Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Placenta Diseases D010922 5 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Facial Pain D005157 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypercapnia D006935 5 associated lipids
Asthenia D001247 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Coronary Stenosis D023921 6 associated lipids
Sneezing D012912 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Thromboembolism D013923 6 associated lipids
Thrombophilia D019851 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
DeFilippis AP et al. Fatty acids and TxA(2) generation, in the absence of platelet-COX-1 activity. 2014 Nutr Metab Cardiovasc Dis pmid:24370448
Togna AR et al. 4-Methylcoumarin derivatives with anti-inflammatory effects in activated microglial cells. 2014 Biol. Pharm. Bull. pmid:24389482
Osmond DA et al. Clopidogrel preserves whole kidney autoregulatory behavior in ANG II-induced hypertension. 2014 Am. J. Physiol. Renal Physiol. pmid:24477682
Cathcart MC et al. Thromboxane synthase expression and correlation with VEGF and angiogenesis in non-small cell lung cancer. 2014 Biochim. Biophys. Acta pmid:24480048
Chou YI et al. Correlations of platelet-derived microparticles with thromboxane B2, platelet-activating factor, endothelin-1, and neutrophil to lymphocyte ratio in patients with coronary intermediate lesions. 2014 Biomarkers pmid:25391885
Wang Y et al. DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4. 2014 BMC Complement Altern Med pmid:24555740
Fuentes E et al. A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities. 2014 Nutrients pmid:25514563
Santos-Gallego CG and Badimon JJ The sum of two evils: pneumonia and myocardial infarction: is platelet activation the missing link? 2014 J. Am. Coll. Cardiol. pmid:25444148
Cangemi R et al. Platelet activation is associated with myocardial infarction in patients with pneumonia. 2014 J. Am. Coll. Cardiol. pmid:25444147
Reddoch KM et al. Hemostatic function of apheresis platelets stored at 4°C and 22°C. 2014 Shock pmid:24169210