Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Liver Cirrhosis, Biliary D008105 12 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Eye Burns D005126 13 associated lipids
Acidosis D000138 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Polycythemia Vera D011087 13 associated lipids
Angina, Unstable D000789 14 associated lipids
Uveitis D014605 14 associated lipids
Neutropenia D009503 15 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Carotid Stenosis D016893 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Celiac Disease D002446 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Choline Deficiency D002796 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Ulcer D014456 16 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Blister D001768 16 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Bronchial Spasm D001986 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Albuminuria D000419 18 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Peptic Ulcer D010437 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Nephritis D009393 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
Cough D003371 19 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Snapper JR et al. Effects of platelet depletion on the unanesthetized sheep's pulmonary response to endotoxemia. 1984 J. Clin. Invest. pmid:6501570
Sheehan DV et al. Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. 1984 J Clin Psychopharmacol pmid:6142907
Barnett AH et al. Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes. 1984 Lancet pmid:6145027
Deimann W et al. Endogenous peroxidase in the nuclear envelope and endoplasmic reticulum of human monocytes in vitro: association with arachidonic acid metabolism. 1984 Blood pmid:6331550
Schenkelaars EJ and Bonta IL Beta 2-adrenoceptor agonists reverse the leukotriene C4-induced release response of macrophages. 1984 Eur. J. Pharmacol. pmid:6151905
Irvine RF et al. One-dimensional thin-layer chromatographic separation of the lipids involved in arachidonic acid metabolism. 1984 J Pharmacol Methods pmid:6443136
Rainsford KD et al. Comparative effects of some non-steroidal anti-inflammatory drugs on the ultrastructural integrity and prostaglandin levels in the rat gastric mucosa: relationship to drug uptake. 1984 Scand. J. Gastroenterol. Suppl. pmid:6443622
Patrignani P et al. Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism. 1984 J. Pharmacol. Exp. Ther. pmid:6537977
Vesterqvist O and Gréen K Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions. 1984 Prostaglandins pmid:6539491
McCluskey ER et al. In vivo inhibition of thromboxane synthetase in infarcted canine myocardium. 1984 Biochem. Biophys. Res. Commun. pmid:6539597
Katz JM et al. Inhibition of prostaglandin action and bone resorption by copper. 1984 Ann. Rheum. Dis. pmid:6441529
Stahl RA et al. Angiotensin II stimulation of prostaglandin E2 and 6-keto-F1 alpha formation by isolated human glomeruli. 1984 Kidney Int. pmid:6592393
Le Breton GC et al. 2-(6-carboxyhexyl)cyclopentanone hexylhydrazone: a potent inhibitor of the blood platelet cyclo-oxygenase. 1984 Prostaglandins pmid:6427851
Moodley J et al. Amniotic fluid prostanoids in preeclampsia. 1984 Obstet Gynecol pmid:6547518
Carter AJ et al. Human pulmonary vessels obtained from necropsy produce less prostacyclin and thromboxane than fresh vessels obtained from operations. 1984 Thromb. Res. pmid:6547546
Takeda H et al. [A comparison of centrifugal and roller pumps. An experimental study]. 1984 Kyobu Geka pmid:6547750
Mitsuhashi N and Kato J Bioconversion of arachidonic acid to prostaglandins and related compounds in human myometrium and uterine cervix. 1984 Endocrinol. Jpn. pmid:6442700
Ehrlich HP Promotion of vascular patency in dermal burns with ibuprofen. 1984 Am. J. Med. pmid:6547810
Huval WV et al. Role of serotonin in patients with acute respiratory failure. 1984 Ann. Surg. pmid:6547816
Croft KD et al. Dietary modification of platelet and renal prostaglandins. 1984 Aust N Z J Med pmid:6393931
Croft KD et al. Dietary modification of fatty acid and prostaglandin synthesis in the rat. Effect of variations in the level of dietary fat. 1984 Biochim. Biophys. Acta pmid:6548159
Wada H et al. Effect of TEI-4120 (3-benzoyl-N-beta-ethoxyisopropyl-2-methlindole) on carrageenan induced disseminated intravascular coagulation (DIC) in rats. 1984 J. Pharmacobio-dyn. pmid:6548260
Johnston C et al. Prostacyclin and thromboxane in non-insulin dependent diabetes: the chlorpropamide alcohol flush reaction revisited. 1984 Clin. Sci. pmid:6548428
Nicod P et al. Acute systemic and coronary hemodynamic and serologic responses to cigarette smoking in long-term smokers with atherosclerotic coronary artery disease. 1984 J. Am. Coll. Cardiol. pmid:6548482
Okazaki K et al. [Measurement of prostaglandins in human bile juice]. 1984 Nihon Shokakibyo Gakkai Zasshi pmid:6549033
Garcia-Szabo RR et al. Comparison of alpha- and gamma-thrombin on lung fluid balance in anesthetized sheep. 1984 J Appl Physiol Respir Environ Exerc Physiol pmid:6549181
Heinonen PK and Metsä-Ketelä T Prostaglandin and thromboxane production in ovarian cancer tissue. 1984 Gynecol. Obstet. Invest. pmid:6396175
Takeda H et al. [Comparison of centrifugal pump (bio pump) with roller pump: clinical study]. 1984 Kyobu Geka pmid:6549344
Welton AF et al. Ro 22-3747: a new antiallergic agent for the treatment of immediate hypersensitivity diseases. 1984 J. Pharmacol. Exp. Ther. pmid:6198511
Hwang DH et al. Zinc deficiency affects neither platelet arachidonic acid metabolism nor platelet aggregation in rats. 1984 J. Nutr. pmid:6582232
Brown CG and Poyser NL Studies on ovarian prostaglandin production in relation to ovulation in the rat. 1984 J. Reprod. Fertil. pmid:6595406
Mitrovic D et al. Anti-inflammatory drugs, prostanoid and proteoglycan production by cultured bovine articular chondrocytes. 1984 Prostaglandins pmid:6595718
Kirton OC et al. The development of a model of subacute lung injury after intra-abdominal infection. 1984 Surgery pmid:6379962
Roy AC et al. Thromboxane A2 and prostacyclin levels in molar pregnancy. 1984 Br J Obstet Gynaecol pmid:6383461
Runkle B et al. Cardiovascular changes in group B streptococcal sepsis in the piglet: response to indomethacin and relationship to prostacyclin and thromboxane A2. 1984 Pediatr. Res. pmid:6384909
Stegmeier K et al. The pharmacological profile of the thromboxane A2 antagonist BM 13.177. A new anti-platelet and anti-thrombotic drug. 1984 Thromb. Res. pmid:6385334
Ritter JM Prostanoid synthesis by aortic rings in human blood: selective increase of prostacyclin mediated by a serum factor. 1984 Br. J. Pharmacol. pmid:6386089
Vicenzi E et al. Human mononuclear phagocytes from different anatomical sites differ in their capacity to metabolize arachidonic acid. 1984 Clin. Exp. Immunol. pmid:6432383
Schneidkraut MJ et al. Thromboxane and prostacyclin synthesis following whole body irradiation in rats. 1984 J Appl Physiol Respir Environ Exerc Physiol pmid:6386769
Puustinen T et al. Glucocorticoids do not decrease thromboxane and prostacyclin levels in human blood. 1984 Prostaglandins Leukot Med pmid:6387721
Essien EM et al. Blood changes and enhanced thromboxane and 6-keto prostaglandin F1 alpha production in experimental acute Plasmodium bergei infection in hamsters. 1984 Thromb. Haemost. pmid:6388013
Mäkäräinen L and Ylikorkala O Amniotic fluid 6-keto-prostaglandin F1 alpha and thromboxane B2 during labor. 1984 Am. J. Obstet. Gynecol. pmid:6388335
Baughman RP et al. Prostaglandins and thromboxanes in the bronchoalveolar lavage fluid: possible immunoregulation in sarcoidosis. 1984 Am. Rev. Respir. Dis. pmid:6388445
Sekiya K and Okuda H Inhibitory action of soluble elastin on thromboxane B2 formation in blood platelets. 1984 Biochim. Biophys. Acta pmid:6320905
Fitscha P et al. Follow-up of in-vivo platelet function (platelet half-life, thromboxane B2) in patients with coronary heart disease. 1984 VASA pmid:6516563
Block HU et al. Estimation of thromboxane B2 in the clotting human whole blood by gas chromatography. 1984 Biomed. Biochim. Acta pmid:6517904
Beitz A et al. Thromboxane B2 (TXB2) formation in clotting whole blood of healthy and diabetic humans in vitro. 1984 Biomed. Biochim. Acta pmid:6517908
Keinänen-Kiukaanniemi S et al. Decreased thromboxane production in migraine patients during headache-free period. 1984 Headache pmid:6519984
Uehara Y et al. [A solid phase direct radioimmunoassay for urinary thromboxane B2 and its clinical application]. 1984 Nihon Jinzo Gakkai Shi pmid:6527429
Wang JP et al. Antiplatelet effect of capsaicin. 1984 Thromb. Res. pmid:6528310
Sedor JR et al. Effects of sulindac and indomethacin on renal prostaglandin synthesis. 1984 Clin. Pharmacol. Ther. pmid:6428794
Goodman MG and Weigle WO Regulation of B-lymphocyte proliferative responses by arachidonate metabolites: effects on membrane-directed versus intracellular activators. 1984 J. Allergy Clin. Immunol. pmid:6432883
Robson MC et al. A new explanation for the progressive tissue loss in electrical injuries. 1984 Plast. Reconstr. Surg. pmid:6422484
McGoon MD and Vanhoutte PM Aggregating platelets contract isolated canine pulmonary arteries by releasing 5-hydroxytryptamine. 1984 J. Clin. Invest. pmid:6470141
Lampugnani MG and de Gaetano G Effects of metabolized and unmetabolized arachidonate on rat platelet shape change. 1984 Am. J. Physiol. pmid:6433724
Salmon JA et al. Benoxaprofen does not inhibit formation of leukotriene B4 in a model of acute inflammation. 1984 Biochem. Pharmacol. pmid:6089840
Lefkowith JB et al. Macrophage-dependent arachidonate metabolism in hydronephrosis. 1984 Kidney Int. pmid:6434790
Stuart MJ et al. Differences in thromboxane production between neonatal and adult platelets in response to arachidonic acid and epinephrine. 1984 Pediatr. Res. pmid:6435080
Tanganelli I et al. Effects of somatostatin on the behavior of thromboxane B2 and B-thromboglobulin in type 1 diabetes. 1984 Boll. Soc. Ital. Biol. Sper. pmid:6084513
Goldyne ME Heterogeneity in leukocyte preparations: effects on defining eicosanoid metabolism by human lymphocytes and monocytes. 1984 J. Allergy Clin. Immunol. pmid:6088610
Pickard JD et al. Arterial eicosanoid production following chronic exposure to a periarterial haematoma. 1984 J. Neurol. Neurosurg. Psychiatr. pmid:6589362
Pan IQ et al. Alteration of platelet responses to metabolites of arachidonic acid by oral contraceptives. 1984 Br. J. Haematol. pmid:6089860
Serhan CN et al. Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate. 1984 Prostaglandins pmid:6328582
Shohami E and Sidi A Accumulation of prostacyclin in rat brain during haemorrhagic hypotension--possible role of PGI2 in autoregulation. 1984 J. Cereb. Blood Flow Metab. pmid:6363432
Higashihara M et al. Interaction of Solanum tuberosum agglutinin with human platelets. 1984 Biochem. Biophys. Res. Commun. pmid:6732807
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by capillary gas chromatography and negative ion chemical ionization mass spectrometry. 1984 J. Chromatogr. pmid:6736155
Simberg N Maternal aspirin administration inhibits pulmonary arachidonic acid metabolism in fetal rabbits. 1984 Prostaglandins Leukot Med pmid:6425868
Rao GH et al. Enteric-coated aspirin, platelet cyclooxygenase activity and function. 1984 Prostaglandins Leukot Med pmid:6425869
Burghuber O et al. Lung edema due to hydrogen peroxide is independent of cyclooxygenase products. 1984 J Appl Physiol Respir Environ Exerc Physiol pmid:6427146
Iacopino VJ et al. Responses to leukotriene C4 in the perfused rat lung. 1984 J. Pharmacol. Exp. Ther. pmid:6427447
Roth DM et al. Effects of lipoxygenase inhibitors in arachidonate-induced sudden death. 1984 J. Pharm. Pharmacol. pmid:6144761
Kerry R et al. Beta-adrenoceptor antagonists and human platelets: relationship of effects to lipid solubility. 1984 Biochem. Pharmacol. pmid:6147145
Worthington RE and Fuller GC Dibutyryl cyclic guanosine monophosphate elevates bovine endothelial cell thromboxane production without affecting prostacyclin metabolism. 1984 Thromb. Res. pmid:6322377
Holgate ST and Robinson C 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-Prostaglandin I1, (U-60,257) stimulates prostaglandin D2 and inhibits thromboxane B2 release from ionophore challenged human dispersed lung cells. 1984 Br. J. Pharmacol. pmid:6439267
Foegh ML et al. Urine thromboxane as an immunologic monitor in kidney transplant patients. 1984 Transplant. Proc. pmid:6390872
Foegh ML et al. Monitoring of rat heart allograft rejection by urinary thromboxane. 1984 Transplant. Proc. pmid:6390873
Willerson JT et al. Conversion from chronic to acute coronary artery disease: speculation regarding mechanisms. 1984 Am. J. Cardiol. pmid:6391133
Fareed J et al. Molecular markers of contrast media-induced adverse reactions. 1984 Semin. Thromb. Hemost. pmid:6393351
Holgate ST et al. Anaphylactic- and calcium-dependent generation of prostaglandin D2 (PGD2), thromboxane B2, and other cyclooxygenase products of arachidonic acid by dispersed human lung cells and relationship to histamine release. 1984 J. Immunol. pmid:6206153
Burch RM and Halushka PV Alterations in extracellular calcium concentration differentially influence prostaglandin and thromboxane synthesis in epithelial cells from the toad urinary bladder. 1984 Arch. Biochem. Biophys. pmid:6422855
Crutchley DJ Effects of inhibitors of arachidonic acid metabolism on thromboplastin activity in human monocytes. 1984 Biochem. Biophys. Res. Commun. pmid:6422935
DeRubertis FR et al. Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products. 1984 J. Clin. Invest. pmid:6438153
Axelrod L and Cornelius P Plasma prostaglandin levels and circulating fuel levels in rats with diabetic ketoacidosis: effects of cyclooxygenase inhibitors and of alpha and beta adrenergic blockade. 1984 Prostaglandins pmid:6440213
Zimmermann I et al. [Influence of vagus nerve, histamine, prostaglandin and catecholamine on airway obstruction]. 1984 Respiration pmid:6473921
Chan CC et al. Inhibition of prostanoid-mediated platelet aggregation in vivo and in vitro by 3-hydroxymethyl-dibenzo(b,f)thiepin 5,5-dioxide (L-640,035). 1984 J. Pharmacol. Exp. Ther. pmid:6423813
Higgins AJ and Lees P Arachidonic acid metabolites in carrageenin-induced equine inflammatory exudate. 1984 J. Vet. Pharmacol. Ther. pmid:6423835
Krell RD and Kusner EJ Differential effect of cyclo-oxygenase inhibition on antigen- and ionophore-induced release of slow reacting substance from fragmented guinea-pig lung. 1984 Br. J. Pharmacol. pmid:6434013
Yarom R et al. The effect of T-2 toxin on human platelets. 1984 Toxicol. Appl. Pharmacol. pmid:6710522
Walenga RW et al. Recovery of megakaryocyte thromboxane production in vitro after aspirin inhibition. 1984 Biochem. Biophys. Res. Commun. pmid:6712680
Lefer AM et al. Pathophysiological mechanisms of sudden death induced by platelet activating factor. 1984 Br. J. Pharmacol. pmid:6435705
Zipser RD and Smorlesi C Regulation of urinary thromboxane B2 in man: influence of urinary flow rate and tubular transport. 1984 Prostaglandins pmid:6718753
Cremer KF et al. Effects of diltiazem, dipyridamole, and their combination on hemostasis. 1984 Clin. Pharmacol. Ther. pmid:6435926
Kutti J et al. The effect of acetylsalicylic acid in 3 different formulations on in vitro and in vivo platelet function tests. An experimental study on healthy male volunteers. 1984 Scand J Haematol pmid:6719042
Holme S et al. The effect of albumin bound polyunsaturated fatty acids on human platelets. 1984 Thromb. Haemost. pmid:6719386
Pedersen AK and FitzGerald GA Dose-related kinetics of aspirin. Presystemic acetylation of platelet cyclooxygenase. 1984 N. Engl. J. Med. pmid:6436696
Eldor A et al. The effect of oral administration of dipyrone on the capacity of blood platelets to synthesize thromboxane A2 in man. 1984 Eur. J. Clin. Pharmacol. pmid:6723755
Cerletti C et al. Plasma levels of salicylate and aspirin in healthy volunteers: relevance to drug interaction on platelet function. 1984 J. Lab. Clin. Med. pmid:6726057
Anderson CB et al. Renal thromboxane synthesis in excised kidney distal to renovascular lesions. 1984 JAMA pmid:6726983
Rehr RB et al. Mechanism of nitroglycerin-induced coronary dilatation: lack of relation to intracoronary thromboxane concentrations. 1984 Am. J. Cardiol. pmid:6437206
Tremoli E et al. Increased platelet sensitivity and thromboxane B2 formation in type-II hyperlipoproteinaemic patients. 1984 Eur. J. Clin. Invest. pmid:6437830