Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Weight Loss D015431 56 associated lipids
Asthma D001249 52 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Saldeen P et al. Increased synthesis of thromboxane B2 and 6-keto-PGF1 alpha in hand veins from patients with deep venous thrombosis. 1983 Thromb. Res. pmid:6658723
Menys VC and Davies JA Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. 1983 Clin. Sci. pmid:6190604
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Nerlich M et al. Effect of thermal injury on endotoxin-induced lung injury. 1983 Surgery pmid:6337423
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Henriksen RA and Brotherton AF Evidence that activation of platelets and endothelium by thrombin involves distinct sites of interaction. Studies with the dysthrombin, Thrombin Quick I. 1983 J. Biol. Chem. pmid:6358210
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Ku EC et al. Characterization of imidazo[1,5-a]pyridine-5-hexanoic acid (CGS 13080) as a selective thromboxane synthetase inhibitor using in vitro and in vivo biochemical models. 1983 Biochem. Biophys. Res. Commun. pmid:6687803
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Tsukatani E Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6688085
Fischer S et al. In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue. 1983 Biochem. Pharmacol. pmid:6688182
Bailey IA et al. Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. 1983 Cardiovasc. Res. pmid:6688202
Srivastava KC and Awasthi KK Separation and quantitative determination of radiolabeled prostaglandins, thromboxanes, 6-keto-prostaglandin F1 alpha and other arachidonic acid metabolites produced in biological material. 1983 J. Chromatogr. pmid:6688256
Cortellaro M et al. Transcoronary platelet thromboxane A2 formation without platelet trapping in patients with coronary stenosis-effect of sulphinpyrazone treatment. 1983 Thromb. Haemost. pmid:6665767
De Caterina R et al. Antiplatelet effects of isosorbide dinitrate in man. 1983 Z Kardiol pmid:6666233
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Sakanishi N et al. [Effect of reduced glutathione on endotoxin shock]. 1983 Masui pmid:6668649
Moonen P et al. An improved method for separation of thromboxane B2 by reversed phase liquid chromatography. 1983 Prostaglandins pmid:6669711
Reuben SR et al. Effects of dazoxiben on exercise performance in chronic stable angina. 1983 Br J Clin Pharmacol pmid:6402000
Mahoney DP et al. Radioimmunoassay of prostaglandins and thromboxane B2 in extracted and unextracted urine and serum using an iodinated ligand. 1983 Prostaglandins Leukot Med pmid:6579570
Güllner HG et al. Renal thromboxane excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin treatment. 1983 Prostaglandins Leukot Med pmid:6580653
Rojas J et al. Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. 1983 Pediatr. Res. pmid:6402752
Sakanishi N et al. Thromboxane A2 and hemodynamic-biochemical parameters in canine endotoxin shock. 1983 Bull. Tokyo Med. Dent. Univ. pmid:6580966
Förster W and Pönicke K Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. 1983 Br. J. Pharmacol. pmid:6403094
Orlandi M et al. Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes. 1983 Prostaglandins Leukot Med pmid:6583712
Männistö J and Uotila P Cigarette smoke ventilation decreases thromboxane B2 metabolism in isolated rat lungs. 1983 Prostaglandins Leukot Med pmid:6583713
Nenci GG et al. Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. 1983 Haemostasis pmid:6404715
Sharon P et al. Prostanoid synthesis by cultured gastric and duodenal mucosa: Possible role in the pathogenesis of duodenal ulcer. 1983 Scand. J. Gastroenterol. pmid:6584967
Carr BR et al. Prostaglandin secretion by the neocortex and fetal zones of the human fetal adrenal gland. 1983 J. Clin. Endocrinol. Metab. pmid:6313732