Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Cholecystitis, Acute D041881 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Mitchell MD et al. Thromboxane B-2 in the plasma and amniotic fluid of late pregnant and periparturient sheep. 1979 J. Reprod. Fertil. pmid:423152
Tobelem G et al. Further studies on a specific platelet antibody found in Bernard-Soulier syndrome and its effects on normal platelet function. 1979 Br. J. Haematol. pmid:427045
Lefer AM et al. Protective effects of a novel thromboxane analog in lethal traumatic shock. 1979 Prostaglandins Med pmid:552102
Lewy RI et al. Comparison of plasma concentrations of thromboxane B2 in Prinzmetal's variant angina and classical angina pectoris. 1979 Clin Cardiol pmid:544110
Best LC et al. Evidence that extracellular calcium ions inhibit thromboxane B2 biosynthesis by human platelets. 1979 Biochem. Biophys. Res. Commun. pmid:117802
Oelz O [The arachidonic acid metabolites (prostaglandins, thromboxanes, prostacyclin, leucotrienes):basics and clinical implications (author's transl)]. 1979 Ther Umsch pmid:119331
Robak J and Kasperczyk H [Prostaglandin synthetase components (author's transl)]. 1979 Postepy Biochem. pmid:120943
Tremoli E et al. Platelet thromboxanes and serum-cholesterol. 1979 Lancet pmid:84115
Makheia AN et al. Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. 1979 Lancet pmid:86023
Lewy RI et al. Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. 1979 Lancet pmid:87990
Güllner HG et al. Prostacyclin overproduction in Bartter's syndrome. 1979 Lancet pmid:90861
Davis TM et al. Prostacyclin and thromboxane metabolites in diabetes. 1979 Lancet pmid:90875
Best L et al. Effect of glucose on platelet thromboxane biosynthesis. 1979 Lancet pmid:90876
Gorman RR et al. Independence of the cyclic AMP-lowering activity of thromboxane A2 from the platelet release reaction. 1979 Biochim. Biophys. Acta pmid:216409
Fitzpatrick FA and Gorman RR Regulatory role of cyclic adenosine 3',5'-monophosphate on the platelet cyclooxygenase and platelet function. 1979 Biochim. Biophys. Acta pmid:216415
Best LC et al. Mode of action of dipyridamole on human platelets. 1979 Thromb. Res. pmid:229583
Marcus AJ The role of prostaglandins in platelet function. 1979 Prog Hematol pmid:230534
Spagnuolo C et al. PGF2 alpha, thromboxane B2 and HETE levels in gerbil brain cortex after ligation of common carotid arteries and decapitation. 1979 Prostaglandins pmid:230539
Jonsson CE et al. Efflux of cyclic AMP, prostaglandin E2 and F2 alpha and thromboxane B2 in leg lymph of rabbits after scalding injury. 1979 Acta Physiol. Scand. pmid:232367
Karmazyn M and Dhalla NS Thromboxane B2: a cardiodepressant of isolated rat hearts and inhibitor of sarcolemma Na+ - K+ stimulated ATPase activity. 1979 Prostaglandins Med pmid:233217