Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Contusions D003288 3 associated lipids
Macular Edema D008269 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Yang Deficiency D016711 3 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Jejunal Diseases D007579 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Kumlin M et al. Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics. 1992 Am. Rev. Respir. Dis. pmid:1320824
Winther K et al. Platelet function and fibrinolytic activity in cervical spinal cord injured patients. 1992 Thromb. Res. pmid:1321515
Mantelli L et al. Effects of thromboxane agonists on cardiac adrenergic neurotransmission. 1992 Eur. J. Pharmacol. pmid:1323473
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Conroy DM et al. Vasoactive intestinal peptide and helodermin inhibit the release of cyclo-oxygenase products induced by leukotriene D4 and bradykinin from guinea-pig perfused lung. 1992 Eur. J. Pharmacol. pmid:1327827
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Juergens UR et al. Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge. 1992 J. Allergy Clin. Immunol. pmid:1328344
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Omura Y et al. Common factors contributing to intractable pain and medical problems with insufficient drug uptake in areas to be treated, and their pathogenesis and treatment: Part I. Combined use of medication with acupuncture, (+) Qi gong energy-stored material, soft laser or electrical stimulation. 1992 Acupunct Electrother Res pmid:1353650
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Amsterdam EA et al. Contractile actions of C5a on isolated porcine myocardium. 1992 Am. J. Physiol. pmid:1357981
Lee TK et al. Dissociation of inhibitory effects of low-dose ASA on thromboxane production and platelet aggregation in ischemic stroke patients. 1992 J. Formos. Med. Assoc. pmid:1363390
Tang Z [Effect of moxibustion on humoral factors in the rat infected with epidemic hemorrhagic fever virus]. 1992 Zhen Ci Yan Jiu pmid:1364109
Dai H et al. Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty. 2003 Postgrad Med J pmid:13679549
Traber LD et al. Pentafraction reduces the lung lymph response after endotoxin administration in the ovine model. 1992 Circ. Shock pmid:1374688
Squadrito F et al. Protective effects of G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock. 1992 J. Cardiovasc. Pharmacol. pmid:1375677
Terres W et al. Residual platelet function under acetylsalicylic acid and the risk of restenosis after coronary angioplasty. 1992 J. Cardiovasc. Pharmacol. pmid:1376787
Berti F et al. Protective activity of inhaled frusemide against immunological respiratory changes and mediator release in guinea-pigs. 1992 Pulm Pharmacol pmid:1377065
Elias M et al. Stabilization of standard platelet concentrates and minimization of the platelet storage lesion by a prostacyclin analogue. 1992 Ann. Hematol. pmid:1379080
Pretolani M et al. Effect of human recombinant interleukin-5 on in vitro responsiveness to PAF of lung from actively sensitized guinea-pigs. 1992 Br. J. Pharmacol. pmid:1380388
Havel MP et al. Aprotinin decreases release of 6-keto-prostaglandin F1 alpha and increases release of thromboxane B2 in cultured human umbilical vein endothelial cells. 1992 J. Thorac. Cardiovasc. Surg. pmid:1381028
Wu G et al. Inhibition effects of KRDS, a peptide derived from lactotransferrin, on platelet function and arterial thrombus formation in dogs. 1992 Haemostasis pmid:1381697
Laffi G et al. Thromboxane-receptor blockade increases water diuresis in cirrhotic patients with ascites. 1992 Gastroenterology pmid:1386823
Wilkes BM et al. Reduced glomerular thromboxane receptor sites and vasoconstrictor responses in diabetic rats. 1992 Kidney Int. pmid:1387436
Douma S et al. Effects of adrenaline infusion on serum thromboxane B2 and plasma beta-thromboglobulin levels in hypertensive and normotensive subjects. 1992 Nouv Rev Fr Hematol pmid:1387933
Grauer GF et al. Effects of a thromboxane synthetase inhibitor on established immune complex glomerulonephritis in dogs. 1992 Am. J. Vet. Res. pmid:1388004
Lei ZM et al. Expression of thromboxane A2 receptor gene and thromboxane A2 synthase in bovine corpora lutea. 1992 Biol. Reprod. pmid:1391329
Burhop KE et al. Effects of intravenous infusions of diaspirin cross-linked hemoglobin (DCLHb) on sheep. 1992 Biomater Artif Cells Immobilization Biotechnol pmid:1391481
Uyama O et al. Urinary 11-dehydro-thromboxane B2: a quantitative index of platelet activation in cerebral infarction. 1992 Intern. Med. pmid:1392173
Takeda H et al. Abnormalities in platelets and vascular endothelial cells induced by glycated lipoproteins. 1992 Intern. Med. pmid:1392175
Ding Q [Clinical study of qianxining in the treatment of 60 cases of yang hyperactivity due to yin deficiency type of hypertension]. 1992 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:1392491
Zhou Q [Experimental study of atherosclerosis and cholelithiasis with the same treatment. I. Effects of yiqi huoxue and shugan liqi agents in atherosclerosis of rabbit]. 1992 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:1392494