary sunflower, linseed and fish oils affect phospholipid fatty acid composition, development of cardiac lesions, phospholipase activity and eicosanoid production in Atlantic salmon (Salmo salar). | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248271 |
Stengel PW et al. | Bronchopulmonary actions of 1-(1,2,3,4-tetrahydro-1-naphthylenyl)-1H-imidazole, nitric acid salt (LY150310), a substituted imidazole, in the guinea pig. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8246133 |
Zemel D et al. | Relationship of TNF-alpha, interleukin-6, and prostaglandins to peritoneal permeability for macromolecules during longitudinal follow-up of peritonitis in continuous ambulatory peritoneal dialysis. | 1993 | J. Lab. Clin. Med. | pmid:8245688 |
Zhou S et al. | [The changes in free radical and prostaglandin metabolism in newborn infants with asphyxia]. | 1993 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:8244309 |
Püschel GP et al. | Increase in prostanoid formation in rat liver macrophages (Kupffer cells) by human anaphylatoxin C3a. | 1993 | Hepatology | pmid:8244278 |
Myers SI et al. | Acute cholecystitis potentiates bradykinin stimulated fibroblast prostanoid release in the rabbit. | 1993 | Mol. Cell. Endocrinol. | pmid:8243803 |