Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
beta-Thalassemia D017086 5 associated lipids
Carotid Stenosis D016893 15 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Yang Deficiency D016711 3 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bacteremia D016470 9 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Parker CW et al. Formation of thromboxane B2 and hydroxyarachidonic acids in purified human lymphocytes in the presence and absence of PHA. 1979 J. Immunol. pmid:448099
Needleman P et al. Platelet and blood vessel arachidonate metabolism and interactions. 1979 J. Clin. Invest. pmid:372240
Morley J et al. Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. 1979 Prostaglandins pmid:493559
Meyers KM et al. A dominant role of thromboxane formation in secondary aggregation of platelets. 1979 Nature pmid:503210
de Deckere EA et al. Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. 1979 Prostaglandins pmid:504696
Powell WS Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits. 1979 Biochim. Biophys. Acta pmid:518891
Spagnuolo C et al. Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. 1979 Prostaglandins pmid:523683
Bennett A and Sanger GJ Trimethoquinol selectively antagonises longitudinal muscle contractions of rat isolated gastric fundus to thromboxane B2 and epoxymethano analogues of PGH2 [proceedings]. 1979 Br. J. Pharmacol. pmid:526738
Prancan AV et al. L8027 and 1-nonyl-imidazole as non-selective inhibitors of thromboxane synthesis. 1979 Eur. J. Pharmacol. pmid:527664
Daniel EE et al. Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. 1979 Prostaglandins pmid:379920
Russell FA and Deykin D The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. 1979 Prostaglandins pmid:523671
Roberts LJ et al. Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. 1979 Biochim. Biophys. Acta pmid:389290
Dutilh CE et al. Study of the two pathways for arachidonate oxygenation in blood platelets. 1979 Lipids pmid:34075
Kelly JP et al. Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. 1979 J. Immunol. pmid:109510
Whittle BJ Prostaglandin synthetase inhibitors. Drugs which affect arachidonic acid metabolism. 1979 Acta Obstet Gynecol Scand Suppl pmid:111464
Robinson JS et al. Prostaglandin E, thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid and maternal plasma of rhesus monkeys (Macaca mulatta) during the latter third of gestation. 1979 J. Endocrinol. pmid:112214
Burch RM et al. Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole. 1979 J. Pharmacol. Exp. Ther. pmid:113526
Ford-Hutchinson AW et al. The aggregation of rat neutrophils by arachidonic acid: a possible bioassay for lipoxygenase activity. 1979 J. Pharm. Pharmacol. pmid:43380
Dembińska-Kièć A et al. Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits. 1979 Atherosclerosis pmid:224890
Kass MA and Holmberg NJ Prostaglandin and thromboxane synthesis by microsomes of rabbit ocular tissues. 1979 Invest. Ophthalmol. Vis. Sci. pmid:761971