Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Weight Loss D015431 56 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Tai HH and Yuan B Development of radioimmunoassay for thromboxane B2. 1978 Anal. Biochem. pmid:567443
Murota S and Morita I Effect of prostaglandin I2 and related compounds on vascular permeability response in granuloma tissues. 1978 Prostaglandins pmid:635221
Powell WS and Solomon S Biosynthesis of prostaglandins and thromboxane B2 by fetal lung homogenates. 1978 Prostaglandins pmid:635224
Tai HH et al. Transformation of arachidonate into 6-oxoprostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 by sheep lung microsomal fraction. 1978 Biochem. J. pmid:637853
Raz A and Aharony D Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. 1978 Res. Commun. Chem. Pathol. Pharmacol. pmid:705027
Chang WC et al. Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma. 1978 Biochem. Pharmacol. pmid:619892
Goetzl EJ and Gorman RR Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT). 1978 J. Immunol. pmid:621391
Lagarde M et al. Impairment of platelet thromboxane A2 generation and of the platelet release reaction in two patients with congenital deficiency of platelet cyclo-oxygenase. 1978 Br. J. Haematol. pmid:205238
Crawford A et al. Rat osteogenic sarcoma cells: comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1alpha and thromboxane B2 on cyclic AMP production and adenylate cyclase activity. 1978 Biochem. Biophys. Res. Commun. pmid:212039
Trang LE et al. Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis. 1977 Scand. J. Rheumatol. pmid:929121
Smith AG et al. Gas-liquid chromatography-mass spectrometry of thromboxane B2 and its detection in semen and human aorta by selected ion monitoring. 1977 J. Chromatogr. pmid:562354
Abdel-Halim MS et al. Identification of prostaglandin D2 as a major prostaglandin in homogenates of rat brain. 1977 Prostaglandins pmid:594367
Williams KI and Downing I Prostaglandin and thromboxane production by rat decidual microsomes. 1977 Prostaglandins pmid:594385
Ali M et al. Synthesis of thromboxane B2 and prostaglandins by bovine gastric mucosal microsomes. 1977 Prostaglandins pmid:594386
Wasserman MA and Griffin RL Thromboxane B2--comparative bronchoactivity in experimental systems. 1977 Eur. J. Pharmacol. pmid:590340
Poyser NL Identification of thromboxane B2 in guinea-pig uterine homogenates. 1977 Experientia pmid:590434
Fitzpatrick FA et al. A radioimmunoassay for thromboxane B2. 1977 Anal. Biochem. pmid:907115
Murota SI et al. The effects of thromboxane B2 and 6-ketoprostaglandin F1alpha on cultured fibroblasts. 1977 Biochim. Biophys. Acta pmid:911847
Roberts LJ et al. Metabolism of thromboxane B2 in man. Identification of the major urinary metabolite. 1977 J. Biol. Chem. pmid:914816
Ali M et al. Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. 1977 Thromb. Res. pmid:918907
Burka JF and Garland LG A possible modulatory role for prostacyclin (PGI2) INIgGa-induced release of slow-reacting substance of anaphylaxis in rats. 1977 Br. J. Pharmacol. pmid:339980
Knapp HR et al. Ionophores stimulate prostaglandin and thromboxane biosynthesis. 1977 Proc. Natl. Acad. Sci. U.S.A. pmid:270668
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