Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Reese EA et al. | Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder. | 2012 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22841517 |
| Postula M et al. | Association of plasma concentrations of salicylic acid and high on ASA platelet reactivity in type 2 diabetes patients. | 2013 | Cardiol J | pmid:23558875 |
| Honma S et al. | Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. | 2013 | Eur. J. Pharmacol. | pmid:23747596 |
| Lee JJ et al. | Antithrombotic and antiplatelet activities of Soshiho-tang extract. | 2013 | BMC Complement Altern Med | pmid:23773779 |
| Kim YJ | Rhamnetin attenuates melanogenesis by suppressing oxidative stress and pro-inflammatory mediators. | 2013 | Biol. Pharm. Bull. | pmid:23739488 |
| Gremmel T et al. | Differential impact of inflammation on six laboratory assays measuring residual arachidonic acid-inducible platelet reactivity during dual antiplatelet therapy. | 2013 | J. Atheroscler. Thromb. | pmid:23739624 |
| Nakamura A et al. | Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension. | 2013 | Circ. J. | pmid:23676973 |
| Wu G et al. | Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. | 2013 | Chem. Pharm. Bull. | pmid:23207681 |
| Vazzana N et al. | Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype. | 2013 | J Am Heart Assoc | pmid:23557750 |
| Shi JJ and Huang LF | [Effects of transcutaneous electrical acupoint stimulation of "Zusanli" (ST 36) on gastric mucosal injury in exercise stress-induced gastric ulcer rats]. | 2013 | Zhen Ci Yan Jiu | pmid:24006661 |
| Steib CJ et al. | Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension. | 2013 | Life Sci. | pmid:24007798 |
| DeFilippis AP et al. | Thromboxane A(2) generation, in the absence of platelet COX-1 activity, in patients with and without atherothrombotic myocardial infarction. | 2013 | Circ. J. | pmid:23985963 |
| Siennicka A et al. | Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? | 2013 | J. Physiol. Pharmacol. | pmid:23959729 |
| Kleinbongard P et al. | Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris. | 2013 | Am. J. Physiol. Heart Circ. Physiol. | pmid:23934849 |
| Chen LB et al. | [Coagulation and prothrombotic state parameters: clinical analysis in early pregnancy]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24284247 |
| Santilli F et al. | Effects of high-amount-high-intensity exercise on in vivo platelet activation: modulation by lipid peroxidation and AGE/RAGE axis. | 2013 | Thromb. Haemost. | pmid:24030807 |
| Dave M and Amin AR | Yin-Yang regulation of prostaglandins and nitric oxide by PGD2 in human arthritis: reversal by celecoxib. | 2013 | Immunol. Lett. | pmid:23603366 |
| Kapłon-Cieślicka A et al. | Predictors of high platelet reactivity during aspirin treatment in patients with type 2 diabetes. | 2013 | Kardiol Pol | pmid:24065375 |
| Jastrzębska M et al. | Factors influencing multiplate whole blood impedance platelet aggregometry measurements, during aspirin treatment in acute ischemic stroke: a pilot study. | 2013 | Blood Coagul. Fibrinolysis | pmid:24071649 |
| Lv GY et al. | Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. | 2013 | J Ethnopharmacol | pmid:24080032 |
| Li H et al. | Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2. | 2013 | PLoS ONE | pmid:24098505 |
| Hau CS et al. | Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. | 2013 | J. Dermatol. Sci. | pmid:23688403 |
| Drew RC et al. | Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans. | 2013 | J. Appl. Physiol. | pmid:23970529 |
| An J et al. | Blocking of thromboxane Aâ‚‚ receptor attenuates airway mucus hyperproduction induced by cigarette smoke. | 2013 | Eur. J. Pharmacol. | pmid:23399768 |
| Leclerc P et al. | Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:24045148 |
| Bai L et al. | [Effects of electro-acupuncture at Zusanli point on gastric and intestinal blood flow in rats with acute necrotizing pancreatitis]. | 2013 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:24490517 |
| Aukema HM et al. | Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome. | 2013 | Br. J. Nutr. | pmid:23151363 |
| Yamamoto M et al. | Effects of continuous ingestion of hesperidin and glucosyl hesperidin on vascular gene expression in spontaneously hypertensive rats. | 2013 | J. Nutr. Sci. Vitaminol. | pmid:24418882 |
| Sun Y et al. | Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats. | 2013 | J Ethnopharmacol | pmid:24041459 |
| d'Emmanuele di Villa Bianca R et al. | Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24019484 |
| Kong X et al. | High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats. | 2013 | J. Vasc. Surg. | pmid:23069071 |
| Brose SA and Golovko MY | Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24113545 |
| Sayers BC et al. | Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23642096 |
| Zulyniak MA et al. | Fish oil supplementation alters circulating eicosanoid concentrations in young healthy men. | 2013 | Metab. Clin. Exp. | pmid:23522836 |
| Reyes JJ et al. | Antiplatelet effect of new lipophilic hydroxytyrosol alkyl ether derivatives in human blood. | 2013 | Eur J Nutr | pmid:22584413 |
| Vasudevan C et al. | The effect of parenteral lipid emulsions on pulmonary hemodynamics and eicosanoid metabolites in preterm infants: a pilot study. | 2013 | Nutr Clin Pract | pmid:24177284 |
| Matsunobu T et al. | Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. | 2013 | J. Lipid Res. | pmid:24009185 |
| Sadilkova L et al. | The effect of selected pre-analytical phase variables on plasma thromboxane Aâ‚‚ measurements in humans. | 2013 | Int J Lab Hematol | pmid:22908995 |
| Brentnall C et al. | Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves. | 2013 | J. Vet. Pharmacol. Ther. | pmid:22913421 |
| Yi X et al. | Platelet response to aspirin in Chinese stroke patients is independent of genetic polymorphisms of COX-1 C50T and COX-2 G765C. | 2013 | J. Atheroscler. Thromb. | pmid:22972377 |
| Barillà F et al. | Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention. | 2013 | Platelets | pmid:22646157 |
| Broekema FI et al. | In vivo hemostatic efficacy of polyurethane foam compared to collagen and gelatin. | 2013 | Clin Oral Investig | pmid:22855267 |
| McMahon GS et al. | Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial. | 2013 | Thromb. Haemost. | pmid:23494053 |
| Dharmasaroja PA et al. | Aspirin nonresponders in patients with ischaemic stroke. | 2013 | Blood Coagul. Fibrinolysis | pmid:23429255 |
| Shiraishi M et al. | Cholesterol enrichment of rabbit platelets enhances the Ca(2+) entry pathway induced by platelet-derived secondary feedback agonists. | 2013 | Life Sci. | pmid:23499558 |
| Larsen SB et al. | Reduced antiplatelet effect of aspirin is associated with low-grade inflammation in patients with coronary artery disease. | 2013 | Thromb. Haemost. | pmid:23407706 |
| Lino-dos-Santos-Franco A et al. | Formaldehyde inhalation reduces respiratory mechanics in a rat model with allergic lung inflammation by altering the nitric oxide/cyclooxygenase-derived products relationship. | 2013 | Food Chem. Toxicol. | pmid:23871789 |
| Fox T et al. | Dysregulated heme oxygenase-ferritin system in pterygium pathogenesis. | 2013 | Cornea | pmid:23792437 |
| Borst O et al. | Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation. | 2013 | Cell. Physiol. Biochem. | pmid:23817201 |
| Zhang J et al. | Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats. | 2013 | J Ethnopharmacol | pmid:23685195 |
| Wei XJ et al. | Effects of carboxymethylpachymaran on signal molecules in chicken immunocytes. | 2013 | Int. J. Biol. Macromol. | pmid:23664932 |
| Kang JW et al. | Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans. | 2013 | Phytother Res | pmid:23296979 |
| Snider AJ et al. | Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis. | 2013 | PLoS ONE | pmid:23301082 |
| Xue YT et al. | Effect of anger on endothelial-derived vasoactive factors in spontaneously hypertensive rats. | 2013 | Heart Lung Circ | pmid:23261325 |
| Gao H et al. | Effects of Yerba Mate tea (Ilex paraguariensis) on vascular endothelial function and liver lipoprotein receptor gene expression in hyperlipidemic rats. | 2013 | Fitoterapia | pmid:23266732 |
| Carroll RC et al. | A comparison of VerifyNowR with PlateletMappingR--detected aspirin resistance and correlation with urinary thromboxane. | 2013 | Anesth. Analg. | pmid:23302970 |
| Towhid ST et al. | Stimulation of platelet death by vancomycin. | 2013 | Cell. Physiol. Biochem. | pmid:23363637 |
| Ren R et al. | Modulation of platelet aggregation-related eicosanoid production by dietary F-fucoidan from brown alga Laminaria japonica in human subjects. | 2013 | Br. J. Nutr. | pmid:23374164 |
| Gautier-Veyret E et al. | Intermittent hypoxia-activated cyclooxygenase pathway: role in atherosclerosis. | 2013 | Eur. Respir. J. | pmid:23060635 |
| Kovarik JJ et al. | Eicosanoid modulation by the short-chain fatty acid n-butyrate in human monocytes. | 2013 | Immunology | pmid:23398566 |
| Xue J et al. | Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats. | 2013 | Chin J Integr Med | pmid:23001461 |
| Maenthaisong R et al. | Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755755 |
| Dudley A et al. | Cyclooxygenase expression and platelet function in healthy dogs receiving low-dose aspirin. | 2013 Jan-Feb | J. Vet. Intern. Med. | pmid:23278865 |
| John F et al. | Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin. | 2013 May-Jun | Indian Heart J | pmid:23809385 |
| Yu C et al. | Effects of danshensu on platelet aggregation and thrombosis: in vivo arteriovenous shunt and venous thrombosis models in rats. | 2014 | PLoS ONE | pmid:25375124 |
| Ross S et al. | Association of cyclooxygenase-2 genetic variant with cardiovascular disease. | 2014 | Eur. Heart J. | pmid:24796340 |
| Salazar F et al. | Renal effects induced by prolonged mPGES1 inhibition. | 2014 | Am. J. Physiol. Renal Physiol. | pmid:24197070 |
| Kawai VK et al. | Suboptimal inhibition of platelet cyclooxygenase 1 by aspirin in systemic lupus erythematosus: association with metabolic syndrome. | 2014 | Arthritis Care Res (Hoboken) | pmid:24022862 |
| Elsheikh W et al. | Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer. | 2014 | Nitric Oxide | pmid:24747869 |
| Suarez-Kurtz G | Impact of CYP2C9*3/*3 genotype on the pharmacokinetics and pharmacodynamics of oxicam NSAIDs. | 2014 | Pharmacogenet. Genomics | pmid:25003537 |
| Lee HI et al. | Response to Suarez-Kurtz's comments on strongly increased exposure of meloxicam in CYP2C9*3/*3 individuals. | 2014 | Pharmacogenet. Genomics | pmid:25003538 |
| Shan MQ et al. | [Comparative study on effects of Rubiae Radix et Rhizoma and carbonized Rubiae Radix et Rhizoma on acute blood stasis rat model]. | 2014 | Zhongguo Zhong Yao Za Zhi | pmid:24946554 |
| Zhou K et al. | A CAPE analogue as novel antiplatelet agent efficiently inhibits collagen-induced platelet aggregation. | 2014 | Pharmazie | pmid:25158573 |
| Maurer K et al. | Acetylsalicylic acid enhances tachyphylaxis of repetitive capsaicin responses in TRPV1-GFP expressing HEK293 cells. | 2014 | Neurosci. Lett. | pmid:24495935 |
| Shimizu T et al. | Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation. | 2014 | Pflugers Arch. | pmid:23995773 |
| Umar A et al. | Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis. | 2014 | J Ethnopharmacol | pmid:24412551 |
| Sahota T et al. | Model-based analysis of thromboxane Bâ‚‚ and prostaglandin Eâ‚‚ as biomarkers in the safety evaluation of naproxen. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24667227 |
| Gonçalves LH et al. | Acetylsalicylic acid therapy: influence of metformin use and other variables on urinary 11-dehydrothromboxane B2 levels. | 2014 | Clin. Chim. Acta | pmid:24316050 |
| Jiménez-Romero C et al. | Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24279991 |
| Lee HI et al. | Strongly increased exposure of meloxicam in CYP2C9*3/*3 individuals. | 2014 | Pharmacogenet. Genomics | pmid:24322170 |
| Voisin V et al. | Protection of Wistar-Furth rats against postischaemic acute renal injury: role for nitric oxide and thromboxane? | 2014 | Clin. Exp. Pharmacol. Physiol. | pmid:25115485 |
| Zhu Y et al. | Effects and mechanisms of Fenofibrate on the secretion of vascular endothelial contraction factors in hypertensive rats. | 2014 | Genet. Mol. Res. | pmid:25078582 |
| Tachi M et al. | Mass spectrometric determination of prostanoids in rat hypothalamic paraventricular nucleus microdialysates. | 2014 | Auton Neurosci | pmid:24447364 |
| Montserrat-de la Paz S et al. | Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. | 2014 | J Ethnopharmacol | pmid:24239848 |
| Wang Y et al. | DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4. | 2014 | BMC Complement Altern Med | pmid:24555740 |
| Santos-Gallego CG and Badimon JJ | The sum of two evils: pneumonia and myocardial infarction: is platelet activation the missing link? | 2014 | J. Am. Coll. Cardiol. | pmid:25444148 |
| Cangemi R et al. | Platelet activation is associated with myocardial infarction in patients with pneumonia. | 2014 | J. Am. Coll. Cardiol. | pmid:25444147 |
| Shinohara M et al. | Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1. | 2014 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25217660 |
| Hong S et al. | Maresin-like lipid mediators are produced by leukocytes and platelets and rescue reparative function of diabetes-impaired macrophages. | 2014 | Chem. Biol. | pmid:25200603 |
| Tong B et al. | [Atorvastatin inhibits platelet aggregation and activation following carotid balloon injury in cholesterol-fed rabbits]. | 2014 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:25176087 |
| Kaplon-Cieslicka A et al. | Younger age, higher body mass index and lower adiponectin concentration predict higher serum thromboxane B2 level in aspirin-treated patients with type 2 diabetes: an observational study. | 2014 | Cardiovasc Diabetol | pmid:25123549 |
| Hayashi G et al. | Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia. | 2014 | Hum. Mol. Genet. | pmid:25104852 |
| Floyd CN et al. | Increased platelet expression of glycoprotein IIIa following aspirin treatment in aspirin-resistant but not aspirin-sensitive subjects. | 2014 | Br J Clin Pharmacol | pmid:25099258 |
| Zhu SH et al. | Protective effect of indomethacin in renal ischemia-reperfusion injury in mice. | 2014 | J Zhejiang Univ Sci B | pmid:25091992 |
| Basili S et al. | Aspirin reload before elective percutaneous coronary intervention: impact on serum thromboxane b2 and myocardial reperfusion indexes. | 2014 | Circ Cardiovasc Interv | pmid:25074252 |
| Lattanzio S et al. | Circulating dickkopf-1 in diabetes mellitus: association with platelet activation and effects of improved metabolic control and low-dose aspirin. | 2014 | J Am Heart Assoc | pmid:25037197 |
| Santilli F et al. | Circulating myeloid-related protein-8/14 is related to thromboxane-dependent platelet activation in patients with acute coronary syndrome, with and without ongoing low-dose aspirin treatment. | 2014 | J Am Heart Assoc | pmid:25037196 |
| Patrignani P et al. | Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action. | 2014 | J. Thromb. Haemost. | pmid:24942808 |
| Mayer AM et al. | Vibrio vulnificus MO6-24/O lipopolysaccharide stimulates superoxide anion, thromboxane Bâ‚‚, matrix metalloproteinase-9, cytokine and chemokine release by rat brain microglia in vitro. | 2014 | Mar Drugs | pmid:24675728 |
| van den Elsen LW et al. | Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. | 2014 | J. Hypertens. | pmid:24569415 |