Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypercapnia D006935 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Asthenia D001247 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Placenta Diseases D010922 5 associated lipids
Thrombophilia D019851 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Coronary Stenosis D023921 6 associated lipids
Sneezing D012912 6 associated lipids
Thromboembolism D013923 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Sanger GJ and Bennett A Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. 1980 Adv Prostaglandin Thromboxane Res pmid:6103666
Morris HG and Sherman NA Prostaglandin-like substances in urine of asthmatic patients. 1980 Adv Prostaglandin Thromboxane Res pmid:7377024
Schoene NW et al. Effects of diets varying in fat and P/S ratio on arachidonic acid metabolism in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:7377026
Patrono C et al. Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. 1980 Adv Prostaglandin Thromboxane Res pmid:7386257
Langs DA et al. Thromboxane molecules are not hairpin conformers. 1980 Adv Prostaglandin Thromboxane Res pmid:7386281
Bailey JM Essential fatty acid requirements and metabolism of cells in tissue culture. 1980 Adv Prostaglandin Thromboxane Res pmid:7386288
Feinstein MB et al. Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6770602
Flynn JT and Demling RH Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. 1982 Adv Shock Res pmid:6753534
Lefer AM and Crossley K Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. 1980 Adv Shock Res pmid:7304314
Hori Y et al. Interaction of endogenous kinins and prostaglandins in the plasma exudation of kaolin-induced pleurisy in rats. 1989 Adv. Exp. Med. Biol. pmid:2481952
Moncada S and Whittle BJ Biological actions of prostacyclin and its pharmacological use in platelet studies. 1985 Adv. Exp. Med. Biol. pmid:3010671
Bourgeois N et al. Effects of endotoxin on hemodynamics of isolated dog kidney. 1987 Adv. Exp. Med. Biol. pmid:3303858
Hadding U et al. Peritoneal macrophages release prostaglandin E and thromboxane B2 in response to C3b. 1982 Adv. Exp. Med. Biol. pmid:7158499
Novo S et al. Platelet activity in relation to smoke and exercise in patients with chronic obstructive lung disease: effects of platelet antiaggregating drugs. 1984 Adv. Exp. Med. Biol. pmid:6546467
Davì G et al. Platelet function changes in acute myocardial infarction. 1984 Adv. Exp. Med. Biol. pmid:6695571
Suchkova V Prostanoid and anti-thrombin III levels in premature infants. 1997 Adv. Exp. Med. Biol. pmid:9547655
Yoshida T et al. Improvement of renal function with selective thromboxane A2 synthetase inhibitor, DP-1904 in lupus nephritis. 1997 Adv. Exp. Med. Biol. pmid:9561116
Müller M In vivo measurement of interstitial TxB2-concentrations in skeletal muscle during ischemia and reperfusion. 1997 Adv. Exp. Med. Biol. pmid:9561122
Arbogast E et al. Intrauterine eicosanoid production in uncomplicated and hypertensive pregnancies: alterations of placental 12-hydroxyeicosatetraenoic acid. 1997 Adv. Exp. Med. Biol. pmid:9561182
Lecompte T et al. Radioimmunoassay for 11-dehydro-thromboxane B2 using an iodinated ligand: preliminary applications to human fluids. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960162