| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cleft Palate | D002972 | 9 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Contusions | D003288 | 3 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Coronary Thrombosis | D003328 | 7 associated lipids |
| Coronary Vasospasm | D003329 | 9 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Death, Sudden | D003645 | 12 associated lipids |
| Dermatitis, Atopic | D003876 | 19 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetic Angiopathies | D003925 | 20 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Diabetic Retinopathy | D003930 | 39 associated lipids |
| Diseases in Twins | D004200 | 4 associated lipids |
| Disseminated Intravascular Coagulation | D004211 | 7 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kallmann R et al. | Effects of low doses of aspirin, 10 mg and 30 mg daily, on bleeding time, thromboxane production and 6-keto-PGF1 alpha excretion in healthy subjects. | 1987 | Thromb. Res. | pmid:3576521 |
| Schorer AE | Discordant effects on eicosanoids and fibrin degradation products in two murine models of antiphospholipid antibody. | 1997 | Thromb. Res. | pmid:9062953 |
| Kosaki G et al. | The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. | 1980 Dec 1-15 | Thromb. Res. | pmid:6785893 |
| Anfossi G et al. | Studies on in vitro effect of picotamide on human platelet aggregation in platelet-rich plasma and whole blood. | 1995 | Thromb. Res. | pmid:7778055 |
| Watanabe T et al. | Enhanced platelet sensitivity to prostacyclin in patients in an active stage of Takayasu arteritis. | 2001 | Thromb. Res. | pmid:11672751 |
| Carroll RC et al. | Post interventional cardiology urinary thromboxane correlates with PlateletMapping detected aspirin resistance. | 2010 | Thromb. Res. | pmid:19962724 |
| Lee GY et al. | Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester. | 2005 | Thromb. Res. | pmid:15668191 |
| Ziegler BK et al. | Incomplete thromboxane inhibition with 100 mg of intravenous acetylsalicylic acid in patients with acute ST elevation myocardial infarction: a placebo-controlled pilot trial. | 2001 | Thromb. Res. | pmid:11672759 |
| Ersöz G et al. | The effect of submaximal exercise on platelet aggregation during late follicular and midluteal phases in women. | 2002 | Thromb. Res. | pmid:12590951 |
| Kawamura M et al. | Evaluation of plasma 11-dehydro-thromboxane B2 as an indicator for thromboxane A2 synthesis in vivo in laboratory animals. | 1995 | Thromb. Res. | pmid:7778061 |
| Winter M et al. | Synthesis of thromboxane B2 in uraemia and the effects of dialysis. | 1983 | Thromb. Res. | pmid:6868024 |
| Ersöz G et al. | Effect of sodium selenite treatment on platelet aggregation of streptozotocin-induced diabetic rats. | 2003 | Thromb. Res. | pmid:14698654 |
| Teng CM et al. | Two antiplatelet agents from Magnolia officinalis. | 1988 | Thromb. Res. | pmid:3413728 |
| Addonizio VP et al. | Inhibition of human platelet function by verapamil. | 1982 | Thromb. Res. | pmid:7164035 |
| Pekonen F et al. | Platelet function and coagulation in normal and preeclamptic pregnancy. | 1986 | Thromb. Res. | pmid:2944245 |
| Vargaftig BB et al. | Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets. | 1982 | Thromb. Res. | pmid:7164036 |
| Vlodavsky I et al. | Platelet interaction with the extracellular matrix produced by cultured endothelial cells: a model to study the thrombogenicity of isolated subendothelial basal lamina. | 1982 | Thromb. Res. | pmid:7179215 |
| Cholette JM et al. | Aspirin resistance following pediatric cardiac surgery. | 2010 | Thromb. Res. | pmid:20550971 |
| Umemura K et al. | Effect of dietary docosahexaenoic acid in the rat middle cerebral artery thrombosis model. | 1995 | Thromb. Res. | pmid:7660354 |
| Chou TC and Li CY | Inhibitory mechanisms of dantrolene on platelet aggregation. | 1999 | Thromb. Res. | pmid:10593433 |
| Carter AJ et al. | Human pulmonary vessels obtained from necropsy produce less prostacyclin and thromboxane than fresh vessels obtained from operations. | 1984 | Thromb. Res. | pmid:6547546 |
| Cerskus AL et al. | Effects of indomethacin and sulfinpyrazone on in vivo formation of thromboxane B2 and prostaglandin D2 during arachidonate infusion in rabbits. | 1978 | Thromb. Res. | pmid:653641 |
| Hernández R et al. | Influence of co-incubation and cell number of platelets and polymorphonuclear leukocytes in cellular inhibition and activation phenomena. | 1994 | Thromb. Res. | pmid:8042192 |
| Rousson D et al. | Acute myocardial infarction: measurement of arachidonate end-products in whole blood as an index of platelet cyclo-oxygenase activity in vivo. | 1987 | Thromb. Res. | pmid:3122356 |
| Hanasaki K and Arita H | Characterization of a new compound, S-145, as a specific TXA2 receptor antagonist in platelets. | 1988 | Thromb. Res. | pmid:2839912 |
| Navran SS et al. | Human platelet activation by bacterial phospholipase C is mediated by phosphatidylinositol hydrolysis but not generation of phosphatidic acid: inhibition by a selective inhibitor of phospholipase C. | 1984 | Thromb. Res. | pmid:6372157 |
| Shorr RI et al. | In vitro effects of acetaminophen and its analogues on human platelet aggregation and thromboxane B2 synthesis. | 1985 | Thromb. Res. | pmid:3923647 |
| Vanags D et al. | The antiplatelet effect of daily low dose enteric-coated aspirin in man: a time course of onset and recovery. | 1990 | Thromb. Res. | pmid:2264023 |
| Ishikawa Y et al. | Effect of cytoplasmic pH on platelet activation by arachidonic acid. | 1989 | Thromb. Res. | pmid:2499076 |
| Kankuri E et al. | Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. | 2003 | Thromb. Res. | pmid:14592552 |
| Lages B and Weiss HJ | Inhibition of human platelet function in vitro and ex vivo by acetaminophen. | 1989 | Thromb. Res. | pmid:2499947 |
| Küster LJ et al. | Mechanism of PAF-induced platelet aggregation in man. | 1986 | Thromb. Res. | pmid:3764802 |
| Reimers HJ et al. | Impaired thromboxane synthesis in preactivated human blood platelets: agonist-specific, irreversible desensitization to thrombin. | 1987 | Thromb. Res. | pmid:3126557 |
| Stegmeier K et al. | The pharmacological profile of the thromboxane A2 antagonist BM 13.177. A new anti-platelet and anti-thrombotic drug. | 1984 | Thromb. Res. | pmid:6385334 |
| Mercer JB et al. | The effect of short-term cold exposure on risk factors for cardiovascular disease. | 1999 | Thromb. Res. | pmid:10418798 |
| Perneby C et al. | Prothrombotic responses to exercise are little influenced by clopidogrel treatment. | 2004 | Thromb. Res. | pmid:15381386 |
| Hall ER et al. | The reduction of platelet thrombi on damaged vessel wall by a thromboxane synthetase inhibitor in rabbits. | 1982 | Thromb. Res. | pmid:6891109 |
| Lukasik M et al. | Aspirin treatment influences platelet-related inflammatory biomarkers in healthy individuals but not in acute stroke patients. | 2011 | Thromb. Res. | pmid:21788065 |
| Davis RB et al. | Evaluation of platelet function in pregnancy. Comparative studies in non-smokers and smokers. | 1987 | Thromb. Res. | pmid:2955542 |
| Gerrard JM et al. | Studies in patients with bleeding disorders show that platelet-vessel interaction is important for thromboxane formation in bleeding time wounds. | 1990 | Thromb. Res. | pmid:2278038 |
| Suehiro A et al. | The role of platelet hyperfunction in thrombus formation in hyperlipidemia. | 1982 | Thromb. Res. | pmid:6803387 |
| Ali M et al. | Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. | 1977 | Thromb. Res. | pmid:918907 |
| Vericel E et al. | Platelets and aging. I--Aggregation, arachidonate metabolism and antioxidant status. | 1988 | Thromb. Res. | pmid:3129819 |
| Wang JP et al. | Antiplatelet effect of capsaicin. | 1984 | Thromb. Res. | pmid:6528310 |
| Cattaneo M et al. | In vitro effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production. | 1991 | Thromb. Res. | pmid:1926062 |
| Udvardy M et al. | Alterations of primary haemostasis in mixed connective tissue disease (MCTD). | 1991 | Thromb. Res. | pmid:1835548 |
| Koh H et al. | A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. | 1980 Feb 1-15 | Thromb. Res. | pmid:7368170 |
| Kohda N et al. | Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery. | 1999 | Thromb. Res. | pmid:10593428 |
| Marasini B et al. | Cigarette smoking and platelet function. | 1986 | Thromb. Res. | pmid:3787563 |
| Matsuo T et al. | A new thrombin inhibitor MD805 and thrombocytopenia encountered with heparin hemodialysis. | 1986 | Thromb. Res. | pmid:3787568 |
| Deckmyn H et al. | Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. | 1983 | Thromb. Res. | pmid:6344317 |
| Nosál' R et al. | Chloroquine: a multipotent inhibitor of human platelets in vitro. | 2000 | Thromb. Res. | pmid:10828481 |
| Buchanan MR et al. | The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. | 1983 | Thromb. Res. | pmid:6221436 |
| Neiman J et al. | Composition of platelet phosphatidylinositol and phosphatidylcholine after ethanol withdrawal. | 1987 | Thromb. Res. | pmid:3603426 |
| Randall MJ and Wilding RI | Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01). | 1982 | Thromb. Res. | pmid:6897751 |
| Di Minno G and Violi F | Aspirin resistance and diabetic angiopathy: back to the future. | 2004 | Thromb. Res. | pmid:15115664 |
| Vesterqvist O et al. | Development of a GC-MS method for quantitation of 2,3-dinor-TxB2 and determinations of the daily urinary excretion rates in healthy humans. | 1984 | Thromb. Res. | pmid:6695361 |
| Zijlstra FJ et al. | Thrombotic thrombocytopenic purpura and plasma thromboxane B2 levels. | 1983 | Thromb. Res. | pmid:6684333 |
| Todd MK et al. | Effect of exercise intensity on 6-keto-PGF1 alpha, TXB2, and 6-keto-PGF1 alpha/TXB2 ratios. | 1992 | Thromb. Res. | pmid:1615492 |
| Dembinska-Kiec A et al. | Ticlopidine and platelet function in healthy volunteers. | 1992 | Thromb. Res. | pmid:1615496 |
| Sandler H et al. | Studies on the role of thromboxane in thrombin-induced pulmonary insufficiency in the rat. | 1986 | Thromb. Res. | pmid:3754987 |
| Maguire ED and Wallis RB | In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. | 1983 | Thromb. Res. | pmid:6689221 |
| Hashimoto Y et al. | Characteristics of protein kinase C-independent exocytosis in human platelets. | 1997 | Thromb. Res. | pmid:9336873 |
| Igawa T et al. | Potentiation of anti-platelet aggregating activity of cilostazol with vascular endothelial cells. | 1990 | Thromb. Res. | pmid:2158154 |
| Di Minno MN et al. | Genotype-independent in vivo oxidative stress following a methionine loading test: maximal platelet activation in subjects with early-onset thrombosis. | 2011 | Thromb. Res. | pmid:21669453 |
| Ames PR et al. | Aspirin insensitive thromboxane generation is associated with oxidative stress in type 2 diabetes mellitus. | 2012 | Thromb. Res. | pmid:22521214 |
| McGill D et al. | Platelet function and exercise-induced myocardial ischaemia in coronary heart disease patients. | 1989 | Thromb. Res. | pmid:2533414 |
| Martin JF et al. | The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration. | 1983 | Thromb. Res. | pmid:6658722 |
| Li C et al. | Aspirin response variability after major orthopedic surgery. | 2012 | Thromb. Res. | pmid:22575418 |
| Vesterqvist O et al. | In vivo production of thromboxane in acute human myocardial infarction: a preliminary study. | 1985 | Thromb. Res. | pmid:3992528 |
| Chiang TM and Kang AH | The effect of platelet surface protein phosphorylation on collagen-platelet interaction. | 1986 | Thromb. Res. | pmid:3810565 |
| Serebruany VL and Gurbel PA | Assessment of platelet activity by measuring platelet-derived substances in plasma from patients with acute myocardial infarction: surprising lessons from the GUSTO-III Platelet Study. | 1999 | Thromb. Res. | pmid:10030832 |
| Croft KD and Beilin LJ | Platelet and neutrophil function and eicosanoid release in a subject with abetalipoproteinaemia. | 1993 | Thromb. Res. | pmid:8385810 |
| Hofmann D et al. | Evidence for sustained platelet activation in patients with early postinfarction angina. | 1993 | Thromb. Res. | pmid:8303651 |
| Toft G et al. | Intravenously and topically applied magnesium in the prevention of arterial thrombosis. | 2000 | Thromb. Res. | pmid:10904104 |
| Knapp HR et al. | Effects of low-dose aspirin on endogenous eicosanoid formation in normal and atherosclerotic men. | 1988 | Thromb. Res. | pmid:3293263 |
| Sinzinger H et al. | Response of thromboxane B2, malondialdehyde and platelet sensitivity to 3 weeks low-dose aspirin (ASA) in healthy volunteers. | 1989 | Thromb. Res. | pmid:2497545 |
| Pirich C et al. | Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. | 1999 | Thromb. Res. | pmid:10588465 |
| De Caterina R et al. | Inhibition of platelet aggregation and thromboxane B2 production during aspirin treatment: dependence on the dose of the aggregating agent. | 1985 | Thromb. Res. | pmid:3975876 |
| Worthington RE and Fuller GC | Dibutyryl cyclic guanosine monophosphate elevates bovine endothelial cell thromboxane production without affecting prostacyclin metabolism. | 1984 | Thromb. Res. | pmid:6322377 |
| Selley ML et al. | The effect of cholesterol oxidation products on human platelet aggregation. | 1996 | Thromb. Res. | pmid:8885139 |
| Kritz H et al. | Isradipine increases vascular prostaglandin I2-formation while the thromboxane B2-synthesis is diminished. | 1995 | Thromb. Res. | pmid:8610276 |
| Bergqvist D et al. | The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis. | 1985 | Thromb. Res. | pmid:3838828 |
| Kelton JG et al. | Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. | 1981 Oct 1-15 | Thromb. Res. | pmid:7330835 |
| Yamaguchi A et al. | Effect of cetiedil on platelet aggregation and thromboxane synthesis. | 1985 | Thromb. Res. | pmid:2986312 |
| Lai LJ et al. | Trilinolein inhibits epinephrine-induced human platelet aggregation. | 1994 | Thromb. Res. | pmid:7863478 |
| Domoto DT et al. | Combined aspirin and sulfinpyrazone in the prevention of recurrent hemodialysis vascular access thrombosis. | 1991 | Thromb. Res. | pmid:1926064 |
| Ding YA et al. | Antiplatelet actions of 2-(4-[1-(2-chlorophenyl) piperazinyl]) methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one compound. | 1995 | Thromb. Res. | pmid:7740521 |
| Wang JP et al. | XC 386: a new antiplatelet agent. | 1984 | Thromb. Res. | pmid:6438827 |
| Schorer AE and White JG | Interleukin 1 enhances arterial thrombogenicity in vitro. | 1989 | Thromb. Res. | pmid:2609290 |
| Küster LJ and Frölich JC | PAF-induced platelet aggregation and TXB2 formation. | 1989 | Thromb. Res. | pmid:2922704 |
| Tzeng SH et al. | Inhibition of platelet aggregation by some flavonoids. | 1991 | Thromb. Res. | pmid:1776142 |
| Antonino MJ et al. | Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone. | 2010 | Thromb. Res. | pmid:19446864 |
| Udvardy M et al. | Altered primary haemostasis in Conn's syndrome. | 1992 | Thromb. Res. | pmid:1448795 |
| Altman R et al. | Why single daily dose of aspirin may not prevent platelet aggregation. | 1988 | Thromb. Res. | pmid:3140408 |
| Simmet T and Weide I | Thromboxane and cysteinyl-leukotriene formation are differentially activated in spontaneously clotting whole human blood in vitro. | 1991 | Thromb. Res. | pmid:1866709 |
| Lukaszyk A et al. | Does acute experimental pancreatitis affect blood platelet function? | 1989 | Thromb. Res. | pmid:2524119 |
| Delvos U et al. | Direct radioimmunological measurement of thromboxane B2 in plasma. | 1985 | Thromb. Res. | pmid:4082109 |
| Swart SS et al. | Functional significance of the platelet alpha2-adrenoceptor: studies in patients with myeloproliferative disorders. | 1984 | Thromb. Res. | pmid:6326344 |
| Meyers KM et al. | An evaluation of the arachidonate pathway of platelets from companion and food-producing animals, mink, and man. | 1980 | Thromb. Res. | pmid:7209869 |