Patel YM et al. |
Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder. |
2003 |
Blood |
pmid:12609843
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Hausman N et al. |
Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit. |
2003 |
Prostaglandins Other Lipid Mediat. |
pmid:12611495
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Basta M et al. |
F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. |
2003 |
Nat. Med. |
pmid:12612546
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Fiorucci S et al. |
Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study. |
2003 |
Gastroenterology |
pmid:12612897
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Vigorita MG et al. |
Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. |
2003 |
Bioorg. Med. Chem. |
pmid:12614885
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Vass G et al. |
Comparison of nasal and oral inhalation during exhaled breath condensate collection. |
2003 |
Am. J. Respir. Crit. Care Med. |
pmid:12493648
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Gama de Abreu M et al. |
One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model. |
2003 |
Anesth. Analg. |
pmid:12505956
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Szebeni J et al. |
Complement activation during hemorrhagic shock and resuscitation in swine. |
2003 |
Shock |
pmid:14501949
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Vani G et al. |
Histone H1 modulates immune status in experimental breast cancer. |
2003 |
Chemotherapy |
pmid:14504437
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Xia Z et al. |
Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. |
2003 |
J. Thorac. Cardiovasc. Surg. |
pmid:14666012
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Ziser A et al. |
Propofol does not induce pulmonary dysfunction in stressed endotoxic pigs receiving Intralipid. |
2003 |
Crit. Care Med. |
pmid:12847400
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Chen Z et al. |
[Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis]. |
2003 |
Zhong Xi Yi Jie He Xue Bao |
pmid:15339561
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He LQ et al. |
[Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy]. |
2003 |
Zhong Xi Yi Jie He Xue Bao |
pmid:15339583
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Sheu JR et al. |
Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments. |
2003 |
Exp. Biol. Med. (Maywood) |
pmid:14681547
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Fike CD et al. |
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12388340
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Li D et al. |
Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. |
2003 |
Biomed. Environ. Sci. |
pmid:15011964
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Dionne RA et al. |
Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation. |
2003 |
J. Oral Maxillofac. Surg. |
pmid:12966473
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Tsipas G and Morphake P |
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. |
2003 |
J. Nutr. Biochem. |
pmid:12948879
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Cerletti C et al. |
Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. |
2003 |
Clin Pharmacokinet |
pmid:12959636
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Dai H et al. |
Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty. |
2003 |
Postgrad Med J |
pmid:13679549
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Liu H et al. |
Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:12973949
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Hart RG et al. |
Aspirin dosage and thromboxane synthesis in patients with vascular disease. |
2003 |
Pharmacotherapy |
pmid:12741431
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Pfeiffer S et al. |
Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. |
2003 |
Transplantation |
pmid:12698079
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Arifah AK et al. |
Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. |
2003 |
J. Vet. Pharmacol. Ther. |
pmid:12667184
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Davì G et al. |
Platelet activation in obese women: role of inflammation and oxidant stress. |
2002 Oct 23-30 |
JAMA |
pmid:12387653
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Hayashi M et al. |
Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. |
2002 Nov-Dec |
Eur. J. Haematol. |
pmid:12460234
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Wolfram RM et al. |
Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers. |
2002 May-Jun |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12144875
|
Alarayyed NA et al. |
Differential actions of naftopidil, doxazosin and nifedipine on platelet thromboxane generation and platelet-derived growth factor efflux in vitro. |
2002 Aug-Sep |
Platelets |
pmid:12189011
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Ersöz G et al. |
Effect of submaximal and incremental upper extremity exercise on platelet function and the role of blood shear stress. |
2002 |
Thromb. Res. |
pmid:12676189
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Connolly E et al. |
Cyclooxygenase isozyme expression and intimal hyperplasia in a rat model of balloon angioplasty. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:11805196
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Pinheiro RM and Calixto JB |
Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation. |
2002 |
Inflamm. Res. |
pmid:12558194
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Saldeen P et al. |
Signs of platelet activation, but not lipid peroxidation, in fetal blood associated with functional and structural umbilicoplacental lesions in pregnancies complicated by impaired glucose metabolism. |
2002 |
J. Matern. Fetal. Neonatal. Med. |
pmid:12530613
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Bermejo BP et al. |
Sesquiterpenes from Jasonia glutinosa: in vitro anti-inflammatory activity. |
2002 |
Biol. Pharm. Bull. |
pmid:11824534
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Ersöz G et al. |
The effect of submaximal exercise on platelet aggregation during late follicular and midluteal phases in women. |
2002 |
Thromb. Res. |
pmid:12590951
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Küsters S et al. |
Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells. |
2002 |
Arzneimittelforschung |
pmid:11878205
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Lassus P et al. |
Pulmonary prostacyclin is associated with less severe respiratory distress in preterm infants. |
2002 |
Early Hum. Dev. |
pmid:11893431
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Venuto R et al. |
Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11893597
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Wainwright CL et al. |
NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs. |
2002 |
Br. J. Pharmacol. |
pmid:11959790
|
Sheu JR et al. |
Mechanisms involved in the antiplatelet activity of midazolam in human platelets. |
2002 |
Anesthesiology |
pmid:11873041
|
Horiguchi T et al. |
Study on the usefulness of seratrodast in the treatment of chronic pulmonary emphysema. |
2002 |
Arzneimittelforschung |
pmid:12442639
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Zaitsu M et al. |
Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12468261
|
Thomson M et al. |
The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12468270
|
Sheu JR et al. |
Mechanisms involved in the antiplatelet activity of magnesium in human platelets. |
2002 |
Br. J. Haematol. |
pmid:12472585
|
Fiorucci S et al. |
NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide. |
2002 |
Circulation |
pmid:12473561
|
Rouvier J et al. |
Aspirin resistance. |
2002 |
Circulation |
pmid:12473569
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Celik I et al. |
Effects of ibuprofen on the physiology and outcome of rabbit endotoxic shock. |
2002 |
BMC Infect. Dis. |
pmid:12445332
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Dai CF et al. |
[Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis]. |
2002 |
Zhonghua Nan Ke Xue |
pmid:12479132
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Khan I et al. |
Cyclooxygenase-2 inhibition and experimental colitis: beneficial effects of phosphorothioated antisense oligonucleotide and meloxicam. |
2002 |
Scand. J. Gastroenterol. |
pmid:12523593
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Miyataka M et al. |
Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2. |
2002 |
Hypertension |
pmid:11897764
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Minuz P et al. |
Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. |
2002 |
Circulation |
pmid:12451006
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Leahy KM et al. |
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. |
2002 |
Cancer Res. |
pmid:11830509
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Ozaki N et al. |
Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits. |
2002 |
Prostaglandins Other Lipid Mediat. |
pmid:12428679
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Ma LP et al. |
Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia. |
2002 |
J Assoc Acad Minor Phys |
pmid:11852667
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Ochi T and Goto T |
Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis. |
2002 |
Br. J. Pharmacol. |
pmid:11834626
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De La Cruz JP et al. |
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction. |
2002 |
Br. J. Pharmacol. |
pmid:12429581
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Canbaz M et al. |
Effects of tibolone on thromboxane B(2) levels in postmenopausal women. |
2002 |
Gynecol. Obstet. Invest. |
pmid:11803222
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Huang F et al. |
Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats. |
2002 |
J. Cardiovasc. Pharmacol. |
pmid:11791012
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Bayorh MA et al. |
1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats. |
2002 |
Peptides |
pmid:11814618
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Streppa HK et al. |
Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood. |
2002 |
Am. J. Vet. Res. |
pmid:16206787
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Jiang Z et al. |
[The changes of thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 alpha(6-keto-PGF1 alpha) in the lungs of rats drowned in hypothermic-sea-water]. |
2002 |
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi |
pmid:14694611
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Saareks V et al. |
Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. |
2002 |
Pharmacol. Toxicol. |
pmid:12403056
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Kudolo GB et al. |
Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. |
2002 |
Thromb. Res. |
pmid:12590952
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Sinzinger H |
Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications". |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12445490
|
Obase Y et al. |
Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. |
2002 |
Chest |
pmid:11796443
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Gordon SM et al. |
Peripheral prostanoid levels and nonsteroidal anti-inflammatory drug analgesia: replicate clinical trials in a tissue injury model. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12189364
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Van Hecken A et al. |
Effects of enteric-coated, low-dose aspirin on parameters of platelet function. |
2002 |
Aliment. Pharmacol. Ther. |
pmid:12197849
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Gómez-Gaviro MV et al. |
Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs. |
2002 |
J. Biol. Chem. |
pmid:12147693
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Khan AA et al. |
In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12152003
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Vecino AM et al. |
Phospholipase A2 activity in platelets of patients with uremia. |
2002 |
Platelets |
pmid:12487789
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Tzanakakis GN et al. |
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. |
2002 |
Int J Gastrointest Cancer |
pmid:12630766
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Rinder HM et al. |
Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. |
2002 |
J Clin Pharmacol |
pmid:12162470
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Wong DA et al. |
Discrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2). |
2002 |
J. Exp. Med. |
pmid:12163563
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Kiemer AK et al. |
Inhibition of cyclooxygenase-2 by natriuretic peptides. |
2002 |
Endocrinology |
pmid:11861506
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Huang K et al. |
Role of selenium in cytoprotection against cholesterol oxide-induced vascular damage in rats. |
2002 |
Atherosclerosis |
pmid:11947907
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Hu X et al. |
[The influence of nasal continual positive airway pressure on some vasoactive substances in patients with obstructive sleep apnea syndrome]. |
2002 |
Zhonghua Jie He He Hu Xi Za Zhi |
pmid:11953098
|
Burleigh ME et al. |
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. |
2002 |
Circulation |
pmid:11956125
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Giardiello FM et al. |
Primary chemoprevention of familial adenomatous polyposis with sulindac. |
2002 |
N. Engl. J. Med. |
pmid:11932472
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Yamasaki M et al. |
No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs. |
2002 |
Eur. J. Pharmacol. |
pmid:11937106
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Eikelboom JW et al. |
Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. |
2002 |
Circulation |
pmid:11940542
|
Knijff-Dutmer EA et al. |
Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclo-oxygenase-2-selective inhibitors in patients with rheumatoid arthritis. |
2002 |
Rheumatology (Oxford) |
pmid:11961179
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Hayashi M et al. |
The levels of five markers of hemostasis and endothelial status at different stages of normotensive pregnancy. |
2002 |
Acta Obstet Gynecol Scand |
pmid:11966476
|
Leese PT et al. |
Valdecoxib does not impair platelet function. |
2002 |
Am J Emerg Med |
pmid:12098171
|
Tsukamoto H et al. |
Simultaneous quantification of prostaglandins, isoprostane and thromboxane in cell-cultured medium using gas chromatography-mass spectrometry. |
2002 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:12076690
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Sakai H et al. |
E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon. |
2002 |
Br. J. Pharmacol. |
pmid:12023941
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Jung K et al. |
The effect of dietary intervention through the modification of fatty acids composition and antioxidant vitamin intake on plasma TXB(2) level in Korean postmenopausal women with hypercholesterolemia. |
2002 |
J. Korean Med. Sci. |
pmid:12068132
|
Jung YS et al. |
Antithrombotic effect of onion in streptozotocin-induced diabetic rat. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12054917
|
van Kraaij DJ et al. |
A comparison of the effects of nabumetone vs meloxicam on serum thromboxane B2 and platelet function in healthy volunteers. |
2002 |
Br J Clin Pharmacol |
pmid:12047490
|
Appleyard CB et al. |
Temporal changes in colonic vascular architecture and inflammatory mediator levels in animal models of colitis. |
2002 |
Dig. Dis. Sci. |
pmid:12353846
|
Valeri CR et al. |
Circulation and hemostatic function of autologous fresh, liquid-preserved, and cryopreserved baboon platelets transfused to correct an aspirin-induced thrombocytopathy. |
2002 |
Transfusion |
pmid:12430680
|
Wilner KD et al. |
Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers. |
2002 |
J Clin Pharmacol |
pmid:12211219
|
Molina V et al. |
D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12213431
|
Koizumi T et al. |
Inhibition of endogenous nitric oxide during endotoxemia in awake sheep - effects of Nomega-nitro-l-arginine on the distribution of pulmonary vascular resistance and prostanoid products. |
2002 |
Exp. Lung Res. |
pmid:12217213
|
Khan I et al. |
Altered expression of Na(+)/H(+) exchanger isoforms 1 and 3 in clipped and unclipped kidneys of a 2-kidney-1-clip Goldblatt model of hypertension. |
2002 |
Nephron |
pmid:12218313
|
Yokoyama C et al. |
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. |
2002 |
Circulation |
pmid:12403673
|
Evgenov OV et al. |
Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep. |
2002 |
Eur. Respir. J. |
pmid:12412689
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Bergh K et al. |
Production of prostaglandin e(2) by iridial melanocytes exposed to latanoprost acid, a prostaglandin F(2 alpha) analogue. |
2002 |
J Ocul Pharmacol Ther |
pmid:12419090
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Chen TL et al. |
[Effects of fast decompression on prostaglandins content in cerebral tissue of guinea pigs]. |
2002 |
Space Med Med Eng (Beijing) |
pmid:12222577
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Kim H et al. |
Effect of mannitol on Helicobacter pylori-induced cyclooxygenase-2 expression in gastric epithelial AGS cells. |
2002 |
Pharmacology |
pmid:12393940
|
Shashikant MP et al. |
Physicochemical properties of perfluorochemical liquids influence ventilatory requirements, pulmonary mechanics, and microvascular permeability during partial liquid ventilation following intestinal ischemia/reperfusion injury. |
2002 |
Crit. Care Med. |
pmid:12394959
|
Vaughan JE and Walsh SW |
Oxidative stress reproduces placental abnormalities of preeclampsia. |
2002 |
Hypertens Pregnancy |
pmid:12517328
|