Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hypertrophy, Left Ventricular D017379 12 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Cat Diseases D002371 12 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Death, Sudden D003645 12 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Polycythemia Vera D011087 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Eye Burns D005126 13 associated lipids
Acidosis D000138 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Uveitis D014605 14 associated lipids
Angina, Unstable D000789 14 associated lipids
Carotid Stenosis D016893 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Neutropenia D009503 15 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Choline Deficiency D002796 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Ulcer D014456 16 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Blister D001768 16 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Celiac Disease D002446 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Albuminuria D000419 18 associated lipids
Bronchial Spasm D001986 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Peptic Ulcer D010437 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Nephritis D009393 19 associated lipids
Cough D003371 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Byrne A et al. Continued thromboxane A2 formation despite administration of a platelet glycoprotein IIb/IIIa antagonist in patients undergoing coronary angioplasty. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9409315
Vezza R et al. Antivasoconstrictor and antiaggregatory activities of picotamide unrelated to thromboxane A2 antagonism. 1997 Thromb. Haemost. pmid:9408024
Knowles SO and Donaldson WE Lead disrupts eicosanoid metabolism, macrophage function, and disease resistance in birds. 1997 Oct-Nov Biol Trace Elem Res pmid:9404672
Wettstein M and Häussinger D Cytoprotection by the osmolytes betaine and taurine in ischemia-reoxygenation injury in the perfused rat liver. 1997 Hepatology pmid:9397998
Bellamy MC et al. Changes in inflammatory mediators during orthotopic liver transplantation. 1997 Br J Anaesth pmid:9389852
Li T et al. [Observation on TXB2 and 6-keto-PGF1 alpha in serum of patients with cor pulmonale]. 1996 Hua Xi Yi Ke Da Xue Xue Bao pmid:9389073
Liu Z [Effects of acupuncture on lipid, TXB2, 6-keto-PGF, alpha in simple obese patients complicated with hyperlipidemia]. 1996 Zhen Ci Yan Jiu pmid:9388312
Han JA and Hu WY [Progress in the study on protective effect of saponins Panax notoginseng on ischemic brain damage]. 1996 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9387754
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Xiao X et al. Effect of captopril on renal hemodynamics and renal prostaglandins in early type II diabetic patients with normo-or microalbuminuria. 1996 Chin. Med. Sci. J. pmid:9387403
Nygaard OP et al. The inflammatory properties of contained and noncontained lumbar disc herniation. 1997 Spine pmid:9383853
Kobayashi T et al. Changes in platelet calcium concentration by thromboxane A2 stimulation in patients with nephrotic syndrome of childhood. 1997 Nephron pmid:9375825
Savla U et al. Cyclic stretch of airway epithelium inhibits prostanoid synthesis. 1997 Am. J. Physiol. pmid:9374729
Farker K et al. Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women. 1997 Prostaglandins pmid:9373880
Siler-Khodr TM et al. The effect of dexamethasone on CRH and prostanoid production from human term placenta. 1997 Prostaglandins pmid:9373879
Capponi A et al. Indomethacin modifies the fetal hemodynamic response induced by percutaneous umbilical blood sampling. 1997 Am. J. Obstet. Gynecol. pmid:9369815
John H and Schlegel W Reversed-phase high-performance liquid chromatographic method for the determination of the 11-hydroxythromboxane B2 anomers equilibrium. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9367188
Riendeau D et al. Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. 1997 Can. J. Physiol. Pharmacol. pmid:9365818
Walker JS et al. Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis: support for the concept of "responders" and "nonresponders". 1997 Arthritis Rheum. pmid:9365082
Bar J et al. The regulation of platelet aggregation in vitro by interleukin-1beta and tumor necrosis factor-alpha: changes in pregnancy and in pre-eclampsia. 1997 Thromb. Haemost. pmid:9364994