| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cholecystitis, Acute | D041881 | 1 associated lipids |
| Gastric Dilatation | D013271 | 1 associated lipids |
| Stomach Volvulus | D013277 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jiang Z et al. | [The changes of thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 alpha(6-keto-PGF1 alpha) in the lungs of rats drowned in hypothermic-sea-water]. | 2002 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:14694611 |
| Kawata K et al. | The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury. | 2003 Nov-Dec | Hepatogastroenterology | pmid:14696445 |
| Ersöz G et al. | Effect of sodium selenite treatment on platelet aggregation of streptozotocin-induced diabetic rats. | 2003 | Thromb. Res. | pmid:14698654 |
| Al-Madaney MM et al. | Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity. | 2003 | Biochim. Biophys. Acta | pmid:14729070 |
| Wurtz MM et al. | Enhanced microvascular permeability of PMA-induced acute lung injury is not mediated by cyclooxygenase products. | 1992 | J. Appl. Physiol. | pmid:1474095 |
| Scott G et al. | Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects. | 2004 | J Clin Pharmacol | pmid:14747429 |
| Horiuchi H et al. | 1,25-Dihydroxyvitamin D3 inhibits thromboxane release from activated macrophages. | 1992 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:1475528 |
| Cotter G et al. | Lack of aspirin effect: aspirin resistance or resistance to taking aspirin? | 2004 | Am. Heart J. | pmid:14760328 |
| Horani MH et al. | Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2. | 2004 | Metab. Clin. Exp. | pmid:14767868 |
| Hayball PJ et al. | Enantioselective pharmacodynamics of the nonsteroidal antiinflammatory drug ketoprofen: in vitro inhibition of human platelet cyclooxygenase activity. | 1992 | Chirality | pmid:1476858 |
| Peck OM et al. | Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma. | 2004 | Shock | pmid:14770039 |
| Zhu PJ | [Therapeutic changes in nephrotic syndrome treated with yiqi huoxue jiedu decoction and corticosteroid]. | 1992 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:1477504 |
| Chetty N and Naran NH | Platelet hyperreactivity in hyperlipidaemia with specific reference to platelet lipids and fatty acid composition. | 1992 | Clin. Chim. Acta | pmid:1477981 |
| Ylikorkala O and Viinikka L | The role of prostaglandins in obstetrical disorders. | 1992 | Baillieres Clin Obstet Gynaecol | pmid:1477999 |
| Katoh K | Possible relevance of lipid peroxidation and thromboxane production to the initiation and/or evolution of microangiopathy in non-hyperlipidemic type 2 diabetes mellitus. | 1992 | Diabetes Res. Clin. Pract. | pmid:1478157 |
| Tóth L et al. | Elevated levels of plasma and urine beta-thromboglobulin or thromboxane-B2 as markers of real platelet hyperactivation in diabetic nephropathy. | 1992 | Haemostasis | pmid:1478544 |
| Truog WE et al. | Acute changes in vasoactive lipid mediators in experimental hyaline membrane disease. | 1992 | Respir Physiol | pmid:1480845 |
| Mozes T et al. | Lethal and non-lethal course of endotoxic shock is determined by interactions between tumor necrosis factor, platelet activating factor and eicosanoids. | 1992 | Pathol. Biol. | pmid:1484741 |
| Sochanowicz B and Dancewicz AM | Thromboxane increase in irradiated animals is caused by stimulation of cyclooxygenase activity. | 1992 | Acta Biochim. Pol. | pmid:1485488 |
| Desideri N et al. | Synthesis of some guanylhydrazones and imidazolinylhydrazones as thromboxane-synthase and platelet aggregation inhibitors. | 1992 | Arch. Pharm. (Weinheim) | pmid:1489254 |
| Ratzmann KP et al. | Improvement of metabolic control and changes of fatty acid composition do not alter platelet aggregability and thromboxane production in type 2 diabetes mellitus. | 1992 | Horm. Metab. Res. Suppl. | pmid:1490671 |
| Koch T et al. | Alterations of filtration coefficients in pulmonary edema of different pathogenesis. | 1992 | J. Appl. Physiol. | pmid:1490949 |
| Longworth KE et al. | Development of pulmonary intravascular macrophage function in newborn lambs. | 1992 | J. Appl. Physiol. | pmid:1490977 |
| Abbakumov VV et al. | [The prostacyclin-thromboxane system and platelet hemostasis following aortocoronary bypass with an uncomplicated postoperative course]. | 1992 Sep-Dec | Anesteziol Reanimatol | pmid:1492691 |
| Nakayama DK et al. | Relation between arterial hypoxemia and plasma eicosanoids in neonates with congenital diaphragmatic hernia. | 1992 | J. Surg. Res. | pmid:1494296 |
| Bruno A et al. | Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. | 2004 | Stroke | pmid:14963281 |
| Kwak SH et al. | Effects of propofol on endotoxin-induced acute lung injury in rabbit. | 2004 | J. Korean Med. Sci. | pmid:14966342 |
| Urade M et al. | Changes of thromboxane B2 level in experimental orthotopic liver transplantation in swines--the effect of warm ischemia and thromboxane A2 synthetase inhibition. | 1992 | Transplant. Proc. | pmid:1496677 |
| Noris M et al. | Renal prostacyclin biosynthesis is reduced in children with hemolytic-uremic syndrome in the context of systemic platelet activation. | 1992 | Am. J. Kidney Dis. | pmid:1496967 |
| Swaim SF et al. | Evaluation of the dermal effects of cast padding in coaptation casts on dogs. | 1992 | Am. J. Vet. Res. | pmid:1497201 |
| Tsai CY et al. | Proinflammatory cytokines enhance COX-1 gene expression in cultured rat glomerular mesangial cells. | 2004 | Int. Immunopharmacol. | pmid:14975359 |
| Smalling WE et al. | Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets. | 2004 | Biol. Neonate | pmid:14981352 |
| Kawada N et al. | Possible induction of fatty acid cyclo-oxygenase in lipopolysaccharide-stimulated rat Kupffer cells. | 1992 | Gastroenterology | pmid:1499903 |
| Yugar-Toledo JC et al. | Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction. | 2004 | Chest | pmid:15006938 |
| Takashima M et al. | [A trial of low-dose aspirin therapy in high-risk pregnancy]. | 1992 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:1500806 |
| DÃaz AM et al. | Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity. | 2004 | Life Sci. | pmid:15010262 |
| Li D et al. | Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. | 2003 | Biomed. Environ. Sci. | pmid:15011964 |
| Ikonomidis I et al. | Reduction of daily life ischaemia by aspirin in patients with angina: underlying link between thromboxane A2 and macrophage colony stimulating factor. | 2004 | Heart | pmid:15020512 |
| Lassila R and Laustiola KE | Cigarette smoking and platelet-vessel wall interactions. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1502254 |
| Uehara Y et al. | Abnormal response of urinary eicosanoid system to norepinephrine infusion in patients with essential hypertension. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1502257 |
| Dippel DW et al. | What is the lowest dose of aspirin for maximum suppression of in vivo thromboxane production after a transient ischemic attack or ischemic stroke? | 2004 | Cerebrovasc. Dis. | pmid:15026612 |
| Capone ML et al. | Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. | 2004 | Circulation | pmid:15037526 |
| Jones SB et al. | Altered aortic production of 6-keto-prostaglandin F1 alpha from aldosterone-salt hypertensive rats. | 1992 May-Jun | J. Vasc. Res. | pmid:1504198 |
| Rotondo S et al. | Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation. | 2004 | Eur. J. Pharmacol. | pmid:15044038 |
| Guay J et al. | Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1. | 2004 | J. Biol. Chem. | pmid:15044444 |
| Véricel E et al. | Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status. | 2004 | Diabetes | pmid:15047620 |
| Dinev D and Andonova M | The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. | 2004 | Vet Anaesth Analg | pmid:15053753 |
| Wang YY et al. | Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. | 2004 | Acta Pharmacol. Sin. | pmid:15066215 |
| Yoshimura T et al. | [Urinary 11-dehydrothromboxane B2 and 6-keto-prostaglandin F1 alpha in normal pregnant women and in women complicated with pregnancy-induced hypertension]. | 1992 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:1506726 |
| Park HS et al. | Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. | 2004 | J. Nutr. Biochem. | pmid:15068816 |
| Zhang C et al. | Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. | 2004 | J. Cardiovasc. Pharmacol. | pmid:15071353 |
| Brunkwall JS et al. | Papaverine effects on PGI2 and TXA2 release from the canine vascular wall. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1508951 |
| Arnold JH et al. | Production of platelet thromboxane A2 and arterial prostacyclin I2 from hypercholesterolemic rats. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1508954 |
| Evangelista V et al. | Defibrotide inhibits platelet activation by cathepsin G released from stimulated polymorphonuclear leukocytes. | 1992 | Thromb. Haemost. | pmid:1509406 |
| Ishitsuka Y et al. | Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. | 2004 | J. Pharm. Pharmacol. | pmid:15099446 |
| Leonhardt A et al. | Reference intervals and developmental changes in urinary prostanoid excretion in healthy newborns, infants and children. | 1992 | Acta Paediatr. | pmid:1511190 |
| Caprani A et al. | Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure. | 2004 | Bioelectromagnetics | pmid:15114641 |
| Rabinovici R et al. | Biological responses to exchange transfusion with liposome-encapsulated hemoglobin. | 1992 | Circ. Shock | pmid:1511503 |
| Di Minno G and Violi F | Aspirin resistance and diabetic angiopathy: back to the future. | 2004 | Thromb. Res. | pmid:15115664 |
| Torsney E et al. | Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. | 2004 | Circ. Res. | pmid:15117816 |
| Ghuysen A et al. | Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. | 2004 | J. Pharmacol. Exp. Ther. | pmid:15121765 |
| Akbiyik F et al. | Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. | 2004 | Blood | pmid:15130939 |
| Menzies-Gow NJ et al. | Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. | 2004 | Equine Vet. J. | pmid:15147137 |
| Hammer C et al. | Bridging to transplant: allogeneic heart transplantation after xenografting. | 1992 Jul-Aug | J. Heart Lung Transplant. | pmid:1515437 |
| Orosz L et al. | Blood glucose and diabetic retinopathy. | 1992 | BMJ | pmid:1515807 |
| Gross GJ and Moore J | Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. | 2004 | Pharmacology | pmid:15161995 |
| Suzuki N et al. | Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165035 |
| Nejad HH and Bottje WG | Glutathione depletion and rabbit renal medulla 6-ketoPGF1 alpha and TxB2: levels in vivo and following homogenate incubation in vitro. | 1992 | Int. J. Biochem. | pmid:1516728 |
| Korkushko OV et al. | [Some mechanisms of the development of endothelial disfunction in aging]. | 2004 | Fiziol Zh | pmid:15174205 |
| Kawano T et al. | Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. | 2004 | Int. Arch. Allergy Immunol. | pmid:15178893 |
| Barbara J et al. | Inhaled cornstarch glove powder increases latex-induced airway hyper-sensitivity in guinea-pigs. | 2004 | Clin. Exp. Allergy | pmid:15196289 |
| Wu KJ et al. | [Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome]. | 2004 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:15196341 |
| Riutta A et al. | Solid-phase extraction of urinary 11-dehydrothromboxane B2 for reliable determination with radioimmunoassay. | 1992 | Anal. Biochem. | pmid:1519756 |
| Van Ryn J et al. | Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. | 2004 | J Clin Pharmacol | pmid:15199082 |
| Imai T et al. | [Role of thromboxane A2 and prostaglandin I2 in the increase of airway responsiveness in dogs after ozone exposure]. | 1992 | Arerugi | pmid:1520068 |
| Aikawa K et al. | Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs. | 2004 | Coron. Artery Dis. | pmid:15201617 |
| Barbieri SS et al. | Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. | 2004 | Free Radic. Biol. Med. | pmid:15203187 |
| Goerig M et al. | A new role for nicotine: selective inhibition of thromboxane formation by direct interaction with thromboxane synthase in human promyelocytic leukaemia cells differentiating into macrophages. | 1992 Mar-Apr | Clin Investig | pmid:1521038 |
| Kawada N et al. | TP receptors regulate renal hemodynamics during angiotensin II slow pressor response. | 2004 | Am. J. Physiol. Renal Physiol. | pmid:15213069 |
| Matsumoto Y et al. | Effects of Y-20811, a thromboxane A2 synthetase inhibitor, on experimentally induced coronary thrombosis in anesthetized dogs. | 1992 | Eur. J. Pharmacol. | pmid:1521557 |
| Lorenzoni R et al. | Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. | 2004 | Am. Heart J. | pmid:15215815 |
| Levin JH et al. | Estradiol stimulates the secretion of prostacyclin and thromboxane from endometrial stromal cells in culture. | 1992 | Fertil. Steril. | pmid:1521648 |
| Harizi H et al. | Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells. | 2004 | Cell. Immunol. | pmid:15219461 |
| Meagher LC et al. | Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2. | 1992 | J. Leukoc. Biol. | pmid:1522386 |
| Gu L et al. | [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. | 2003 | Zhongguo Zhong Yao Za Zhi | pmid:15224660 |
| Kojima F et al. | Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. | 2004 | Arthritis Res. Ther. | pmid:15225371 |
| Farndale RW et al. | Measurement of platelet arachidonic acid metabolism. | 2004 | Methods Mol. Biol. | pmid:15226540 |
| Radvanyi-Hofmann H et al. | Characterization of a thrombopathy (type delta storage pool disease) affecting a pig colony. | 1992 | Nouv Rev Fr Hematol | pmid:1523094 |
| Teng CM et al. | Antiplatelet actions of some coumarin compounds isolated from plant sources. | 1992 | Thromb. Res. | pmid:1523611 |
| Singer P and Wirth M | Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15253884 |
| Barrière G et al. | PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells. | 2004 May-Jun | Anticancer Res. | pmid:15274299 |
| Valeri CR et al. | In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells. | 2004 | J Trauma | pmid:15280746 |
| Heering P et al. | The role of thromboxane and prostacyclin in ciclosporin-induced nephrotoxicity. | 1992 | Nephron | pmid:1528337 |
| Sheu JR et al. | Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. | 2004 | Br. J. Pharmacol. | pmid:15289295 |
| Toth B et al. | Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. | 2004 | J. Appl. Physiol. | pmid:15298985 |
| Byrick RJ et al. | Ibuprofen pretreatment does not prevent hemodynamic instability after cemented arthroplasty in dogs. | 1992 | Anesth. Analg. | pmid:1530164 |
| Ferroni P et al. | Platelet activation in type 2 diabetes mellitus. | 2004 | J. Thromb. Haemost. | pmid:15304032 |
| Visioli F et al. | Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. | 2005 | Eur J Nutr | pmid:15309433 |
| MacDermot J et al. | The identity of IgE receptors (Fc epsilon RII) that mediate cellular activation of human macrophages: evidence against a role for CD23. | 1992 | Mol. Immunol. | pmid:1530985 |
| Craft JA et al. | Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. | 2004 | Blood Coagul. Fibrinolysis | pmid:15311156 |