Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Cholecystitis, Acute D041881 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Cuiper LL et al. Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2. 1996 J. Appl. Physiol. pmid:8847301
Nowak J et al. Thromboxane metabolite excretion in patients with hand-arm vibration syndrome. 1996 Clin Physiol pmid:8842572
Stichtenoth DO et al. Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. 1995 Nov-Dec Prostaglandins pmid:8838242
Muller M and Sorrell TC Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. 1995 Nov-Dec Prostaglandins pmid:8838240
Fylling AC et al. Kinetic and structural evidence for the identification of 11-hydroxythromboxane B2 dehydrogenase as cytosolic aldehyde dehydrogenase. 1995 Nov-Dec Prostaglandins pmid:8838239
Meade CJ et al. Pulmonary pharmacology of DT-TX 30 SE, a potent selective combined thromboxane synthetase inhibitor and receptor antagonist, in guinea pigs. 1996 Jpn. J. Pharmacol. pmid:8835638
Osiovich H et al. Cardiopulmonary effects of tumor necrosis factor-alpha in the piglet: influence of cyclooxygenase inhibition. 1995 Biol. Neonate pmid:8835089
Myers SI et al. Long-term resuscitation of hemorrhage/reperfusion injury (H/R) stimulates renal PGE2 release. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8832762
Mizugaki M et al. Microdetermination of 11-dehydrothromboxane B3 in human urine by gas chromatography--selected-ion monitoring using (18O2) analogue as an internal standard. 1995 Rapid Commun. Mass Spectrom. pmid:8829485
Ishibashi M et al. Identification of 11-dehydro-2,3-dinorthromboxane B3 in human urine based on the mass spectral properties of 11-dehydrothromboxane B3 and related compounds. 1995 Rapid Commun. Mass Spectrom. pmid:8829476
Mitten LA et al. Phenylbutazone increases right atrial pressure and heart rate of running horses. 1996 J. Appl. Physiol. pmid:8828679
Watanabe M et al. [Changes in platelet sensitivity to thromboxane A2 in pediatric patients with nephrotic syndrome]. 1996 Nihon Jinzo Gakkai Shi pmid:8828355
Meenan J et al. Lexipafant (BB-882), a platelet activating factor receptor antagonist, ameliorates mucosal inflammation in an animal model of colitis. 1996 Eur J Gastroenterol Hepatol pmid:8823572
Wagner RS et al. Activation of thromboxane A2 receptors alters lipopolysaccharide-induced adherence of THP-1 cells. 1996 Shock pmid:8821102
Davì G et al. Influence of metabolic control on thromboxane biosynthesis and plasma plasminogen activator inhibitor type-1 in non-insulin-dependent diabetes mellitus. 1996 Thromb. Haemost. pmid:8819248
Galbraith EA and McKellar QA Protein binding and in vitro serum thromboxane B2 inhibition by flunixin meglumine and meclofenamic acid in dog, goat and horse blood. 1996 Res. Vet. Sci. pmid:8819199
Landoni MF et al. Pharmacokinetics and pharmacodynamics of tolfenamic acid in calves. 1996 Res. Vet. Sci. pmid:8819190
Yoshida SH et al. Dietary Juniperis virginiensis seed oil decreased pentobarbital-associated mortalities among DBA/1 mice treated with collagen-adjuvant emulsions. 1996 J Lipid Mediat Cell Signal pmid:8816989
Pace-Asciak CR et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. 1996 Clin. Chim. Acta pmid:8814965
Zhen ZY et al. Experimental study on microthrombi and myocardial injuries. 1996 Microvasc. Res. pmid:8812763
Giulian D et al. Activated microglia are the principal glial source of thromboxane in the central nervous system. 1996 Neurochem. Int. pmid:8808790
González ET et al. Prostanoid modulation of glucose transport in isolated diabetic rat uterus. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8804128
Feng J et al. Beneficial effects of iloprost cardioplegia in ischemic arrest in isolated working rat heart. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8804125
Fekkes D et al. Eicosanoid and amino acid metabolism in transient acute psychoses with psychedelic symptoms. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8804122
Lewy RI et al. Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. 1979 Lancet pmid:87990
Morrow JD et al. Nonenzymatic free radical-catalyzed generation of thromboxane-like compounds (isothromboxanes) in vivo. 1996 J. Biol. Chem. pmid:8798513
Fox GA et al. Cyclooxygenase inhibition and vascular reactivity in a rat model of hyperdynamic sepsis. 1996 J. Cardiovasc. Pharmacol. pmid:8797133
Sakurai S et al. Synthesis of [[(benzenesulfonamido)alkyl]phenyl]alkanoic acid derivatives containing pyridyl or imidazolyl groups and their thromboxane A2 receptor antagonistic and thromboxane A2 synthase inhibitory activities. 1996 Chem. Pharm. Bull. pmid:8795270
Ko FN et al. Mechanism of action of p-chlorobiphenyl on the inhibition of platelet aggregation. 1996 J. Pharm. Pharmacol. pmid:8794990
Uematsu T et al. Pharmacokinetic and pharmacodynamic properties of FK070 (KDI-792), a novel thromboxane receptor antagonist/thromboxane synthetase inhibitor, after single and multiple oral administrations to healthy volunteers. 1996 J. Pharm. Pharmacol. pmid:8794987
Eriksson M et al. Beneficial effects of pre-treatment with vitamin A on cardiac and pulmonary functions in endotoxaemic pigs. 1996 Acta Anaesthesiol Scand pmid:8792882
Collins CE et al. Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. 1996 Aliment. Pharmacol. Ther. pmid:8791957
Aïssa J et al. Biochemical and cellular effects of heparin-protamine injection in rabbits are partially inhibited by a PAF-acether receptor antagonist. 1996 Eur. J. Pharmacol. pmid:8791000
Vaskonen T et al. Interrelationships between salt and fish oil in stroke-prone spontaneously hypertensive rat. 1996 Blood Press. pmid:8790929
Raptopoulos D et al. The effect of xylazine on plasma thromboxane B2 concentration in sheep. 1995 J. Vet. Pharmacol. Ther. pmid:8789696
Bell SJ et al. Dietary fish oil and cytokine and eicosanoid production during human immunodeficiency virus infection. 1996 Jan-Feb JPEN J Parenter Enteral Nutr pmid:8788262
Zheng NX et al. Pharmacokinetic and pharmacodynamic studies of a thromboxane synthetase inhibitor, ozagrel, in rabbits. 1995 Biol. Pharm. Bull. pmid:8787798
Cuzzolin L et al. Effect of single and repeated doses of a new nitroderivative of acetylsalicylic acid on platelet TXA2 production in rats. 1996 Life Sci. pmid:8786689
Uhlig S et al. Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin. 1996 Mol. Med. pmid:8784790
Gennaro M et al. Perfluorocarbon emulsion prevents eicoasanoid release in skeletal muscle ischemia and reperfusion. 1996 Cardiovasc Surg pmid:8782946
Nabe T et al. Sephadex G-200-induced eosinophil infiltration into airways in non-sensitized and sensitized guinea pigs, and responsiveness of the cells to stimuli in vitro. 1996 Jpn. J. Pharmacol. pmid:8774762
Quoc KP and Pascaud M Effects of dietary gamma-linolenic acid on the tissue phospholipid fatty acid composition and the synthesis of eicosanoids in rats. 1996 Ann. Nutr. Metab. pmid:8773734
Madan ZM and Sainani GS Effect of aspirin treatment on plasma levels of keto PGF 1 alpha and thromboxane B2. 1995 J Assoc Physicians India pmid:8773058
Mehta PJ et al. More uses of known drugs. 1995 J Assoc Physicians India pmid:8773057
Closa D et al. Hepatic involvement in pancreatitis-induced lung damage. 1996 Am. J. Physiol. pmid:8772495
Abernathy VJ et al. C-reactive protein inhibits increased pulmonary vascular permeability induced by fMLP in isolated rabbit lungs. 1996 Am. J. Physiol. pmid:8770090
Shirabe K et al. Inhibition of thromboxane A2 activity during warm ischemia of the liver. 1996 J. Surg. Res. pmid:8769950
Qiu BS et al. Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats. 1996 Dig. Dis. Sci. pmid:8769290
Hrboticky N et al. Linoleic acid esterified in low density lipoprotein serves as substrate for increased arachidonic acid synthesis in differentiating monocytic cells. 1996 Biochim. Biophys. Acta pmid:8765140
Fleisch JH et al. Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel secretory phospholipase A2 inhibitor. 1996 J. Pharmacol. Exp. Ther. pmid:8764358