Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
beta-Thalassemia D017086 5 associated lipids
Carotid Stenosis D016893 15 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Yang Deficiency D016711 3 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bacteremia D016470 9 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Tanaka S et al. High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. 2003 Chest pmid:14605047
Pestel S et al. Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. 2003 Biochem. Pharmacol. pmid:12906929
Patel YM et al. Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder. 2003 Blood pmid:12609843
Hausman N et al. Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit. 2003 Prostaglandins Other Lipid Mediat. pmid:12611495
Basta M et al. F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. 2003 Nat. Med. pmid:12612546
Fiorucci S et al. Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study. 2003 Gastroenterology pmid:12612897
Vigorita MG et al. Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. 2003 Bioorg. Med. Chem. pmid:12614885
Reid G et al. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12835412
Bosetti F et al. Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. 2003 J. Neurochem. pmid:12694395
Tanaka Y et al. Effects of exercise on platelet and aortic functions in aged rats. 2003 Acta Physiol. Scand. pmid:14510779
Ziser A et al. Propofol does not induce pulmonary dysfunction in stressed endotoxic pigs receiving Intralipid. 2003 Crit. Care Med. pmid:12847400
Chen Z et al. [Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis]. 2003 Zhong Xi Yi Jie He Xue Bao pmid:15339561
He LQ et al. [Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy]. 2003 Zhong Xi Yi Jie He Xue Bao pmid:15339583
Al-Waili NS and Boni NS Natural honey lowers plasma prostaglandin concentrations in normal individuals. 2003 J Med Food pmid:12935324
Jones AE et al. Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. 2003 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:12639842
Davì G et al. Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. 2003 Circulation pmid:12810609
Montuschi P et al. Exhaled leukotrienes and prostaglandins in COPD. 2003 Thorax pmid:12832671
Wolfram RM et al. Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids. 2003 Life Sci. pmid:14575812
Beck-Speier I et al. Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. 2003 Prostaglandins Other Lipid Mediat. pmid:14518563
Sartin JL et al. Estradiol plus progesterone treatment modulates select elements of the proinflammatory cytokine cascade in steers: attenuated nitric oxide and thromboxane B2 production in endotoxemia. 2003 J. Anim. Sci. pmid:12817503
Ojanen R et al. Single dose of acetylsalicylic acid prevents thromboxane release after tourniquet ischemia. 2003 J Trauma pmid:12777914
Dionne RA et al. Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation. 2003 J. Oral Maxillofac. Surg. pmid:12966473
Tsipas G and Morphake P Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. 2003 J. Nutr. Biochem. pmid:12948879
Cerletti C et al. Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. 2003 Clin Pharmacokinet pmid:12959636
Davì G et al. Platelet activation in obese women: role of inflammation and oxidant stress. 2002 Oct 23-30 JAMA pmid:12387653
Hayashi M et al. Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. 2002 Nov-Dec Eur. J. Haematol. pmid:12460234
Wolfram RM et al. Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers. 2002 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:12144875
Alarayyed NA et al. Differential actions of naftopidil, doxazosin and nifedipine on platelet thromboxane generation and platelet-derived growth factor efflux in vitro. 2002 Aug-Sep Platelets pmid:12189011
Schelzig H et al. Role of recombinant hirudin in a pig-to-human lung transplantation model. 2002 Transplant. Proc. pmid:12270449
Huang CG et al. Effect of berberine on arachidonic acid metabolism in rabbit platelets and endothelial cells. 2002 Thromb. Res. pmid:12297129
Lees P and Landoni MF Pharmacodynamics and enantioselective pharmacokinetics of racemic carprofen in the horse. 2002 J. Vet. Pharmacol. Ther. pmid:12485349
Tang L et al. [Relationship between cyclooxygenase-2 protein expression, prostaglandins levels and biologic behavior in ovarian carcinoma tissue]. 2002 Zhonghua Fu Chan Ke Za Zhi pmid:12487927
Tuersun K and Huang Y [Changes of blood vessel active substances in acute pulmonary embolism induced by echinococus granulous cyst in rabbits]. 2002 Zhonghua Jie He He Hu Xi Za Zhi pmid:12490126
Zaitsu M et al. Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12468261
Minuz P et al. Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. 2002 Circulation pmid:12451006
Bruno A et al. Aspirin and urinary 11-dehydrothromboxane B(2) in African American stroke patients. 2002 Stroke pmid:11779889
Kudolo GB et al. Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. 2002 Thromb. Res. pmid:12590952
Tzanakakis GN et al. The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. 2002 Int J Gastrointest Cancer pmid:12630766
Kirchheiner J et al. Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. 2002 Clin. Pharmacol. Ther. pmid:12152005
Wang L et al. Enhancement of human platelet activation by the combination of low concentrations of collagen and rabbit anticardiolipin antibodies. 2002 Br. J. Haematol. pmid:12199800
Park CH et al. Investigations of new lead structures for the design of novel cyclooxygenase-2 inhibitors. 2002 Eur J Med Chem pmid:12204472
Cipollone F et al. Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy. 2002 Circulation pmid:12135935
Association between ibuprofen, aspirin therapy found. 2002 J Am Dent Assoc pmid:12136787
Rinder HM et al. Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. 2002 J Clin Pharmacol pmid:12162470
Saldeen P et al. Structural, functional and circulatory placental changes associated with impaired glucose metabolism. 2002 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:12381475
Zhang H et al. [Perioperative lung injury in ventricular septal defect with severe pulmonary hypertension, a clinical study of 31 cases]. 2002 Zhonghua Yi Xue Za Zhi pmid:12425808
Jones CJ et al. In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs. 2002 Am. J. Vet. Res. pmid:12428662
Buluç M et al. Effect of misoprostol and indomethacin on cyclooxygenase induction and eicosanoid production in carrageenan-induced air pouch inflammation in rats. 2002 Prostaglandins Other Lipid Mediat. pmid:12428691
Gray PA et al. Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. 2002 Br. J. Pharmacol. pmid:12429575
Ferlito M et al. Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production. 2002 J. Endotoxin Res. pmid:12701623